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D

David H. Lum

Huntsman Cancer Institute
H指数:20
被引数:3,638

个人简介

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工作经历

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荣誉奖项

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Preventing trogocytosis by cathepsin B inhibition augments CAR T-cell function

通过抑制组织蛋白酶B防止吞噬作用增强了CAR T细胞功能

Signal Transduction and Targeted Therapy
IF52.7
2026-04-220
OAAI
Kenneth A. Dietze; Kiet Nguyen; Aashli Pathni; Frank Fazekas; Wenxiang Sun; Ethan Rosati; Jillian M. Baker; Maday Galeana Figueroa; Etse Gebru; Daniel Yamoah; Rediet Mulatu; Alexander Wang; Aaron P. Rapoport; David H. Lum; Xiaoxuan Fan; Sabarinath V. Radhakrishnan; Djordje Atanackovic; Arpita Upadhyaya; Tim Luetkens
Identification and characterization of BRAF⇔TP53 interactions in melanoma

BRAF⇔TP53相互作用在黑色素瘤中的鉴定与表征

Cell Reports
IF6.9
2026-03-200
OAAI
Kayla T. O’Toole; Adamaris Martinez; Brandon Murphy; Gabriela Fort; Fatima Al-Sudani; Anastasia Prokofyeva; Sanjana Boggaram; Eric A. Smith; Elliott L. Paine; Deevya Baral; David Lum; Wei Zhang; Erika Egal; Gennie L. Parkman; Eric L. Snyder; Robert Judson-Torres; Joshua L. Andersen; Martin McMahon
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers (vol 25, pg 620, 2019)

RAF→MEK→ERK抑制所诱发的保护性自噬表明了一种针对RAS驱动型癌症的治疗策略（卷25，页620，2019）

NATURE MEDICINE
IF50
2025-04-250
PRE
Kinsey, Conan G.; Camolotto, Soledad A.; Boespflug, Amelie M.; Guillen, Katrin P.; Foth, Mona; Truong, Amanda; Schuman, Sophia S.; Shea, Jill E.; Seipp, Michael T.; Yap, Jeffrey T.; Burrell, Lance D.; Lum, David H.; Whisenant, Jonathan R.; Gilcrease III, G. Weldon; Cavalieri, Courtney C.; Rehbein, Kaitrin M.; Cutler, Stephanie L.; Affolter, Kajsa E.; Welm, Alana L.; Welm, Bryan E.; Scaife, Courtney L.; Snyder, Eric L.; McMahon, Martin
Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2024-12-030
OAAI
Smith, Eric A.; Belote, Rachel L.; Cruz, Nelly M.; Moustafa, Tarek E.; Becker, Carly A.; Jiang, Amanda; Alizada, Shukran; Prokofyeva, Anastasia; Chan, Tsz Yin; Seasor, Tori A.; Balatico, Michael; Cortes-Sanchez, Emilio; Lum, David H.; Hyngstrom, John R.; Zeng, Hanlin; Deacon, Dekker C.; Grossmann, Allie H.; White, Richard M.; Zangle, Thomas A.; Judson-Torres, Robert L.
Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma
CANCER RESEARCH
IF16.6
2023-09-273
OAAI
Wu, Yige; Chen, Siqi; Yang, Xiaolu; Sato, Kazuhito; Lal, Preet; Wang, Yuefan; Shinkle, Andrew T.; Wendl, Michael C.; Primeau, Tina M.; Zhao, Yanyan; Gould, Alanna; Sun, Hua; Mudd, Jacqueline L.; Hoog, Jeremy; Mashl, R. Jay; Wyczalkowski, Matthew A.; Mo, Chia-Kuei; Liu, Ruiyang; Herndon, John M.; Davies, Sherri R.; Liu, Di; Ding, Xi; Evrard, Yvonne A.; Welm, Bryan E.; Lum, David; Koh, Mei Yee; Welm, Alana L.; Chuang, Jeffrey H.; Moscow, Jeffrey A.; Meric-Bernstam, Funda; Govindan, Ramaswamy; Li, Shunqiang; Hsieh, James; Fields, Ryan C.; Lim, Kian-Huat; Ma, Cynthia X.; Zhang, Hui; Ding, Li; Chen, Feng
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

用于药物发现和精确肿瘤学的人类乳腺癌衍生异种移植物和类器官平台

NATURE CANCER
IF28.5
2022-02-24184
OAAI
Guillen, Katrin P.; Fujita, Maihi; Butterfield, Andrew J.; Scherer, Sandra D.; Bailey, Matthew H.; Chu, Zhengtao; DeRose, Yoko S.; Zhao, Ling; Cortes-Sanchez, Emilio; Yang, Chieh-Hsiang; Toner, Jennifer; Wang, Guoying; Qiao, Yi; Huang, Xiaomeng; Greenland, Jeffery A.; Vahrenkamp, Jeffery M.; Lum, David H.; Factor, Rachel E.; Nelson, Edward W.; Matsen, Cindy B.; Poretta, Jane M.; Rosenthal, Regina; Beck, Anna C.; Buys, Saundra S.; Vaklavas, Christos; Ward, John H.; Jensen, Randy L.; Jones, Kevin B.; Li, Zheqi; Oesterreich, Steffi; Dobrolecki, Lacey E.; Pathi, Satya S.; Woo, Xing Yi; Berrett, Kristofer C.; Wadsworth, Mark E.; Chuang, Jeffrey H.; Lewis, Michael T.; Marth, Gabor T.; Gertz, Jason; Varley, Katherine E.; Welm, Bryan E.; Welm, Alana L.
Protective autophagy elicited by RAF®MEK®ERK inhibition suggests a treatment strategy for pancreatic cancer
CANCER RESEARCH
IF16.6
2019-07-010
PRE
Kinsey, Conan G.; Camolotto, Soledad A.; Boespflug, Amelie M.; Guillen, Katrin P.; Foth, Mona; Truong, Amanda; Schuman, Sophia S.; Shea, Jill E.; Seipp, Michael T.; Yap, Jeffrey T.; Burrell, Lance D.; Lum, David H.; Whisenant, Jonathan R.; Gilcrease, G. Weldon; Cavalieri, Courtney C.; Rehbein, Kaitrin M.; Cutler, Stephanie L.; Affolter, Kajsa E.; Welm, Alana L.; Welm, Bryan E.; Scaife, Courtney L.; Snyder, Eric L.; McMahon, Martin
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers (vol 25, pg 620, 2019)
NATURE MEDICINE
IF50
2019-03-2719
OAAI
Kinsey, Conan G.; Camolotto, Soledad A.; Boespflug, Amelie M.; Guillen, Katrin P.; Foth, Mona; Truong, Amanda; Schuman, Sophia S.; Shea, Jill E.; Seipp, Michael T.; Yap, Jeffrey T.; Burrell, Lance D.; Lum, David H.; Whisenant, Jonathan R.; Gilcrease, G. Weldon, III; Cavalieri, Courtney C.; Rehbein, Kaitrin M.; Cutler, Stephanie L.; Affolter, Kajsa E.; Welm, Alana L.; Welm, Bryan E.; Scaife, Courtney L.; Snyder, Eric L.; McMahon, Martin
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Raf → mek → erk抑制引起的保护性自噬提示RAS驱动的癌症的治疗策略

NATURE MEDICINE
IF50
2019-03-04500
OAAI
Kinsey, Conan G.; Camolotto, Soledad A.; Boespflug, Amelie M.; Guillen, Katrin P.; Foth, Mona; Truong, Amanda; Schuman, Sophia S.; Shea, Jill E.; Seipp, Michael T.; Yap, Jeffrey T.; Burrell, Lance D.; Lum, David H.; Whisenant, Jonathan R.; Gilcrease, G. Weldon, III; Cavalieri, Courtney C.; Rehbein, Kaitrin M.; Cutler, Stephanie L.; Affolter, Kajsa E.; Welm, Alana L.; Welm, Bryan E.; Scaife, Courtney L.; Snyder, Eric L.; McMahon, Martin

研究方向

暂未获取到该数据
A
Alana L. Welm
H 指数:52论文数:496被引数:1.2万
M
Martin McMahon
H 指数:79论文数:543被引数:2.3万
B
Bryan E. Welm
H 指数:29论文数:254被引数:5,699
M
Mona Foth
H 指数:12论文数:58被引数:1,951
E
Eric L. Snyder
H 指数:30论文数:130被引数:5,968
K
Katrin P. Guillen
H 指数:12论文数:56被引数:1,391
J
Jill Shea
H 指数:23论文数:106被引数:4,002
A
Amélie Boespflug
H 指数:13论文数:53被引数:1,329
J
Jeffrey T. Yap
H 指数:35论文数:167被引数:6,770
C
Conan G. Kinsey
H 指数:12论文数:81被引数:3,754