Subbiah, Vivek; Yu, Peter P.; Sarangarajan, Rangaprasad; Kiebish, Michael A.; Rodrigues, Leonardo O.; Miller, Gregory M.; Akmaev, Viatcheslav R.; Luan, Shen; McCook, John P.; Tanna, Nikunj; Reilly, Tracey; Chen, Emily; Bussberg, Valerie; Ravipaty, Shobha; Vishnudas, Vivek K.; Gesta, Stephane; Lucius, David; Bruce, Can; Hazarika, Suwagmani; Lyng, Arianne; Klotz, Allison; Tolstikov, Vladimir; Stevens, Janice; Chua, Victoria S.; Granger, Elder; Tekumalla, Poornima K.; Benaim, Ely; Modur, Vijay; Rudoltz, Marc S.; Song, Paul Y.; Tagawa, Scott T.; Hendifer, Andrew; Chawla, Sant P.; Shah, Manish A.; Hong, David S.; Zinner, Ralph; Narain, Niven R.; Kundranda, Madappa N.

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

12-脂氧合酶通过从棕色脂肪产生ω-3脂质12-HEPE来调节冷适应和葡萄糖代谢

Cell Metabolism

IF30.9

2025-11-050

PRE

BPM31510 engagement of the Warburg effect in GBM to therapeutically modulate tumor metabolism through ROS mediated processes preclinically and clinically

BPM31510通过Warburg效应在GBM中的参与，以在临床前和临床阶段通过ROS介导的过程治疗性调控肿瘤代谢。

NEURO-ONCOLOGY

IF13.4

2025-11-010

OAAI

A novel therapeutic strategy using a single non-toxic agent that produces consistent long-term control of orthotopic experimental glioblastomas

一种使用单一非毒性制剂的新型治疗策略，可实现对正位实验性胶质母细胞瘤的持续长期控制

NEURO-ONCOLOGY

IF13.4

2025-11-010

OAAI

A study of RNA splicing and protein expression in the living human brain

对活体人脑中RNA剪接和蛋白质表达的研究

PLOS ONE

IF2.6

2025-10-090

PRE

Kopell, Brian H.; Kaji, Deepak A.; Liharska, Lora E.; Vornholt, Eric; Lund, Anina; Hashemi, Alice; Thompson, Ryan C.; Johnson, Jessica S.; Bussola, Nicole; Cheng, Esther; Park, You Jeong; Shah, Punit; Ma, Weiping; Searfoss, Richard; Miller, Gregory M.; Chand, Nischal Mahaveer; Humphrey, Jack; Wilkins, Lillian; Ziafat, Kimia; Silk, Hannah; Linares, Lisa M.; Sullivan, Brendan; Feng, Claudia; Cohen, Vanessa; Kota, Prashant; Moya, Emily; Rieder, Marysia-Kolbe; Nadkarni, Girish N.; Breen, Michael S.; Scarpa, Joseph; Narain, Niven R.; Wang, Pei; Kiebish, Michael A.; Schadt, Eric E.; Beckmann, Noam D.; Charney, Alexander W.

12,13-diHOME protects against the age-related decline in cardiovascular function via attenuation of CaMKII

12,13-二羟基十八碳三烯酸通过减轻钙调素依赖性蛋白激酶II对与年龄相关的心血管功能下降具有保护作用

Nature Communications

IF15.7

2025-08-020

Shinsuke Nirengi; Benjamin Buck; Devleena Das; Carmem Peres Valgas da Silva; Jazmin Calyeca; Lisa A. Baer; Hsiang-Ling Huang; Pablo Vidal; Revati S. Dewal; Kelsey M. Pinckard; Elisa Félix-Soriano; Diego Hernandez-Saavedra; Andrew Gerea; Kavya Dathathreya; Silvia Duarte-Sanmiguel; Ty A. Saldana; Harrison L. Hookfin; Matthew W. Gorr; Valerie Bussberg; Juan J. Aristizabal-Henao; Michael A. Kiebish; Roeland J. W. Middelbeek; Laurie J. Goodyear; Paul M. Coen; Krishna Chinthalapudi; Loren E. Wold; Ana L. Mora; Thomas J. Hund; Daniel Gallego-Perez; Kristin I. Stanford

The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

瓦堡假说与线粒体肿瘤代谢理论的出现

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

IF3

2025-04-080

OAAI

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

胶质母细胞瘤生酮代谢治疗的临床研究框架建议

BMC MEDICINE

IF8.3

2024-12-050

OAAI

Duraj, Tomas; Kalamian, Miriam; Zuccoli, Giulio; Maroon, Joseph C.; D'Agostino, Dominic P.; Scheck, Adrienne C.; Poff, Angela; Winter, Sebastian F.; Hu, Jethro; Klement, Rainer J.; Hickson, Alicia; Lee, Derek C.; Cooper, Isabella; Kofler, Barbara; Schwartz, Kenneth A.; Phillips, Matthew C. L.; Champ, Colin E.; Zupec-Kania, Beth; Tan-Shalaby, Jocelyn; Serfaty, Fabiano M.; Omene, Egiroh; Arismendi-Morillo, Gabriel; Kiebish, Michael; Cheng, Richard; El-Sakka, Ahmed M.; Pflueger, Axel; Mathews, Edward H.; Worden, Donese; Shi, Hanping; Cincione, Raffaele Ivan; Spinosa, Jean Pierre; Slocum, Abdul Kadir; Iyikesici, Mehmet Salih; Yanagisawa, Atsuo; Pilkington, Geoffrey J.; Chaffee, Anthony; Abdel-Hadi, Wafaa; Elsamman, Amr K.; Klein, Pavel; Hagihara, Keisuke; Clemens, Zsofia; Yu, George W.; Evangeliou, Athanasios E.; Nathan, Janak K.; Smith, Kris; Fortin, David; Dietrich, Jorg; Mukherjee, Purna; Seyfried, Thomas N.

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells

ASN NEURO

IF3.7

2024-12-023

OAAI

IMPROVED ANTI-GLIOBLASTOMA EFFICACY BY BRG399, A NOVEL ORAL MICROTUBULE BINDING AGENT

NEURO-ONCOLOGY

IF13.4

2024-11-110

PRE

A phase II study of BPM31510 (a lipid nanodispersion of oxidized CoQ10) with vitamin K in combination with standard of care (SOC) RT and TMZ in glioblastoma multiforme (GBM) patients without prior therapy

一项关于BPM31510（氧化辅酶Q10的脂质纳米分散体）联合维生素K，与标准护理（SOC）放疗（RT）和替莫唑胺（TMZ）联用治疗未经先前治疗的胶质母细胞瘤（GBM）患者的II期研究