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Fotios Sampaziotis

wellcome mrc cambridge stem cell institute
H指数:22
被引数:6,616

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Pharmacological inhibition of METTL1 as a therapy against solid and blood cancers

METTL1的药理学抑制作为对抗实体瘤和血液癌的疗法

Nature
IF48.5
2026-10-280
OAAI
Eliza Yankova; Alexandra Sapetschnig; Beth Thomas; Siân Evans; Maria Eleftheriou; Malgorzata Gozdecka; Harry Fischl; Teresa Brevini; Rachael Wilson; Sarah J. Bucknell; Andrew Hutchin; Carmen M. Livi; George Giotopoulos; Ryan Asby; Laura Bond; Aleksandra Azevedo; Natalie Webster; Jack Rogan; James Russell; Byron Andrews; Hendrik Weisser; Joanna Baxter; Judith López-Luis; Giovanna Mantica; Jake Tobin; Diego Lopez-Leon; Dean C. Pask; Vidur Tandon; Richard Fosbeary; Sapphire Sawyer; Sunay Usluer; Nithila Joseph; Evangelia Stamou; Maria T. Bejar; Yogeshkumar Malam; Roland Rad; Elisa Laurenti; Juan Li; Maria P. Alcolea; David J. Adams; Walid T. Khaled; Fotios Sampaziotis; George S. Vassiliou; Brian J. P. Huntly; Oliver Rausch; Konstantinos Tzelepis
The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation

NAT10的RNA解旋酶结构域通过促进低修饰核糖体的生物发生来增强癌细胞增殖

Nature Communications
IF15.7
2026-08-080
OA
Mahmood H. Dalhat; Sharath Narayan; Maria Eleftheriou; James Russell; James Heslop; Hannah Serio; Khulood A. Alzahrani; Adam Suh; Ajay Edakkara; Sweta Raikundalia; Lea Landmann; Ryan Asby; Evangelia Stamou; Judith López; Yogeshkumar Malam; Demetrios Aspris; Emmely A. Patrasso; Stephanie Mou; George Giotopoulos; Walid T. Khaled; Brian J. P. Huntly; Fotios Sampaziotis; Konstantinos Tzelepis; Daniel Arango
Successful AAV8 gene therapy on hepatic ex situ machine perfusion for mitochondrial neurogastrointestinal encephalomyopathy

成功的AAV8基因治疗肝异位机器灌注治疗线粒体神经胃肠脑肌病

Journal of Hepatology
IF33
2025-08-060
PREAI
Teresa Brevini; Lisa Swift; Helen Reynolds; John Ong; Richard J. Stopforth; Yogeshkumar Malam; Harry V.M. Spiers; Emilija Jovanovic; Miki Scaravaglio; Vitushan Vakeeswarasarma; James Heslop; Erin Emmett; Brock Andreatta; Emmanouil Athanasiadis; Tessa M. Cacciottolo; Claudia D. Fuchs; Michael Trauner; Sarah A. Hosgood; Teik Choon See; Pavlos Pantelis; Dora Foukaneli; William T.H. Gelson; Paul Gibbs; Kieren Allinson; Gavin J. Pettigrew; Adam Duckworth; Anna L. Paterson; Vassilis G. Gorgoulis; Richard J. Thompson; Arthur Kaser; Vasilis Kosmoliaptsis; Patrick F. Chinnery; Ramon Marti; Jelle van den Ameele; Gwilym J. Webb; Christopher J.E. Watson; Andrew J. Butler; Fotios Sampaziotis
Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog (vol 5, pg 162, 2025)

使用一种包封于胶束中的苏丹黑B偶联类似物构建选择性细胞凋亡平台（卷5，页162，2025）

NATURE AGING
IF19.4
2025-01-311
OA
Magkouta, Sophia; Veroutis, Dimitris; Papaspyropoulos, Angelos; Georgiou, Maria; Lougiakis, Nikolaos; Pippa, Natassa; Havaki, Sophia; Palaiologou, Anastasia; Thanos, Dimitris-Foivos; Kambas, Konstantinos; Lagopati, Nefeli; Boukos, Nikos; Pouli, Nicole; Marakos, Panagiotis; Kotsinas, Athanassios; Thanos, Dimitris; Evangelou, Konstantinos; Sampaziotis, Fotios; Tamvakopoulos, Constantin; Pispas, Stergios; Petty, Russell; Kotopoulos, Nicholas; Gorgoulis, Vassilis G.
Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog

利用微球包封的苏丹黑B偶联类似物构建选择性 senolytic 平台

NATURE AGING
IF19.4
2024-12-274
OA
Magkouta, Sophia; Veroutis, Dimitris; Papaspyropoulos, Angelos; Georgiou, Maria; Lougiakis, Nikolaos; Pippa, Natassa; Havaki, Sophia; Palaiologou, Anastasia; Thanos, Dimitris-Foivos; Kambas, Konstantinos; Lagopati, Nefeli; Boukos, Nikos; Pouli, Nicole; Marakos, Panagiotis; Kotsinas, Athanassios; Thanos, Dimitris; Evangelou, Konstantinos; Sampaziotis, Fotios; Tamvakopoulos, Constantin; Pispas, Stergios; Petty, Russell; Kotopoulos, Nicholas; Gorgoulis, Vassilis G.
Gut Pathobiont-Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis-Associated Inflammatory Bowel Disease
GASTROENTEROLOGY
IF25.1
2024-11-012
PRE
Dorner, Heidrun; Stolzer, Iris; Mattner, Jochen; Kaminski, Sophie; Leistl, Sofia; Edrich, Lisa-Maria; Schwendner, Raphael; Hobauer, Julia; Sebald, Adrian; Leikam, Stefanie; Acera, Miguel Gonzalez; Duell, Miriam; Lang, Roland; Seidel, Gerald; Seitz, Tatjana; Hellerbrand, Claus; Fuhrmann, Gregor; Distler, Ute; Tenzer, Stefan; Eichhorn, Phillip; Vieth, Michael; Schramm, Christoph; Arnold, Philipp; Becker, Christoph; Weidinger, Carl; Siegmund, Britta; Atreya, Raja; Leppkes, Moritz; Naschberger, Elisabeth; Sampaziotis, Fotios; Dietrich, Peter; Rauh, Manfred; Wirtz, Stefan; Kremer, Andreas E.; Neurath, Markus F.; Guenther, Claudia
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

FXR抑制可通过减少ACE2来预防SARS-CoV-2感染

Nature
IF48.5
2022-12-050
OAAI
Teresa Brevini; Mailis Maes; Gwilym J. Webb; Binu V. John; Claudia D. Fuchs; Gustav Buescher; Lu Wang; Chelsea Griffiths; Marnie L. Brown; William E. Scott; Pehuén Pereyra-Gerber; William T. H. Gelson; Stephanie Brown; Scott Dillon; Daniele Muraro; Jo Sharp; Megan Neary; Helen Box; Lee Tatham; James Stewart; Paul Curley; Henry Pertinez; Sally Forrest; Petra Mlcochova; Sagar S. Varankar; Mahnaz Darvish-Damavandi; Victoria L. Mulcahy; Rhoda E. Kuc; Thomas L. Williams; James A. Heslop; Davide Rossetti; Olivia C. Tysoe; Vasileios Galanakis; Marta Vila-Gonzalez; Thomas W. M. Crozier; Johannes Bargehr; Sanjay Sinha; Sara S. Upponi; Corrina Fear; Lisa Swift; Kourosh Saeb-Parsy; Susan E. Davies; Axel Wester; Hannes Hagström; Espen Melum; Darran Clements; Peter Humphreys; Jo Herriott; Edyta Kijak; Helen Cox; Chloe Bramwell; Anthony Valentijn; Christopher J. R. Illingworth; Bassam Dahman; Dustin R. Bastaich; Raphaella D. Ferreira; Thomas Marjot; Eleanor Barnes; Andrew M. Moon; Alfred S. Barritt; Ravindra K. Gupta; Stephen Baker; Anthony P. Davenport; Gareth Corbett; Vassilis G. Gorgoulis; Simon J. A. Buczacki; Joo-Hyeon Lee; Nicholas J. Matheson; Michael Trauner; Andrew J. Fisher; Paul Gibbs; Andrew J. Butler; Christopher J. E. Watson; George F. Mells; Gordon Dougan; Andrew Owen; Ansgar W. Lohse; Ludovic Vallier; Fotios Sampaziotis
Single-cell atlas of human liver development reveals pathways directing hepatic cell fates

人类肝脏发育的单细胞图谱揭示了指导肝细胞命运的途径

NATURE CELL BIOLOGY
IF19.1
2022-09-1542
OAAI
Wesley, Brandon T.; Ross, Alexander D. B.; Muraro, Daniele; Miao, Zhichao; Saxton, Sarah; Tomaz, Rute A.; Morell, Carola M.; Ridley, Katherine; Zacharis, Ekaterini D.; Petrus-Reurer, Sandra; Kraiczy, Judith; Mahbubani, Krishnaa T.; Brown, Stephanie; Garcia-Bernardo, Jose; Alsinet, Clara; Gaffney, Daniel; Horsfall, Dave; Tysoe, Olivia C.; Botting, Rachel A.; Stephenson, Emily; Popescu, Dorin-Mirel; MacParland, Sonya; Bader, Gary; McGilvray, Ian D.; Ortmann, Daniel; Sampaziotis, Fotios; Saeb-Parsy, Kourosh; Haniffa, Muzlifah; Stevens, Kelly R.; Zilbauer, Matthias; Teichmann, Sarah A.; Vallier, Ludovic
Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids

人胆道组织和相应的体外衍生类器官的区域差异

HEPATOLOGY
IF15.8
2021-02-0667
OAAI
Rimland, Casey A.; Tilson, Samantha G.; Morell, Carola M.; Tomaz, Rute A.; Lu, Wei-Yu; Adams, Simone E.; Georgakopoulos, Nikitas; Otaizo-Carrasquero, Francisco; Myers, Timothy G.; Ferdinand, John R.; Gieseck, Richard L., III; Sampaziotis, Fotios; Tysoe, Olivia C.; Ross, Alexander; Kraiczy, Judith M.; Wesley, Brandon; Muraro, Daniele; Zilbauer, Matthias; Oniscu, Gabriel C.; Hannan, Nicholas R. F.; Forbes, Stuart J.; Saeb-Parsy, Kourosh; Wynn, Thomas A.; Vallier, Ludovic
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
Science
IF45.8
2021-01-010
OA
Fotios Sampaziotis; Daniele Muraro; Olivia Tysoe; Stephen J. Sawiak; Timothy E. Beach; Edmund M. Godfrey; Sara S. Upponi; Teresa Brevini; Brandon Tyler Wesley; José Garcia‐Bernardo; Krishnaa T. A. Mahbubani; Giovanni Canu; Richard L. Gieseck; Natalie Lie Berntsen; Victoria Mulcahy; Keziah Crick; Corrina Fear; Sharayne Robinson; Lisa Swift; Laure Gambardella; Johannes Bargehr; Daniel Ortmann; Stephanie Emma Brown; Anna Osnato; Michael P. Murphy; Gareth Corbett; William Gelson; George F. Mells; Peter D. Humphreys; Susan E. Davies; Irum Amin; Paul Gibbs; Sanjay Sinha; Sarah Amalia Teichmann; Andrew J. Butler; Teik Choon See; Espen Melum; Christopher J.E. Watson; Kourosh Saeb‐Parsy; Ludovic Vallier
Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration
NATURE BIOTECHNOLOGY
IF41.7
2019-08-02148
OAAI
Bargehr, Johannes; Ong, Lay Ping; Colzani, Maria; Davaapil, Hongorzul; Hofsteen, Peter; Bhandari, Shiv; Gambardella, Laure; Le Novere, Nicolas; Iyer, Dharini; Sampaziotis, Fotios; Weinberger, Florian; Bertero, Alessandro; Leonard, Andrea; Bernard, William G.; Martinson, Amy; Figg, Nichola; Regnier, Michael; Bennett, Martin R.; Murry, Charles E.; Sinha, Sanjay

研究方向

暂未获取到该数据
L
Ludovic Vallier
H 指数:69论文数:302被引数:2.2万
T
Teresa Brevini
H 指数:11论文数:34被引数:2,164
K
Kourosh Saeb‐Parsy
H 指数:67论文数:308被引数:2.7万
O
Olivia Tysoe
H 指数:9论文数:101被引数:1,479
E
Espen Melum
H 指数:41论文数:184被引数:7,116
J
Johannes Bargehr
H 指数:14论文数:44被引数:1,497
N
Nicholas R. F. Hannan
H 指数:23论文数:42被引数:5,243
A
Alessandro Bertero
H 指数:26论文数:79被引数:3,889
M
Miguel Cardoso de Brito
H 指数:7论文数:20被引数:1,279
S
Sanjay Sinha
H 指数:40论文数:216被引数:8,368