Christopher J.B. Nicol - Publications, H-index & Citations

Christopher J.B. Nicol

mcmaster university

35H指数

122论文数

4.8K被引数

收录论文 40

发表时间

Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models 谷胱甘肽偶联的金纳米颗粒通过抑制NF-κB、NLRP3炎症小体轴，缓解3D人神经干细胞模型中淀粉样蛋白-β诱导的神经炎症和tau蛋白病

Experimental Cell Research

IF3.5

2026-04-01

PREAI

Yang, Yu-Ping; Nicol, Christopher J. B.; Yen, Chiahui; Chiang, Ming-Chang

Alexidine is a TAZ-specific small-molecule inhibitor that suppresses breast cancer invasion and metastasis Alexidine是一种TAZ特异性小分子抑制剂，可抑制乳腺癌的侵袭和转移。

iScience

IF4.1

2025-11-21

OAAI

Anni Ge; Lishui Niu; Rachel Rubino; Kimberly Seaman; Xin Song; Yawei Hao; Kody Klupt; Natasha Iaboni; Zongchao Jia; Lidan You; Christopher J.B. Nicol; Haian Fu; Yuhong Du; Xiaolong Yang

Application of Foundation Models for Colorectal Cancer Tissue Classification in Mass Spectrometry Imaging 基于质谱成像技术的结直肠癌组织分类中基础模型的应用

Technologies 2025, Vol. 13, Page 434

IF3.6

2025-09-29

OAAI

Alon Gabriel; Amoon Jamzad; Mohammad Farahmand; Martin Kaufmann; Natasha Iaboni; David Hurlbut; Kevin Yi Mi Ren; Christopher J. B. Nicol; John F. Rudan; Sonal Varma; Gabor Fichtinger; Parvin Mousavi

Evaluating rapid evaporative ionization mass spectrometry profiles of human breast cancer cells using a 3D in vitro assay 评估人乳腺癌细胞快速蒸发电离质谱谱图，使用3D体外测定法

Analytical and Bioanalytical Chemistry

IF3.8

2025-08-18

PREAI

Rachel E. Rubino; Martin Kaufmann; Amoon Jamzad; Natasha Iaboni; Kevin Yi Mi Ren; Jian Yu; Haidy Metwally; Manuela Kunz; John F. Rudan; Parvin Mousavi; Gabor Fichtinger; Richard Oleschuk; Christopher J. B. Nicol

A Review of the Neuroprotective Properties of Exosomes Derived from Stem Cells and Exosome-Coated Nanoparticles for Treating Neurodegenerative Diseases and Stroke 干细胞来源的外泌体及外泌体包被的纳米颗粒在治疗神经退行性疾病和中风中的神经保护特性综述

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-04-21

OAAI

Yang, Yu-Ping; Nicol, Christopher J. B.; Chiang, Ming-Chang

The α-MG exhibits neuroprotective potential by reducing amyloid beta peptide-induced inflammation, oxidative stress, and tau aggregation in human neural stem cells α-MG通过减少人神经干细胞中由β-淀粉样肽诱导的炎症、氧化应激和tau蛋白聚集，展现出神经保护潜力。

BRAIN RESEARCH

IF2.6

2025-04-01

PREAI

Chiang, Ming-Chang; Nicol, Christopher J. B.; Yang, Yu-Ping; Chiang, Tairui; Yen, Chiahui

Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP plus -Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammasome in SH-SY5Y Cells 白藜芦醇增强的人类神经干细胞来源的外泌体通过激活AMPK和Nrf2途径以及抑制SH-SY5Y细胞中NLRP3炎症小体来减轻MPP plus诱导的神经毒性

LIFE-BASEL

IF3.4

2025-02-13

OAAI

Chiang, Ming-Chang; Yang, Yu-Ping; Nicol, Christopher J. B.; Chiang, Tairui; Yen, Chiahui

A Novel Bioluminescent Biosensor Quantifying Intramolecular Interaction and Levels of Pyroptosis Effector GSDMD 一种新型生物发光生物传感器，可量化分子内相互作用和焦垂效应GSDMD的水平

CELLS

IF5.2

2024-09-25

OAAI

Kelly, Tynan; Bhandari, Simran; Carew, Madeleine; Rubino, Rachel; Nicol, Christopher; Yang, Xiaolong

Metabolically Active Zones Involving Fatty Acid Elongation Delineated by DESI-MSI Correlate with Pathological and Prognostic Features of Colorectal Cancer

METABOLITES

IF3.7

2023-03-31

OAAI

Kaufmann, Martin; Iaboni, Natasha; Jamzad, Amoon; Hurlbut, David; Ren, Kevin Yi Mi; Rudan, John F.; Mousavi, Parvin; Fichtinger, Gabor; Varma, Sonal; Caycedo-Marulanda, Antonio; Nicol, Christopher J. B.

GSH-AuNP anti-oxidative stress, ER stress and mitochondrial dysfunction in amyloid-beta peptide-treated human neural stem cells

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2022-07-01

PREAI

Chiang, Ming-Chang; Nicol, Christopher J. B.

TO901317 activation of LXR-dependent pathways mitigate amyloid-beta peptide-induced neurotoxicity in 3D human neural stem cell culture scaffolds and AD mice

BRAIN RESEARCH BULLETIN

IF3.7

2022-01-01

PREAI

Chiang, Ming-Chang; Nicol, Christopher J. B.; Chen, Shiang-Jiuun; Huang, Rong-Nan

Exposure to PM2.5 induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells

NEUROTOXICOLOGY

IF3.9

2022-01-01

PREAI

Lin, Chien-Hung; Nicol, Christopher J. B.; Wan, Chuan; Chen, Shiang-Jiuun; Huang, Rong-Nan; Chiang, Ming-Chang

A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells

SCIENTIFIC REPORTS

IF3.9

2021-05-17

OAAI

Yang, Xiaojing; Nanayakkara, Jina; Claypool, Duncan; Saghafinia, Sadegh; Wong, Justin J. M.; Xu, Minqi; Wang, Xiantao; Nicol, Christopher J. B.; Michael, Iacovos P.; Hafner, Markus; Yang, Xiaolong; Renwick, Neil

Nanogold induces anti-inflammation against oxidative stress induced in human neural stem cells exposed to amyloid-beta peptide

NEUROCHEMISTRY INTERNATIONAL

IF4

2021-05-01

PREAI

Chiang, Ming-Chang; Nicol, Christopher J. B.; Lin, Chien-Hung; Chen, Shiang-Jiuun; Yen, Chiahui; Huang, Rong-Nan

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection (vol 15, e1007597, 2019)

PLOS PATHOGENS

IF4.9

2020-11-04

OAAI

Evans, Robert J.; Pline, Katherine; Loynes, Catherine A.; Needs, Sarah; Aldrovandi, Maceler; Tiefenbach, Jens; Bielska, Ewa; Rubino, Rachel E.; Nicol, Christopher J.; May, Robin C.; Krause, Henry M.; O'Donnell, Valerie B.; Renshaw, Stephen A.; Johnston, Simon A.

An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications

FASEB JOURNAL

IF4.2

2020-02-18

PREAI

Dasgupta, Asish; Chen, Kuang-Hueih; Wu, Danchen; Hoskin, Victoria; Mewburn, Jeffrey; Lima, Patricia D. A.; Parlow, Leah R. G.; Hindmarch, Charles C. T.; Martin, Ashley; Sykes, Edward A.; Tayade, Chandrakant; Lightbody, Elizabeth D.; Madarnas, Yolanda; SenGupta, Sandip K.; Elliott, Bruce E.; Nicol, Christopher J. B.; Archer, Stephen L.

Phosphodiesterase 3B (PDE3B) antagonizes the anti-angiogenic actions of PKA in human and murine endothelial cells

CELLULAR SIGNALLING

IF3.7

2019-10-01

PREAI

MacKeil, Jodi L.; Brzezinska, Paulina; Burke-Kleinman, Jonah; Theilmann, Anne L.; Nicol, Christopher J. B.; Ormiston, Mark L.; Maurice, Donald H.

A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion

FASEB JOURNAL

IF4.2

2019-08-20

OAAI

Nouri, Kazem; Azad, Taha; Lightbody, Elizabeth; Khanal, Prem; Nicol, Christopher J.; Yang, Xiaolong

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection

PLOS PATHOGENS

IF4.9

2019-03-28

OAAI

Endothelial Cell-Targeted Deletion of PPARγ Blocks Rosiglitazone-Induced Plasma Volume Expansion and Vascular Remodeling in Adipose Tissue

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-03-01

OAAI

Akiyama, Taro E.; Skelhorne-Gross, Graham E.; Lightbody, Elizabeth D.; Rubino, Rachel E.; Shi, Jia Yue; McNamara, Lesley A.; Sharma, Neelam; Zycband, Emanuel, I; Gonzalez, Frank J.; Liu, Haiying; Woods, John W.; Chang, C. H.; Berger, Joel P.; Nicol, Christopher J. B.

研究方向