Crispin Miller - Publications, H-index & Citations

Crispin Miller

switchback road

46H指数

202论文数

9.8K被引数

收录论文 76

发表时间

Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis Runx1和Runx2协同作用抑制Wnt/β-catenin驱动的乳腺肿瘤发生

British Journal of Cancer

IF6.8

2026-05-07

OAAI

Alessandra I. Riggio; Kerri Sweeney; Robin Shaw; Amy Lawlor; Adiba Khan; Nicola Ferrari; Jayanthi Anand; Laura CA Galbraith; Kathryn Gilroy; Courtney Bull; Alex L. Young; Dimitris Athineos; Holly Hall; Farah Ghaffar; Mark Hughes; Claire A. Mitchell; Louise Mitchell; Colin Nixon; Peter D. Adams; Edward W. Roberts; Crispin J. Miller; Philip D. Dunne; Kirsteen J. Campbell; Ewan R. Cameron; Karen Blyth

Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model Vγ1 γδ T细胞在自发性肺癌小鼠模型中引导气道巨噬细胞向促纤维化反应方向转变

Science Advances

IF12.5

2026-03-04

OAAI

Ximena L. Raffo-Iraolagoitia; Amanda J. McFarlane; Sarah Laing; Ryan Corbyn; Lindsey W. G. Arnott; Frédéric Fercoq; Lynn McGarry; Judith Secklehner; Marco De Donatis; John B. G. Mackey; Bjorn Kruspig; Robert Wiesheu; Ya-Ching Hsieh; Robin Shaw; Kai Rakovic; John Le Quesne; Graeme Clark; Colin Nixon; Crispin Miller; Kristina Kirschner; Calum C. Bain; Daniel J. Murphy; Seth B. Coffelt; Leo M. Carlin

Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation 核磷蛋白支持WNT驱动的过度增殖和肿瘤启动

Nature Genetics

IF29

2025-12-18

OAAI

Georgios Kanellos; Chiara Giacomelli; Alexander Raven; Nikola Vlahov; Hu Jin; Pauline Herviou; Sudhir B. Malla; Nadia Nasreddin; Patricia P. Centeno; Constantinos Alexandrou; Kathryn Gilroy; Rachel L. Baird; Kathryn Pennel; June Munro; Joseph A. Waldron; Holly Hall; Leah Officer-Jones; Sheila Bryson; Douglas Strathdee; Sergio Lilla; Sara Zanivan; Vivienne Morrison; Colin Nixon; Rachel A. Ridgway; Crispin Miller; John R. P. Knight; Andrew D. Campbell; Philip D. Dunne; John Le Quesne; Joanne Edwards; Peter J. Park; Martin Bushell; Owen J. Sansom

MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance MAPK驱动的上皮细胞可塑性驱动结直肠癌治疗抵抗

Nature

IF48.5

2025-11-24

PREAI

Mark White; Megan L. Mills; Laura M. Millett; Kathryn Gilroy; Yourae Hong; Lucas B. Zeiger; Rosalin J. Simpson; Shania M. Corry; Amelia Ligeza; Tamsin R. M. Lannagan; Susanti Susanti; Rachel A. Ridgway; Ayse S. Yazgili; Lucile Grzesiak; Raheleh Amirkhah; Catriona A. Ford; Nikola Vlahov; Hannah Tovell; Leah Officer-Jones; Catherine Ficken; Rachel Pennie; Arafath K. Najumudeen; Alexander Raven; Nadia Nasreddin; Ekansh Chauhan; Andrew S. Papanastasiou; Colin Nixon; Vivienne Morrison; Rene Jackstadt; Janet S. Graham; Crispin J. Miller; Sarah J. Ross; Simon T. Barry; Valeria Pavet; Richard H. Wilson; John Le Quesne; Philip D. Dunne; Sabine Tejpar; Simon Leedham; Andrew D. Campbell; Owen J. Sansom

Hepatic zonation determines tumorigenic potential of mutant β-catenin 肝区室分布决定了突变型β-catenin的致瘤潜能

Nature

IF48.5

2025-11-19

OAAI

Alexander Raven; Kathryn Gilroy; Hu Jin; Joseph A. Waldron; Holly Leslie; June Munro; Holly Hall; Rachel A. Ridgway; Catriona A. Ford; Doga C. Gulhan; Nikola Vlahov; Megan L. Mills; Andrew Hartley; Eve Anderson; Sheila Bryson; Nathalie Sphyris; Miryam Müller; Stephanie May; Barbara Cadden; Colin Nixon; Scott H. Waddell; Rachel Guest; Luke Boulter; Nick Barker; Hans Clevers; Hao Zhu; Johanna Ivaska; Douglas Strathdee; Crispin J. Miller; Nigel B. Jamieson; Martin Bushell; Peter J. Park; Thomas G. Bird; Owen J. Sansom

PLM-interact: extending protein language models to predict protein-protein interactions PLM-interact：扩展蛋白质语言模型以预测蛋白质-蛋白质相互作用

Nature Communications

IF15.7

2025-10-27

OAAI

Dan Liu; Francesca Young; Kieran D. Lamb; Adalberto Claudio Quiros; Alexandrina Pancheva; Crispin J. Miller; Craig Macdonald; David L. Robertson; Ke Yuan

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)

NATURE GENETICS

IF31.8

2024-06-03

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors

EMBO JOURNAL

IF8.3

2024-05-30

OAAI

Wiesheu, Robert; Edwards, Sarah C.; Hedley, Ann; Hall, Holly; Tosolini, Marie; da Silva, Marcelo Gregorio Filho Fares; Sumaria, Nital; Castenmiller, Suzanne M.; Wardak, Leyma; Optaczy, Yasmin; Lynn, Amy; Hill, David G.; Hayes, Alan J.; Hay, Jodie; Kilbey, Anna; Shaw, Robin; Whyte, Declan; Walsh, Peter J.; Michie, Alison M.; Graham, Gerard J.; Manoharan, Anand; Halsey, Christina; Blyth, Karen; Wolkers, Monika C.; Miller, Crispin; Pennington, Daniel J.; Jones, Gareth W.; Fournie, Jean-Jacques; Bekiaris, Vasileios; Coffelt, Seth B.

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

NATURE GENETICS

IF31.8

2024-02-13

OAAI

Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.

An update regarding the Meso-ORIGINS study: part of the PREDICT-Meso International Accelerator

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Neilly, Mark; Tsim, Selina; Maclay, John; Bilancia, Rocco; Bibby, Anna; Gatheral, Timothy; Ionescu, Alina; Griffiths, Andrew; Aujayeb, Avinash; Rahman, Najib; Fallon, Janet; Craig, Christopher; Macdougall, Michelle; Corcoran, John; Panchal, Rakesh; Chetty, Mahendran; Lamote, Kevin; Cowell, Gordon; Miller, Crispin; Rintoul, Robert; Van Meerbeeck, Jan; Roche, Joshua; Macpherson, Alexandrea; Alexander, Laura; Roberts, Julie; Gourlay, Jacqui; Mcgarry, Joanne; Walker, Nicola; Blyth, Kevin

PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer

EMBO JOURNAL

IF8.3

2023-08-14

OAAI

Nikolatou, Konstantina; Sandilands, Emma; Roman-Fernandez, Alvaro; Cumming, Erin M.; Freckmann, Eva; Lilla, Sergio; Buetow, Lori; McGarry, Lynn; Neilson, Matthew; Shaw, Robin; Strachan, David; Miller, Crispin; Huang, Danny T.; McNeish, Iain A.; Norman, James C.; Zanivan, Sara; Bryant, David M.

Hypoxia-mediated down-regulation of bid and bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

401

OAAI

Erler, JT; Cawthorne, CJ; Williams, KJ; Koritzinsky, M; Wouters, BG; Wilson, C; Miller, C; Demonacos, C; Stratford, IJ; Dive, C

Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function

SCIENCE ADVANCES

IF12.5

2023-02-03

OAAI

Roman-Fernandez, Alvaro; Mansour, Mohammed A.; Kugeratski, Fernanda G.; Anand, Jayanthi; Sandilands, Emma; Galbraith, Laura; Rakovic, Kai; Freckmann, Eva C.; Cumming, Erin M.; Park, Ji; Nikolatou, Konstantina; Lilla, Sergio; Shaw, Robin; Strachan, David; Mason, Susan; Patel, Rachana; McGarry, Lynn; Katoch, Archana; Campbell, Kirsteen J.; Nixon, Colin; Miller, Crispin J.; Leung, Hing Y.; Le Quesne, John; Norman, James C.; Zanivan, Sara; Blyth, Karen; Bryant, David M.

PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing γδ T cells

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2022-12-07

OAAI

Edwards, Sarah C.; Hedley, Ann; Hoevenaar, Wilma H. M.; Wiesheu, Robert; Glauner, Teresa; Kilbey, Anna; Shaw, Robin; Boufea, Katerina; Batada, Nizar; Hatano, Shinya; Yoshikai, Yasunobu; Blyth, Karen; Miller, Crispin; Kirschner, Kristina; Coffelt, Seth B.

Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging Traject3d允许通过实时成像在3D培养物中无标记鉴定不同的共现表型

NATURE COMMUNICATIONS

IF15.7

2022-09-09

OAAI

Freckmann, Eva C.; Sandilands, Emma; Cumming, Erin; Neilson, Matthew; Roman-Fernandez, Alvaro; Nikolatou, Konstantina; Nacke, Marisa; Lannagan, Tamsin R. M.; Hedley, Ann; Strachan, David; Salji, Mark; Morton, Jennifer P.; McGarry, Lynn; Leung, Hing Y.; Sansom, Owen J.; Miller, Crispin J.; Bryant, David M.

Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix (vol 4, pg 639, 2022)

NATURE METABOLISM

IF20.8

2022-08-04

OAAI

Kay, Emily J.; Paterson, Karla; Riera-Domingo, Carla; Sumpton, David; Dabritz, J. Henry M.; Tardito, Saverio; Boldrini, Claudia; Hernandez-Fernaud, Juan R.; Athineos, Dimitris; Dhayade, Sandeep; Stepanova, Ekaterina; Gjerga, Enio; Neilson, Lisa J.; Lilla, Sergio; Hedley, Ann; Koulouras, Grigorios; McGregor, Grace; Jamieson, Craig; Johnson, Radia Marie; Park, Morag; Kirschner, Kristina; Miller, Crispin; Kamphorst, Jurre J.; Loayza-Puch, Fabricio; Saez-Rodriguez, Julio; Mazzone, Massimiliano; Blyth, Karen; Zagnoni, Michele; Zanivan, Sara

Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix 癌症相关的成纤维细胞需要PYCR1合成脯氨酸以沉积促肿瘤发生的细胞外基质

NATURE METABOLISM

IF20.8

2022-06-27

OAAI

Kay, Emily J.; Paterson, Karla; Riero-Domingo, Carla; Sumpton, David; Dabritz, J. Henry M.; Tardito, Saverio; Boldrini, Claudia; Hernandez-Fernaud, Juan R.; Athineos, Dimitris; Dhayade, Sandeep; Stepanova, Ekaterina; Gjerga, Enio; Neilson, Lisa J.; Lilla, Sergio; Hedley, Ann; Koulouras, Grigorios; McGregor, Grace; Jamieson, Craig; Johnson, Radia Marie; Park, Morag; Kirschner, Kristina; Miller, Crispin; Kamphorst, Jurre J.; Loayza-Puch, Fabricio; Saez-Rodriguez, Julio; Mazzone, Massimiliano; Blyth, Karen; Zagnoni, Michele; Zanivan, Sara

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse (vol 25, pg 1534, 2019)肿瘤切除和疾病复发前的肺静脉循环肿瘤细胞播散 (第25卷，1534页，2019)

NATURE MEDICINE

IF50

2020-06-03

OAAI

Chemi, Francesca; Rothwell, Dominic G.; McGranahan, Nicholas; Gulati, Sakshi; Abbosh, Chris; Pearce, Simon P.; Zhou, Cong; Wilson, Gareth A.; Jamal-Hanjani, Mariam; Birkbak, Nicolai; Pierce, Jackie; Kim, Chang Sik; Ferdous, Saba; Burt, Deborah J.; Slane-Tan, Daniel; Gomes, Fabio; Moore, David; Shah, Rajesh; Al Bakir, Maise; Hiley, Crispin; Veeriah, Selvaraju; Summers, Yvonne; Crosbie, Philip; Ward, Sophia; Mesquita, Barbara; Dynowski, Marek; Biswas, Dhruva; Tugwood, Jonathan; Blackhall, Fiona; Miller, Crispin; Hackshaw, Allan; Brady, Ged; Swanton, Charles; Dive, Caroline

Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma

ESMO OPEN

IF8.3

2020-01-01

OAAI

Lee, Rebecca Jane; Khandelwal, Garima; Baenke, Franziska; Cannistraci, Alessio; Macleod, Kenneth; Mundra, Piyushkumar; Ashton, Garry; Mandal, Amit; Viros, Amaya; Gremel, Gabriela; Galvani, Elena; Smith, Matthew; Carragher, Neil; Dhomen, Nathalie; Miller, Crispin; Lorigan, Paul; Marais, Richard

In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival (vol 74, pg 105, 2019)

SCIENTIFIC REPORTS

IF3.9

2019-12-24

OAAI

Memon, Danish; Bi, Jing; Miller, Crispin J.

研究方向