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M

Matthew J. Wakefield

walter and eliza hall institute of medical research
H指数:39
被引数:1.4万

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荣誉奖项

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Olaparib in HR-deficient, metastatic triple-negative breast and platinum-sensitive relapsed ovarian cancers without germline mutations in BRCA1/2: phase 2 EMBRACE trial

奥拉帕利在HR缺陷、转移性三阴性乳腺癌和铂敏感复发性卵巢癌中BRCA1/2无胚系突变患者中的疗效：EMBRACE二期临床试验

British Journal of Cancer
IF6.8
2026-07-080
OA
Katrin M. Sjoquist; Alexander Dobrovic; Kristy P. Robledo; Ksenija Nesic; Sally Baron-Hay; Sumitra Ananda; Nicole McCarthy; Jeffrey Goh; Christopher Steer; Nick Murray; Sonia Yip; Linda R. Mileshkin; J. Lynn Fink; Garry Chang; Lisa Bailey; Yvonne Lee; Danka S. Zebic; U. G. Imalki U. Kariyawasam; Kristy Shield-Artin; Andrew Jarratt; Justin Bedő; Anthony T. Papenfuss; Olga Kondrashova; Matthew J. Wakefield; Cassandra J. Vandenberg; Martin R. Stockler; Clare L. Scott; Paul M. Waring
High-throughput drug screening identifies EGFR/MAPK pathway targeting sensitivities in organoid models of ovarian carcinosarcoma
Journal of Experimental & Clinical Cancer Research
IF12.8
2026-01-060
OAAI
Andrew Farrell; Genevieve Dall; Cassandra J. Vandenberg; Kristy Shield-Artin; Elizabeth L. Kyran; Tim Blackmore; Ratana Lim; Rachael Taylor; Chloe Neagle; Gayanie Ratnayake; Tao Tan; Dmitri Mouradov; Anthony Hadla; Kate Jarman; Sally Beard; Andrew Jarratt; Jocelyn S. Penington; Matthew J. Wakefield; Anthony T. Papenfuss; Clare L. Scott; Holly E. Barker
Olaparib, durvalumab, and cyclophosphamide, and a prognostic blood signature in platinum-sensitive ovarian cancer: the randomized phase 2 SOLACE2 trial

奥拉帕利、度伐利尤单抗和环磷酰胺，以及铂敏感卵巢癌的预后血液特征：随机Ⅱ期SOLACE2试验

Nature Communications
IF15.7
2025-11-050
OA
Chee Khoon Lee; Apriliana E. R. Kartikasari; Nirashaa T. Bound; Katherine E. Francis; Kristy Shield-Artin; Justin Bedo; Ksenija Nesic; Katrina Diamante; Rachel L. O’Connell; Mutsa Madondo; Momodou Cox; Claire Davies; Cyril Deceneux; Georgia Goodchild; Andrew Jarratt; Emily Cassar; Hina Amer; U. G. Imalki U. Kariyawasam; Yeh Chen Lee; Janine Lombard; Sally Baron-Hay; Yoland Antill; Catherine Shannon; Sudarshan Selva-Nayagam; Philip Beale; Danka Zebic; Sandy Simon; Anneliese Linaker; Michael A. Quinn; Anthony T. Papenfuss; Matthew J. Wakefield; Cassandra J. Vandenberg; Michael Friedlander; Clare L. Scott; Magdalena Plebanski
Farletuzumab ecteribulin and MORAb-109, folate receptor alpha and mesothelin targeting antibody-drug conjugates, show activity in poor prognosis gynaecological cancer models

Farletuzumab ecteribulin和MORAb-109，靶向叶酸受体α和间皮素的抗体-药物偶联物，在预后不良的妇科癌症模型中显示出活性。

CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2025-03-120
OA
Nesic, Ksenija; Rybinski, Katherine; Ratnayake, Gayanie; Ho, Gwo-Yaw; Lim, Ratana; Radke, Marc; Neagle, Chloe; Swisher, Elizabeth M.; Wakefield, Matthew J.; Barker, Holly E.; Furuuchi, Keiji; Scott, Clare L.; Vandenberg, Cassandra J.
MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays

MaveDB 2024：一个经过整理的社区数据库，包含来自多重功能实验的超过七百万个变异效应。

GENOME BIOLOGY
IF9.4
2025-01-213
OA
Rubin, Alan F.; Stone, Jeremy; Bianchi, Aisha Haley; Capodanno, Benjamin J.; Da, Estelle Y.; Dias, Mafalda; Esposito, Daniel; Frazer, Jonathan; Fu, Yunfan; Grindstaff, Sally B.; Harrington, Matthew R.; Li, Iris; Mcewen, Abbye E.; Min, Joseph K.; Moore, Nick; Moscatelli, Olivia G.; Ong, Jesslyn; Polunina, Polina V.; Rollins, Joshua E.; Rollins, Nathan J.; Snyder, Ashley E.; Tam, Amy; Wakefield, Matthew J.; Starita, Lea M.; Bryant, Vanessa L.; Marks, Debora S.; Fowler, Douglas M.
SOLACE2: A phase II randomized trial of olaparib (O) and durvalumab (D) with or without low dose cyclophosphamide (LDCy) in platinum-sensitive recurrent ovarian cancer (PSROC)

SOLACE2：一项关于奥拉帕利（O）和度伐利尤单抗（D）联合或未联合低剂量环磷酰胺（LDCy）治疗铂敏感复发性卵巢癌（PSROC）的II期随机试验

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Scott, C. L.; Friedlander, M. L.; Francis, K.; Kartikasari, A. E. R.; Diamante, K.; Bound, N.; Davies, C.; O'Connell, R.; Lee, Y. C.; Lombard, J.; Baron-Hay, S. E.; Antill, Y.; Shannon, C.; Selva-Nayagam, S.; Beale, P. J.; Shield-Artin, K.; Wakefield, M.; Vandenberg, C.; Plebanski, M.; Lee, C. K.
BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance
MOLECULAR CANCER
IF33.9
2024-08-050
OAAI
Nesic, Ksenija; Krais, John J.; Wang, Yifan; Vandenberg, Cassandra J.; Patel, Pooja; Cai, Kathy Q.; Kwan, Tanya; Lieschke, Elizabeth; Ho, Gwo-Yaw; Barker, Holly E.; Bedo, Justin; Casadei, Silvia; Farrell, Andrew; Radke, Marc; Shield-Artin, Kristy; Penington, Jocelyn S.; Geissler, Franziska; Kyran, Elizabeth; Betsch, Robert; Xu, Lijun; Zhang, Fan; Dobrovic, Alexander; Olesen, Inger; Kristeleit, Rebecca; Oza, Amit; McNeish, Iain; Ratnayake, Gayanie; Traficante, Nadia; DeFazio, Anna; Bowtell, David D. L.; Harding, Thomas C.; Lin, Kevin; Swisher, Elizabeth M.; Kondrashova, Olga; Scott, Clare L.; Johnson, Neil; Wakefield, Matthew J.
The microtubule inhibitor eribulin demonstrates efficacy in platinum-resistant and refractory high-grade serous ovarian cancer patient-derived xenograft models

微管抑制剂eribulin在铂耐药和难治性高级浆液性卵巢癌患者来源的异种移植模型中显示出疗效

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
IF4.2
2023-11-221
OAAI
Ho, Gwo Yaw; Vandenberg, Cassandra J.; Lim, Ratana; Christie, Elizabeth L.; Garsed, Dale W.; Lieschke, Elizabeth; Nesic, Ksenija; Kondrashova, Olga; Ratnayake, Gayanie; Radke, Marc; Penington, Jocelyn S.; Carmagnac, Amandine; Heong, Valerie; Kyran, Elizabeth L.; Zhang, Fan; Traficante, Nadia; Huang, Ruby; Dobrovic, Alexander; Swisher, Elizabeth M.; McNally, Orla; Kee, Damien; Wakefield, Matthew J.; Papenfuss, Anthony T.; Bowtell, David D. L.; Barker, Holly E.; Scott, Clare L.
Interferon-ε is a tumour suppressor and restricts ovarian cancer
Nature
IF48.5
2023-08-160
PRE
Zoe R. C. Marks; Nicole K. Campbell; Niamh E. Mangan; Cassandra J. Vandenberg; Linden J. Gearing; Antony Y. Matthews; Jodee A. Gould; Michelle D. Tate; Georgie Wray-McCann; Le Ying; Sarah Rosli; Natasha Brockwell; Belinda S. Parker; San S. Lim; Maree Bilandzic; Elizabeth L. Christie; Andrew N. Stephens; Eveline de Geus; Matthew J. Wakefield; Gwo-Yaw Ho; Orla McNally; Iain A. McNeish; David D. L. Bowtell; Nicole A. de Weerd; Clare L. Scott; Nollaig M. Bourke; Paul J. Hertzog
Targeting homologous recombination deficiency in uterine leiomyosarcoma

靶向子宫平滑肌肉瘤的同源重组缺陷

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2023-05-0410
OAAI
Dall, Genevieve; Vandenberg, Cassandra J. J.; Nesic, Ksenija; Ratnayake, Gayanie; Zhu, Wenying; Vissers, Joseph H. A.; Bedo, Justin; Penington, Jocelyn; Wakefield, Matthew J. J.; Kee, Damien; Carmagnac, Amandine; Lim, Ratana; Shield-Artin, Kristy; Milesi, Briony; Lobley, Amanda; Kyran, Elizabeth L. L.; O'Grady, Emily; Tram, Joshua; Zhou, Warren; Nugawela, Devindee; Stewart, Kym Pham; Caldwell, Reece; Papadopoulos, Lia; Ng, Ashley P. P.; Dobrovic, Alexander; Fox, Stephen B. B.; McNally, Orla; Power, Jeremy D. D.; Meniawy, Tarek; Tan, Teng Han; Collins, Ian M. M.; Klein, Oliver; Barnett, Stephen; Olesen, Inger; Hamilton, Anne; Hofmann, Oliver; Grimmond, Sean; Papenfuss, Anthony T. T.; Scott, Clare L. L.; Barker, Holly E. E.
Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
CANCER RESEARCH
IF16.6
2022-10-0710
OAAI
Ho, Gwo Yaw; Kyran, Elizabeth L.; Bedo, Justin; Wakefield, Matthew J.; Ennis, Darren P.; Mirza, Hasan B.; Vandenberg, Cassandra J.; Lieschke, Elizabeth; Farrell, Andrew; Hadla, Anthony; Lim, Ratana; Dall, Genevieve; Vince, James E.; Chua, Ngee Kiat; Kondrashova, Olga; Upstill-Goddard, Rosanna; Bailey, Ulla-Maja; Dowson, Suzanne; Roxburgh, Patricia; Glasspool, Rosalind M.; Bryson, Gareth; Biankin, Andrew V.; Cooke, Susanna L.; Ratnayake, Gayanie; McNally, Orla; Traficante, Nadia; DeFazio, Anna; Weroha, S. John; Bowtell, David D.; McNeish, Iain A.; Papenfuss, Anthony T.; Scott, Clare L.; Barker, Holly E.
Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes
CLINICAL CANCER RESEARCH
IF10.2
2022-10-0711
OAAI
Meagher, Nicola S.; Gorringe, Kylie L.; Wakefield, Matthew; Bolithon, Adelyn; Pang, Chi Nam Ignatius; Chiu, Derek S.; Anglesio, Michael S.; Mallitt, Kylie-Ann; Doherty, Jennifer A.; Harris, Holly R.; Schildkraut, Joellen M.; Berchuck, Andrew; Cushing-Haugen, Kara L.; Chezar, Ksenia; Chou, Angela; Tan, Adeline; Alsop, Jennifer; Barlow, Ellen; Beckmann, Matthias W.; Boros, Jessica; Bowtell, David D. L.; Brand, Alison H.; Brenton, James D.; Campbell, Ian; Cheasley, Dane; Cohen, Joshua; Cybulski, Cezary; Elishaev, Esther; Erber, Ramona; Farrell, Rhonda; Fischer, Anna; Fu, Zhuxuan; Gilks, Blake; Gill, Anthony J.; Gourley, Charlie; Grube, Marcel; Harnett, Paul R.; Hartmann, Arndt; Hettiaratchi, Anusha; Hogdall, Claus K.; Huzarski, Tomasz; Jakubowska, Anna; Jimenez-Linan, Mercedes; Kennedy, Catherine J.; Kim, Byoung-Gie; Kim, Jae-Weon; Kim, Jae-Hoon; Klett, Kayla; Koziak, Jennifer M.; Lai, Tiffany; Laslavic, Angela; Lester, Jenny; Leung, Yee; Li, Na; Liauw, Winston; Lim, Belle W. X.; Linder, Anna; Lubinski, Jan; Mahale, Sakshi; Mateoiu, Constantina; McInerny, Simone; Menkiszak, Janusz; Minoo, Parham; Mittelstadt, Suzana; Morris, David; Orsulic, Sandra; Park, Sang-Yoon; Pearce, Celeste Leigh; Pearson, John, V; Pike, Malcolm C.; Quinn, Carmel M.; Mohan, Ganendra Raj; Rao, Jianyu; Riggan, Marjorie J.; Ruebner, Matthias; Salfinger, Stuart; Scott, Clare L.; Shah, Mitul; Steed, Helen; Stewart, Colin J. R.; Subramanian, Deepak; Sung, Soseul; Tang, Katrina; Timpson, Paul; Ward, Robyn L.; Wiedenhoefer, Rebekka; Thorne, Heather; Cohen, Paul A.; Crowe, Philip; Fasching, Peter A.; Gronwald, Jacek; Hawkins, Nicholas J.; Hogdall, Estrid; Huntsman, David G.; James, Paul A.; Karlan, Beth Y.; Kelemen, Linda E.; Kommoss, Stefan; Konecny, Gottfried E.; Modugno, Francesmary; Park, Sue K.; Staebler, Annette; Sundfeldt, Karin; Wu, Anna H.; Talhouk, Aline; Pharoah, Paul D. P.; Anderson, Lyndal; DeFazio, Anna; Kobel, Martin; Friedlander, Michael L.; Ramus, Susan J.
Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma
CANCER RESEARCH
IF16.6
2021-07-2860
OA
Nesic, Ksenija; Kondrashova, Olga; Hurley, Rachel M.; McGehee, Cordelia D.; Vandenberg, Cassandra J.; Ho, Gwo-Yaw; Lieschke, Elizabeth; Dall, Genevieve; Bound, Nirashaa; Shield-Artin, Kristy; Radke, Marc; Musafer, Ashan; Chai, Zi Qing; Ghamsari, Mohammad Reza Eftekhariyan; Harrell, Maria, I; Kee, Damien; Olesen, Inger; McNally, Orla; Traficante, Nadia; DeFazio, Anna; Bowtell, David D. L.; Swisher, Elizabeth M.; Weroha, S. John; Nones, Katia; Waddell, Nicola; Kaufmann, Scott H.; Dobrovic, Alexander; Wakefield, Matthew J.; Scott, Clare L.
Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance
NAR CANCER
IF3.2
2021-07-0923
OAAI
Hurley, Rachel M.; McGehee, Cordelia D.; Nesic, Ksenija; Correia, Cristina; Weiskittel, Taylor M.; Kelly, Rebecca L.; Venkatachalam, Annapoorna; Hou, Xiaonan; Pathoulas, Nicholas M.; Meng, X. Wei; Kondrashova, Olga; Radke, Marc R.; Schneider, Paula A.; Flatten, Karen S.; Peterson, Kevin L.; Becker, Marc A.; Wong, Ee Ming; Southey, Melissa S.; Dobrovic, Alexander; Lin, Kevin K.; Harding, Thomas C.; McNeish, Iain; Ross, Christian A.; Wagner, Jill M.; Wakefield, Matthew J.; Scott, Clare L.; Haluska, Paul; Hendrickson, Andrea E. Wahner; Karnitz, Larry M.; Swisher, Elizabeth M.; Li, Hu; Weroha, S. John; Kaufmann, Scott H.
Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors
CELL DEATH & DISEASE
IF9.6
2021-03-122
OAAI
Grohmann, Christoph; Walker, Francesca; Devlin, Mark; Luo, Meng-Xiao; Chueh, Anderly C.; Doherty, Judy; Vaillant, Francois; Ho, Gwo-Yaw; Wakefield, Matthew J.; Weeden, Clare E.; Kamili, Alvin; Murray, Jayne; Po'uha, Sela T.; Weinstock, Janet; Kane, Serena R.; Faux, Maree C.; Broekhuizen, Esmee; Zheng, Ye; Shield-Artin, Kristy; Kershaw, Nadia J.; Tan, Chin Wee; Witchard, Helen M.; Ebert, Gregor; Charman, Susan A.; Street, Ian; Kavallaris, Maria; Haber, Michelle; Fletcher, Jamie I.; Asselin-Labat, Marie-Liesse; Scott, Clare L.; Visvader, Jane E.; Lindeman, Geoffrey J.; Watson, Keith G.; Burgess, Antony W.; Lessene, Guillaume
Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses
MODERN PATHOLOGY
IF5.5
2021-01-0128
OAAI
Kang, Eun Young; Cheasley, Dane; LePage, Cecile; Wakefield, Matthew J.; Torres, Michelle da Cunha; Rowley, Simone; Salazar, Carolina; Xing, Zhongyue; Allan, Prue; Bowtell, David D. L.; Mes-Masson, Anne-Marie; Provencher, Diane M.; Rahimi, Kurosh; Kelemen, Linda E.; Fasching, Peter A.; Doherty, Jennifer A.; Goodman, Marc T.; Goode, Ellen L.; Deen, Suha; Pharoah, Paul D. P.; Brenton, James D.; Sieh, Weiva; Mateoiu, Constantina; Sundfeldt, Karin; Cook, Linda S.; Le, Nhu D.; Anglesio, Michael S.; Gilks, C. Blake; Huntsman, David G.; Kennedy, Catherine J.; Traficante, Nadia; DeFazio, Anna; Kaufmann, Scott; Churchman, Michael; Gourley, Charlie; Stephens, Andrew N.; Meagher, Nicola S.; Ramus, Susan J.; Antill, Yoland C.; Campbell, Ian; Scott, Clare L.; Kobel, Martin; Gorringe, Kylie L.

研究方向

暂未获取到该数据
C
Clare L. Scott
H 指数:81论文数:504被引数:3.8万
O
Olga Kondrashova
H 指数:22论文数:155被引数:2,764
G
Gwo‐Yaw Ho
H 指数:15论文数:80被引数:1,763
K
Ksenija Nesic
H 指数:7论文数:26被引数:604
C
Cassandra J. Vandenberg
H 指数:24论文数:101被引数:3,903
D
David D.L. Bowtell
H 指数:116论文数:1,068被引数:7.3万
E
Elizabeth M. Swisher
H 指数:103论文数:743被引数:6.6万
K
Kristy Shield‐Artin
H 指数:10论文数:38被引数:1,390
A
Anthony T. Papenfuss
H 指数:69论文数:475被引数:1.7万
H
Holly E. Barker
H 指数:21论文数:173被引数:5,576