Ursula Fearon - Publications, H-index & Citations

Ursula Fearon

Trinity College Dublin

65H指数

323论文数

1.2W被引数

收录论文 144

发表时间

Hypoxia as an amplifier of synovial inflammation in rheumatoid arthritis 缺氧作为类风湿关节炎中滑膜炎症的放大器

Nature Reviews Rheumatology

IF32.7

2026-07-22

PREAI

Mary Canavan; Orla Tynan; Jean Fletcher; Ursula Fearon

JAK/STAT inhibition reprograms T cell activation and metabolism in inflammatory arthritis patients JAK/STAT抑制重编程炎症性关节炎患者T细胞的活化和代谢

Inflammation Research

IF5.4

2026-05-05

OAAI

Viviana Marzaioli; Aenea A. I. Brugman; Niamh O’Dowd; Achilleas Floudas; Aine Gorman; Carl Orr; Douglas J. Veale; Ursula Fearon

Synovial Tissue Macrophage Heterogeneity in Rheumatoid Arthritis 类风湿关节炎滑膜组织巨噬细胞异质性

European Journal of Immunology

IF3.7

2026-01-01

PREAI

Hanlon, Megan M.; Fearon, Ursula; Gravallese, Ellen M.

Immune cell-derived cytokines synergistically interact to drive synovial fibroblast invasive function and metabolic capacity 免疫细胞来源的细胞因子协同作用，驱动滑膜成纤维细胞的侵袭功能和代谢能力。

Journal of Autoimmunity

IF7

2025-12-22

PREAI

Órla Tynan; Alyssa Gilmore; Aenea A.I. Brugman; Achilleas Floudas; Conor M. Smith; Dumitru Anton; Siobhán Wade; Carl Orr; Douglas J. Veale; Ursula Fearon

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function 线粒体ABHD11抑制驱动甾醇代谢以调节T细胞效应功能

Nature Communications

IF15.7

2025-11-03

OAAI

Benjamin J. Jenkins; Yasmin R. Jenkins; Fernando M. Ponce-Garcia; Chloe Moscrop; Iain A. Perry; Matthew D. Hitchings; Alejandro H. Uribe; Federico Bernuzzi; Simon Eastham; James G. Cronin; Ardena Berisha; Alexandra Howell; Joanne Davies; Julianna Blagih; Marta Williams; Morgan Marsden; Douglas J. Veale; Luke C. Davies; Micah Niphakis; David K. Finlay; Linda V. Sinclair; Benjamin F. Cravatt; Andrew E. Hogan; James A. Nathan; Ian R. Humphreys; Ursula Fearon; David Sumpton; Johan Vande Voorde; Goncalo Dias do Vale; Jeffrey G. McDonald; Gareth W. Jones; James A. Pearson; Emma E. Vincent; Nicholas Jones

Loss of synovial tissue macrophage homeostasis precedes rheumatoid arthritis clinical onset

SCIENCE ADVANCES

IF12.5

2024-09-27

OAAI

Hanlon, Megan M.; Smith, Conor M.; Canavan, Mary; Neto, Nuno G. B.; Song, Qingxuan; Lewis, Myles J.; O'Rourke, Aoife M.; Tynan, Orla; Barker, Brianne E.; Gallagher, Phil; Mullan, Ronan; Hurson, Conor; Moran, Barry; Monaghan, Michael G.; Pitzalis, Costantino; Fletcher, Jean M.; Nagpal, Sunil; Veale, Douglas J.; Fearon, Ursula

ANALYSIS OF SERUM BIOMARKERS IN THE DIAGNOSIS AND MONITORING OF DISEASE ACTIVITY IN PSORIATIC ARTHRITIS 银屑病关节炎中血清生物标志物在疾病诊断和活动性监测中的分析

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2024-06-01

PREAI

Sundanum, S.; Marzaioli, V.; Anton, D.; Darcy, H.; Gallagher, P.; Orr, C.; Fearon, U.; Veale., D.

CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis CD200成纤维细胞在关节炎中形成促分辨的间充质网络

NATURE IMMUNOLOGY

IF27.6

2024-02-23

OAAI

Rauber, Simon; Mohammadian, Hashem; Schmidkonz, Christian; Atzinger, Armin; Soare, Alina; Treutlein, Christoph; Kemble, Samuel; Mahony, Christopher B.; Geisthoff, Manuel; Angeli, Mario R.; Raimondo, Maria G.; Xu, Cong; Yang, Kai-Ting; Lu, Le; Labinsky, Hannah; Saad, Mina S. A.; Gwellem, Charles A.; Chang, Jiyang; Huang, Kaiyue; Kampylafka, Eleni; Knitza, Johannes; Bilyy, Rostyslav; Distler, Joerg H. W.; Hanlon, Megan M.; Fearon, Ursula; Veale, Douglas J.; Roemer, Frank W.; Bauerle, Tobias; Maric, Hans M.; Maschauer, Simone; Ekici, Arif B.; Buckley, Christopher D.; Croft, Adam P.; Kuwert, Torsten; Prante, Olaf; Canete, Juan D.; Schett, Georg; Ramming, Andreas

A new class of 7-deazaguanine agents targeting autoimmune diseases: dramatic reduction of synovial fibroblast IL-6 production from human rheumatoid arthritis patients and improved performance against murine experimental autoimmune encephalomyelitis

RSC MEDICINAL CHEMISTRY

IF3.6

2024-01-01

OAAI

Cotter, Michelle; Quinn, Shauna M.; Fearon, Ursula; Ansboro, Sharon; Rakovic, Tatsiana; Southern, John M.; Kelly, Vincent P.; Connon, Stephen J.

Type I Interferons induce endothelial destabilization in Systemic Lupus Erythematosus in a Tie2-dependent manner I型干扰素以Tie2-dependent方式诱导系统性红斑狼疮的内皮细胞不稳定

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-12-14

OAAI

Rafael-Vidal, Carlos; Martinez-Ramos, Sara; Malvar-Fernandez, Beatriz; Altabas-Gonzalez, Irene; Mourino, Coral; Veale, Douglas J.; Floudas, Achilleas; Fearon, Ursula; Reigosa, Jose Maria Pego; Garcia, Samuel

Therapeutic Effects of Mesenchymal/Stromal Stem Cells and Their Derived Extracellular Vesicles in Rheumatoid Arthritis 间充质/基质干细胞及其衍生的细胞外囊泡对类风湿关节炎的治疗作用

STEM CELLS TRANSLATIONAL MEDICINE

IF4.9

2023-11-02

OAAI

Tsiapalis, Dimitrios; Floudas, Achilleas; Tertel, Tobias; Boerger, Verena; Giebel, Bernd; Veale, Douglas J.; Fearon, Ursula; O'Driscoll, Lorraine

Cardiovascular risk and systemic inflammation in male professional rugby: a cross-sectional study

BMJ OPEN SPORT & EXERCISE MEDICINE

IF3.2

2023-11-01

OAAI

Mchugh, Cliodhna; Hind, Karen; Kelly, Aine; Fearon, Ursula; Wasfy, Meagan; Floudas, Achilleas; Barad, Zsuzsanna; Dane, Kathryn; Farrell, Gareth; Wilson, Fiona

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity Canagliflozin通过自身免疫中的代谢抑制损害T细胞效应子功能

CELL METABOLISM

IF30.9

2023-07-01

OAAI

Jenkins, Benjamin J.; Blagih, Julianna; Ponce-Garcia, Fernando M.; Canavan, Mary; Gudgeon, Nancy; Eastham, Simon; Hill, David; Hanlon, Megan M.; Ma, Eric H.; Bishop, Emma L.; Rees, April; Cronin, James G.; Jury, Elizabeth C.; Dimeloe, Sarah K.; Veale, Douglas J.; Thornton, Catherine A.; Vousden, Karen H.; Finlay, David K.; Fearon, Ursula; Jones, Gareth W.; Sinclair, Linda, V; Vincent, Emma E.; Jones, Nicholas

The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis 雷帕霉素的哺乳动物靶标有助于类风湿关节炎滑膜成纤维细胞的致病性

FRONTIERS IN MEDICINE

IF3

2023-02-03

OAAI

Barker, Brianne E.; Hanlon, Megan M.; Marzaioli, Viviana; Smith, Conor M.; Cunningham, Clare C.; Fletcher, Jean M.; Veale, Douglas J.; Fearon, Ursula; Canavan, Mary

Cellular metabolic adaptations in rheumatoid arthritis and their therapeutic implications

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2022-04-19

PREAI

Fearon, Ursula; Hanlon, Megan M.; Floudas, Achilleas; Veale, Douglas J.

Central Role of Semaphorin 3B in a Serum-Induced Arthritis Model and Reduced Levels in Patients With Rheumatoid Arthritis

ARTHRITIS & RHEUMATOLOGY

IF10.9

2022-04-13

OAAI

Igea, Ana; Carvalheiro, Tiago; Malvar-Fernandez, Beatriz; Martinez-Ramos, Sara; Rafael-Vidal, Carlos; Niemantsverdriet, Ellis; Varade, Jezabel; Fernandez-Carrera, Andrea; Jimenez, Norman; McGarry, Trudy; Rodriguez-Trillo, Angela; Veale, Douglas; Fearon, Ursula; Conde, Carmen; Pego-Reigosa, Jose M.; Gonzalez-Fernandez, Africa; Reedquist, Kris A.; Radstake, Timothy R. D. J.; van der Helm-Van Mil, Annette; Garcia, Samuel

Inside the Joint of Inflammatory Arthritis Patients: Handling and Processing of Synovial Tissue Biopsies for High Throughput Analysis

FRONTIERS IN MEDICINE

IF3

2022-03-14

OAAI

Floudas, Achilleas; Gorman, Aine; Neto, Nuno; Monaghan, Michael G.; Elliott, Zoe; Fearon, Ursula; Marzaioli, Viviana

CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting 类风湿和银屑病关节炎患者的CD209/CD14树突状细胞特征: 激活，滑膜浸润和治疗靶向

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-01-12

OAAI

Marzaioli, Viviana; Canavan, Mary; Floudas, Achilleas; Flynn, Keelin; Mullan, Ronan; Veale, Douglas J.; Fearon, Ursula