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M

Marieke van de Ven

the netherlands cancer institute
H指数:32
被引数:7,371

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A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

全基因组CRISPR筛选在人前列腺癌细胞中揭示了巨噬细胞介导的细胞杀伤的驱动因子，并将AR定位为肿瘤内源性免疫调节因子

Oncogene
IF7.3
2026-07-280
PRE
Anniek Zaalberg; Audrey Lacoste; Emma Minnee; Isabel Mayayo-Peralta; Karianne Schuurman; Sebastian Gregoricchio; Thijs A. van Schaik; Liesbeth Hoekman; Dapei Li; Eva Corey; Hans Janssen; Cor Lieftink; Stefan Prekovic; Natalie Proost; Marieke van de Ven; Serge Zander; Maarten Altelaar; Peter S. Nelson; Roderick L. Beijersbergen; Wilbert Zwart; Andries M. Bergman
MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors

MDC1拮抗复制叉逆转并介导BRCA1/2缺陷型肿瘤的化疗敏感性

Oncogene
IF7.3
2025-12-170
OAAI
Hülya Dogan; Martin Liptay; Joana S. Barbosa; Ewa Gogola; Alexandra A. Duarte; Jonas A. Schmid; Ismar Klebic; Merve Mutlu; Myriam Siffert; Paola Francica; Israel Salguero; Marieke van de Ven; Renske de Korte-Grimmerink; Stephen P. Jackson; Jos Jonkers; Massimo Lopes; Diego Dibitetto; Sven Rottenberg
A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution

一种用于冻存啮齿类疾病模型的质控框架：INFRAFRONTIER在EMMA归档和分发中的质量原则

Mammalian Genome
IF2.7
2025-12-100
OAAI
Hilke Ehlich; Andrew Blease; Reva Biju; Montse Gustems; Fei Song; Sabine Fessele; Marzia Massimi; Konstantinos Bozonelos; Vasileios Ntafis; Anniina E. Hiltunen; Susan Marschall; Claudia Stoeger; Zuzana Khorshidi; Abdelmalek Ziadi; Karine Jambou; Arsenio Armagno; Ferdinando Scavizzi; Marcello Raspa; Julia Fernandez; María Jesús del Hierro; Abdelkader Ayadi; Joelle Pensavalle; Géraldine Prevost; Lucie Dufková; Michaela Krupkova; Petr Nickl; Paul Krimpenfort; Marieke van de Ven; Jos Jonkers; Gema Valera Vázquez; Michael Raess; Johannes Beckers; Anna Moles; Maik Dahlhoff; Lluis Montoliu; Yann Hérault; Reetta Hinttala; Dimitris L. Kontoyiannis; Radislav Sedlacek; Martin Hrabě de Angelis; Auke A. Boersma; Rafaele Matteoni
NASP modulates histone turnover to drive PARP inhibitor resistance

NASP通过调节组蛋白周转来驱动PARP抑制剂耐药性。

Nature
IF48.5
2025-08-130
PRE
Sarah C. Moser; Anna Khalizieva; Josef Roehsner; Elisabeth Pottendorfer; Milo L. Kaptein; Giulia Ricci; Vivek Bhardwaj; Onno B. Bleijerveld; Liesbeth Hoekman; Ingrid van der Heijden; Simone di Sanzo; Alexander Fish; Aleksandra Chikunova; Judith H. I. Haarhuis; Roel Oldenkamp; Luisa Robbez-Masson; Justin Sprengers; Daniel J. Vis; Lodewyk F. A. Wessels; Marieke van de Ven; Stephen J. Pettitt; Andrew N. J. Tutt; Christopher J. Lord; Benjamin D. Rowland; Moritz Völker-Albert; Francesca Mattiroli; Thijn R. Brummelkamp; Abdelghani Mazouzi; Jos Jonkers
Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers

二磷酸胞苷二酰基甘油合酶2是间质样癌症中的合成致死靶点

Nature Genetics
IF0
2025-07-040
OA
Tim Arnoldus; Alex van Vliet; Onno B. Bleijerveld; Adriaan F. H. de Groot; Qinglin Piao; Niek Blomberg; Désirée Schatton; Jing Dong; Susan E. van Hal-van Veen; Rolf Harkes; Anita E. Grootemaat; Natalie Proost; Birol Cabukusta; Christian Frezza; Marieke van de Ven; Nicole N. van der Wel; Martin Giera; Maarten Altelaar; Daniel S. Peeper
Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation

靶向可诱导且广泛共享的异常mRNA翻译产物的T细胞疗法

IMMUNITY
IF26.3
2025-01-011
OAAI
Champagne, Julien; Nielsen, Morten M.; Feng, Xiaodong; Navarro, Jasmine Montenegro; Pataskar, Abhijeet; Voogd, Rhianne; Giebel, Lisanne; Nagel, Remco; Berenst, Nadine; Fumagalli, Amos; Kochavi, Adva; Lovecchio, Domenica; Valcanover, Lorenzo; Malka, Yuval; Yang, Weiwen; Laos, Maarja; Li, Yingqian; Proost, Natalie; van de Ven, Marieke; van Tellingen, Olaf; Bleijerveld, Onno B.; Haanen, John B. A. G.; Olweus, Johanna; Agami, Reuven
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer

MYC是乳腺癌中mTOR抑制剂耐药的临床重要驱动因素

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2023-08-291
OAAI
Bhin, Jinhyuk; Yemelyanenko, Julia; Chao, Xue; Klarenbeek, Sjoerd; Opdam, Mark; Malka, Yuval; Hoekman, Liesbeth; Kruger, Dinja; Bleijerveld, Onno; Brambillasca, Chiara S.; Sprengers, Justin; Siteur, Bjorn; Annunziato, Stefano; van Haren, Matthijs J.; Martin, Nathaniel I.; van de Ven, Marieke; Peters, Dennis; Agami, Reuven; Linn, Sabine C.; Boven, Epie; Altelaar, Maarten; Jonkers, Jos; Zingg, Daniel; Wessels, Lodewyk F. A.
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1-versus BRCA2-deficient mammary tumors
CELL REPORTS
IF6.9
2023-05-0116
OAAI
Bhin, Jinhyuk; Dias, Mariana Paes; Gogola, Ewa; Rolfs, Frank; Piersma, Sander R.; de Bruijn, Roebi; de Ruiter, Julian R.; van den Broek, Bram; Duarte, Alexandra A.; Sol, Wendy; van der Heijden, Ingrid; Andronikou, Christina; Kaiponen, Taina S.; Bakker, Lara; Lieftink, Cor; Morris, Ben; Beijersbergen, Roderick L.; van de Ven, Marieke; Jimenez, Connie R.; Wessels, Lodewyk F. A.; Rottenberg, Sven; Jonkers, Jos
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

MYC通过抑制干扰素信号促进三阴性乳腺癌的免疫抑制

NATURE COMMUNICATIONS
IF15.7
2022-11-0245
OAAI
Zimmerli, Dario; Brambillasca, Chiara S.; Talens, Francien; Bhin, Jinhyuk; Linstra, Renske; Romanens, Lou; Bhattacharya, Arkajyoti; Joosten, Stacey E. P.; Da Silva, Ana Moises; Padrao, Nuno; Wellenstein, Max D.; Kersten, Kelly; de Boo, Mart; Roorda, Maurits; Henneman, Linda; de Bruijn, Roebi; Annunziato, Stefano; van der Burg, Eline; Drenth, Anne Paulien; Lutz, Catrin; Endres, Theresa; van de Ven, Marieke; Eilers, Martin; Wessels, Lodewyk; de Visser, Karin E.; Zwart, Wilbert; Fehrmann, Rudolf S. N.; van Vugt, Marcel A. T. M.; Jonkers, Jos
Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical for KRAS mutant cancer
CELL REPORTS MEDICINE
IF10.6
2022-11-0122
OAAI
Frank, Katrin J.; Mulero-Sanchez, Antonio; Berninger, Alexandra; Ruiz-Canas, Laura; Bosma, Astrid; Gorgulu, Kivanc; Wu, Nan; Diakopoulos, Kalliope N.; Kaya-Aksoy, Ezgi; Ruess, Dietrich A.; Kabacaoglu, Derya; Schmidt, Franze; Kohlmann, Larissa; van Tellingen, Olaf; Thijssen, Bram; van de Ven, Marieke; Proost, Natalie; Kossatz, Susanne; Weber, Wolfgang A.; Sainz Jr, Bruno; Bernards, Rene; Algul, Hana; Lesina, Marina; Mainardi, Sara
Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine
NUCLEIC ACIDS RESEARCH
IF13.1
2022-07-127
OAAI
Spanjaard, Aldo; Shah, Ronak; de Groot, Daniel; Buoninfante, Olimpia Alessandra; Morris, Ben; Lieftink, Cor; Pritchard, Colin; Zurcher, Lisa M.; Ormel, Shirley; Catsman, Joyce J., I; De Korte-Grimmerink, Renske; Siteur, Bjorn; Proost, Natalie; Boadum, Terry; van de Ven, Marieke; Song, Ji-Ying; Kreft, Maaike; van den Berk, Paul C. M.; Beijersbergen, Roderick L.; Jacobs, Heinz

研究方向

暂未获取到该数据
J
Jos Jonkers
H 指数:109论文数:920被引数:5.4万
N
Natalie Proost
H 指数:25论文数:139被引数:4,836
S
Stefano Annunziato
H 指数:23论文数:106被引数:2,714
J
Jos Jonkers
H 指数:0论文数:5被引数:8
S
Sven Rottenberg
H 指数:48论文数:298被引数:1.4万
L
Lodewyk F.A. Wessels
H 指数:89论文数:1,030被引数:4.7万
P
Peter Bouwman
H 指数:31论文数:165被引数:6,860
J
Jinhyuk Bhin
H 指数:26论文数:98被引数:2,391
C
Catrin Lutz
H 指数:12论文数:87被引数:788
S
Sjoerd Klarenbeek
H 指数:22论文数:167被引数:1,944