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V

Vicki L. McGovern

the ohio state university wexner medical center

H指数:21

被引数:3,433

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Lack of sensorimotor toxicity when using the clinical SMN expression cassette in scAAV9

在scAAV9中使用临床SMN表达盒未见感觉运动毒性

Nature Neuroscience

IF20

2026-08-240

PRE

A Role for SMN Exon 7 Splicing in the Selective Vulnerability of Motor Neurons in Spinal Muscular Atrophy

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20107

OAAI

RETRACTION: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN (Retraction of Vol 28, Pg 271, 2010)

NATURE BIOTECHNOLOGY

IF41.7

2022-10-064

OA

Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic increment 7SMA mice

NEUROBIOLOGY OF DISEASE

IF5.6

2021-11-0119

OAAI

Biodistribution of onasemnogene abeparvovec DNA, mRNA and SMN protein in human tissue

NATURE MEDICINE

IF50

2021-10-0463

PREAI

Intragenic complementation of amino and carboxy terminal SMN missense mutations can rescue Smn null mice

HUMAN MOLECULAR GENETICS

IF3.2

2020-10-214

OAAI

Conditional deletion of SMN in cell culture identifies functional SMN alleles

HUMAN MOLECULAR GENETICS

IF3.2

2020-10-199

OAAI

Complete sequencing of the SMN2 gene in SMA patients detects SMN gene deletion junctions and variants in SMN2 that modify the SMA phenotype

IF3.6

2019-02-2065

OAAI

Mild SMN missense alleles are only functional in the presence of SMN2 in mammals

HUMAN MOLECULAR GENETICS

IF3.2

2018-08-1013

OAAI

Natural history of infantile-onset spinal muscular atrophy

ANNALS OF NEUROLOGY

IF7.7

2017-12-08297

OA

Kolb, Stephen J.; Coffey, Christopher S.; Yankey, Jon W.; Krosschell, Kristin; Arnold, W. David; Rutkove, Seward B.; Swoboda, Kathryn J.; Reyna, Sandra P.; Sakonju, Ai; Darras, Basil T.; Shell, Richard; Kuntz, Nancy; Castro, Diana; Parsons, Julie; Connolly, Anne M.; Chiriboga, Claudia A.; McDonald, Craig; Burnette, W. Bryan; Werner, Klaus; Thangarajh, Mathula; Shieh, Perry B.; Finanger, Erika; Cudkowicz, Merit E.; McGovern, Michelle M.; McNeil, D. Elizabeth; Finkel, Richard; Iannaccone, Susan T.; Kaye, Edward; Kingsley, Allison; Renusch, Samantha R.; McGovern, Vicki L.; Wang, Xueqian; Zaworski, Phillip G.; Prior, Thomas W.; Burghes, Arthur H. M.; Bartlett, Amy; Kissel, John T.

The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy

NEUROBIOLOGY OF DISEASE

IF5.6

2016-03-0146

OAAI

Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA

HUMAN MOLECULAR GENETICS

IF3.2

2015-08-1347

OAAI

SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice (vol 24, pg 3847, 2015)

HUMAN MOLECULAR GENETICS

IF3.2

2015-07-299

OAAI

SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA

HUMAN MOLECULAR GENETICS

IF3.2

2015-07-2356

OAAI

SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice

HUMAN MOLECULAR GENETICS

IF3.2

2015-04-0945

OAAI

Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose-response Study in Mice and Nonhuman Primates

MOLECULAR THERAPY

IF12

2015-03-01262

OAAI

Electrophysiological biomarkers in spinal muscular atrophy: proof of concept

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2013-12-0672

OAAI

A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse

HUMAN MOLECULAR GENETICS

IF3.2

2011-12-20243

OAAI

Temporal requirement for high SMN expression in SMA mice

HUMAN MOLECULAR GENETICS

IF3.2

2011-06-13124

OAAI

Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

HUMAN MOLECULAR GENETICS

IF3.2

2010-07-16200

OAAI