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R

Raphaël Gottardo

centre hospitalier universitaire vaudois

68H指数
483论文数
4.2W被引数
收录论文 116
发表时间
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Reprogramming engineered autologous T cells to overcome resistance in patients with Merkel cell carcinoma将工程化自体T细胞重编程以克服 Merkel细胞癌患者的耐药性
errScience Translational Medicine
IF14.6
err2026-09-09
err0
PREAI
errYuta Asano; Joshua R. Veatch; Cheng-Jung Sung; Tzu-Hao Tang; Francesco Mazziotta; Seiji Natsuki; Megan McAfee; Jakob Bakhtiari; Bo Lee; Lauren Martin; Alessandro Rizzi; Tianzi Zhang; Colton W. Smith; Kelly G. Paulson; Thomas M. Schmitt; Evan W. Newell; Anna E. Elz; Daniel G. Chen; Yapeng Su; Heather H. Gustafson; Cecilia C. S. Yeung; Brandon Seaton; Daniel Hunter; David M. Koelle; Shailender Bhatia; Evan T. Hall; Valentin Voillet; Jianhong Cao; Ted Gooley; Philip D. Greenberg; Raphael Gottardo; Shannon K. Oda; Paul Nghiem; Aude G. Chapuis
err分享
err收藏
Beyond benchmarking: an expert-guided consensus approach to spatially aware clustering超越基准测试：一种专家引导的共识方法用于空间感知聚类
errNature Methods
IF32.1
err2026-08-24
err0
errOAAI
errJieran Sun; Kirti Biharie; Peiying Cai; Niklas Müller-Bötticher; Paul Kiessling; Meghan A. Turner; Søren Helweg Dam; Florian Heyl; Sarusan Kathirchelvan; Martin Emons; Samuel Gunz; Sven Twardziok; Amin El-Heliebi; Martin Zacharias; Roland Eils; Marcel Reinders; Raphael Gottardo; Christoph Kuppe; Brian Long; Ahmed Mahfouz; Mark D. Robinson; Naveed Ishaque
err分享
err收藏
Mapping immune responses to TAK-003 dengue vaccine: immunogenicity across the clinical development programTAK-003登革热疫苗的免疫反应图谱：临床开发计划中的免疫原性
errFrontiers in Immunology
IF5.9
err2026-07-23
err0
errOAAI
errSM Sanja Mandaric; TE Tarek El Hindi; EJ Eduardo J. M. Nascimento; XS Xavier Saez-Llorens; CB Charissa Borja-Tabora; HF Heather Friberg; VT Vianney Tricou; NR Nicholas Roubinis; RG Raphael Gottardo; JR Jeffrey R. Currier; MS Mayuri Sharma; SB Shibadas Biswal
err分享
err收藏
Resolving sensitivity, specificity and signal contamination in Xenium spatial transcriptomics解析Xenium空间转录组学中的敏感性、特异性和信号污染
errNature Methods
IF32.1
err2026-04-30
err0
errOAAI
errMariia Bilous; Daria Buszta; Jonathan Bac; Senbai Kang; Yixing Dong; Stephanie Tissot; Sylvie Andre; Marina Alexandre Gaveta; Christel Voize; Solange Peters; Krisztian Homicsko; Raphael Gottardo
err分享
err收藏
Multiplexed single-cell and spatial profiling reveal B cells and tertiary lymphoid structures as prognostic indicators in pleural mesothelioma多重单细胞和空间分析揭示B细胞和三级淋巴结构作为胸膜间皮瘤的预后指标
errBritish Journal of Cancer
IF6.8
err2026-04-27
err0
errOAAI
errAngelica Rigutto; Nicolás G. Núñez; Jenny C. Kienzler; Isabelle Opitz; Mayura Meerang; Martina Haberecker; Nadine Fournier; Joao Lourenço; Raphael Gottardo; Karina Silina; Anurag Gupta; Burkhard Becher; Alessandra Curioni-Fontecedro
err分享
err收藏
Humoral and cellular responses to a tetravalent dengue vaccine (TAK-003) in adults from a dengue non-endemic region: An open-label phase 2 trial对来自非登革热流行区的成人接种四价登革热疫苗（TAK-003）后的体液和细胞免疫反应：一项开放标签二期临床试验
errVaccine
IF3.5
err2026-04-02
err0
errOAAI
errMandaric, Sanja; Friberg, Heather; Gottardo, Raphael; Messer, William; Tricou, Vianney; Faccin, Alice; Roubinis, Nicholas; Nadeem, Iqra; Gray, Lauren; Sharma, Mayuri; Currier, Jeffrey R.; Biswal, Shibadas
err分享
err收藏
The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction泛素连接酶KLHL6驱动CD8+ T细胞功能失调的耐药性
errNature
IF48.5
err2026-01-14
err0
errOAAI
errHongcheng Cheng; Yapeng Su; Xiaoli Pan; Yue Xu; Ermei Xie; Jing Du; Daniel G. Chen; Xiaomeng Dai; Raphael Gottardo; Philip D. Greenberg; Guideng Li
err分享
err收藏
Triple checkpoint blockade, but not anti-PD-1 alone, enhances engineered adoptive T cell therapy in a mouse model of advanced ovarian cancer
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errAnderson, Kristin G.; Alencar, Gabriel; Burnett, Madison G.; Nelson, Anders; Su, Yapeng; Voillet, Valentin; Bates, Breanna M.; Rodgers Suarez, Magdalia L.; Ruskin, Susan L.; Bekiranov, Stefan; Gottardo, Raphael; Greenberg, Philip D.
err分享
err收藏
Bcl6 expression is associated with a distinct immune landscape and spatial transcriptome in COVID-19
errJCI INSIGHT
IF6.1
err2025-10-22
err0
errOAAI
errBrenna, Cloe; Mora, Bernat Bramon; Ioannidou, Kalliopi; Bodelet, Julien; Siebmanns, Mia L.; Burgermeister, Simon; Georgakis, Spiros; Orfanakis, Michail; Muller, Yannick D.; Sedille, Nazanin; Feinstein, Matthew J.; Lomasney, Jon W.; Chen, Oliver Y.; Pantaleo, Giuseppe; Berezowska, Sabina; de Leval, Laurence; Gottardo, Raphael; Petrovas, Constantinos
err分享
err收藏
Cellular and molecular determinants mediating the dysregulated germinal center immune dynamics in systemic lupus erythematosus
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-02-13
err0
errOAAI
errGeorgakis, Spiros; Ioannidou, Kalliopi; Mora, Bernat Bramon; Orfanakis, Michail; Brenna, Cloe; Mueller, Yannick D.; Estrada, Perla M. Del Rio; Sharma, Ashish A.; Pantaleo, Giuseppe; de Leval, Laurence; Comte, Denis; Gottardo, Raphael; Petrovas, Constantinos
err分享
err收藏
tagtango: an application to compare single-cell annotationstagtango: 一个用于比较单细胞注释的应用程序
errBIOINFORMATICS
IF5.4
err2025-01-11
err0
errOAAI
errMora, Bernat Bramon; Lindsay, Helen; Thiebaut, Antonin; Stuart, Kenneth D.; Gottardo, Raphael
err分享
err收藏
Immune modules to guide diagnosis and personalized treatment of inflammatory skin diseases
errNATURE COMMUNICATIONS
IF15.7
err2024-12-18
err0
errOAAI
errSeremet, Teofila; Di Domizio, Jeremy; Girardin, Antoine; Yatim, Ahmad; Jenelten, Raphael; Messina, Francesco; Saidoune, Fanny; Schlapbach, Christoph; Bogiatzi, Sofia; Minisini, Frederic; Garzorz-Stark, Natalie; Leuenberger, Matthieu; Wuethrich, Heloise; Vernez, Maxime; Hohl, Daniel; Eyerich, Stefanie; Eyerich, Kilian; Guenova, Emmanuella; Paul, Carle; Gottardo, Raphael; Conrad, Curdin; Gilliet, Michel
err分享
err收藏
Long term T cell response and safety of a tetravalent dengue vaccine in healthy children
errNPJ VACCINES
IF6.5
err2024-10-17
err1
errOAAI
errMandaric, Sanja; Friberg, Heather; Saez-Llorens, Xavier; Borja-Tabora, Charissa; Biswal, Shibadas; Escudero, Ian; Faccin, Alice; Gottardo, Raphael; Brose, Manja; Roubinis, Nicholas; Fladager, Darlene; Deantonio, Rodrigo; Dimero, Julie Anne L.; Montenegro, Nathali; Folschweiller, Nicolas; Currier, Jeffrey R.; Sharma, Mayuri; Tricou, Vianney
err分享
err收藏
Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion组蛋白标记识别解析car-t起源子集，临床潜力和扩展的新型转录因子
errNATURE COMMUNICATIONS
IF15.7
err2024-09-27
err0
errOAAI
errFiorenza, S.; Zheng, Y.; Purushe, J.; Bock, T. J.; Sarthy, J.; Janssens, D. H.; Sheih, A. S.; Kimble, E. L.; Kirchmeier, D.; Phi, T. D.; Gauthier, J.; Hirayama, A. V.; Riddell, S. R.; Wu, Q.; Gottardo, R.; Maloney, D. G.; Yang, J. Y. H.; Henikoff, S.; Turtle, C. J.
err分享
err收藏
RAIN: machine learning-based identification for HIV-1 bNAbs
errNATURE COMMUNICATIONS
IF15.7
err2024-06-24
err1
errOAAI
errFoglierini, Mathilde; Nortier, Pauline; Schelling, Rachel; Winiger, Rahel R.; Jacquet, Philippe; O'Dell, Sijy; Demurtas, Davide; Mpina, Maxmillian; Lweno, Omar; Muller, Yannick D.; Petrovas, Constantinos; Daubenberger, Claudia; Perreau, Matthieu; Doria-Rose, Nicole A.; Gottardo, Raphael; Perez, Laurent
err分享
err收藏
The tidyomics ecosystem: enhancing omic data analyses
errNATURE METHODS
IF32.1
err2024-06-14
err2
PREAI
errHutchison, William J.; Keyes, Timothy J.; Crowell, Helena L.; Serizay, Jacques; Soneson, Charlotte; Davis, Eric S.; Sato, Noriaki; Moses, Lambda; Tarlinton, Boyd; Nahid, Abdullah A.; Kosmac, Miha; Clayssen, Quentin; Yuan, Victor; Mu, Wancen; Park, Ji-Eun; Mamede, Izabela; Ryu, Min Hyung; Axisa, Pierre-Paul; Paiz, Paulina; Poon, Chi-Lam; Tang, Ming; Gottardo, Raphael; Morgan, Martin; Lee, Stuart; Lawrence, Michael; Hicks, Stephanie C.; Nolan, Garry P.; Davis, Kara L.; Papenfuss, Anthony T.; Love, Michael I.; Mangiola, Stefano
err分享
err收藏
Long-term Remissions Following CD20-Directed Chimeric Antigen Receptor-Adoptive T-cell Therapy
errBLOOD CANCER DISCOVERY
IF11.5
err2024-05-10
err0
PREAI
errMo, George; Lee, Sang Y.; Coffey, David G.; Voillet, Valentin; Kirsch, Ilan R.; Gottardo, Raphael; Smythe, Kimberly S.; Yeung, Cecilia C. S.; Greenbaum, Adam; Green, Damian J.; Maloney, David G.; Till, Brian G.
err分享
err收藏
Triple checkpoint blockade, but not anti-PD1 alone, enhances the efficacy of engineered adoptive T cell therapy in advanced ovarian cancer
errCANCER RESEARCH
IF16.6
err2024-03-04
err0
PREAI
errAnderson, Kristin G.; Su, Yapeng; Burnett, Madison G.; Bates, Breanna M.; Suarez, Magdalia L. Rodgers; Ruskin, Susan L.; Voillet, Valentin; Gottardo, Raphael; Greenberg, Philip D.
err分享
err收藏
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanoma对肿瘤浸润淋巴细胞过继治疗的反应与黑色素瘤中预先存在的CD8 T髓样细胞网络有关
errSCIENCE IMMUNOLOGY
IF16.3
err2024-02-02
err16
errOAAI
errBarras, David; Ghisoni, Eleonora; Chiffelle, Johanna; Orcurto, Angela; Dagher, Julien; Fahr, Noemie; Benedetti, Fabrizio; Crespo, Isaac; Grimm, Alizee J.; Morotti, Matteo; Zimmermann, Stefan; Duran, Rafael; Imbimbo, Martina; de Olza, Maria Ochoa; Navarro, Blanca; Homicsko, Krisztian; Bobisse, Sara; Labes, Danny; Tsourti, Zoe; Andriakopoulou, Charitini; Herrera, Fernanda; Petremand, Remy; Dummer, Reinhard; Berthod, Gregoire; Kraemer, Anne I.; Huber, Florian; Thevenet, Jonathan; Bassani-Sternberg, Michal; Schaefer, Niklaus; Prior, John O.; Matter, Maurice; Aedo, Veronica; Dromain, Clarisse; Corria-Osorio, Jesus; Tissot, Stephanie; Kandalaft, Lana E.; Gottardo, Raphael; Pittet, Mikael; Sempoux, Christine; Michielin, Olivier; Dafni, Urania; Trueb, Lionel; Harari, Alexandre; Laniti, Denarda Dangaj; Coukos, George
err分享
err收藏
An approach for integrating multimodal omics data into sparse and interpretable models
errCELL REPORTS METHODS
IF4.5
err2024-02-01
err0
errOAAI
errDong, Yixing; Gottardo, Raphael
err分享
err收藏

研究方向

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