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Investigational Use of Real-World Data as a Hybrid Control in Pancreatic Ductal Adenocarcinoma from the Randomized Phase Ib/II MORPHEUS Trial Ko, Andrew H.; Oh, Do-Youn; Lau, Janet; Mhatre, Shivani K.; Ci, Bo; Machado, Robson; Li, Shi; Bretscher, Michael T.; Reyes-Rivera, Irmarie; Zhu, Jiawen; Zhang, Xiaosong; Patel, Jilpa; Psioda, Matthew A.; Ponz-Sarvise, Mariano 分享 收藏
Neoadjuvant therapy versus upfront surgery in resectable pancreatic cancer: reconstructed patient-level meta-analysis of randomized clinical trials Aliseda, Daniel; Marti-Cruchaga, Pablo; Zozaya, Gabriel; Blanco, Nuria; Ponz, Mariano; Chopitea, Ana; Rodriguez, Javier; Castanon, Eduardo; Pardo, Fernando; Rotellar, Fernando 分享 收藏
Exploratory biomarker evaluation of the randomized Phase 2 cohort of CM24 in combination with nivolumab and chemotherapy in advanced/metastatic pancreatic cancer Macarulla, Teresa; Cecchini, Michael; Garcia-Carbonero, Rocio; Golan, Talia; Perets, Ruth; Borazanci, Erkut; Pedegral, Manuel; Ponz-Sarvise, Mariano; Al Hallak, Mohammed Najeeb; Pant, Shubham; Boni, Valentina; Saavedra, Omar; Jose de Miguel-Luken, Maria; Leal, Alexis D.; Munoz Martin, Andres J.; Sauri-Nadal, Tamara; Schickler, Michael; Ben David, Hava; Reuveni, Hadas 分享 收藏
Chemo-immunotherapy combination of mFOLFOX6, bevacizumab and atezolizumab after first-line therapy for advanced biliary tract cancer: The COMBATBIL imCORE trial mFOLFOX6、贝伐珠单抗和阿替利珠单抗的化疗-免疫联合疗法在一线疗法后的晚期胆道癌中的应用：COMBATBIL imCORE试验 Ponz-Sarvise, M.; Gromke, T.; Magdalena, A. Landa; Richly, H.; Liffers, S-T; Kasper-Virchow, S.; Garonce-Hediger, R.; Alvarez, E. Castanon; Paredes, L. Ceniceros; Ortega, A. Chopitea; Siveke, J. T. 分享 收藏
First results for intravenous (IV) VSV-GP (BI 1831169) in patients (pts) with advanced solid tumors from the 1456-0001 study 1456-0001研究中的首批结果：静脉注射（IV）VSV-GP（BI 1831169）在晚期实体瘤患者（pts）中的应用 Oliva Bernal, M.; Greillier, L.; Ponz-Sarvise, M.; Moreno Garcia, V.; Prenen, H.; Wolf, D.; Quinson, A-M.; Luecke, S.; Hern, V.; Porosnicu, M. 分享 收藏
Leveraging innate and adaptive immunity with AFM24 and atezolizumab in metastatic gastric cancer 利用AFM24和atezolizumab增强固有免疫和适应性免疫在转移性胃癌中的应用 Santa Gadea, O. Saavedra; Oberoi, A.; Lopez, J. S.; Cervantes, A.; Ponz-Sarvise, M.; Kim, H. R.; El-Khoueiry, A. B.; Shim, B.; Kim, J. W.; Boni, V.; Lugowska, I.; Szczylik, C.; Rogowski, W.; Mandziuk, S.; Ramlau, R.; Gaertner, U.; Lutkewitz, S.; Schuetz, D.; Emig, M.; Morales-Espinosa, D. 分享 收藏
A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma Coveler, Andrew L.; Reilley, Matthew J.; Zalupski, Mark; Macarulla, Teresa; Fountzilas, Christos; Ponz-Sarvise, Mariano; Nagrial, Adnan; Uboha, Nataliya V.; Frentzas, Sophia; Overman, Michael; Noonan, Anne; Messersmith, Wells A.; Pavlakis, Nick; Mettu, Niharika B.; Bisha, Ina; Wang, Ying; Smith, Paul; Murtomaki, Elina; Bielska, Agata A.; Bragulat, Veronique; Cooper, Zachary A.; Kumar, Rakesh; Spigel, David R. 分享 收藏
Phase II Study to Determine the Antitumor Activity and Safety of Simlukafusp Alfa (FAP-IL2v) Combined with Atezolizumab in Esophageal Cancer Prenen, Hans; Deva, Sanjeev; Keam, Bhumsuk; Lindsay, Colin R.; Lugowska, Iwona; Yang, James C.; Longo, Federico; de Miguel, Maria; Ponz-Sarvise, Mariano; Ahn, Myung-Ju; Gumus, Mahmut; Champiat, Stephane; Italiano, Antoine; Salas, Sebastien; Perets, Ruth; Arslan, Cagatay; Cho, Byoung C.; Evers, Stefan; Boetsch, Christophe; Marbach, Daniel; Dejardin, David; Sleiman, Nassim; Ardeshir, Caroline; Richard, Muriel; Charo, Jehad; Kraxner, Anton; Keshelava, Nino; Teichgraeber, Volker; Moreno, Victor 分享 收藏
Preliminary safety and anti-tumor activity of RMC-6291, a first-in-class, tri-complex KRASG12C(ON) inhibitor, in patients with or without prior KRASG12C(OFF) inhibitor treatment Janne, Pasi A.; Bigot, Frederic; Papadopoulos, Kyriakos; Eberst, Lauriane; Sommerhalder, David; Lebellec, Loic; Voon, Pei Jye; Pellini, Bruna; Kalinka, Ewa; Arbour, Kathryn; Herzberg, Benjamin; Boni, Valentina; Bordenave, Stephanie; Lee, Hyun Woo; Ou, Sai I.; Riess, Jonathan Wesley; Beck, Joseph T.; Ponz-Sarvise, Mariano; Ascierto, Paolo Antonio; Choi, Yoon Ji; Yang, Michelle; Bao, Lei; Raman, Rakesh; Yang, Luxi; Mu, Yunming; Wong, Sofia; Dua, Richa; Johnson, Melissa 分享 收藏
Clinical activity of lirafugratinib (RLY-4008), a highly selective FGFR2 inhibitor, in patients with advanced FGFR2-altered solid tumors: The ReFocus study Schram, Alison M.; Subbiah, Vivek; Liao, Chih-Yi (Andy); Moreno, Victor; Desamparados, Roda; Ponz-Sarvise, Mariano; Dotan, Efrat; Cassier, Philippe Alexandre; Moreno, Irene; Varkaris, Andreas; Kim, Richard D.; Garralda, Elena; Opdam, Frans; Tai, David; Italiano, Antoine; Oh, Do-Youn; Goyal, Lipika; Fontana, Elise; Liu, Jia; Boukovala, Myrto; Ghiringelli, Francois; Borad, Mitesh J.; Babiker, Hani; Jin, Zhaohui; Millward, Michael; Yachnin, Jeffrey; Kamath, Suneel Deepak; Coward, Jermaine M.; Yoo, Changhoon; Kelley, Robin Kate; Sahai, Vaibhav; Bridgewater, John; Springfield, Christoph; Florou, Vaia; El-Khoueiry, Anthony; Eskens, Ferry; Lin, Bruce; Paulson, Scott; Curigliano, Giuseppe; Murphy, Meredith; Deary, Alicia; Ricard, Fabien; Jen, Kai Yu; Ramirez, Florence (Tianhui); Blakesley, Rick E.; Schmidt-Kittler, Oleg; Mar, Brenton G.; Park, Joon Oh; Hollebecque, Antoine 分享 收藏
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; Lopez, Ines; Rodriguez-Remirez, Maria; Palomino-Echeverria, Sara; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz-Sarvise, Mariano; Pineda-Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silve 分享 收藏
Identification of 'secondary' germline cancer predisposition variants from somatic tumour testing: Should we evolve towards universal screening? Gallego Martinez, A.; Imizcoz, T.; Sanchez-Lorenzo, L.; Mora, M.; Dominguez, D.; Gurpide, A.; Espinos Jimenez, J.; Aramendia, J. M.; Chopitea Ortega, A.; Santisteban Eslava, M.; Ponz-Sarvise, M.; Gonzalez, L.; Landa Magdalena, A.; Sanmamed, M. F.; Alkorta-Aranburu, G.; Rodriguez Rodriguez, J.; Herraiz Bayod, T.; Gonzalez Martin, A.; Patino-Garcia, A. 分享 收藏
Circulating tumor DNA (ctDNA) profile in patients (pts) with pancreatic cancer (PC): A multicenter experience and challenges for clinical application Ghiglione, L.; Munoz i Carrillo, F. J.; Esposito, F. M.; Pesantez Coronel, D.; Delcuratolo, M. D.; Garcia-Carbonero, R.; Fabregat-Franco, C.; Alonso, G.; Macarulla, T.; Ceniceros Paredes, L.; Ponz-Sarvise, M.; Visa Turmo, L.; Lopez Munoz, A. M.; Pastor, B.; Indacochea, A.; Vicente Lazcano, M. P.; Riva, F. N.; Prat, A.; Victoria, I.; Sauri Nadal, T. 分享 收藏
MONEO: Phase II study of avelumab (Av) plus FLOT in the peri-operative treatment for patients (pts) with resectable gastric or gastroesophageal junction cancer (GC) Alsina, M.; Ponz-Sarvise, M.; Garcia, D. Lopez; Villacampa, G.; De Andrea, C.; Ochoa, C.; Lopez-Janeiro, A.; Jimenez-Fonseca, P.; Arrazubi, V.; Garcia, M. Diez; Sanz-Garcia, E.; de Castro, E. Martinez; Sanchez, R. Guardeno; Campos, M. Calvo; Sanchez, C. Buges; Longo, F.; Navarro, V.; Gros, A.; Vivancos, A.; Tabernero, J.; Munoz, S.; Melero, I. 分享 收藏
A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors Melero, Ignacio; Tanos, Tamara; Bustamante, Mariana; Sanmamed, Miguel F.; Calvo, Emiliano; Moreno, Irene; Moreno, Victor; Hernandez, Tatiana; Garcia, Maria Martinez; Rodriguez-Vida, Alejo; Tabernero, Josep; Azaro, Analia; Ponz-Sarvise, Mariano; Spanggaard, Iben; Rohrberg, Kristoffer; Guarin, Ernesto; Nuesch, Eveline; Davydov, Iakov I.; Ooi, Chiahuey; Duarte, Jose; Chesne, Evelyne; McIntyre, Christine; Ceppi, Maurizio; Canamero, Marta; Krieter, Oliver 分享 收藏
RO7119929, a TLR7 agonist prodrug, induces local inflammation of the tumor microenvironment (TME) by reprogramming myeloid cells in patients (pts) with advanced primary or metastatic liver cancers Fabregat-Franco, Carles; Yoo, Changhoon; Sangro, Bruno; Qvortrup, Camilla; Kim, Hyung-Don; Macarulla, Teresa; Ponz-Sarvise, Mariano; Lin, Chia-Chi; Oh, Do-Youn; Yau, Thomas; Bessa, Juliana; Schwalie, Petra C.; Dettling, Steffen; Schlenker, Ramona; Riede, Natascha; Hall, Elia; Lichtenegger, Felix; Kratochwil, Nicole; Poschinger, Thomas; Jiang, Zhiwen; Jiang, Tianyi; Sie, Christina Godfried; Te-Ying, Audrey Yeo; Schiff, Christina; Hoves, Sabine; Cannarile, Michael 分享 收藏
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