未登录 Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4) demonstrates durable clinical responses by inducing broad immune engagement with anti-tumor activity McAlpine, Cheryl; Isabelle, Martin; Broad, Robyn; Naidoo, Revashnee; Liddle, Ashley; Duperret, Elizabeth; Noto, Paul; Wang, Ruoxi; Batrakou, Dzmitry; Middha, Sumit; Evans, Chris 分享 收藏
Defining Novel DNA Virus-Tumor Associations and Genomic Correlates Using Prospective Clinical Tumor/Normal Matched Sequencing Data Vanderbilt, Chad M.; Bowman, Anita S.; Middha, Sumit; Petrova-Drus, Kseniya; Tang, Yi-Wei; Chen, Xin; Wang, Youxiang; Chang, Jason; Rekhtman, Natasha; Busam, Klaus J.; Gupta, Sounak; Hameed, Meera; Arcila, Maria E.; Ladanyi, Marc; Berger, Michael F.; Dogan, Snjezana; Zehir, Ahmet 分享 收藏
Clinical Experience of Cerebrospinal Fluid-Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling Bale, Tejus A.; Yang, Soo-Ryum; Solomon, James P.; Nafa, Khedoudja; Middha, Sumit; Casanova, Jacklyn; Sadowska, Justyna; Skakodub, Anna; Ahmad, Hamza; Yu, Helena A.; Riely, Greg J.; Kris, Mark G.; Chandarlapaty, Sarat; Rosenblum, Marc K.; Gavrilovic, Igor; Karajannis, Matthias A.; Pentsova, Elena; Miller, Alexandra; Boire, Adrienne; Mellinghoff, Ingo; Berger, Michael F.; Zehir, Ahmet; Ladanyi, Marc; Benayed, Ryma; Arcila, Maria E. 分享 收藏
A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing Gupta, Sounak; Vanderbilt, Chad M.; Lin, Yun-Te; Benhamida, Jamal K.; Jungbluth, Achim A.; Rana, Satshil; Momeni-Boroujeni, Amir; Chang, Jason C.; Mcfarlane, Tiffany; Salazar, Paulo; Mullaney, Kerry; Middha, Sumit; Zehir, Ahmet; Gopalan, Anuradha; Bale, Tejus A.; Ganly, Ian; Arcila, Maria E.; Benayed, Ryma; Berger, Michael F.; Ladanyi, Marc; Dogan, Snjezana 分享 收藏
Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes Hechtman, Jaclyn F.; Rana, Satshil; Middha, Sumit; Stadler, Zsofia K.; Latham, Alicia; Benayed, Ryma; Soslow, Robert; Ladanyi, Marc; Yaeger, Rona; Zehir, Ahmet; Shia, Jinru 分享 收藏
Dissecting the role of zygosity and lineage in Lynch Syndrome-associated microsatellite Instability Srinivasan, Preethi; Bandlamudi, Chaitanya; Shia, Jinru; Latham, Alicia S.; Jonsson, Philip; Penson, Alexander; Middha, Sumit; Hechtman, Jackie; Zehir, Ahmet; Richards, Allison; Chawan, Shweta; Kemel, Yelena; Mandelker, Diana; Zhang, Liying; Hyman, David; Ladanyi, Marc; Robson, Mark; Offit, Kenneth; Solit, David; Taylor, Barry; Berger, Michael; Stadler, Zsofia 分享 收藏
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Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions Cocco, Emiliano; Benhamida, Jamal; Middha, Sumit; Zehir, Ahmet; Mullaney, Kerry; Shia, Jinru; Yaeger, Rona; Zhang, Liying; Wong, Donna; Villafania, Liliana; Nafa, Khedoudja; Scaltriti, Maurizio; Drilon, Alexander; Saltz, Leonard; Schram, Alison M.; Stadler, Zsofia K.; Hyman, David M.; Benayed, Ryma; Ladanyi, Marc; Hechtman, Jaclyn F. 分享 收藏
Outcome and molecular characteristics of non-invasive encapsulated follicular variant of papillary thyroid carcinoma with oncocytic features 具有嗜酸细胞特征的非侵袭性包裹性滤泡型甲状腺乳头状癌的预后和分子特征 Xu, Bin; Reznik, Ed; Tuttle, R. Michael; Knauf, Jeffrey; Fagin, James A.; Katabi, Nora; Dogan, Snjezana; Aleynick, Nathaniel; Seshan, Venkatraman; Middha, Sumit; Enepekides, Danny; Casadei, Gian Piero; Solaroli, Erica; Tallini, Giovanni; Ghossein, Ronald; Ganly, Ian 分享 收藏
Detecting MSI in plasma: Implications for early detection of lynch associated tumors Srinivasan, Preethi; Tran, Christina; Reichel, Jonathan; Patel, Juber Ahamad; Hasan, Maysun; Meng, Fanli; Jing, Xiaohong; Middha, Sumit; Zehir, Ahmet; Yaeger, Rona D.; Reidy, Diane; Tsui, Dana; Stadler, Zsofia; Berger, Michael F. 分享 收藏
YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics Fan, Pang-Dian; Narzisi, Giuseppe; Jayaprakash, Anitha D.; Venturini, Elisa; Robine, Nicolas; Smibert, Peter; Germer, Soren; Yu, Helena A.; Jordan, Emmet J.; Paik, Paul K.; Janjigian, Yelena Y.; Chaft, Jamie E.; Wang, Lu; Jungbluth, Achim A.; Middha, Sumit; Spraggon, Lee; Qiao, Huan; Lovly, Christine M.; Kris, Mark G.; Riely, Gregory J.; Politi, Katerina; Varmus, Harold; Ladanyi, Marc 分享 收藏
Gene Expression Signatures Characterized by Longitudinal Stability and Interindividual Variability Delineate Baseline Phenotypic Groups with Distinct Responses to Immune Stimulation Scheid, Adam D.; Van Keulen, Virginia P.; Felts, Sara J.; Neier, Steven C.; Middha, Sumit; Nair, Asha A.; Techentin, Robert W.; Gilbert, Barry K.; Jen, Jin; Neuhauser, Claudia; Zhang, Yuji; Pease, Larry R. 分享 收藏
Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer Janjigian, Yelena Y.; Sanchez-Vega, Francisco; Jonsson, Philip; Chatila, Walid K.; Hechtman, Jaclyn F.; Ku, Geoffrey Y.; Riches, Jamie C.; Tuvy, Yaelle; Kundra, Ritika; Bouvier, Nancy; Vakiani, Efsevia; Gao, Jianjiong; Heins, Zachary J.; Gross, Benjamin E.; Kelsen, David P.; Zhang, Liying; Strong, Vivian E.; Schattner, Mark; Gerdes, Hans; Coit, Daniel G.; Bains, Manjit; Stadler, Zsofia K.; Rusch, Valerie W.; Jones, David R.; Molena, Daniela; Shia, Jinru; Robson, Mark E.; Capanu, Marinela; Middha, Sumit; Zehir, Ahmet; Hyman, David M.; Scaltriti, Maurizio; Ladanyi, Marc; Rosen, Neal; Ilson, David H.; Berger, Michael F.; Tang, Laura; Taylor, Barry S.; Solit, David B.; Schultz, Nikolaus 分享 收藏
A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms FISH测定法可有效筛选胰腺腺泡型肿瘤中的BRAF基因重排 Wang, Lu; Basturk, Olca; Wang, Jiajing; Benayed, Ryma; Middha, Sumit; Zehir, Ahmet; Linkov, Irina; Rao, Mamta; Aryeequaye, Ruth; Cao, Long; Chmielecki, Juliann; Ross, Jeffrey; Stephens, Philip J.; Adsay, Volkan; Askan, Gokce; Balci, Serdar; Klimstra, David S. 分享 收藏
Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence Ibrahimpasic, Tihana; Xu, Bin; Landa, Inigo; Dogan, Snjezana; Middha, Sumit; Seshan, Venkatraman; Deraje, Shyam; Carlson, Diane L.; Migliacci, Jocelyn; Knauf, Jeffrey A.; Untch, Brian; Berger, Michael F.; Morris, Luc; Tuttle, R. Michael; Chan, Timothy; Fagin, James A.; Ghossein, Ronald; Ganly, Ian 分享 收藏
The genetic landscape of endometrial clear cell carcinomas DeLair, Deborah F.; Burke, Kathleen A.; Selenica, Pier; Lim, Raymond S.; Scott, Sasinya N.; Middha, Sumit; Mohanty, Abhinita S.; Cheng, Donavan T.; Berger, Michael F.; Soslow, Robert A.; Weigelt, Britta 分享 收藏
Integrative genomics analysis of metastatic colorectal cancer Lipsyc, Marla; Chatila, Walid; Hechtman, Jaclyn F.; Sanchez-Vega, Francisco; Middha, Sumit; Cercek, Andrea; Stadler, Zsofia; Kundra, Ritika; Syed, Aijazuddin; Hyman, David M.; Zehir, Ahmet; Shahrokni, Armin; Varghese, Anna; Reidy, Diane; Segal, Neil H.; Vakiani, Efsevia; Solit, David B.; Ladanyi, Marc; Berger, Michael F.; Kemeny, Nancy; Saltz, Leonard; Schultz, Nikolaus; Yaeger, Rona 分享 收藏
Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival Ptashkin, Ryan N.; Pagan, Carlos; Yaeger, Rona; Middha, Sumit; Shia, Jinru; O'Rourke, Kevin P.; Berger, Michael F.; Wang, Lu; Cimera, Robert; Wang, Jiajing; Klimstra, David S.; Saltz, Leonard; Ladanyi, Marc; Zehir, Ahmet; Hechtman, Jaclyn F. 分享 收藏
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients 从10,000例患者的前瞻性临床测序中揭示了转移性癌症的突变景观 Zehir, Ahmet; Benayed, Ryma; Shah, Ronak H.; Syed, Aijazuddin; Middha, Sumit; Kim, Hyunjae R.; Srinivasan, Preethi; Gao, Jianjiong; Chakravarty, Debyani; Devlin, Sean M.; Hellmann, Matthew D.; Barron, David A.; Schram, Alison M.; Hameed, Meera; Dogan, Snjezana; Ross, Dara S.; Hechtman, Jaclyn F.; DeLair, Deborah F.; Yao, JinJuan; Mandelker, Diana L.; Cheng, Donavan T.; Chandramohan, Raghu; Mohanty, Abhinita S.; Ptashkin, Ryan N.; Jayakumaran, Gowtham; Prasad, Meera; Syed, Mustafa H.; Rema, Anoop Balakrishnan; Liu, Zhen Y.; Nafa, Khedoudja; Borsu, Laetitia; Sadowska, Justyna; Casanova, Jacklyn; Bacares, Ruben; Kiecka, Iwona J.; Razumova, Anna; Son, Julie B.; Stewart, Lisa; Baldi, Tessara; Mullaney, Kerry A.; Al-Ahmadie, Hikmat; Vakiani, Efsevia; Abeshouse, Adam A.; Penson, Alexander V.; Jonsson, Philip; Camacho, Niedzica; Chang, Matthew T.; Won, Helen H.; Gross, Benjamin E.; Kundra, Ritika; Heins, Zachary J.; Chen, Hsiao-Wei; Phillips, Sarah; Zhang, Hongxin; Wang, Jiaojiao; Ochoa, Angelica; Wills, Jonathan; Eubank, Michael; Thomas, Stacy B.; Gardos, Stuart M.; Reales, Dalicia N.; Galle, Jesse; Durany, Robert; Cambria, Roy; Abida, Wassim; Cercek, Andrea; Feldman, Darren R.; Gounder, Mrinal M.; Hakimi, A. Ari; Harding, James J.; Iyer, Gopa; Janjigian, Yelena Y.; Jordan, Emmet J.; Kelly, Ciara M.; Lowery, Maeve A.; Morris, Luc G. T.; Omuro, Antonio M.; Raj, Nitya; Razavi, Pedram; Shoushtari, Alexander N.; Shukla, Neerav; Soumerai, Tara E.; Varghese, Anna M.; Yaeger, Rona; Coleman, Jonathan; Bochner, Bernard; Riely, Gregory J.; Saltz, Leonard B.; Scher, Howard I.; Sabbatini, Paul J.; Robson, Mark E.; Klimstra, David S.; Taylor, Barry S.; Baselga, Jose; Schultz, Nikolaus; Hyman, David M.; Arcila, Maria E.; Solit, David B.; Ladanyi, Marc; Berger, Michael F. 分享 收藏
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications 癌症基因组图谱中结直肠癌的形态学特征揭示了不同的形态学-分子关联: 临床和生物学意义 Shia, Jinru; Schultz, Nikolaus; Kuk, Deborah; Vakiani, Efsevia; Middha, Sumit; Segal, Neil H.; Hechtman, Jaclyn F.; Berger, Michael F.; Stadler, Zsofia K.; Weiser, Martin R.; Wolchok, Jedd D.; Boland, C. Richard; Gonen, Mithat; Klimstra, David S. 分享 收藏
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