David Gate - Publications, H-index & Citations

David Gate

Northwestern University

31H指数

96论文数

7.1K被引数

收录论文 29

发表时间

Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming ALS中整合的单细胞和空间转录组分析揭示了外周到中枢的免疫浸润和重编程

Nature Neuroscience

IF20

2026-05-14

OAAI

Ziyang Zhang; Lynn van Olst; Francesco Alessandrini; Matthew Wright; Alex J. Edwards; Jake Boles; Anait Nalbandian; Anne V. Forsyth; Nate Shepard; Thomas Watson; Evan Kaspi; Angeli Mittal; Joshua Kuruvilla; Natalie Piehl; Abhirami Ramakrishnan; Stanley Appel; Evangelos Kiskinis; David Gate

Mosaic integration of spatial multi-omics with SpaMosaic 基于SpaMosaic的空间多组学镶嵌整合

Nature Genetics

IF29

2026-04-24

PREAI

Xuhua Yan; Zhaoyu Fang; Kok Siong Ang; Lynn van Olst; Alex Edwards; Thomas Watson; Ruiqing Zheng; Di Zhang; Rong Fan; Min Li; David Gate; Jinmiao Chen

Astrocytes engineered to fight Alzheimer’s plaques 设计用于对抗阿尔茨海默氏症斑块的星形胶质细胞

Science

IF45.8

2026-03-05

PREAI

Jake Boles; David Gate

The Sixth Annual Symposium of the Midwest Aging Consortium

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

IF0

2025-12-22

OAAI

Ines Sturmlechner; Sarah A Ashiqueali; Hélène Martini; Karla Valdivieso; Ana Catarina Franco; Prashanth Guthikonda; Andrew J Dosch; Luis I Prieto; Niels C Asmussen; Amanda S Latham; James T Redden; Ethan A Leitschuh; Douglas G Mashek; João F Passos; Jhonny Rodriguez-Lopez; T Blake Monroe; David A Bernlohr; Paul D Robbins; Bailey A Knopf; Dudley W Lamming; Matthew J Johnston; Holly M Brown-Borg; Spencer A Tye; Timothy W Rhoads; David M Gate; Bennett G Childs; Darren J Baker; Xinna Li; In Hwa Jang; Christina D Camell; Zachary Miller; Hemali Phatnani; Adam R Konopka; Andrew J Haak; Natalia Vanegas-Avendano; Ramya N Akula; Ajinkya R Limkar; William A Ricke; Scott F Leiser; Jacinta Correia; Hua Bai; Szczepan Olszewski; Kenneth L Seldeen; G R Scott Budinger; Luisa C Morales-Nebreda; Deborah R Winter; Shelly K Mccrady-Spitzer; Rozalyn M Anderson; Maria M Mihaylova; Mauricio Rojas; Ana L Mora; Nathan K Lebrasseur; Marissa J Schafer

Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging

NEUROBIOLOGY OF DISEASE

IF5.6

2024-11-01

OAAI

Jeon, Sohee; Salvo, Miranda A.; Alia, Alia O.; Popovic, Jelena; Zagardo, Mitchell; Chandra, Sidhanth; Nassan, Malik; Gate, David; Vassar, Robert; Cuddy, Leah K.

Anti-CD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8+ T-cell cytotoxicity after traumatic brain injury

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-10-19

OAAI

Chen, Zhangying; Ford, Kacie P.; Islam, Mecca B. A. R.; Wan, Hanxiao; Han, Hyebin; Ramakrishnan, Abhirami; Brown, Ryan J.; Villanueva, Veronica; Wang, Yidan; Davis, Booker T.; Weiss, Craig; Cui, Weiguo; Gate, David; Schwulst, Steven J.

Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference APOE和痴呆症研究的进展: 2023 AAIC进展的亮点: APOE会议

ALZHEIMERS & DEMENTIA

IF11.1

2024-07-19

OAAI

Kloske, Courtney M.; Belloy, Michael E.; Blue, Elizabeth E.; Bowman, Gregory R.; Carrillo, Maria C.; Chen, Xiaoying; Chiba-Falek, Ornit; Davis, Albert A.; Di Paolo, Gilbert; Garretti, Francesca; Gate, David; Golden, Lesley R.; Heinecke, Jay W.; Herz, Joachim; Huang, Yadong; Iadecola, Costantino; Johnson, Lance A.; Kanekiyo, Takahisa; Karch, Celeste M.; Khvorova, Anastasia; Koppes-den Hertog, Sascha J.; Lamb, Bruce T.; Lawler, Paige E.; Guen, Yann Le; Litvinchuk, Alexandra; Liu, Chia-Chen; Mahinrad, Simin; Marcora, Edoardo; Marino, Claudia; Michaelson, Danny M.; Miller, Justin J.; Morganti, Josh M.; Narayan, Priyanka S.; Naslavsky, Michel S.; Oosthoek, Marlies; Ramachandran, Kapil V.; Ramakrishnan, Abhirami; Raulin, Ana-Caroline; Robert, Aiko; Saleh, Rasha N. M.; Sexton, Claire; Shah, Nilomi; Shue, Francis; Sible, Isabel J.; Soranno, Andrea; Strickland, Michael R.; Julia, T. C. W.; Thierry, Manon; Tsai, Li-Huei; Tuckey, Ryan A.; Ulrich, Jason D.; van der Kant, Rik; Wang, Na; Wellington, Cheryl L.; Weninger, Stacie C.; Yassine, Hussein N.; Zhao, Na; Bu, Guojun; Goate, Alison M.; Holtzman, David M.

Deciphering spatial domains from spatial multi-omics with SpatialGlue 用空间胶水从空间多组学中破译空间域

NATURE METHODS

IF32.1

2024-06-21

OAAI

Long, Yahui; Ang, Kok Siong; Sethi, Raman; Liao, Sha; Heng, Yang; van Olst, Lynn; Ye, Shuchen; Zhong, Chengwei; Xu, Hang; Zhang, Di; Kwok, Immanuel; Husna, Nazihah; Jian, Min; Ng, Lai Guan; Chen, Ao; Gascoigne, Nicholas R. J.; Gate, David; Fan, Rong; Xu, Xun; Chen, Jinmiao

Epigenetic dysregulation in Alzheimer's disease peripheral immunity

NEURON

IF15

2024-04-01

PREAI

Ramakrishnan, Abhirami; Piehl, Natalie; Simonton, Brooke; Parikh, Milan; Zhang, Ziyang; Teregulova, Victoria; van Olst, Lynn; Gate, David

Transcriptomic Pr; iling Identifies CD8+ T Cells in the Brain; Aged and Alzheimer?s Disease Transgenic Mice as Tissue-Resident Memory T Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2022-10-01

OAAI

Altendorfer, Barbara; Unger, Michael Stefan; Poupardin, Rodolphe; Hoog, Anna; Asslaber, Daniela; Gratz, Iris Karina; Mrowetz, Heike; Benedetti, Ariane; Bessa de Sousa, Diana Marisa; Greil, Richard; Egle, Alexander; Gate, David; Wyss-Coray, Tony; Aigner, Ludwig

New Perspectives on Immune Involvement in Parkinson's Disease Pathogenesis

JOURNAL OF PARKINSONS DISEASE

IF5

2022-09-27

OAAI

Gate, David

Infection and inflammation: New perspectives on Alzheimer's disease 感染和炎症: 阿尔茨海默病的新观点

brain behavior and immunity

IF3.5

2022-07-01

OAAI

Whitson, Heather E.; Colton, Carol; El Khoury, Joseph; Gate, David; Goate, Alison; Heneka, Michael T.; Kaddurah-Daouk, Rima; Klein, Robyn S.; Shinohara, Mari L.; Sisodia, Sangram; Spudich, Serena S.; Stevens, Beth; Tanzi, Rudolph; Ting, Jenny P.; Garden, Gwenn

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-12-01

OAAI

Pluvinage, John, V; Sun, Jerry; Claes, Christel; Flynn, Ryan A.; Haney, Michael S.; Iram, Tal; Meng, Xiangling; Lindemann, Rachel; Riley, Nicholas M.; Danhash, Emma; Chadarevian, Jean Paul; Tapp, Emma; Gate, David; Kondapavulur, Sravani; Cobos, Inma; Chetty, Sundari; Pasca, Anca M.; Pasca, Sergiu P.; Berry-Kravis, Elizabeth; Bertozzi, Carolyn R.; Blurton-Jones, Mathew; Wyss-Coray, Tony

Neuroinflammation in Alzheimer's disease

JOURNAL OF THE NEUROLOGICAL SCIENCES

IF3.2

2021-10-01

PREAI

Gate, David

Methods to investigate intrathecal adaptive immunity in neurodegeneration

MOLECULAR NEURODEGENERATION

IF17.5

2021-01-22

OAAI

Oh, Hamilton; Leventhal, Olivia; Channappa, Divya; Henderson, Victor W.; Wyss-Coray, Tony; Lehallier, Benoit; Gate, David

Undulating changes in human plasma proteome profiles across the lifespan 人血浆蛋白质组在整个生命周期中的波动变化

NATURE MEDICINE

IF50

2019-12-05

482

OAAI

Lehallier, Benoit; Gate, David; Schaum, Nicholas; Nanasi, Tibor; Lee, Song Eun; Yousef, Hanadie; Losada, Patricia Moran; Berdnik, Daniela; Keller, Andreas; Verghese, Joe; Sathyan, Sanish; Franceschi, Claudio; Milman, Sofiya; Barzilai, Nir; Wyss-Coray, Tony

Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-05-18

OAAI

Yang, Andrew C.; Du Bois, Haley; Olsson, Niclas; Gate, David; Lehallier, Benoit; Berdnik, Daniela; Brewer, Kyle D.; Bertozzi, Carolyn R.; Elias, Joshua E.; Wyss-Coray, Tony

Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance

JOURNAL OF VIROLOGY

IF3.8

2017-01-01

OAAI

Acharya, Dhiraj; Wang, Penghua; Paul, Amber M.; Dai, Jianfeng; Gate, David; Lowery, Jordan E.; Stokic, Dobrivoje S.; Leis, A. Arturo; Flavell, Richard A.; Town, Terrence; Fikrig, Erol; Bai, Fengwei

CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1

JOURNAL OF VIROLOGY

IF3.8

2016-05-15

OAAI

Mott, Kevin R.; Gate, David; Matundan, Harry H.; Ghiasi, Yasamin N.; Town, Terrence; Ghiasi, Homayon

Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection

PLOS PATHOGENS

IF4.9

2015-11-30

OAAI

Tseng, Ching Wen; Biancotti, Juan Carlos; Berg, Bethany L.; Gate, David; Kolar, Stacey L.; Mueller, Sabrina; Rodriguez, Maria D.; Rezai-Zadeh, Kavon; Fan, Xuemo; Beenhouwer, David O.; Town, Terrence; Liu, George Y.

研究方向