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收藏Immunotherapy with pVAX14 Nucleic Acid in Combination with All-Trans Retinoic Acid (ATRA) in an Acute Promyelocytic Leukemia (APL) Mouse Model Activates Cytotoxic T-Cells and Enhances Immune Responses: A Strategy for Turning Cold Tumors HotpVAX14核酸免疫疗法联合全反式维甲酸（ATRA）在急性早幼粒细胞白血病（APL）小鼠模型中激活细胞毒性T细胞并增强免疫应答：一种将冷肿瘤转变为热肿瘤的策略
Padua, Rose Ann; Patel, Satyananda; Smith, James; Omidvar, Dr; Tekin, Nilgun; Guidez, Fabien; Chiquet, Mathieu; Setterblad, Niclas; Mills, Ken, I; Pla, Marika; Krief, Patricia; Huet, Thierry; Chomienne, Christine; Fenaux, Pierre 分享 收藏 分享 收藏 The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1前神经基因ASCL1通过直接抑制间充质基因NDRG1来控制胶质母细胞瘤干细胞中的转录亚组隶属关系Narayanan, Ashwin; Gagliardi, Filippo; Gallotti, Alberto L.; Mazzoleni, Stefania; Cominelli, Manuela; Fagnocchi, Luca; Pala, Mauro; Piras, Ignazio S.; Zordan, Paola; Moretta, Nicole; Tratta, Elisa; Brugnara, Gianluca; Altabella, Luisa; Bozzuto, Giuseppina; Gorombei, Petra; Molinari, Agnese; Padua, Rose-Ann; Bulfone, Alessandro; Politi, Letterio S.; Falini, Andrea; Castellano, Antonella; Mortini, Pietro; Zippo, Alessio; Poliani, Pietro L.; Galli, Rossella 分享 收藏 Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-GenesisAbu Alex, Ansu; Ganesan, Saravanan; Palani, Hamenth Kumar; Balasundaram, Nithya; David, Sachin; Lakshmi, Kavitha M.; Kulkarni, Uday P.; Nisham, P. N.; Korula, Anu; Devasia, Anup J.; Janet, Nancy Beryl; Abraham, Aby; Srivastava, Alok; George, Biju; Padua, Rose Ann; Chomienne, Christine; Balasubramanian, Poonkuzhali; Mathews, Vikram 分享 收藏 Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemiaGanesan, S.; Alex, A. A.; Chendamarai, E.; Balasundaram, N.; Palani, H. K.; David, S.; Kulkarni, U.; Aiyaz, M.; Mugasimangalam, R.; Korula, A.; Abraham, A.; Srivastava, A.; Padua, R. A.; Chomienne, C.; George, B.; Balasubramanian, P.; Mathews, V. 分享 收藏 GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathwaysGuerenne, Laura; Beurlet, Stephanie; Said, Mohamed; Gorombei, Petra; Le Pogam, Carole; Guidez, Fabien; de la Grange, Pierre; Omidvar, Nader; Vanneaux, Valerie; Mills, Ken; Mufti, Ghulam J.; Sarda-Mantel, Laure; Noguera, Maria Elena; Pla, Marika; Fenaux, Pierre; Padua, Rose Ann; Chomienne, Christine; Krief, Patricia 分享 收藏 pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all-trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia micePatel, S.; Guerenne, L.; Gorombei, P.; Omidvar, N.; Schlageter, M-H; Alex, A. A.; Ganesan, S.; West, R.; Ades, L.; Mathews, V.; Krief, P.; Pla, M.; Fenaux, P.; Chomienne, C.; Padua, R. A. 分享 收藏 Lithium chloride antileukemic activity in acute promyelocytic leukemia is GSK-3 and MEK/ERK dependentZassadowski, F.; Pokorna, K.; Ferre, N.; Guidez, F.; Llopis, L.; Chourbagi, O.; Chopin, M.; Poupon, J.; Fenaux, P.; Padua, R. Ann; Pla, M.; Chomienne, C.; Cassinat, B. 分享 收藏 Prospective International Cohort Study Demonstrates Inability of Interim PET to Predict Treatment Failure in Diffuse Large B-Cell LymphomaCarr, Robert; Fanti, Stefano; Paez, Diana; Cerci, Juliano; Gyoerke, Tamas; Redondo, Francisca; Morris, Tim P.; Meneghetti, Claudio; Auewarakul, Chirayu; Nair, Reena; Gorospe, Charity; Chung, June-Key; Kuzu, Isinsu; Celli, Monica; Gujral, Sumeet; Padua, Rose Ann; Dondi, Maurizio 分享 收藏 分享 收藏 分享 收藏 Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimensFan, Alice C.; Deb-Basu, Debabrita; Orban, Mathias W.; Gotlib, Jason R.; Natkunam, Yasodha; O'Neill, Roger; Padua, Rose-Ann; Xu, Liwen; Taketa, Daryl; Shirer, Amy E.; Beer, Shelly; Yee, Ada X.; Voehringer, David W.; Felsher, Dean W. 分享 收藏 BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasiaOmidvar, Nader; Kogan, Scott; Beurlet, Stephanie; Pogam, Carole Ie; Janin, Anne; West, Robert; Noguera, Maria-Elena; Reboul, Murielle; Soulie, Annie; Leboeuf, Christophe; Setterblad, Niclas; Felsher, Dean; Lagasse, Eric; Mohamedali, Azim; Thomas, N. Shaun B.; Fenaux, Pierre; Fontenay, Michaela; Pla, Marika; Mufti, Ghulam J.; Weissman, Irving; Chomienne, Christine; Padua, Rose Ann 分享 收藏 Reactive oxygen species, DNA damage, and error-prone repair: A model for genomic instability with progression in myeloid leukemia?Rassool, Feyruz V.; Gaymes, Terry J.; Omidvar, Nader; Brady, Nicola; Beurlet, Stephanie; Pla, Marika; Reboul, Murielle; Lea, Nicholas; Chomienne, Christine; Thomas, Nicholas S. B.; Mufti, Ghulam J.; Padua, Rose Ann 分享 收藏 分享 收藏 分享 收藏 分享 收藏 PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemiaPadua, RA; Larghero, J; Robin, M; le Pogam, C; Schlageter, MH; Muszlak, S; Fric, J; West, R; Rousselot, P; Phan, TH; Mudde, L; Teisserenc, H; Carpentier, AF; Kogan, S; Degos, L; Pla, M; Bishop, JM; Stevenson, F; Charron, D; Chomienne, C 分享 收藏 分享 收藏 
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