Hop, Paul J.; Zwamborn, Ramona A. J.; Hannon, Eilis; Shireby, Gemma L.; Nabais, Marta F.; Walker, Emma M.; van Rheenen, Wouter; van Vugt, Joke J. F. A.; Dekker, Annelot M.; Westeneng, Henk-Jan; Tazelaar, Gijs H. P.; van Eijk, Kristel R.; Moisse, Matthieu; Baird, Denis; Al Khleifat, Ahmad; Iacoangeli, Alfredo; Ticozzi, Nicola; Ratti, Antonia; Cooper-Knock, Jonathan; Morrison, Karen E.; Shaw, Pamela J.; Basak, A. Nazli; Chio, Adriano; Calvo, Andrea; Moglia, Cristina; Canosa, Antonio; Brunetti, Maura; Grassano, Maurizio; Gotkine, Marc; Lerner, Yossef; Zabari, Michal; Vourc'h, Patrick; Corcia, Philippe; Couratier, Philippe; Pardina, Jesus S. Mora; Salas, Teresa; Dion, Patrick; Ross, Jay P.; Henderson, Robert D.; Mathers, Susan; McCombe, Pamela A.; Needham, Merrilee; Nicholson, Garth; Rowe, Dominic B.; Pamphlett, Roger; Mather, Karen A.; Sachdev, Perminder S.; Furlong, Sarah; Garton, Fleur C.; Henders, Anjali K.; Lin, Tian; Ngo, Shyuan T.; Steyn, Frederik J.; Wallace, Leanne; Williams, Kelly L.; Neto, Miguel Mitne; Cauchi, Ruben J.; Blair, Ian P.; Kiernan, Matthew C.; Drory, Vivian; Povedano, Monica; de Carvalho, Mamede; Pinto, Susana; Weber, Markus; Rouleau, Guy A.; Silani, Vincenzo; Landers, John E.; Shaw, Christopher E.; Andersen, Peter M.; McRae, Allan F.; van Es, Michael A.; Pasterkamp, R. Jeroen; Wray, Naomi R.; McLaughlin, Russell L.; Hardiman, Orla; Kenna, Kevin P.; Tsai, Ellen; Runz, Heiko; Al-Chalabi, Ammar; van den Berg, Leonard H.; Van Damme, Philip; Mill, Jonathan; Veldink, Jan H.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021)

肌萎缩性侧索硬化症的常见和罕见变异关联分析确定了15个具有不同遗传结构和神经元特异性生物学的风险位点 (第53卷，1636页，2021)

NATURE GENETICS

IF31.8

2022-01-311

OAAI

van Rheenen, Wouter; van der Spek, Rick A. A.; Bakker, Mark K.; van Vugt, Joke J. F. A.; Hop, Paul J.; Zwamborn, Ramona A. J.; de Klein, Niek; Westra, Harm-Jan; Bakker, Olivier B.; Deelen, Patrick; Shireby, Gemma; Hannon, Eilis; Moisse, Matthieu; Baird, Denis; Restuadi, Restuadi; Dolzhenko, Egor; Dekker, Annelot M.; Gawor, Klara; Westeneng, Henk-Jan; Tazelaar, Gijs H. P.; van Eijk, Kristel R.; Kooyman, Maarten; Byrne, Ross P.; Doherty, Mark; Heverin, Mark; Al Khleifat, Ahmad; Iacoangeli, Alfredo; Shatunov, Aleksey; Ticozzi, Nicola; Cooper-Knock, Johnathan; Smith, Bradley N.; Gromicho, Marta; Chandran, Siddharthan; Pal, Suvankar; Morrison, Karen E.; Shaw, Pamela J.; Hardy, John; Orrell, Richard W.; Sendtner, Michael; Meyer, Thomas; Basak, Nazli; van der Kooi, Anneke J.; Ratti, Antonia; Fogh, Isabella; Gellera, Cinzia; Lauria, Giuseppe; Corti, Stefania; Cereda, Cristina; Sproviero, Daisy; D'Alfonso, Sandra; Soraru, Gianni; Siciliano, Gabriele; Filosto, Massimiliano; Padovani, Alessandro; Chio, Adriano; Calvo, Andrea; Moglia, Cristina; Brunetti, Maura; Canosa, Antonio; Grassano, Maurizio; Beghi, Ettore; Pupillo, Elisabetta; Logroscino, Giancarlo; Nefussy, Beatrice; Osmanovic, Alma; Nordin, Angelica; Lerner, Yossef; Zabari, Michal; Gotkine, Marc; Baloh, Robert H.; Bell, Shaughn; Vourc'h, Patrick; Corcia, Philippe; Couratier, Philippe; Millecamps, Stephanie; Meininger, Vincent; Salachas, Francois; Mora Pardina, Jesus S.; Assialioui, Abdelilah; Rojas-Garcia, Ricardo; Dion, Patrick A.; Ross, Jay P.; Ludolph, Albert C.; Weishaupt, Jochen H.; Brenner, David; Freischmidt, Axel; Bensimon, Gilbert; Brice, Alexis; Durr, Alexandra; Payan, Christine A. M.; Saker-Delye, Safa; Wood, Nicholas W.; Topp, Simon; Rademakers, Rosa; Tittmann, Lukas; Lieb, Wolfgang; Franke, Andre; Ripke, Stephan; Braun, Alice; Kraft, Julia; Whiteman, David C.; Olsen, Catherine M.; Uitterlinden, Andre G.; Hofman, Albert; Rietschel, Marcella; Cichon, Sven; Nothen, Markus M.; Amouyel, Philippe; Comi, Giancarlo; Riva, Nilo; Lunetta, Christian; Gerardi, Francesca; Cotelli, Maria Sofia; Rinaldi, Fabrizio; Chiveri, Luca; Guaita, Maria Cristina; Perrone, Patrizia; Ceroni, Mauro; Diamanti, Luca; Ferrarese, Carlo; Tremolizzo, Lucio; Delodovici, Maria Luisa; Bono, Giorgio; Manera, Umberto; Vasta, Rosario; Bombaci, Alessandro; Casale, Federico; Fuda, Giuseppe; Salamone, Paolina; Iazzolino, Barbara; Peotta, Laura; Cugnasco, Paolo; De Marco, Giovanni; Torrieri, Maria Claudia; Palumbo, Francesca; Gallone, Salvatore; Barberis, Marco; Sbaiz, Luca; Gentile, Salvatore; Mauro, Alessandro; Mazzini, Letizia; De Marchi, Fabiola; Corrado, Lucia; D'Alfonso, Sandra; Bertolotto, Antonio; Gionco, Maurizio; Leotta, Daniela; Odddenino, Enrico; Imperiale, Daniele; Cavallo, Roberto; Pignatta, Pietro; De Mattei, Marco; Geda, Claudio; Papurello, Diego Maria; Gusmaroli, Graziano; Comi, Cristoforo; Labate, Carmelo; Ruiz, Luigi; Ferrandi, Delfina; Rota, Eugenia; Aguggia, Marco; Di Vito, Nicoletta; Meineri, Piero; Ghiglione, Paolo; Launaro, Nicola; Dotta, Michele; Di Sapio, Alessia; Giardini, Guido; Tiloca, Cinzia; Peverelli, Silvia; Taroni, Franco; Pensato, Viviana; Castellotti, Barbara; Comi, Giacomo P.; Del Bo, Roberto; Ceroni, Mauro; Gagliardi, Stella; Corrado, Lucia; Mazzini, Letizia; Raggi, Flavia; Simoncini, Costanza; Lo Gerfo, Annalisa; Inghilleri, Maurizio; Ferlini, Alessandra; Simone, Isabella L.; Passarella, Bruno; Guerra, Vito; Zoccolella, Stefano; Nozzoli, Cecilia; Mundi, Ciro; Leone, Maurizio; Zarrelli, Michele; Tamma, Filippo; Valluzzi, Francesco; Calabrese, Gianluigi; Boero, Giovanni; Rini, Augusto; Traynor, Bryan J.; Singleton, Andrew B.; Mitne Neto, Miguel; Cauchi, Ruben J.; Ophoff, Roel A.; Wiedau-Pazos, Martina; Lomen-Hoerth, Catherine; van Deerlin, Vivianna M.; Grosskreutz, Julian; Roediger, Annekathrin; Gaur, Nayana; Joerk, Alexander; Barthel, Tabea; Theele, Erik; Ilse, Benjamin; Stubendorff, Beatrice; Witte, Otto W.; Steinbach, Robert; Huebner, Christian A.; Graff, Caroline; Brylev, Lev; Fominykh, Vera; Demeshonok, Vera; Ataulina, Anastasia; Rogelj, Boris; Koritnik, Blaz; Zidar, Janez; Ravnik-Glavac, Metka; Glavac, Damjan; Stevic, Zorica; Drory, Vivian; Povedano, Monica; Blair, Ian P.; Kiernan, Matthew C.; Benyamin, Beben; Henderson, Robert D.; Furlong, Sarah; Mathers, Susan; McCombe, Pamela A.; Needham, Merrilee; Ngo, Shyuan T.; Nicholson, Garth A.; Pamphlett, Roger; Rowe, Dominic B.; Steyn, Frederik J.; Williams, Kelly L.; Mather, Karen A.; Sachdev, Perminder S.; Henders, Anjali K.; Wallace, Leanne; de Carvalho, Mamede; Pinto, Susana; Petri, Susanne; Weber, Markus; Rouleau, Guy A.; Silani, Vincenzo; Curtis, Charles J.; Breen, Gerome; Glass, Jonathan D.; Brown, Robert H., Jr.; Landers, John E.; Shaw, Christopher E.; Andersen, Peter M.; Groen, Ewout J. N.; van Es, Michael A.; Pasterkamp, R. Jeroen; Fan, Dongsheng; Garton, Fleur C.; McRae, Allan F.; Davey Smith, George; Gaunt, Tom R.; Eberle, Michael A.; Mill, Jonathan; McLaughlin, Russell L.; Hardiman, Orla; Kenna, Kevin P.; Wray, Naomi R.; Tsai, Ellen; Runz, Heiko; Franke, Lude; Al-Chalabi, Ammar; Van Damme, Philip; van den Berg, Leonard H.; Veldink, Jan H.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

肌萎缩性侧索硬化症的常见和罕见变异关联分析确定了15个具有不同遗传结构和神经元特异性生物学的风险位点

NATURE GENETICS

IF31.8

2021-12-06235

OAAI

The influence of adult hip shape genetic variants on adolescent hip shape: Findings from a population-based DXA study

BONE

IF3.6

2021-02-016

OAAI

Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual

全基因组关联研究涉及新的基因座，并揭示了纵向儿童骨骼累积的候选效应基因

GENOME BIOLOGY

IF9.4

2021-01-0416

OAAI

Cousminer, Diana L.; Wagley, Yadav; Pippin, James A.; Elhakeem, Ahmed; Way, Gregory P.; Pahl, Matthew C.; McCormack, Shana E.; Chesi, Alessandra; Mitchell, Jonathan A.; Kindler, Joseph M.; Baird, Denis; Hartley, April; Howe, Laura; Kalkwarf, Heidi J.; Lappe, Joan M.; Lu, Sumei; Leonard, Michelle E.; Johnson, Matthew E.; Hakonarson, Hakon; Gilsanz, Vicente; Shepherd, John A.; Oberfield, Sharon E.; Greene, Casey S.; Kelly, Andrea; Lawlor, Deborah A.; Voight, Benjamin F.; Wells, Andrew D.; Zemel, Babette S.; Hankenson, Kurt D.; Grant, Struan F. A.

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

全表型孟德尔随机化映射血浆蛋白质组对复杂疾病的影响

NATURE GENETICS

IF31.8

2020-09-07315

OAAI

Zheng, Jie; Haberland, Valeriia; Baird, Denis; Walker, Venexia; Haycock, Philip C.; Hurle, Mark R.; Gutteridge, Alex; Erola, Pau; Liu, Yi; Luo, Shan; Robinson, Jamie; Richardson, Tom G.; Staley, James R.; Elsworth, Benjamin; Burgess, Stephen; Sun, Benjamin B.; Danesh, John; Runz, Heiko; Maranville, Joseph C.; Martin, Hannah M.; Yarmolinsky, James; Laurin, Charles; Holmes, Michael V.; Liu, Jimmy Z.; Estrada, Karol; Santos, Rita; McCarthy, Linda; Waterworth, Dawn; Nelson, Matthew R.; Smith, George Davey; Butterworth, Adam S.; Hemani, Gibran; Scott, Robert A.; Gaunt, Tom R.

Subregional statistical shape modelling identifies lesser trochanter size as a possible risk factor for radiographic hip osteoarthritis, a cross-sectional analysis from the Osteoporotic Fractures in Men Study

OSTEOARTHRITIS AND CARTILAGE

IF9

2020-08-0112

OAAI

Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2019-06-0625

OAAI

Zheng, Jie; Maerz, Winfried; Gergei, Ingrid; Kleber, Marcus; Drechsler, Christiane; Wanner, Christoph; Brandenburg, Vincent; Reppe, Sjur; Gautvik, Kaare M.; Medina-Gomez, Carolina; Shevroja, Enisa; Gilly, Arthur; Park, Young-Chan; Dedoussis, George; Zeggini, Eleftheria; Lorentzon, Mattias; Henning, Petra; Lerner, Ulf H.; Nilsson, Karin; Moverare-Skrtic, Sofia; Baird, Denis; Elsworth, Benjamin; Falk, Louise; Groom, Alix; Capellini, Terence D.; Grundberg, Elin; Nethander, Maria; Ohlsson, Claes; Smith, George Davey; Tobias, Jonathan H.

Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X-Ray Absorptiometry-Derived Hip Shape in a Population-Based Cohort of Perimenopausal Women

ARTHRITIS & RHEUMATOLOGY

IF10.9

2018-10-2718

OAAI

Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2018-10-1547

OAAI

Baird, Denis A.; Evans, Daniel S.; Kamanu, Frederick K.; Gregory, Jennifer S.; Saunders, Fiona R.; Giuraniuc, Claudiu V.; Barr, Rebecca J.; Aspden, Richard M.; Jenkins, Deborah; Kiel, Douglas P.; Orwoll, Eric S.; Cummings, Steven R.; Lane, Nancy E.; Mullin, Benjamin H.; Williams, Frances M. K.; Richards, J. Brent; Wilson, Scott G.; Spector, Tim D.; Faber, Benjamin G.; Lawlor, Deborah A.; Grundberg, Elin; Ohlsson, Claes; Pettersson-Kymmer, Ulrika; Capellini, Terence D.; Richard, Daniel; Beck, Thomas J.; Evans, David M.; Paternoster, Lavinia; Karasik, David; Tobias, Jonathan H.

The MR-Base platform supports systematic causal inference across the human phenome

MR-Base平台支持跨人类表型组的系统因果推断

ELIFE

IF0

2018-05-304.4K

OAAI

THE GENETIC ARCHITECTURE OF HIP STATISTICAL SHAPE MODELS SUGGESTS THAT ENDOCHONDRAL BONE FORMATION MAKES AN IMPORTANT CONTRIBUTION TO HIP SHAPE

OSTEOARTHRITIS AND CARTILAGE

IF9

2018-04-010

OAAI

DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort