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A

Andrew Calinisan

mirati therapeutics, inc.
H指数:8
被引数:2,687

个人简介

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教育背景

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工作经历

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荣誉奖项

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The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading

SOS1抑制剂MRTX0902阻断KRAS激活并在依赖KRAS核苷酸负载的癌症中显示抗肿瘤活性

MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-04-194
OAAI
Sudhakar, Niranjan; Yan, Larry; Qiryaqos, Fadia; Engstrom, Lars D.; Laguer, Jade; Calinisan, Andrew; Hebbert, Allan; Waters, Laura; Moya, Krystal; Bowcut, Vickie; Vegar, Laura; Ketcham, John M.; Ivetac, Anthony; Smith, Christopher R.; Lawson, J. David; Rahbaek, Lisa; Clarine, Jeffrey; Nguyen, Natalie; Saechao, Barbara; Parker, Cody; Elliott, Adam J.; Vanderpool, Darin; He, Leo; Hover, Laura D.; Fernandez-Banet, Julio; Coma, Silvia; Pachter, Jonathan A.; Hallin, Jill; Marx, Matthew A.; Briere, David M.; Christensen, James G.; Olson, Peter; Haling, Jacob; Khare, Shilpi
Discovery of ORIC-944, a novel inhibitor of PRC2 with best-in-class properties for the treatment of prostate cancer
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Marx, Matthew A.; Burns, Aaron C.; Arora, Nidhi; Bobinski, Thomas P.; Briere, David M.; Calinisan, Andrew; Gunn, Robin J.; Ketcham, John M.; Lawson, David; Lee, Matthew; Olson, Peter; Smith, Christopher R.; Sudhakar, Niranjan; Christensen, James G.; Chen, Chelsea X.; Yuen, Natalie; Ulicna, Livia; Duong, Frank; Colas, Christophe; Ramnath, Anjana; Xu, Ron; Maneval, Edna Chow; Multani, Pratik S.; Patel, Rupal; Kumar, Archana; Daemen, Anneleen; Romero, Anthony; Junttila, Melissa R.; Friedman, Lori S.
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-03-133
OAAI
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M.; Briere, David M.; Burns, Aaron C.; Haatveit, Kersti Caddell; Calinisan, Andrew; Clarine, Jeffery; Elliott, Adam; Engstrom, Lars D.; Gunn, Robin J.; Ivetac, Anthony; Jones, Benjamin; Kuehler, Jon; Lawson, J. David; Nguyen, Natalie; Parker, Cody; Pearson, Kelly E.; Rahbaek, Lisa; Saechao, Barbara; Wang, Xiaolun; Waters, Anna; Waters, Laura; Watkins, Ashlee H.; Olson, Peter; Smith, Christopher R.; Christensen, James G.; Marx, Matthew A.
Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor

一种有效的选择性非共价KRASG12D抑制剂的抗肿瘤功效

NATURE MEDICINE
IF50
2022-10-10207
OA
Hallin, Jill; Bowcut, Vickie; Calinisan, Andrew; Briere, David M.; Hargis, Lauren; Engstrom, Lars D.; Laguer, Jade; Medwid, James; Vanderpool, Darin; Lifset, Ella; Trinh, David; Hoffman, Natalie; Wang, Xiaolun; Lawson, J. David; Gunn, Robin J.; Smith, Christopher R.; Thomas, Nicole C.; Martinson, Matthew; Bergstrom, Alex; Sullivan, Francis; Bouhana, Karyn; Winski, Shannon; He, Leo; Fernandez-Banet, Julio; Pavlicek, Adam; Haling, Jacob R.; Rahbaek, Lisa; Marx, Matthew A.; Olson, Peter; Christensen, James G.
Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor

鉴定非共价，有效和选择性的KRASG12D抑制剂MRTX1133

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-12-10354
OA
Wang, Xiaolun; Allen, Shelley; Blake, James F.; Bowcut, Vickie; Briere, David M.; Calinisan, Andrew; Dahlke, Joshua R.; Fell, Jay B.; Fischer, John P.; Gunn, Robin J.; Hallin, Jill; Laguer, Jade; Lawson, J. David; Medwid, James; Newhouse, Brad; Phong Nguyen; O'Leary, Jacob M.; Olson, Peter; Pajk, Spencer; Rahbaek, Lisa; Rodriguez, Mareli; Smith, Christopher R.; Tang, Tony P.; Thomas, Nicole C.; Vanderpool, Darin; Vigers, Guy P.; Christensen, James G.; Marx, Matthew A.
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients

KRASG12C抑制剂MRTX849为小鼠模型和患者中KRAS突变癌症的治疗易感性提供了见解

CANCER DISCOVERY
IF33.3
2020-01-09702
OAAI
Hallin, Jill; Engstrom, Lars D.; Hargis, Lauren; Calinisan, Andrew; Aranda, Ruth; Briere, David M.; Sudhakar, Niranjan; Bowcut, Vickie; Baer, Brian R.; Ballard, Joshua A.; Burkard, Michael R.; Fell, Jay B.; Fischer, John P.; Vigers, Guy P.; Xue, Yaohua; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Velastagui, Karen; Chao, Richard C.; Barton, Jeremy; Pierobon, Mariaelena; Baldelli, Elisa; Patricoin, Emanuel F., III; Cassidy, Douglas P.; Marx, Matthew A.; Rybkin, Igor I.; Johnson, Melissa L.; Ou, Sai-Hong Ignatius; Lito, Piro; Papadopoulos, Kyriakos P.; Janne, Pasi A.; Olson, Peter; Christensen, James G.
The identification of MRTX849, a novel KRASG12C inhibitor under clinical investigation, provides insight toward therapeutic susceptibility of KRAS mutant cancers
MOLECULAR CANCER THERAPEUTICS
IF5.5
2019-12-013
PRE
Christensen, James G.; Fell, Jay B.; Hallin, Jill; Baer, Brian; Engstrom, Lars; Blake, James; Briere, David; Ballard, Josh; Burkhard, Michael; Fischer, John; Vigers, Guy; Aranda, Ruth; Bowcut, Vickie; Calinisan, Andrew; Hargis, Lauren; Sudhakar, Niranjan; Marx, Matt; Olson, Peter

研究方向

暂未获取到该数据
D
David M. Briere
H 指数:17论文数:193被引数:4,449
J
James G. Christensen
H 指数:86论文数:984被引数:4.5万
P
Peter Olson
H 指数:45论文数:289被引数:1.5万
J
Jill Hallin
H 指数:22论文数:338被引数:5,333
L
Lars D. Engstrom
H 指数:17论文数:169被引数:4,288
M
Matthew A. Marx
H 指数:24论文数:159被引数:4,676
R
Ruth Aranda
H 指数:10论文数:96被引数:2,114
N
Niranjan Sudhakar
H 指数:10论文数:101被引数:2,477
L
Lauren Hargis
H 指数:6论文数:35被引数:1,968
A
Allan Hebbert
H 指数:2论文数:75被引数:208