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P

Peter Bouwman

Leiden University
H指数:31
被引数:6,860

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A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation

使用肝、肾和心脏hiPSC-ICAM1-eGFP报告细胞系进行广谱激酶抑制剂库的活细胞成像筛选，以识别TNFα通路调控的缺陷。

Archives of Toxicology
IF6.9
2025-11-050
OAAI
Matthijs Vlasveld; Linda van den Berk; Janet Piñero; Palle S. Helmke; Gerhard F. Ecker; Rob van Rossom; Bela Z. Schmidt; Catherine Verfaillie; Konstantinos Tassis; Giulia Callegaro; Peter Bouwman; Bob van de Water
Mathematical modelling reveals compound-specific stress pathway activity

数学建模揭示了化合物特异性的应激通路活性

Toxicology
IF4.6
2025-07-300
OAAI
Elsje J. Burgers; Tamara Y. Danilyuk; Raju P. Sharma; Nadine Renner; Andreas Verlohner; Nicole Rocker; Philipp Ternes; Lukas S. Wijaya; Marcel Leist; Peter Bouwman; Franziska M. Zickgraf; Stefan Schildknecht; Bob van de Water; Joost B. Beltman
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project
FRONTIERS IN TOXICOLOGY
IF4.6
2023-07-107
OAAI
Audebert, Marc; Assmann, Ann-Sophie; Azqueta, Amaya; Babica, Pavel; Benfenati, Emilio; Bortoli, Sylvie; Bouwman, Peter; Braeuning, Albert; Burgdorf, Tanja; Coumoul, Xavier; Debizet, Kloe; Dusinska, Maria; Ertych, Norman; Fahrer, Joerg; Fetz, Verena; Le Hegarat, Ludovic; de Cerain, Adela Lopez; Heusinkveld, Harm J.; Hogeveen, Kevin; Jacobs, Miriam N.; Luijten, Mirjam; Raitano, Giuseppa; Recoules, Cynthia; Runden-Pran, Elise; Saleh, Mariam; Sovadinova, Iva; Stampar, Martina; Thibol, Lea; Tomkiewicz, Celine; Vettorazzi, Ariane; van de Water, Bob; El Yamani, Naouale; Zegura, Bojana; Oelgeschlaeger, Michael
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

Autotaxin是一种分泌的溶血磷脂酶D，对于发育过程中的血管形成至关重要

MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-27509
OAAI
van Meeteren, Laurens A.; Ruurs, Paula; Stortelers, Catelijne; Bouwman, Peter; van Rooijen, Marga A.; Pradere, Jean Philippe; Pettit, Trevor R.; Wakelam, MiChael J. O.; Saulnier-Blache, Jean Sebastien; Mummery, Christine L.; Moolenaar, Wouter H.; Jonkers, Jos
Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays (vol 26, pg 4559, 2020)

在同源重组修复互补测定中临床意义不确定的BRCA1变体的功能分类 (第26卷，4559页，2020)

CLINICAL CANCER RESEARCH
IF10.2
2022-10-140
OA
Bouwman, Peter; van der Heijden, Ingrid; van der Gulden, Hanneke; de Bruijn, Roebi; Braspenning, Merel E.; Moghadasi, Setareh; Wessels, Lodewyk F. A.; Vreeswijk, Maaike P. G.; Jonkers, Jos
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer

EZH2和ATM的联合抑制在BRCA1-deficient乳腺癌中是合成致死的

BREAST CANCER RESEARCH
IF5.6
2022-06-177
OAAI
Ratz, Leonie; Brambillasca, Chiara; Bartke, Leandra; Huetzen, Maxim A.; Goergens, Jonas; Leidecker, Orsolya; Jachimowicz, Ron D.; van de Ven, Marieke; Proost, Natalie; Siteur, Bjorn; de Korte-Grimmerink, Renske; Bouwman, Peter; Pulver, Emilia M.; de Bruijn, Roebi; Isensee, Joerg; Hucho, Tim; Pandey, Gaurav; van Lohuizen, Maarten; Mallmann, Peter; Reinhardt, Hans Christian; Jonkers, Jos; Puppe, Julian
A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

破坏PALB2相互作用的BRCA1卷曲螺旋结构域变体促进乳腺肿瘤的发展，并在同源重组修复中赋予可靶向的缺陷

CANCER RESEARCH
IF16.6
2021-12-157
OA
Pulver, Emilia M.; Mukherjee, Chirantani; van de Kamp, Gerarda; Roobol, Stefan J.; Rother, Magdalena B.; van der Gulden, Hanneke; de Bruijn, Roebi; Lattanzio, Maria Valeria; van der Burg, Eline; Drenth, Anne Paulien; Verkaik, Nicole S.; Hahn, Kerstin; Klarenbeek, Sjoerd; De Korte-Grimmerink, Renske; van de Ven, Marieke; Pritchard, Colin E. J.; Huijbers, Ivo J.; Xia, Bing; van Gent, Dik C.; Essers, Jeroen; van Attikum, Haico; Chaudhuri, Arnab Ray; Bouwman, Peter; Jonkers, Jos
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages

人诱导多能干细胞中内源性血红素oxygenase-1的荧光标记，用于各种分化谱系中氧化应激的高含量成像

ARCHIVES OF TOXICOLOGY
IF6.9
2021-09-0416
OAAI
Snijders, Kirsten E.; Feher, Anita; Tancos, Zsuzsanna; Bock, Istvan; Teglasi, Annamaria; van den Berk, Linda; Niemeijer, Marije; Bouwman, Peter; Le Devedec, Sylvia E.; Mone, Martijn J.; Van Rossom, Rob; Kumar, Manoj; Wilmes, Anja; Jennings, Paul; Verfaillie, Catherine M.; Kobolak, Julianna; ter Braak, Bas; Dinnyes, Andras; van de Water, Bob
Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury
BIOCHEMICAL PHARMACOLOGY
IF5.6
2021-08-0115
OAAI
Wijaya, Lukas Surya; Trairatphisan, Panuwat; Gabor, Attila; Niemeijer, Marije; Keet, Jason; Morera, Ariadna Alcala; Snijders, Kirsten E.; Wink, Steven; Yang, Huan; Schildknecht, Stefan; Stevens, James L.; Bouwman, Peter; Kamp, Hennicke; Hengstler, Jan; Beltman, Joost; Leist, Marcel; Le Devedec, Sylvia; Saez-Rodriguez, Julio; van de Water, Bob
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
CELL REPORTS
IF6.9
2020-08-0129
OAAI
Francica, Paola; Mutlu, Merve; Blomen, Vincent A.; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M.; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L.; Lingg, Lea; Klebic, Ismar; van de Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A.; Fendler, Wojciech; Chapman, J. Ross; Brummelkamp, Thijn; Rottenberg, Sven
Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation

遗传性乳腺癌和卵巢癌基因中临床意义不确定的变异: 临床注释功能分析的最佳实践

JOURNAL OF MEDICAL GENETICS
IF3.7
2020-03-0934
OAAI
Monteiro, Alvaro N.; Bouwman, Peter; Kousholt, Arne N.; Eccles, Diana M.; Millot, Gael A.; Masson, Jean-Yves; Schmidt, Marjanka K.; Sharan, Shyam K.; Scully, Ralph; Wiesmueller, Lisa; Couch, Fergus; Vreeswijk, Maaike P. G.
EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
CLINICAL CANCER RESEARCH
IF10.2
2019-07-1538
OAAI
Puppe, Julian; Opdam, Mark; Schouten, Philip C.; Jozwiak, Katarzyna; Lips, Esther; Severson, Tesa; van de Ven, Marieke; Brambillasca, Chiara; Bouwman, Peter; van Tellingen, Olaf; Bernards, Rene; Wesseling, Jelle; Eichler, Christian; Thangarajah, Fabinshy; Malter, Wolfram; Pandey, Gaurav Kumar; Ozretic, Luka; Caldas, Carlos; van Lohuizen, Maarten; Hauptmann, Michael; Rhiem, Kerstin; Hahnen, Eric; Reinhardt, H. Christian; Buettner, Reinhard; Mallmann, Peter; Schoemig-Markiefka, Birgid; Schmutzler, Rita; Linn, Sabine; Jonkers, Jos
PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer

PARP抑制剂的疗效取决于三阴性乳腺癌BRCA缺陷模型中通过肿瘤内STING途径激活的CD8 T细胞募集

CANCER DISCOVERY
IF33.3
2019-06-03471
OAAI
Pantelidou, Constantia; Sonzogni, Olmo; Taveira, Mateus De Oliveria; Mehta, Anita K.; Kothari, Aditi; Wang, Dan; Visal, Tanvi; Li, Michelle K.; Pinto, Jocelin; Castrillon, Jessica A.; Cheney, Emily M.; Bouwman, Peter; Jonkers, Jos; Rottenberg, Sven; Guerriero, Jennifer L.; Wulf, Gerburg M.; Shapiro, Geoffrey, I

研究方向

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J
Jos Jonkers
H 指数:0论文数:5被引数:8
J
Jos Jonkers
H 指数:109论文数:920被引数:5.4万
H
Hanneke van der Gulden
H 指数:15论文数:85被引数:5,108
S
Sven Rottenberg
H 指数:48论文数:298被引数:1.4万
M
Marieke van de Ven
H 指数:32论文数:253被引数:7,371
M
Madalena Tarsounas
H 指数:40论文数:79被引数:8,743
B
Bob van de Water
H 指数:61论文数:436被引数:1.2万
E
Eline van der Burg
H 指数:21论文数:146被引数:3,010
S
Sjoerd Klarenbeek
H 指数:22论文数:167被引数:1,944
M
Mark Pieterse
H 指数:11论文数:76被引数:2,633