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Effects of low salinities on the physiological and cellular response of the Ascidian Pyura chilensis: an experimental approach 低盐度对海鞘 Pyura chilensis 生理和细胞响应的影响：一种实验方法 Montory, Jaime A.; Perez-Valdes, Margarita; Colipan, Evelyn; Chaparro, Oscar R.; Cubillos, Victor M.; Lee, Matthew R.; Ramirez-Kuschel, Eduardo; Gebauer, Paulina; Salas-Yanquin, Luis P.; Buchner-Miranda, Joseline A. 分享 收藏
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Deep Turbulence as a Novel Main Driver for Multi-Specific Toxic Algal Blooms: The Case of an Anoxic and Heavy Metal-Polluted Submarine Canyon That Harbors Toxic Dinoflagellate Resting Cysts Rodriguez-Villegas, Camilo; Perez-Santos, Ivan; Diaz, Patricio A.; Baldrich, angela M.; Lee, Matthew R.; Saldias, Gonzalo S.; Mancilla-Gutierrez, Guido; Urrutia, Cynthia; Navarro, Claudio R.; Varela, Daniel A.; Ross, Lauren; Figueroa, Rosa I. 分享 收藏
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease Liu, Longbin; Malagu, Karine; Haughan, Alan F.; Khetarpal, Vinod; Stott, Andrew J.; Esmieu, William; Vater, Huw D.; Webster, Stephen J.; van de Poel, Amanda J.; Clissold, Cole; Cosgrove, Brett; Sutton, Benjamin; Spencer, Jonathan A.; Breccia, Perla; Gancia, Emanuela; Bonomo, Silvia; Ladduwahetty, Tammy; Lazari, Ovadia; Patel, Hiral; Atton, Helen C.; Clifton, Steve; Mota, Daniel M.; Magnani, Dario; O'Neill, Amy; Stebbeds, Marta; Macabuag, Natsuko; Todd, Daniel; Herva, Maria E.; Mitchell, Philip; Visser, Mijke; Compte Sancerni, Sara; Grand Moursel, Laure; da Silva, Marta; Kritikou, Eva; Heikkinen, Taneli T.; Bolkvadze, Tamuna; Fodale, Valentina; Spadafora, Debora; Daldin, Manuel; Bresciani, Alberto; Mangette, John E.; Doherty, Elizabeth M.; Lee, Matthew R.; Herbst, Todd; Monteagudo, Edith; Macdonald, Douglas; Plotnikov, Nikolay V.; Chambers, Mark; Mcallister, George; Munoz-Sanjuan, Ignacio; Dominguez, Celia 分享 收藏
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Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's Disease Ladduwahetty, Tammy; Lee, Matthew R.; Maillard, Michel C.; Cachope, Roger; Todd, Daniel; Barnes, Michael; Beaumont, Vahri; Chauhan, Alka; Gallati, Caroline; Haughan, Alan F.; Kempf, Georg; Luckhurst, Christopher A.; Matthews, Kim; McAllister, George; Mitchell, Philip; Patel, Hiral; Rose, Mark; Saville-Stones, Elizabeth; Steinbacher, Stefan; Stott, Andrew J.; Thatcher, Emma; Tierney, Jason; Urbonas, Liudvikas; Munoz-Sanjuan, Ignacio; Dominguez, Celia 分享 收藏
Drivers of dinoflagellate benthic cyst assemblages in the NW Patagonian Fjords System and its adjacent oceanic shelf, with a focus on harmful species Rodriguez-Villegas, Camilo; Lee, Matthew R.; Salgado, Pablo; Figueroa, Rosa, I; Baldrich, Angela; Perez-Santos, Ivan; Tomasetti, Stephen J.; Niklitschek, Edwin; Diaz, Manuel; Alvarez, Gonzalo; Marin, Sandra L.; Seguel, Miriam; Farias, Laura; Diaz, Patricio A. 分享 收藏
[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins Liu, Longbin; Johnson, Peter D.; Prime, Michael E.; Khetarpal, Vinod; Lee, Matthew R.; Brown, Christopher J.; Chen, Xuemei; Clark-Frew, Daniel; Coe, Samuel; Conlon, Mike; Davis, Randall; Ensor, Samantha; Esposito, Simone; Moren, Anton Forsberg; Gai, Xinjie; Green, Samantha; Greenaway, Catherine; Haber, James; Halldin, Christer; Hayes, Sarah; Herbst, Todd; Herrmann, Frank; He-mann, Manuela; Hsai, Ming Min; Kotey, Adrian; Mangette, John E.; Mills, Matthew R.; Monteagudo, Edith; Nag, Sangram; Nibbio, Martina; Orsatti, Laura; Schaertl, Sabine; Scheich, Christoph; Sproston, Joanne; Stepanov, Vladimir; Varnas, Katarina; Varrone, Andrea; Wityak, John; Mrzljak, Ladislav; Munoz-Sanjuan, Ignacio; Bard, Jonathan A.; Dominguez, Celia 分享 收藏
Discovery of Selective Small Molecule Degraders of BRAF-V600E Han, Xiao-Ran; Chen, Liqun; Wei, Yuanqi; Yu, Weihua; Chen, Yanke; Zhang, Chunyan; Jiao, Bingyang; Shi, Tingting; Sun, Lei; Zhang, Chao; Xu, Yang; Lee, Matthew R.; Luo, Ying; Plewe, Michael B.; Wang, Jialiang 分享 收藏
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Structural basis for GPR40 allosteric agonism and incretin stimulation Ho, Joseph D.; Chau, Betty; Rodgers, Logan; Lu, Frances; Wilbur, Kelly L.; Otto, Keith A.; Chen, Yanyun; Song, Min; Riley, Jonathan P.; Yang, Hsiu-Chiung; Reynolds, Nichole A.; Kahl, Steven D.; Lewis, Anjana Patel; Groshong, Christopher; Madsen, Russell E.; Conners, Kris; Lineswala, Jayana P.; Gheyi, Tarun; Saflor, Melbert-Brian Decipulo; Lee, Matthew R.; Benach, Jordi; Baker, Kenton A.; Montrose-Rafizadeh, Chahrzad; Genin, Michael J.; Miller, Anne R.; Hamdouchi, Chafiq 分享 收藏
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Structural Determinants of the γ-8 TARP Dependent AMPA Receptor Antagonist Lee, Matthew R.; Gardinier, Kevin M.; Gernert, Douglas L.; Schober, Douglas A.; Wright, Rebecca A.; Wang, He; Qian, Yuewei; Witkin, Jeffrey M.; Nisenbaum, Eric S.; Kato, Akihiko S. 分享 收藏
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism Kato, Akihiko S.; Burris, Kevin D.; Gardinier, Kevin M.; Gernert, Douglas L.; Porter, Warren J.; Reel, Jon; Ding, Chunjin; Tu, Yuan; Schober, Douglas A.; Lee, Matthew R.; Heinz, Beverly A.; Fitch, Thomas E.; Gleason, Scott D.; Catlow, John T.; Yu, Hong; Fitzjohn, Stephen M.; Pasqui, Francesca; Wang, He; Qian, Yuewei; Sher, Emanuele; Zwart, Ruud; Wafford, Keith A.; Rasmussen, Kurt; Ornstein, Paul L.; Isaac, John T. R.; Nisenbaum, Eric S.; Bredt, David S.; Witkin, Jeffrey M. 分享 收藏
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling 嘌呤基吡啶基氨基dfg-in/α c-螺旋out b-raf抑制剂: 将突变体与野生型b-raf选择性指数应用于化合物分析 Liu, Longbin; Lee, Matthew R.; Kim, Joseph L.; Whittington, Douglas A.; Bregman, Howard; Hua, Zihao; Lewis, Richard T.; Martin, Matthew W.; Nishimura, Nobuko; Potashman, Michele; Yang, Kevin; Yi, Shuyan; Vaida, Karina R.; Epstein, Linda F.; Babij, Carol; Fernando, Manory; Carnahan, Josette; Norman, Mark H. 分享 收藏
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