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IL-33/ST2 signaling in ILC2s drives exhaustion and myeloid skewing of HSCs in response to hematopoietic stress and aging IL-33/ST2信号在ILC2s中驱动造血应激和衰老条件下HSCs的耗竭和髓系偏移。 Naef, Pascal; Jaeger-Ruckstuhl, Carla A.; Schnuriger, Noah; Forster, Stefan; Monteiro, Ine s; Brigger, Daniel; Eggel, Alexander; Kessenbrock, Kai; Riether, Carsten; Ochsenbein, Adrian F. 分享 收藏
IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy Rubino, Viviana; Huppi, Michelle; Hopner, Sabine; Tortola, Luigi; Schnuriger, Noah; Legenne, Hugo; Taylor, Lea; Voggensperger, Svenja; Keller, Irene; Bruggman, Remy; Kronig, Marie-Noelle; Bacher, Ulrike; Kopf, Manfred; Ochsenbein, Adrian F.; Riether, Carsten 分享 收藏
A phase Ib/II randomized, open-label drug repurposing trial of glutamate signaling inhibitors in combination with chemoradiotherapy in patients with newly diagnosed glioblastoma: the GLUGLIO trial protocol 新诊断的胶质母细胞瘤患者中谷氨酸信号抑制剂联合放化疗的Ib/II期随机，开放标签药物再利用试验: GLUGLIO试验方案 Mastall, Maximilian; Roth, Patrick; Bink, Andrea; Fischer Maranta, Angela; Laubli, Heinz; Hottinger, Andreas Felix; Hundsberger, Thomas; Migliorini, Denis; Ochsenbein, Adrian; Seystahl, Katharina; Imbach, Lukas; Hortobagyi, Tibor; Held, Leonhard; Weller, Michael; Wirsching, Hans-Georg 分享 收藏
Tumour mutations in long noncoding RNAs enhance cell fitness (vol 14, 3342, 2023) Esposito, Roberta; Lanzos, Andres; Uroda, Tina; Ramnarayanan, Sunandini; Buechi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; Mccluggage, Finn; Medo, Matus; Basile, Giulia; Meise, Dominik F.; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; Bosch-Guiteras, Nuria; Andrades, Alvaro; Tham, Ai Ming; Roemmele, Michaela; Medina, Pedro P.; Ochsenbein, Adrian F.; Riether, Carsten; Kruithof-de Julio, Marianna; Zimmer, Yitzhak; Medova, Michaela; Stroka, Deborah; Fox, Archa; Johnson, Rory 分享 收藏
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Tumour mutations in long noncoding RNAs enhance cell fitness Esposito, Roberta; Lanzos, Andres; Uroda, Tina; Ramnarayanan, Sunandini; Buechi, Isabel; Polidori, Taisia; Guillen-Ramirez, Hugo; Mihaljevic, Ante; Merlin, Bernard Mefi; Mela, Lia; Zoni, Eugenio; Hovhannisyan, Lusine; McCluggage, Finn; Medo, Matus; Basile, Giulia; Meise, Dominik F.; Zwyssig, Sandra; Wenger, Corina; Schwarz, Kyriakos; Vancura, Adrienne; Bosch-Guiteras, Nuria; Andrades, Alvaro; Tham, Ai Ming; Roemmele, Michaela; Ochsenbein, Adrian F.; Riether, Carsten; Kruithof-de Julio, Marianna; Zimmer, Yitzhak; Medova, Michaela; Stroka, Deborah; Fox, Archa; Johnson, Rory 分享 收藏
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MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Liang, Shun-Qing; Yang, Zhang; Scherz, Amina; Hall, Sean R. R.; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F. F.; Marti, Thomas M. M.; Kocher, Gregor J. J.; Schmid, Ralph A. A.; Dorn, Patrick; Peng, Ren-Wang 分享 收藏
Results from a phase I/II trial of cusatuzumab combined with azacitidine in patients with newly diagnosed acute myeloid leukemia who are ineligible for intensive chemotherapy Pabst, Thomas; Vey, Norbert; Ades, Lionel; Bacher, Ulrike; Bargetzi, Mario; Fung, Samson; Gaidano, Gianluca; Gandini, Domenica; Hultberg, Anna; Johnson, Amy; Ma, Xuewen; Muller, Rouven; Nottage, Kerri; Papayannidis, Cristina; Recher, Christian; Riether, Carsten; Shah, Priya; Tryon, Jeffrey; Xiu, Liang; Ochsenbein, Adrian F. 分享 收藏
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Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance Buhrer, Elias D.; Amrein, Michael A.; Forster, Stefan; Isringhausen, Stephan; Schuerch, Christian M.; Bhate, Salil S.; Brodie, Tess; Zindel, Joel; Stroka, Deborah; Al Sayed, Mohamad; Nombela-Arrieta, Cesar; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian F. 分享 收藏
Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+T cells with high functional and metabolic capacities Siglec-7代表具有高功能和代谢能力的非耗尽效应记忆CD8 T细胞的糖免疫检查点 Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M.; Ng, Charlotte K. Y.; Munz, Christian; Riether, Carsten; Ochsenbein, Adrian F.; Simon, Hans-Uwe; von Gunten, Stephan 分享 收藏
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Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities Esposito, Roberta; Polidori, Taisia; Meise, Dominik F.; Pulido-Quetglas, Carlos; Chouvardas, Panagiotis; Forster, Stefan; Schaerer, Paulina; Kobel, Andrea; Schlatter, Juliette; Kerkhof, Erik; Roemmele, Michaela; Rice, Emily S.; Zhu, Lina; Lanzos, Andrea; Guillen-Ramirez, Hugo A.; Basile, Giulia; Carrozzo, Irene; Vancura, Adrienne; Ullrich, Sebastian; Andrades, Alvaro; Harvey, Dylan; Medina, Pedro P.; Ma, Patrick C.; Haefliger, Simon; Wang, Xin; Martinez, Ivan; Ochsenbein, Adrian F.; Riether, Carsten; Johnson, Rory 分享 收藏
Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanova, Tereza; Urzi, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael 分享 收藏
Long-term outcomes of operable stage III NSCLC in the pre-immunotherapy era: results from a pooled analysis of the SAKK 16/96, SAKK 16/00, SAKK 16/01, and SAKK 16/08 trials (vol 7, 100455, 2022) Konig, D.; Schar, S.; Vuong, D.; Guckenberger, M.; Furrer, K.; Opitz, I.; Weder, W.; Rothschild, S. I.; Ochsenbein, A.; Zippelius, A.; Addeo, A.; Mark, M.; Eboulet, E. I.; Hayoz, S.; Thierstein, S.; Betticher, D. C.; Ris, H. -B.; Stupp, R.; Curioni-Fontecedro, A.; Peters, S.; Pless, M.; Fruh, M. 分享 收藏
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