Jason L. Stein - Publications, H-index & Citations

Jason L. Stein

University of North Carolina at Chapel Hill

57H指数

256论文数

1.9W被引数

收录论文 79

发表时间

Massively parallel assessment of gene regulatory activity at human cortical-structure-associated variants 大规模平行评估与人类皮层结构相关变异的基因调控活性

Nature Neuroscience

IF20

2026-09-23

OAAI

Nana Matoba; Jessica C. McAfee; Oleh Krupa; Alvaro A. Beltran; Jessica L. Bell; Brandon D. Le; Jordan M. Valone; Hyunggyu Min; Gregory E. Crawford; Jesse R. Raab; Hyejung Won; Jason L. Stein

Parallelized bright-field and fluorescence imaging platform for organoids 并行明场和荧光成像平台用于类器官

Cell Reports Methods

IF4.5

2026-09-15

OAAI

Kanghyun Kim; Rubal Singla; Amey Chaware; Jieun Park; Ina Klockner; Josh Lerner; Kevin Li; Fanghong Shen; Clay Dugo; Paul Reamey; Aurélien Bègue; Mark Harfouche; Abhishek Mishra; Christopher A. McPherson; Jason L. Stein; Roarke Horstmeyer

A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex 单细胞多组学分析识别发育中唐氏综合征新皮层失调的分子和基因调控机制

Science

IF45.8

2026-04-23

PREAI

Celine K. Vuong; Alexis Weber; Patrick Seong; Nana Matoba; Yu-Jen Chen; Jordan Peyer; Shahab Younesi; Angelo Salinda; Daniel Gomez; Gabriella Rivas; Abril Morales; Beck Shafie; Pan Zhang; Susanne Nichterwitz; Le Qi; Nolan T. Fernandez; Emily Friedman; Michael I. Love; Michael J. Gandal; Daniel H. Geschwind; William E. Lowry; Jason L. Stein; Luis de la Torre-Ubieta

Assessing molecular gene by treatment interactions using a population of neural progenitors exposed to valproic acid and lithium 评估分子基因与治疗之间的相互作用，使用暴露于丙戊酸和锂的神经前体细胞群体

Molecular Psychiatry

IF10.1

2026-04-04

OAAI

Jordan M. Valone; Brandon D. Le; Nana Matoba; Jessica T. Mory; Justin M. Wolter; Michael I. Love; Jason L. Stein

Computation and resource efficient genome-wide association analysis for large-scale imaging studies 计算和资源高效的基因组范围关联分析，用于大规模成像研究

Nature Communications

IF15.7

2026-02-28

OAAI

Zhiwen Jiang; Jason Stein; Tengfei Li; Ethan Fang; Yun Li; Patrick Sullivan; Hongtu Zhu

Mapping rare protein-coding variants on multi-organ imaging traits 将罕见蛋白质编码变体映射到多器官成像性状上

Nature Communications

IF15.7

2025-12-23

OAAI

Yijun Fan; Jie Chen; Zirui Fan; Julio Chirinos; Jason L. Stein; Patrick F. Sullivan; Rujin Wang; Ajay Nadig; David Y. Zhang; Shuai Huang; Zhiwen Jiang; Peter Yi Guan; Xinjie Qian; Ting Li; Haoyue Li; Zehui Sun; Marylyn D. Ritchie; Joan M. O’Brien; Walter Witschey; Daniel J. Rader; Tengfei Li; Hongtu Zhu; Bingxin Zhao

TSC tunes progenitor balance and upper-layer neuron generation in neocortex TSC调控新皮层中的前体细胞平衡和上层神经元生成。

Nature

IF48.5

2025-12-03

PREAI

Cristine R. Casingal; Naoki Nakagawa; Keiko Yabuno-Nakagawa; Cailyn Meyer; Siling Liu; Vasiliki Gkini; Su-Ji Cho; Mario Skarica; Dan Liang; Jeremy M. Simon; Nana Matoba; Ahana Mallick; Rubal Singla; Jieun Park; Chu-Wei Huang; Hailey Wilson; Janice Lee; H. Troy Ghashghaei; Garret D. Stuber; Oskari Heikinheimo; Takashi Namba; Jason L. Stein; E. S. Anton

AAV-dCas9 vector unsilences paternal Ube3a in neurons by impeding Ube3a-ATS transcription AAV-dCas9载体通过阻碍Ube3a-ATS转录来激活父源Ube3a在神经元中的表达

Communications Biology

IF5.1

2025-09-02

OAAI

Justin M. Wolter; Lucas M. James; Samantha L. Boeshore; Hanqian Mao; Eric S. McCoy; Daniel F. Ryan; Giulia Fragola; Bonnie Taylor-Blake; Jason L. Stein; Mark J. Zylka

Transparency and ongoing communication with participants in brain organoid research: Consensus of an interdisciplinary working group 脑类器官研究中的透明度与持续参与者沟通：跨学科工作组的共识

Stem Cell Reports

IF5.1

2025-06-26

OAAI

Betty Cohn; Megan Doerr; Pamela Feliciano; Stephanie M. Fullerton; Saskia Hendriks; Soren Holm; Insoo Hyun; Karin Jongsma; Karen M. Meagher; M. Elizabeth Ross; Jason L. Stein; Sharon F. Terry; Katherine E. MacDuffie

Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution Jason L Stein and Alex A Pollen

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2025-06-01

PREAI

Stein, Jason L.; Pollen, Alex A.

Probabilistic classification of gene-by-treatment interactions on molecular count phenotypes

PLOS GENETICS

IF3.7

2025-04-01

OAAI

Harigaya, Yuriko; Matoba, Nana; Le, Brandon D.; Valone, Jordan M.; Stein, Jason L.; Love, Michael, I; Valdar, William

Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-09-01

OAAI

Aygun, Nil; Vuong, Celine; Krupa, Oleh; Mory, Jessica; Le, Brandon D.; Valone, Jordan M.; Liang, Dan; Shafie, Beck; Zhang, Pan; Salinda, Angelo; Wen, Cindy; Gandal, Michael J.; Love, Michael I.; de la Torre-Ubieta, Luis; Stein, Jason L.

Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture

STEM CELL REPORTS

IF5.1

2024-09-01

OAAI

Glass, Madison R.; Waxman, Elisa A.; Yamashita, Satoshi; Lafferty, Michael; Beltran, Alvaro A.; Farah, Tala; Patel, Niyanta K.; Singla, Rubal; Matoba, Nana; Ahmed, Sara; Srivastava, Mary; Drake, Emma; Davis, Liam T.; Yeturi, Meghana; Sun, Kexin; Love, Michael I.; Hashimoto-Torii, Kazue; French, Deborah L.; Stein, Jason L.

Eye-brain connections revealed by multimodal retinal and brain imaging genetics 多模态视网膜和脑成像遗传学揭示的眼-脑连接

NATURE COMMUNICATIONS

IF15.7

2024-07-18

OAAI

Zhao, Bingxin; Li, Yujue; Fan, Zirui; Wu, Zhenyi; Shu, Juan; Yang, Xiaochen; Yang, Yilin; Wang, Xifeng; Li, Bingxuan; Wang, Xiyao; Copana, Carlos; Yang, Yue; Lin, Jinjie; Li, Yun; Stein, Jason L.; O'Brien, Joan M.; Li, Tengfei; Zhu, Hongtu

Rigor and reproducibility in human brain organoid research: Where we are and where we need to go

STEM CELL REPORTS

IF5.1

2024-06-01

OAAI

Sandoval, Soraya O.; Cappuccio, Gerarda; Kruth, Karina; Osenberg, Sivan; Khalil, Saleh M.; Mendez-Albelo, Natasha M.; Padmanabhan, Krishnan; Wang, Daifeng; Niciu, Mark J.; Bhattacharyya, Anita; Stein, Jason L.; Sousa, Andre M. M.; Waxman, Elisa A.; Buttermore, Elizabeth D.; Whye, Dosh; Sirois, Carissa L.; Williams, Aislinn; Maletic-Savatic, Mirjana; Zhao, Xinyu

Mapping of neuronal and glial primary cilia contactome and connectome in the human cerebral cortex

NEURON

IF15

2024-01-01

PREAI

Wu, Jun Yao; Cho, Su-Ji; Descant, Katherine; Li, Peter H.; Shapson-Coe, Alexander; Januszewski, Michal; Berger, Daniel R.; Meyer, Cailyn; Casingal, Cristine; Huda, Ariba; Liu, Jiaqi; Ghashghaei, Tina; Brenman, Mikayla; Jiang, Michelle; Scarborough, Joseph; Pope, Art; Jain, Viren; Stein, Jason L.; Guo, Jiami; Yasuda, Ryohei; Lichtman, Jeff W.; Anton, E. S.

Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants 精神分裂症相关常见变异等位基因调节活性的系统研究

CELL GENOMICS

IF9

2023-10-01

OAAI

McAfee, Jessica C.; Lee, Sool; Lee, Jiseok; Bell, Jessica L.; Krupa, Oleh; Davis, Jessica; Insigne, Kimberly; Bond, Marielle L.; Zhao, Nanxiang; Boyle, Alan P.; Phanstiel, Douglas H.; Love, Michael I.; Stein, Jason L.; Ruzicka, W. Brad; Davila-Velderrain, Jose; Kosuri, Sriram; Won, Hyejung

Donor perspectives on informed consent and use of biospecimens for brain organoid research 关于知情同意和使用生物样本进行脑类器官研究的供体观点

STEM CELL REPORTS

IF5.1

2023-07-01

OAAI

MacDuffie, Katherine E.; Stein, Jason L.; Doherty, Dan; Jayadev, Suman; Girault, Jessica B.; Emmons, Katherine A.; Glass, Madison Rose; Dempsey, Jennifer C.; Marrus, Natasha; Botteron, Kelly N.; Dager, Stephen R.; Estes, Annette M.; Piven, Joseph; Wilfond, Benjamin S.

Inferring cell-type-specific causal gene regulatory networks during human neurogenesis

GENOME BIOLOGY

IF9.4

2023-05-30

OAAI

Aygun, Nil; Liang, Dan; Crouse, Wesley L.; Keele, Gregory R.; Love, Michael I.; Stein, Jason L.

MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size

ELIFE

IF0

2023-01-11

OAAI

Lafferty, Michael J.; Ayguen, Nil; Patel, Niyanta K.; Krupa, Oleh; Liang, Dan; Wolter, Justin M.; Geschwind, Daniel H.; de la Torre-ubieta, Luis; Stein, Jason L.; Gleeson, Joseph G.

研究方向