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APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology APOE Christchurch增强了与疾病相关的小胶质细胞对斑块的反应，但抑制了对tau病理的反应 Tran, Kristine M.; Kwang, Nellie E.; Butler, Claire A.; Gomez-Arboledas, Angela; Kawauchi, Shimako; Mar, Cassandra; Chao, Donna; Barahona, Rocio A.; Da Cunha, Celia; Tsourmas, Kate I.; Shi, Zechuan; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Alcantara, Joshua A.; Neumann, Jonathan; Duong, Duc M.; Seyfried, Nicholas T.; Tenner, Andrea J.; Laferla, Frank M.; Hohsfield, Lindsay A.; Swarup, Vivek; Macgregor, Grant R.; Green, Kim N. 分享 收藏
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's disease 阿尔茨海默氏病遗传和散发性形式的空间和单核转录组学分析 Miyoshi, Emily; Morabito, Samuel; Henningfield, Caden M.; Das, Sudeshna; Rahimzadeh, Negin; Shabestari, Sepideh Kiani; Michael, Neethu; Emerson, Nora; Reese, Fairlie; Shi, Zechuan; Cao, Zhenkun; Srinivasan, Shushrruth Sai; Scarfone, Vanessa M.; Arreola, Miguel A.; Lu, Jackie; Wright, Sierra; Silva, Justine; Leavy, Kelsey; Lott, Ira T.; Doran, Eric; Yong, William H.; Shahin, Saba; Perez-Rosendahl, Mari; Alzheimers Biomarkers Consortium Down Syndrome ABC DS, Elizabeth; Head, Elizabeth; Green, Kim N.; Swarup, Vivek 分享 收藏
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BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease Garcia-Agudo, Laura Fernandez; Shi, Zechuan; Smith, Ian F.; Kramar, Eniko A.; Tran, Katelynn; Kawauchi, Shimako; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Liang, Heidi Yahan; Da Cunha, Celia; Milinkeviciute, Giedre; Morabito, Samuel; Miyoshi, Emily; Rezaie, Narges; Gomez-Arboledas, Angela; Arvilla, Adrian Mendoza; Ghaemi, Daryan Iman; Tenner, Andrea J.; LaFerla, Frank M.; Wood, Marcelo A.; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N. 分享 收藏
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease Soni, Neelakshi; Hohsfield, Lindsay A.; Tran, Kristine M.; Kawauchi, Shimako; Walker, Amber; Javonillo, Dominic; Phan, Jimmy; Matheos, Dina; Da Cunha, Celia; Uyar, Asli; Milinkeviciute, Giedre; Gomez-Arboledas, Angela; Tran, Katelynn; Kaczorowski, Catherine C.; Wood, Marcelo A.; Tenner, Andrea J.; LaFerla, Frank M.; Carter, Gregory .; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N. 分享 收藏
Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice Childs, Jessica E.; Morabito, Samuel; Das, Sudeshna; Santelli, Caterina; Pham, Victoria; Kusche, Kelly; Vera, Vanessa Alizo; Reese, Fairlie; Campbell, Rianne R.; Matheos, Dina P.; Swarup, Vivek; Wood, Marcelo A. 分享 收藏
Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma 复发性高级别胶质瘤非增强区的单核表达特征 Patel, Kunal S.; Tessema, Kaleab K.; Kawaguchi, Riki; Dudley, Lindsey; Alvarado, Alvaro G.; Muthukrishnan, Sree Deepthi; Perryman, Travis; Hagiwara, Akifumi; Swarup, Vivek; Liau, Linda M.; Wang, Anthony C.; Yong, William; Geschwind, Daniel H.; Nakano, Ichiro; Goldman, Steven A.; Everson, Richard G.; Ellingson, Benjamin M.; Kornblum, Harley, I 分享 收藏
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A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques 没有隐性剪接的Trem2R47H小鼠模型驱动年龄和疾病依赖性组织损伤和响应于斑块的突触丢失 Tran, Kristine M. M.; Kawauchi, Shimako; Kramar, Eniko A.; Rezaie, Narges; Liang, Heidi Yahan; Sakr, Jasmine S. S.; Gomez-Arboledas, Angela; Arreola, Miguel A. A.; da Cunha, Celia; Phan, Jimmy; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Filimban, Ghassan; Shi, Zechuan; Milinkeviciute, Giedre; Javonillo, Dominic I. I.; Tran, Katelynn; Gantuz, Magdalena; Forner, Stefania; Swarup, Vivek; Tenner, Andrea J. J.; LaFerla, Frank M. M.; Wood, Marcelo A. A.; Mortazavi, Ali; MacGregor, Grant R. R.; Green, Kim N. N. 分享 收藏
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation Lim, Ryan G.; Al-Dalahmah, Osama; Wu, Jie; Gold, Maxwell P.; Reidling, Jack C.; Tang, Guomei; Adam, Miriam; Dansu, David K.; Park, Hye-Jin; Casaccia, Patrizia; Miramontes, Ricardo; Reyes-Ortiz, Andrea M.; Lau, Alice; Hickman, Richard A.; Khan, Fatima; Paryani, Fahad; Tang, Alice; Ofori, Kenneth; Miyoshi, Emily; Michael, Neethu; McClure, Nicolette; Flowers, Xena E.; Vonsattel, Jean Paul; Davidson, Shawn; Menon, Vilas; Swarup, Vivek; Fraenkel, Ernest; Goldman, James E.; Thompson, Leslie M. 分享 收藏
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease Otero-Garcia, Marcos; Mahajani, Sameehan U.; Wakhloo, Debia; Tang, Weijing; Xue, Yue-Qiang; Morabito, Samuel; Pan, Jie; Oberhauser, Jane; Madira, Angela E.; Shakouri, Tamara; Deng, Yongning; Allison, Thomas; He, Zihuai; Lowry, William E.; Kawaguchi, Riki; Swarup, Vivek; Cobos, Inma 分享 收藏
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice Shabestari, Sepideh Kiani; Morabito, Samuel; Danhash, Emma Pascal; McQuade, Amanda; Sanchez, Jessica Ramirez; Miyoshi, Emily; Chadarevian, Jean Paul; Claes, Christel; Coburn, Morgan Alexandra; Hasselmann, Jonathan; Hidalgo, Jorge; Tran, Kayla Nhi; Martini, Alessandra C.; Rothermich, Winston Chang; Pascual, Jesse; Head, Elizabeth; Hume, David A.; Pridans, Clare; Davtyan, Hayk; Swarup, Vivek; Blurton-Jones, Mathew 分享 收藏
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