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J

Junichi Takagi

osaka university

66H指数
355论文数
1.6W被引数
收录论文 105
发表时间
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High-resolution cryo-EM structure of integrin αIIbβ3 bound to disease-causing maternal HPA-1a antibody that blocks integrin activation整合素αIIbβ3与致病性母源HPA-1a抗体结合的高分辨率冷冻电镜结构，该抗体阻断整合素激活
errScience Advances
IF12.5
err2026-07-17
err0
errOAAI
errJosé M. de Pereda; Wendy Stam; Marcos Gragera; Femke van der Meer; Francisco J. Chichón; Eleftherios Zarkadas; Ellen van der Schoot; Gestur Vidarsson; Junichi Takagi; Coert Margadant
err分享
err收藏
Functional and structural characterization of a novel anti-His-tag antibody, HisMab-1一种新型抗-His标签抗体HisMab-1的功能与结构表征
errJournal of Molecular Biology
IF4.5
err2025-12-03
err0
PREAI
errNatsuki Hitomi; Satowa Hoshi; Mika K. Kaneko; Ryuichi Kato; Kenji Iwasaki; Junichi Takagi; Yukinari Kato; Ayaka Harada-Hikita; Takao Arimori
err分享
err收藏
Muscle-specific tyrosine kinase activation by a peptide-based dimerizer is orientation dependent肽基二聚化诱导的肌肉特异性酪氨酸激酶激活具有方向依赖性
errStructure
IF4.3
err2025-11-24
err0
PREAI
errFumiya Mizutani; Kyoko Matoba; Hayden Peacock; Mitsuhiro Yamada; Emiko Mihara; Osamu Higuchi; Hiroaki Suga; Takao Arimori; Junichi Takagi
err分享
err收藏
Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacyiPSC来源的CAR T细胞通过工程化改造克服多种实体瘤疗效障碍，实现对HER2的偏好性肿瘤靶向。
errCell Stem Cell
IF20.4
err2025-06-04
err0
PREAI
errMartin P. Hosking; Soheila Shirinbak; Kyla Omilusik; Shilpi Chandra; Mika K. Kaneko; Angela Gentile; Susumu Yamamoto; Bishwas Shrestha; Joy Grant; Megan Boyett; Demetrio Cardenas; Hannah Keegan; Samad Ibitokou; Carolina Pavon; Takahiro Mizoguchi; Tatsuya Ihara; Daisuke Nakayama; Ramzey Abujarour; Tom T. Lee; Raedun Clarke; Jode Goodridge; Eigen Peralta; Tatsuo Maeda; Junichi Takagi; Takao Arimori; Yukinari Kato; Bahram Valamehr
err分享
err收藏
Engineered ACE2 decoy in dry powder form for inhalation: A novel therapy for SARS-CoV-2 variants吸入用干粉形式工程化ACE2诱饵：一种针对SARS-CoV-2变种的新型疗法
errMOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT
IF4.7
err2025-06-01
err0
errOAAI
errTakaaki Ito; Tatsuya Suzuki; Yusuke Sakai; Keisuke Nishioka; Yumi Itoh; Kentarou Sakamoto; Nariko Ikemura; Satoaki Matoba; Yasunari Kanda; Junichi Takagi; Toru Okamoto; Kohei Tahara; Atsushi Hoshino
err分享
err收藏
Immunological analysis of LC16m8 vaccine: preclinical and early clinical insights into mpoxLC16m8疫苗的免疫学分析：对猴痘的预临床和早期临床见解
errEBIOMEDICINE
IF10.8
err2025-05-01
err0
PREAI
errKobiyama, Kouji; Utsumi, Daichi; Kaku, Yu; Sasaki, Eita; Yasui, Fumihiko; Okamura, Tomotaka; Onodera, Taishi; Tobuse, Asuka Joy; Sakkour, Areej; Amiry, Ahmad Faisal; Hayashi, Tomoya; Temizoz, Burcu; Liu, Kaiwen; Negishi, Hideo; Toyama-Sorimachi, Noriko; Kohara, Michinori; Sawasaki, Tatsuya; Takagi, Junichi; Sato, Kei; Takahashi, Yoshimasa; Yasutomi, Yasuhiro; Ishii, Ken J.
err分享
err收藏
CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplantCAR T或NK细胞靶向急性髓系白血病异基因造血干细胞移植后不匹配的HLA-DR分子
errNATURE CANCER
IF28.5
err2025-03-24
err1
PREAI
errIkeda, Shunya; Hasegawa, Kana; Kogue, Yosuke; Arimori, Takao; Kawamoto, Ryuhei; Wibowo, Tansri; Yaga, Moto; Inada, Yuri; Uehara, Hirofumi; Matsubara, Miwa; Tachikawa, Mana; Suga, Makiko; Kida, Shuhei; Shibata, Kumi; Tsutsumi, Kazuhito; Fukushima, Kentaro; Fujita, Jiro; Ueda, Tomoaki; Kusakabe, Shinsuke; Hino, Akihisa; Ichii, Michiko; Hirose, Asao; Nakamae, Hirohisa; Hino, Masayuki; Nakao, Takafumi; Inoue, Megumu; Yoshihara, Kyoko; Yoshihara, Satoshi; Ueda, Shuji; Tachi, Tetsuro; Kuroda, Hideki; Murakami, Koki; Kijima, Noriyuki; Kishima, Haruhiko; Igashira, Eri; Murakami, Mari; Takiuchi, Tsuyoshi; Kimura, Tadashi; Hiroshima, Takashi; Kimura, Toru; Shintani, Yasushi; Imai, Chihaya; Yusa, Kosuke; Mori, Ryota; Ogino, Takayuki; Eguchi, Hidetoshi; Takeda, Kiyoshi; Oji, Yusuke; Kumanogoh, Atsushi; Takagi, Junichi
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err收藏
Anti-α6β4 integrin autoantibodies inhibit the binding of laminins to α6β4 integrin in patients with pemphigoid and affect the gastrointestinal tract
errJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
IF8
err2023-11-20
err2
PREAI
errArase, Noriko; Sasaoka, Yusuke; Narita, Jun; Kiyohara, Eiji; Hashimoto, Kazuhisa; Shinzaki, Shinichiro; Nojima, Satoshi; Takagi, Junichi; Fujimoto, Manabu
err分享
err收藏
Advances in tooth agenesis and tooth regeneration
errREGENERATIVE THERAPY
IF3.5
err2023-03-01
err5
errOAAI
errRavi, V.; Murashima-Suginami, A.; Kiso, H.; Tokita, Y.; Huang, C. L.; Bessho, K.; Takagi, J.; Sugai, M.; Tabata, Y.; Takahashi, K.
err分享
err收藏
Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 spike protein
errNATURE COMMUNICATIONS
IF15.7
err2023-02-04
err10
errOAAI
errKuhn, Christopher Cyrus; Basnet, Nirakar; Bodakuntla, Satish; Alvarez-Brecht, Pelayo; Nichols, Scott; Martinez-Sanchez, Antonio; Agostini, Lorenzo; Soh, Young-Min; Takagi, Junichi; Biertuempfel, Christian; Mizuno, Naoko
err分享
err收藏
Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2022-11-07
err10
errOAAI
errSakai, Katsuya; Sugano-Nakamura, Nozomi; Mihara, Emiko; Rojas-Chaverra, Nichole Marcela; Watanabe, Sayako; Sato, Hiroki; Imamura, Ryu; Voon, Dominic Chih-Cheng; Sakai, Itsuki; Yamasaki, Chihiro; Tateno, Chise; Shibata, Mikihiro; Suga, Hiroaki; Takagi, Junichi; Matsumoto, Kunio
err分享
err收藏
Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2022-10-24
err1
errOAAI
errSen, Soumyo; Spasic, Aleksandar; Sinha, Anjana; Wang, Jialing; Bush, Martin; Li, Jihong; Nesic, Dragana; Zhou, Yuchen; Angiulli, Gabriella; Morgan, Paul; Salas-Estrada, Leslie; Takagi, Junichi; Walz, Thomas; Coller, Barry S.; Filizola, Marta
err分享
err收藏
Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy
errCELL REPORTS METHODS
IF4.5
err2022-10-01
err6
errOAAI
errZhang, Qianli; Miyamoto, Akitoshi; Watanabe, Shin; Arimori, Takao; Sakai, Masanori; Tomisaki, Madoka; Kiuchi, Tai; Takagi, Junichi; Watanabe, Naoki
err分享
err收藏
Engineering ACE2 decoy receptors to combat viral escapability
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2022-10-01
err25
errOAAI
errArimori, Takao; Ikemura, Nariko; Okamoto, Toru; Takagi, Junichi; Standley, Daron M.; Hoshino, Atsushi
err分享
err收藏
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2022-06-22
err32
errOAAI
errIkemura, Nariko; Taminishi, Shunta; Inaba, Tohru; Arimori, Takao; Motooka, Daisuke; Katoh, Kazutaka; Kirita, Yuhei; Higuchi, Yusuke; Li, Songling; Suzuki, Tatsuya; Itoh, Yumi; Ozaki, Yuki; Nakamura, Shota; Matoba, Satoaki; Standley, Daron M.; Okamoto, Toru; Takagi, Junichi; Hoshino, Atsushi
err分享
err收藏
Functional role of the Frizzled linker domain in the Wnt signaling pathway
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-05-05
err11
errOAAI
errKo, Seung-Bum; Mihara, Emiko; Park, Yedarm; Roh, Kyeonghwan; Kang, Chanhee; Takagi, Junichi; Bang, Injin; Choi, Hee-Jung
err分享
err收藏
Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2022-02-16
err17
errOAAI
errHasegawa, Kana; Ikeda, Shunya; Yaga, Moto; Watanabe, Kouki; Urakawa, Rika; Iehara, Akie; Iwai, Mai; Hashiguchi, Seishin; Morimoto, Soyoko; Fujiki, Fumihiro; Nakajima, Hiroko; Nakata, Jun; Nishida, Sumiyuki; Tsuboi, Akihiro; Oka, Yoshihiro; Yoshihara, Satoshi; Manabe, Masahiro; Ichihara, Hiroyoshi; Mugitani, Atsuko; Aoyama, Yasutaka; Nakao, Takafumi; Hirose, Asao; Hino, Masayuki; Ueda, Shiho; Takenaka, Katsuto; Masuko, Takashi; Akashi, Koichi; Maruno, Takahiro; Uchiyama, Susumu; Takamatsu, Shinji; Wada, Naoki; Morii, Eiichi; Nagamori, Shushi; Motooka, Daisuke; Kanai, Yoshikatsu; Oji, Yusuke; Nakagawa, Tomoyoshi; Kijima, Noriyuki; Kishima, Haruhiko; Ikeda, Atsuyo; Ogino, Takayuki; Shintani, Yasushi; Kubo, Tateki; Mihara, Emiko; Yusa, Kosuke; Sugiyama, Haruo; Takagi, Junichi; Miyoshi, Eiji; Kumanogoh, Atsushi; Hosen, Naoki
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err收藏
Structural mechanism of laminin recognition by integrin
errNATURE COMMUNICATIONS
IF15.7
err2021-06-29
err50
errOAAI
errArimori, Takao; Miyazaki, Naoyuki; Mihara, Emiko; Takizawa, Mamoru; Taniguchi, Yukimasa; Cabanas, Carlos; Sekiguchi, Kiyotoshi; Takagi, Junichi
err分享
err收藏
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2
errNATURE COMMUNICATIONS
IF15.7
err2021-06-21
err90
errOAAI
errHiguchi, Yusuke; Suzuki, Tatsuya; Arimori, Takao; Ikemura, Nariko; Mihara, Emiko; Kirita, Yuhei; Ohgitani, Eriko; Mazda, Osam; Motooka, Daisuke; Nakamura, Shota; Sakai, Yusuke; Itoh, Yumi; Sugihara, Fuminori; Matsuura, Yoshiharu; Matoba, Satoaki; Okamoto, Toru; Takagi, Junichi; Hoshino, Atsushi
err分享
err收藏
Structural insights into integrin α5β1 opening by fibronectin ligand
errSCIENCE ADVANCES
IF12.5
err2021-05-07
err70
errOAAI
errSchumacher, Stephanie; Dedden, Dirk; Nunez, Roberto Vazquez; Matoba, Kyoko; Takagi, Junichi; Biertuempfel, Christian; Mizuno, Naoko
err分享
err收藏

研究方向

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合作学者
合作期刊
D
David M. Holtzman
H 指数: 204 · 论文数: 1.0K
T
Timothy A. Springer
H 指数: 165 · 论文数: 734
C
Christopher T. Walsh
H 指数: 144 · 论文数: 852
K
Kiyoshi Takeda
H 指数: 135 · 论文数: 669
Shigekazu Nagata 封面图
Shigekazu Nagata (Shigekazu Nagata)
H 指数: 133 · 论文数: 865
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