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Alexandre Theocharides

University Hospital Zurich
H指数:27
被引数:2,788

个人简介

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教育背景

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工作经历

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荣誉奖项

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A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy

卵巢癌肿瘤谱分析资源：化疗驱动的异质性及个性化治疗策略的洞见

Nature Communications
IF15.7
2026-07-130
OAAI
Francis Jacob; Rebekka Wegmann; Joanna Ficek-Pascual; Ulrike Lischetti; Jack Kuipers; Stéphane Chevrier; Michael Prummer; Nora C. Toussaint; Ilaria Alborelli; Ricardo Coelho; Ruben Casanova; Sandra Goetze; Gabriele Gut; Monica-Andreea Baciu-Drăgan; Anne Bertolini; Ximena Bonilla; Jon Brugger; Magdalena M. Brune; Byron Calgua; Stefanie Engler; Cinzia Esposito; Pedro F. Ferreira; Andrea Jacobs; Flavio C. Lombardo; Paola Malsot; Julien Mena; Nicola Miglino; Emanuela S. Milani; Jacobo Sarabia Del Castillo; Sujana Sivapatham; Bettina A. Sobottka-Brillout; Tanmay Tanna; Tibor A. Zwimpfer; Rudolf Aebersold; Marina Bacac; Niko Beerenwinkel; Christian Beisel; Bernd Bodenmiller; Viktor H. Koelzer; Kjong-Van Lehmann; Mitchell P. Levesque; Holger Moch; Simone Muenst; Lucas Pelkmans; Markus G. Manz; Gunnar Rätsch; Franziska Singer; Berend Snijder; Alexandre P. A. Theocharides; Markus Tolnay; Andreas Wicki; Bernd Wollscheid; Viola Heinzelmann-Schwarz
CAR T-cells targeting CD117 effectively eliminate mast cells in preclinical models of advanced systemic mastocytosis

靶向CD117的CAR T细胞在先进系统性肥大细胞增多症的临床前模型中有效清除肥大细胞

Leukemia
IF13.4
2026-05-070
OAAI
Anne Kaiser; Veronika Lysenko; Renier Myburgh; Laura Volta; Christian Pellegrino; Alexandre P. A. Theocharides; Deborah Christen; Jens Panse; Marco M. Bühler; Michel Arock; Joseph Butterfield; Marcelo A. S. de Toledo; Peter Valent; Martin Zenke; Tim H. Brümmendorf; Markus G. Manz
Kupffer cells are key mediators of antigen-specific immune tolerance by peptide-coupled red blood cells

库普弗细胞通过肽偶联红细胞是抗原特异性免疫耐受的关键介质

Science Advances
IF12.5
2026-01-010
PRE
Vasileia Kalaitzaki; Pietro Oldrati; Filipa M. Ferreira; Antonis Katsoulas; Ahmed Ali; Livio Baselgia; Boping Liu; Jincheng Fang; Roman Sankowski; Mai Matsushita; Florence Vallelian; Alexandre P. A. Theocharides; Cyrill Géraud; Roland Martinꝉ; Andreas Lutterotti; Thorsten Buch
Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia

急性髓系白血病中先天性和获得性药物耐药性的单细胞景观

Nature Communications
IF15.7
2024-10-300
OAAI
Rebekka Wegmann; Ximena Bonilla; Ruben Casanova; Stéphane Chevrier; Ricardo Coelho; Cinzia Esposito; Joanna Ficek-Pascual; Sandra Goetze; Gabriele Gut; Francis Jacob; Andrea Jacobs; Jack Kuipers; Ulrike Lischetti; Julien Mena; Emanuela S. Milani; Michael Prummer; Jacobo Sarabia Del Castillo; Franziska Singer; Sujana Sivapatham; Nora C. Toussaint; Oliver Vilinovszki; Mattheus H. E. Wildschut; Tharshika Thavayogarajah; Disha Malani; Rudolf Aebersold; Marina Bacac; Niko Beerenwinkel; Christian Beisel; Bernd Bodenmiller; Viola Heinzelmann-Schwarz; Viktor H. Koelzer; Mitchell P. Levesque; Holger Moch; Lucas Pelkmans; Gunnar Rätsch; Markus Tolnay; Andreas Wicki; Bernd Wollscheid; Markus G. Manz; Berend Snijder; Alexandre P. A. Theocharides
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
EMBO MOLECULAR MEDICINE
IF8.3
2024-07-302
OAAI
Losa, Marco; Emmenegger, Marc; De Rossi, Pierre; Schuerch, Patrick M.; Serdiuk, Tetiana; Pengo, Niccolo; Capron, Danaelle; Bieli, Dimitri; Bargenda, Niklas; Rupp, Niels J.; Carta, Manfredi C.; Frontzek, Karl J.; Lysenko, Veronika; Reimann, Regina R.; Schwarz, Petra; Nuvolone, Mario; Westermark, Gunilla T.; Nilsson, K. Peter R.; Polymenidou, Magdalini; Theocharides, Alexandre P. A.; Hornemann, Simone; Picotti, Paola; Aguzzi, Adriano
Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells

靶向甲羟戊酸或Wnt途径以克服TP53-mutant AML细胞中的CAR T细胞抗性

EMBO MOLECULAR MEDICINE
IF8.3
2024-02-143
OAAI
Mueller, Jan; Schimmer, Roman R.; Koch, Christian; Schneiter, Florin; Fullin, Jonas; Lysenko, Veronika; Pellegrino, Christian; Klemm, Nancy; Russkamp, Norman; Myburgh, Renier; Volta, Laura; Theocharides, Alexandre P. A.; Kurppa, Kari J.; Ebert, Benjamin L.; Schroeder, Timm; Manz, Markus G.; Boettcher, Steffen
Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis
NATURE COMMUNICATIONS
IF15.7
2023-10-124
OAAI
Wildschut, Mattheus H. E.; Mena, Julien; Dordelmann, Cyril; van Oostrum, Marc; Hale, Benjamin D.; Settelmeier, Jens; Festl, Yasmin; Lysenko, Veronika; Schurch, Patrick M.; Ring, Alexander; Severin, Yannik; Bader, Michael S.; Pedrioli, Patrick G. A.; Goetze, Sandra; van Drogen, Audrey; Balabanov, Stefan; Skoda, Radek C.; Lopes, Massimo; Wollscheid, Bernd; Theocharides, Alexandre P. A.; Snijder, Berend
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms
NATURE CANCER
IF28.5
2023-08-076
OAAI
Grockowiak, Elodie; Korn, Claudia; Rak, Justyna; Lysenko, Veronika; Hallou, Adrien; Panvini, Francesca M.; Williams, Matthew; Fielding, Claire; Fang, Zijian; Khatib-Massalha, Eman; Garcia-Garcia, Andres; Li, Juan; Khorshed, Reema A.; Gonzalez-Anton, Sara; Baxter, E. Joanna; Kusumbe, Anjali; Wilkins, Bridget S.; Green, Anna; Simons, Benjamin D.; Harrison, Claire N.; Green, Anthony R.; Lo Celso, Cristina; Theocharides, Alexandre P. A.; Mendez-Ferrer, Simon
Bone marrow haematopoiesis in patients with COVID-19
HISTOPATHOLOGY
IF4.1
2023-06-140
OA
Marques-Maggio, Ewerton; Maccio, Umberto; Marx, Alexandra; Galli, Serena; Schwab, Nathalie; Frank, Angela; Hamelin, Baptiste; Varga, Zsuzsanna; Nombela-Arrieta, Cesar; Mertz, Kirsten D.; Theocharides, Alexandre P. A.; Koelzer, Viktor H.
An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein
CELL REPORTS
IF6.9
2021-06-016
OAAI
Kara, Eleanna; Crimi, Alessandro; Wiedmer, Anne; Emmenegger, Marc; Manzoni, Claudia; Bandres-Ciga, Sara; D'Sa, Karishma; Reynolds, Regina H.; Botia, Juan A.; Losa, Marco; Lysenko, Veronika; Carta, Manfredi; Heinzer, Daniel; Avar, Merve; Chincisan, Andra; Blauwendraat, Cornelis; Garcia-Ruiz, Sonia; Pease, Daniel; Mottier, Lorene; Carrella, Alessandra; Beck-Schneider, Dezirae; Magalhaes, Andreia D.; Aemisegger, Caroline; Theocharides, Alexandre P. A.; Fan, Zhanyun; Marks, Jordan D.; Hopp, Sarah C.; Abramov, Andrey Y.; Lewis, Patrick A.; Ryten, Mina; Hardy, John; Hyman, Bradley T.; Aguzzi, Adriano

研究方向

暂未获取到该数据
M
Markus G. Manz
H 指数:79论文数:601被引数:3.1万
V
Veronika Lysenko
H 指数:11论文数:42被引数:474
P
Patrick M. Schürch
H 指数:8论文数:21被引数:201
M
Mattheus H. E. Wildschut
H 指数:11论文数:19被引数:561
N
Nicole Wildner-Verhey van Wijk
H 指数:6论文数:13被引数:143
A
Alexandar Tzankov
H 指数:80论文数:771被引数:3.4万
B
Bernd Wollscheid
H 指数:56论文数:234被引数:1.2万
S
Stefan Balabanov
H 指数:35论文数:167被引数:4,738
A
Adriano Aguzzi
H 指数:123论文数:883被引数:6.1万
H
Holger Moch
H 指数:118论文数:1,126被引数:7.0万