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Phase 2 trial of imprime and pembrolizumab immunotherapy in metastatic triple negative breast cancer patients who have progressed beyond first line chemotherapy 二线化疗进展后的转移性三阴性乳腺癌患者中Imprime与Pembrolizumab免疫疗法的二期临床试验 Stopeck, Alison T.; Abu-Khalaf, Maysa; Borges, Virginia; Chmielowski, Bartosz; Rao, Ruta; Xie, Bin; Dudek, Arkadiusz Z.; Mina, Lida; O'Shaughnessy, Joyce; Chisamore, Michael; Mattson, Paulette; Gargano, Michele; Cox, Joanna; Osterwalder, Bruno; Drees, Jeremy; Harrison, Ben; Chan, Anissa S. H.; Qiu, Xiaohong; Ottoson, Nadine; Bose, Nandita; Uhlik, Mark; Graff, Jeremy; Iglesias, Jose 分享 收藏
Cancer Surveillance in Solid Organ Transplant Recipients With a Pretransplant History of Malignancy: Multidisciplinary Collaborative Expert Opinion Watt, Kymberly D.; Rolak, Stacey; Foley, David P.; Plichta, Jennifer K.; Pruthi, Sandhya; Farr, Deborah; Zwald, Fiona O.; Carvajal, Richard D.; Dudek, Arkadiusz Z.; Sanger, Cristina B.; Rocco, Ricciardi; Chang, George J.; Dizon, Don S.; Langstraat, Carrie L.; Teoh, Deanna; Agarwal, Piyush K.; Al-Qaoud, Talal; Eggener, Scott; Kennedy, Cassie C.; D'Cunha, Jonathan; Mohindra, Nisha A.; Stewart, Shelby; Habermann, Thomas H.; Schuster, Stephen; Lunning, Matthew; Shah, Nirav N.; Gertz, Morie A.; Mehta, Jayesh; Suvannasankha, Attaya; Verna, Elizabeth; Farr, Maryjane; Blosser, Christopher D.; Hammel, Laura; Al-Adra, David P. 分享 收藏
Phase 1 trial of MEK1 inhibitor E6201 plus dabrafenib in patients (pts) with BRAF V600-mutated metastatic melanoma (MM) with central nervous system (CNS) metastases (mets) Seetharam, Mahesh; Dronca, Roxana; Dudek, Arkadiusz Z.; Nelson, Garth; Block, Matthew; Starling, Skylar; Baskin, Amber; Bradshaw, Renee; Nelson, Courtney; Andrews, Kylee; Birgin, Alisha; Watson, Cristina; Yan, Yiyi; Mahadevan, Daruka; Markovic, Svetomir; Myers, Tom; Paradiso, Linda; Babiker, Hani 分享 收藏
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Intrinsic endothelial hyperresponsiveness to inflammatory mediators drives acute episodes in models of Clarkson disease Ablooglu, Ararat J.; Chen, Wei-Sheng; Xie, Zhihui; Desai, Abhishek; Paul, Subrata; Lack, Justin B.; Scott, Linda A.; Eisch, Robin; Dudek, Arkadiusz Z.; Parikh, Samir M.; Druey, Kirk M. 分享 收藏
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A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses Smith, Katherine E. R.; Peng, Kah-Whye; Pulido, Jose S.; Weisbrod, Adam J.; Strand, Carrie A.; Allred, Jacob B.; Newsom, Alysha N.; Zhang, Lianwen; Packiriswamy, Nandakumar; Kottke, Timothy; Tonne, Jason M.; Moore, Madelyn; Montane, Heather N.; Kottschade, Lisa A.; McWilliams, Robert R.; Dudek, Arkadiusz Z.; Yan, Yiyi; Dimou, Anastasios; Markovic, Svetomir N.; Federspiel, Mark J.; Vile, Richard G.; Dronca, Roxana S.; Block, Matthew S. 分享 收藏
Phase I dose-escalation study of procaspase-activating compound-1 in combination with temozolomide in patients with recurrent high-grade astrocytomas Holdhoff, Matthias; Nicholas, M. Kelly; Peterson, Richard A.; Maraka, Stefania; Liu, Li C.; Fischer, James H.; Wefel, Jeffrey S.; Fan, Timothy M.; Vannorsdall, Tracy; Russell, Meredith; Iacoboni, Michaella; Tarasow, Theodore M.; Hergenrother, Paul J.; Dudek, Arkadiusz Z.; Danciu, Oana C. 分享 收藏
Ral Overactivation in Malignant Peripheral Nerve Sheath Tumors 恶性周围神经鞘瘤的Ral过度激活 Bodempudi, Vidya; Yamoutpoor, Farnaz; Pan, Weihong; Dudek, Arkadiusz Z.; Esfandyari, Tuba; Piedra, Mark; Babovick-Vuksanovic, Dusica; Woo, Richard A.; Mautner, Victor F.; Kluwe, Lan; Clapp, D. Wade; DeVries, George H.; Thomas, Stacey L.; Kurtz, Andreas; Parada, Luis F.; Farassati, Faris 分享 收藏
Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies procaspase激活化合物-1 (PAC-1) 治疗晚期恶性肿瘤的I期研究 Danciu, Oana C. C.; Holdhoff, Matthias; Peterson, Richard A. A.; Fischer, James H. H.; Liu, Li C. C.; Wang, Heng; Venepalli, Neeta K. K.; Chowdhery, Rozina; Nicholas, M. Kelly; Russell, Meredith J. J.; Fan, Timothy M. M.; Hergenrother, Paul J. J.; Tarasow, Theodore M. M.; Dudek, Arkadiusz Z. Z. 分享 收藏
Markers of endothelial glycocalyx dysfunction in Clarkson disease Clarkson病内皮糖萼功能障碍的标志物 Xie, Zhihui; Borset, Magne; Sveen, Kjell; Boe, Ole Wilhelm; Chan, Eunice C.; Lack, Justin B.; Hornick, Katherine M.; Verlicchi, Franco; Eisch, A. Robin; Melchio, Remo; Dudek, Arkadiusz Z.; Druey, Kirk M. 分享 收藏
ARRY-382 in Combination with Pembrolizumab in Patients with Advanced Solid Tumors: Results from a Phase 1b/2 Study 晚期实体瘤患者与Pembrolizumab联合ARRY-382: 1b/2期研究的结果 Johnson, Melissa; Dudek, Arkadiusz Z.; Sukari, Ammar; Call, Justin; Kunk, Paul R.; Lewis, Karl; Gainor, Justin F.; Sarantopoulos, John; Lee, Patrice; Golden, Adele; Harney, Allison; Rothenberg, S. Michael; Zhang, Yuanyuan; Goldman, Jonathan W. 分享 收藏
FIRST-IN-HUMAN PHASE 1/2 STUDY OF THE FIRST-IN-CLASS SUMO-ACTIVATING ENZYME INHIBITOR TAK-981 IN PATIENTS WITH ADVANCED OR METASTATIC SOLID TUMORS OR RELAPSED/REFRACTORY LYMPHOMA: PHASE 1 RESULTS 首次在晚期或转移性实体瘤或复发/难治性淋巴瘤患者中TAK-981 SUMO激活酶抑制剂的人类1/2期研究: 1期结果 Dudek, Arkadiusz; Juric, Dejan; Dowlati, Afshin; Vaishampayan, Ulka; Assad, Hadeel; Rodon, Jordi; Chao, Bo; Wang, Bingxia; Gibbs, John; Shinde, Vaishali; Friedlander, Sharon; Berger, Allison; Ward, Christine; Martinez, Alonzo; Gharavi, Robert; Gomez-Pinillos, Alejandro; Proscurshim, Igor; Olszanski, Anthony 分享 收藏
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial Durvalumab联合铂类培美曲塞治疗不可切除的胸膜间皮瘤: PrE0505 2期临床试验的生存、基因组和免疫学分析 Forde, Patrick M.; Anagnostou, Valsamo; Sun, Zhuoxin; Dahlberg, Suzanne E.; Kindler, Hedy L.; Niknafs, Noushin; Purcell, Thomas; Santana-Davila, Rafael; Dudek, Arkadiusz Z.; Borghaei, Hossein; Lanis, Mara; Belcaid, Zineb; Smith, Kellie N.; Balan, Archana; White, James R.; Cherry, Christopher; Sivakumar, I. K. Ashok; Shao, Xiaoshan M.; Chan, Hok Yee; Singh, Dipika; Thapa, Sampriti; Illei, Peter B.; Pardoll, Drew M.; Karchin, Rachel; Velculescu, Victor E.; Brahmer, Julie R.; Ramalingam, Suresh S. 分享 收藏
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ARTISTRY-6: Nemvaleukin alfa monotherapy in patients with advanced mucosal and cutaneous melanoma Carvajal, R. D.; Weber, J. S.; Dudek, A. Z.; Grewal, J.; Mehmi, I.; Hamid, O.; Du, Y.; Desai, M.; Wang, Y.; Sun, L.; Rege, J.; Middleton, M. R. 分享 收藏
Alliance Foundation Trial 09: A Randomized, Multicenter, Phase 2 Trial Evaluating Two Sequences of Pembrolizumab and Standard Platinum-Based Chemotherapy in Patients With Metastatic NSCLC Alliance Foundation试验09: 一项随机，多中心，2期试验，评估了转移性NSCLC患者的两种Pembrolizumab和标准铂类化疗的两个序列 Hensing, Thomas A.; Wang, Xiaofei; Stinchcombe, Thomas E.; Gao, Junheng; V. Knopp, Michael; Watson, Mark; Dudek, Arkadiusz Z.; Graziano, Stephen L.; Patel, Jyoti D.; Faller, Bryan A.; Dragnev, Konstantin H.; Kozono, David; Faller, Bryan; Vokes, Everett E. 分享 收藏
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