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N

Niven R. Narain

bpgbio
H指数:32
被引数:4,383

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BPM31510 Increases the CoQ Pool in Chemically Induced CoQ-Deficient Cells, CoQ-Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues

BPM31510 在化学诱导的CoQ缺乏细胞、CoQ缺乏患者成纤维细胞以及代谢活跃的小鼠组织中增加CoQ池

the faseb journal
IF0
2026-04-030
OA
Juan J. Aristizabal-Henao; Sarah R. Wessel; Sylwia A. Stopka; Srada Karmacharya; Devon Van Cura; Alba Pesini; Kelsey R. Nickerson; Kashni Grover; Oksana Zavidij; Archna Ravi; Andressa L. Mota; Kenneth M. Rosen; Maria-Dorothea Nastke; Megan K. Cox; Niven R. Narain; Vijay Modur; Catarina M. Quinzii; Stephane Gesta; Michael A. Kiebish
Author Correction: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

作者更正：冷诱导的脂酮酸12,13-diHOME促进脂肪酸转运进入棕色脂肪组织

Nature Medicine
IF50
2026-01-020
PRE
Matthew D Lynes; Luiz O Leiria; Morten Lundh; Alexander Bartelt; Farnaz Shamsi; Tian Lian Huang; Hirokazu Takahashi; Michael F Hirshman; Christian Schlein; Alexandra Lee; Lisa A Baer; Francis J May; Fei Gao; Niven R Narain; Emily Y Chen; Michael A Kiebish; Aaron M Cypess; Matthias Blüher; Laurie J Goodyear; Gökhan S Hotamisligil; Kristin I Stanford; Yu-Hua Tseng
Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients

Ia/b期多中心研究：BPM31510IV单药治疗和联合化疗在实体瘤患者中靶向线粒体代谢/瓦伯格效应的应用

Cancer Research Communications
IF0
2025-12-010
OA
Subbiah, Vivek; Yu, Peter P.; Sarangarajan, Rangaprasad; Kiebish, Michael A.; Rodrigues, Leonardo O.; Miller, Gregory M.; Akmaev, Viatcheslav R.; Luan, Shen; McCook, John P.; Tanna, Nikunj; Reilly, Tracey; Chen, Emily; Bussberg, Valerie; Ravipaty, Shobha; Vishnudas, Vivek K.; Gesta, Stephane; Lucius, David; Bruce, Can; Hazarika, Suwagmani; Lyng, Arianne; Klotz, Allison; Tolstikov, Vladimir; Stevens, Janice; Chua, Victoria S.; Granger, Elder; Tekumalla, Poornima K.; Benaim, Ely; Modur, Vijay; Rudoltz, Marc S.; Song, Paul Y.; Tagawa, Scott T.; Hendifer, Andrew; Chawla, Sant P.; Shah, Manish A.; Hong, David S.; Zinner, Ralph; Narain, Niven R.; Kundranda, Madappa N.
12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

12-脂氧合酶通过从棕色脂肪产生ω-3脂质12-HEPE来调节冷适应和葡萄糖代谢

Cell Metabolism
IF30.9
2025-11-050
PRE
Luiz Osório Leiria; Chih-Hao Wang; Matthew D. Lynes; Kunyan Yang; Farnaz Shamsi; Mari Sato; Satoru Sugimoto; Emily Y. Chen; Valerie Bussberg; Niven R. Narain; Brian E. Sansbury; Justin Darcy; Tian Lian Huang; Sean D. Kodani; Masaji Sakaguchi; Andréa L. Rocha; Tim J. Schulz; Alexander Bartelt; Gökhan S. Hotamisligil; Michael F. Hirshman; Klaus van Leyen; Laurie J. Goodyear; Matthias Blüher; Aaron M. Cypess; Michael A. Kiebish; Matthew Spite; Yu-Hua Tseng
BPM31510 engagement of the Warburg effect in GBM to therapeutically modulate tumor metabolism through ROS mediated processes preclinically and clinically

BPM31510通过Warburg效应在GBM中的参与，以在临床前和临床阶段通过ROS介导的过程治疗性调控肿瘤代谢。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Kiebish, Michael; Modur, Vijay; Stockdale, Brian; Zavidij, Oksana; Gesta, Stephane; Nie, Bing; Chand, Nischal Mahaveer; Miller, Greg; Aristizabal-Henao, Juan; Narain, Niven; Recht, Lawrence; Nagpal, Seema
Trial in Progress (TiP): Interim analysis of a Phase 2 study of BPM31510 (a lipid nanodispersion of oxidized CoQ10) with Vitamin K in combination with Standard of Care (SOC) RT and TMZ in Glioblastoma Multiforme (GBM) patients without prior therapy

进行中试验（TiP）：一项关于BPM31510（氧化辅酶Q10的脂质纳米分散体）联合维生素K，与标准护理（SOC）放疗（RT）和替莫唑胺（TMZ）联用治疗未经前期治疗的胶质母细胞瘤（GBM）患者的II期研究的期中分析

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Nagpal, Seema; Stockdale, Brian; Cohen, Adam; Patil, Chirag; Vaillant, Brian; Elmore, Kevin; Brenner, Andrew; Juthani, Rupa; Reardon, David; Kendle, Ryan; Spira, Alexander; Wykretowicz, Jedrzej; Zhukova-Harrill, Valentina; Nie, Bing; Narain, Niven; Modur, Vijay
A study of RNA splicing and protein expression in the living human brain

对活体人脑中RNA剪接和蛋白质表达的研究

PLOS ONE
IF2.6
2025-10-090
PRE
Kopell, Brian H.; Kaji, Deepak A.; Liharska, Lora E.; Vornholt, Eric; Lund, Anina; Hashemi, Alice; Thompson, Ryan C.; Johnson, Jessica S.; Bussola, Nicole; Cheng, Esther; Park, You Jeong; Shah, Punit; Ma, Weiping; Searfoss, Richard; Miller, Gregory M.; Chand, Nischal Mahaveer; Humphrey, Jack; Wilkins, Lillian; Ziafat, Kimia; Silk, Hannah; Linares, Lisa M.; Sullivan, Brendan; Feng, Claudia; Cohen, Vanessa; Kota, Prashant; Moya, Emily; Rieder, Marysia-Kolbe; Nadkarni, Girish N.; Breen, Michael S.; Scarpa, Joseph; Narain, Niven R.; Wang, Pei; Kiebish, Michael A.; Schadt, Eric E.; Beckmann, Noam D.; Charney, Alexander W.
A phase II study of BPM31510 (a lipid nanodispersion of oxidized CoQ10) with vitamin K in combination with standard of care (SOC) RT and TMZ in glioblastoma multiforme (GBM) patients without prior therapy

一项关于BPM31510（氧化辅酶Q10的脂质纳米分散体）联合维生素K，与标准护理（SOC）放疗（RT）和替莫唑胺（TMZ）联用治疗未经先前治疗的胶质母细胞瘤（GBM）患者的II期研究

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Stockdale, B.; Bertrand, S.; Villanueva, E.; Naya, L.; Lyng, A.; Berman, B.; Vishnudas, V. K.; Kiebish, M. A.; Gesta, S.; Tekumalla, P. K.; Narain, N. R.; Recht, L.; Modur, V.; Nagpal, S.
Identification and validation of N-acetylputrescine in combination with non-canonical clinical features as a Parkinson's disease biomarker panel
SCIENTIFIC REPORTS
IF3.9
2024-05-022
OAAI
Peng, Kuan-Wei; Klotz, Allison; Guven, Arcan; Kapadnis, Unnati; Ravipaty, Shobha; Tolstikov, Vladimir; Vemulapalli, Vijetha; Rodrigues, Leonardo O.; Li, Hongyan; Kellogg, Mark D.; Kausar, Farah; Rees, Linda; Sarangarajan, Rangaprasad; Schuele, Birgitt; Langston, William; Narain, Paula; Narain, Niven R.; Kiebish, Michael A.
Diagnostic assessment of Filamin A ( FLNA) as a serum biomarker for identification of benign prostatic hyperplasia vs aggressive prostate cancer in a prospective Mexican cohort
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Rodriguez, Arturo; Mendoza, Arturo; Rosenburg, Matthew; Castaneda, Jose de J.; Melgar, Alejandro A.; Ciseros, Bernardo; Gangemi, Adrian G.; Chand, Nischal M.; Tekumalla, Poornima; Miller, Greg; Thakurta, Anjan; Banuelos, Diego; Real, Juan J.; Joya, Diego A.; Romero, Alejandro; Farias, Juan D.; Cabeza, Eduardo; Remess, Hector H.; Delgado, Julio J.; Sanchez, Hector M.; Barragan, Ignacio; Rodriguez, Mabel; Garcia, Barbara; Sanchez, David A.; Izquierdo, Juan; Lopez, Elizabeth M.; Hanao, Juan; Frusch, Jeronimo G.; Narain, Niven R.; Kiebish, Michael A.
Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia
SCIENTIFIC REPORTS
IF3.9
2024-01-196
OAAI
Ravasz, Dora; Bui, David; Nazarian, Sara; Pallag, Gergely; Karnok, Noemi; Roberts, Jennie; Marzullo, Bryan P.; Tennant, Daniel A.; Greenwood, Bennett; Kitayev, Alex; Hill, Collin; Komlodi, Timea; Doerrier, Carolina; Cunatova, Kristyna; Fernandez-Vizarra, Erika; Gnaiger, Erich; Kiebish, Michael A.; Raska, Alexandra; Kolev, Krasimir; Czumbel, Bence; Narain, Niven R.; Seyfried, Thomas N.; Chinopoulos, Christos

研究方向

暂未获取到该数据
M
Michael A. Kiebish
H 指数:41论文数:247被引数:6,625
R
Rangaprasad Sarangarajan
H 指数:27论文数:240被引数:2,176
V
Vivek K. Vishnudas
H 指数:14论文数:133被引数:622
S
Stéphane Gesta
H 指数:26论文数:129被引数:6,705
V
Vladimir Tolstikov
H 指数:36论文数:159被引数:5,665
V
Viatcheslav R. Akmaev
H 指数:21论文数:116被引数:2,854
L
Leonardo O. Rodrigues
H 指数:10论文数:81被引数:1,421
A
Anne R. Diers
H 指数:21论文数:125被引数:2,336
E
Elder Granger
H 指数:13论文数:70被引数:715
B
Bennett Greenwood
H 指数:13论文数:43被引数:926