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Generation of HIV- and CD19-Specific TSCM CAR-T Cells by a Novel Cytokine-Based Scaffold 通过新型基于细胞因子的支架产生HIV和CD19-Specific TSCM car-t细胞 Cole, Erin Beverly; Lamcaj, Sara; Sydenstricker, Agnes; Shrestha, Niraj; Hiner, Christopher; Zheng, Jian Hua; Zhu, Zhongyu; Xiong, Ying; Dropulic, Boro; Wong, Hing C.; Goldstein, Harris 分享 收藏
Correlation of chemotherapy-induced alopecia and quality of life among breast cancer patients undergoing scalp cooling device during chemotherapy Yeo, W.; Mo, F.; Li, L.; Lau, T.; So, H.; Lui, D.; Wong, H.; Leung, E.; Chan, D.; Yeo, H.; Lai, K.; Pang, E.; Li, Y.; Kwok, C. 分享 收藏
Prospective study assessing the efficacy and safety of a scalp cooling device for the prevention of alopecia in breast cancer patients undergoing (neo)adjuvant chemotherapy Yeo, W.; Kwok, C. C. H.; Lau, T.; Lai, K.; Li, L.; Leung, E.; Chan, D.; Wong, H.; Lui, D.; So, H.; Li, Y.; Yeo, H.; Pang, E.; Mo, F. 分享 收藏
Bifunctional immunotherapeutic HCW9218 facilitates recruitment of immune cells from tumor draining lymph nodes to promote antitumor activity and enhance checkpoint blockade efficacy in solid tumors George, Varghese; Chaturvedi, Pallavi; Shrestha, Niraj; Kanakraj, Leah; Gilkes, Crystal; Encalada, Nicole; Wang, Meng; Zhu, Xiaoyun; Liu, Bai; Rhode, Peter; Wong, Hing C. 分享 收藏
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Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice 减少小鼠衰老细胞和缓解衰老相关分泌表型的免疫治疗方法 Shrestha, Niraj; Chaturvedi, Pallavi; Zhu, Xiaoyun; Dee, Michael J.; George, Varghese; Janney, Christopher; Egan, Jack O.; Liu, Bai; Foster, Mark; Marsala, Lynne; Wong, Pamela; Cubitt, Celia C.; Foltz, Jennifer A.; Tran, Jennifer; Schappe, Timothy; Hsiao, Karin; Leclerc, Gilles M.; You, Lijing; Echeverri, Christian; Spanoudis, Catherine; Carvalho, Ana; Kanakaraj, Leah; Gilkes, Crystal; Encalada, Nicole; Kong, Lin; Wang, Meng; Fang, Byron; Wang, Zheng; Jiao, Jin-an; Muniz, Gabriela J.; Jeng, Emily K.; Valdivieso, Nicole; Li, Liying; Deth, Richard; Berrien-Elliott, Melissa M.; Fehniger, Todd A.; Rhode, Peter R.; Wong, Hing C. 分享 收藏
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice Zhu, Xiaoyun; Li, Qiongzhen; George, Varghese; Spanoudis, Catherine; Gilkes, Crystal; Shrestha, Niraj; Liu, Bai; Kong, Lin; You, Lijing; Echeverri, Christian; Li, Liying; Wang, Zheng; Chaturvedi, Pallavi; Muniz, Gabriela J.; Egan, Jack O.; Rhode, Peter R.; Wong, Hing C. 分享 收藏
A feeder cell-free activation and expansion strategy to generate memory-like NK cells sufficient for off-the-shelf multi-dose adoptive cell therapy Wong, Hing C.; Dee, Michael J.; Shrestha, Niraj; Chaturvedi, Pallavi; Leclerc, Giles M.; Zhu, Xiaoyun; Liu, Bai; Kong, Lin; Echeverri, Christian A.; You, Lijing; Egan, Jack O.; Jiao, Jin-An; Rhode, Peter R.; Becker-Hapak, Michelle K.; Berrien-Elliott, Melissa M.; McClain, Ethan; Foster, Mark; Pence, Patrick; Neal, Carly C.; Kersting-Schadek, Samantha; Fehniger, Todd A. 分享 收藏
Immunotherapeutic HCW9218 augments anti-tumor activity of chemotherapy via NK cell-mediated reduction of therapy-induced senescent cells Chaturvedi, Pallavi; George, Varghese; Shrestha, Niraj; Wang, Meng; Dee, Michael J.; Zhu, Xiaoyun; Liu, Bai; Egan, Jack; D'Eramo, Francesca; Spanoudis, Catherine; Gallo, Victor; Echeverri, Christian; You, Lijing; Kong, Lin; Fang, Byron; Jeng, Emily K.; Rhode, Peter R.; Wong, Hing C. 分享 收藏
Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial Miller, Jeffrey S.; Davis, Zachary B.; Helgeson, Erika; Reilly, Cavan; Thorkelson, Ann; Anderson, Jodi; Lima, Noemia S.; Jorstad, Siri; Hart, Geoffrey T.; Lee, John H.; Safrit, Jeffrey T.; Wong, Hing; Cooley, Sarah; Gharu, Lavina; Chung, Hyunsoo; Soon-Shiong, Patrick; Dobrowolski, Curtis; Fletcher, Courtney, V; Karn, Jonathan; Douek, Daniel C.; Schacker, Timothy W. 分享 收藏
Bifunctional TGF-β trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors Liu, Bai; Zhu, Xiaoyun; Kong, Lin; Wang, Meng; Spanoudis, Catherine; Chaturvedi, Pallavi; George, Varghese; Jiao, Jin-An; You, Lijing; Egan, Jack O.; Echeverri, Christian; Gallo, Victor L.; Xing, Jilan; Ravelo, Kristine; Prendes, Caitlin; Antolinez, Julian; Denissova, Julia; Muniz, Gabriela J.; Jeng, Emily K.; Rhode, Peter R.; Wong, Hing C. 分享 收藏
The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex Jochems, Caroline; Tritsch, Sarah R.; Knudson, Karin M.; Gameiro, Sofia R.; Rumfield, Claire Smalley; Pellom, Samuel T.; Morillon, Y. Maurice, II; Newman, Robby; Marcus, Warren; Szeto, Christopher; Rabizadeh, Shahrooz; Wong, Hing C.; Soon-Shiong, Patrick; Schlom, Jeffrey 分享 收藏
Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors 新型重组IL15复合物ALT-803在晚期实体瘤患者中的I期试验 Margolin, Kim; Morishima, Chihiro; Velcheti, Vamsidhar; Miller, Jeffrey S.; Lee, Sylvia M.; Silk, Ann W.; Holtan, Shernan G.; Lacroix, Andreanne M.; Fling, Steven P.; Kaiser, Judith C.; Egan, Jack O.; Jones, Monica; Rhode, Peter R.; Rock, Amy D.; Cheever, Martin A.; Wong, Hing C.; Ernstoff, Marc S. 分享 收藏
Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery 通过TCR信号响应性纳米颗粒药物递送增强T细胞治疗 Tang, Li; Zheng, Yiran; Melo, Mariane Bandeira; Mabardi, Llian; Castano, Ana P.; Xie, Yu-Qing; Li, Na; Kudchodkar, Sagar B.; Wong, Hing C.; Jeng, Emily K.; Maus, Marcela V.; Irvine, Darrell J. 分享 收藏
First-in-human phase I combination of the IL-15 receptor super agonist complex ALT-803 with a therapeutic (anti-CD20) monoclonal antibody (mAb) for patients with relapsed or refractory indolent non-Hodgkin lymphoma (iNHL) Fehniger, Todd A.; Hess, Brian T.; Bachanova, Veronika; Becker-Hapak, Michelle; McClain, Ethan; Berrien-Elliott, Melissa; Wagner, Julia; Bartlett, Nancy L.; Kahl, Brad; Mehta-Shah, Neha; Cashen, Amanda F.; Gao, Feng; Conradi, Kyle; Rock, Amy D.; Jeng, Emily K.; Hernandez, Liza; Egan, Jack O.; Rhode, Peter R.; Wong, Hing C. 分享 收藏
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Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models Liu, Bai; Jones, Monica; Kong, Lin; Noel, Terra; Jeng, Emily K.; Shi, Sixiang; England, Christopher G.; Alter, Sarah; Miller, Jeffrey S.; Cai, Weibo; Rhode, Peter R.; Wong, Hing C. 分享 收藏