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C

C. Bruce Verchere

University of British Columbia

55H指数
252论文数
1.0W被引数
收录论文 131
发表时间
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Manipulation of Gene Expression in Mouse Pancreas via Intraductal Delivery of Adeno-Associated Viral Vectors通过腺相关病毒载体经导管递送调控小鼠胰腺基因表达
errBIO-PROTOCOL
IF1.1
err2026-04-20
err0
PREAI
errSoukhatcheva, Galina; Stanley, Liam; Dai, Lei; Komba, Mitsuhiro; Andriiets, Volodymyr; Johnson, James D.; Verchere, C. Bruce; Chen, Yi-Chun
err分享
err收藏
Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists肽基-甘氨酸α-酰胺化单加氧酶中的2型糖尿病风险等位基因影响GLP-1水平以及对GLP-1受体激动剂的反应
errGenome Medicine
IF11.2
err2026-03-29
err0
errOAAI
errMahesh M. Umapathysivam; Elisa Araldi; Benoit Hastoy; Adem Y. Dawed; Hasan Vatandaslar; Johanna E. Mayrhofer; Peter Lindquist; Pamuditha N. Silva; Algera Goga; Geraldine O. Trüllinger; Svenja Godbersen; Shahana Sengupta; Adrian Kaufmann; Søren Krogsgaard Thomsen; Bolette Hartmann; Yi-Chun Chen; Anna E. Jonsson; Hasan Kabakci; Swaraj Thaman; Niels Grarup; Christian T. Have; Lindsay P. Pallo; Kristine Faerch; Anette P. Gjesing; Sameena Nawaz; Jane Cheeseman; Matthew J. Neville; Oluf Pedersen; Mark Walker; Han Sun; Christopher Jennison; Andrew T. Hattersley; Jens F. Rehfeld; Rury R. Holman; Bruce C. Verchere; Torben Hansen; Fredrik Karpe; Jens J. Holst; Mette M. Rosenkilde; Angus G. Jones; Michael Ristow; Mark I. McCarthy; Ewan R. Pearson; Markus Stoffel; Anna L. Gloyn
err分享
err收藏
Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice胰岛淀粉样蛋白破坏MHC class II抗原呈递并延缓NOD小鼠的自身免疫性糖尿病
errDiabetologia
IF10.2
err2025-12-22
err0
errOAAI
errHeather C. Denroche; Victoria Ng; Jane Velghe; Imelda Suen; Liam Stanley; Dominika Nackiewicz; Mitsuhiro Komba; Derek L. Dai; Galina Soukhatcheva; Sam Chen; C. Bruce Verchere
err分享
err收藏
Insulin production is sustained during DNA damage-mediated senescence in adult human beta cells在DNA损伤介导的衰老过程中，成年人体β细胞的胰岛素产生得以维持。
errDiabetologia
IF10.2
err2025-11-13
err0
errOAAI
errCamille Préfontaine; Jasmine Pipella; Nayara Rampazzo Morelli; Yi-Chun Chen; C. Bruce Verchere; Peter J. Thompson
err分享
err收藏
P.27: Generating amyloid resistant stem cell-derived beta cells to improve islet transplant outcomes in type 1 diabetes.P.27: 生成抗淀粉样变性的人干细胞来源的β细胞，以改善1型糖尿病中的胰岛移植效果。
errTransplantation
IF5
err2025-10-20
err0
PREAI
errKar, Saumadritaa; Orban, Paul C.; Sasaki, Shugo; Dai, Derek; Soukhatcheva, Galina; Lynn, Francis C.; Verchere, Bruce C.
err分享
err收藏
α cells use both PC1/3 and PC2 to process proglucagon peptides and control insulin secretionα细胞使用PC1/3和PC2来处理前胰高血糖素肽并控制胰岛素分泌。
errScience Advances
IF12.5
err2025-09-19
err0
errOAAI
errCanqi Cui; Danielle C. Leander; Sarah M. Gray; Kimberley El; Alex Chen; Paul A. Grimsrud; Jessica O. Becker; Austin Taylor; Guo-Fang Zhang; Kyle W. Sloop; C. Bruce Verchere; Andrew N. Hoofnagle; David A. D’Alessio; Jonathan E. Campbell
err分享
err收藏
Persisting plasma proinsulin levels in a cohort of 482 individuals with long-standing type 1 diabetes mellitus长期1型糖尿病人群中持续升高的血浆前胰岛素水平
errdiabetes obesity metabolism
IF0
err2025-07-14
err0
errOAAI
errDouwe Frank de Wit MD; Coco Marjolein Fuhri Snethlage MD; Rana Minab MSc; Elena Rampanelli PhD; Pleun de Groen BSc; Manon Balvers PhD; Timothy James McDonald PhD; Richard A. Oram PhD; Bart O. Roep PhD; Daniel H. van Raalte MD; Cameron Bruce Verchere PhD; Max Nieuwdorp MD; Nordin M. J. Hanssen MD
err分享
err收藏
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication局部GLP1受体预内化指导胰腺α细胞与β细胞之间的通信
errCell Metabolism
IF30.9
err2025-07-14
err0
errOAAI
errJason C.L. Tong; Charlotte Frazer-Morris; Ali H. Shilleh; Katrina Viloria; Anne de Bray; Adithya Muraleedaran Nair; Paul R.V. Johnson; Rebecca Spiers; Ahmad Kobiita; Oladapo E. Olaniru; Shanta J. Persaud; Robert Hauffe; André Kleinridders; Carsten Schultz; C. Bruce Verchere; Canqi Cui; Jonathan E. Campbell; Malgorzata Cyranka; Alexey Epanchintsev; Carina Ämmälä; Johannes Broichhagen; David J. Hodson
err分享
err收藏
Cell therapy with human interleukin 10–producing ILC2s enhances islet function and inhibits allograft rejection人白细胞介素10产生型ILC2s的细胞疗法可增强胰岛功能并抑制同种异体移植物排斥。
errAmerican Journal of Transplantation
IF8.2
err2025-05-23
err0
errOAAI
errSarah J. Colpitts; Sinthuja Jegatheeswaran; Amanda Oakie; Siavash Mashhouri; Nadia Sachewsky; Humaira Murshed; Jessica A. Mathews; Kyle T. Reid; Paraish S. Misra; Vivian C.W. Fung; Trevor W. Reichman; M. Cristina Nostro; C.Bruce Verchere; Megan K. Levings; Sarah Q. Crome
err分享
err收藏
Inhibition of xanthine oxidoreductase with febuxostat, but not allopurinol, prevents inflammasome assembly and IL-1β release使用febuxostat而非allopurinol抑制黄嘌呤氧化还原酶，可阻止炎症小体组装和IL-1β的释放。
errLIFE SCIENCE ALLIANCE
IF2.9
err2025-05-21
err0
errOAAI
errMonteiro, Lauar de Brito; Archambault, Anne-Sophie; Starchuk, Lucas F.; Alcazar, Armando; Oh, Ju Hee; Dubland, Joshua A.; Rakic, Bojana; Patterson, Annette E.; Verchere, C. Bruce; Geltink, Ramon I. Klein
err分享
err收藏
Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing global translation inhibition真核翻译起始因子2A在内质网应激期间保护胰腺β细胞，同时挽救全局翻译抑制
errDIABETOLOGIA
IF10.2
err2025-04-30
err0
PREAI
errPanzhinskiy, Evgeniy; Skovso, Sos; Cen, Haoning Howard; Rahardjo, Amanda; Zhang, Jiashuo Aaron; Chu, Kwan Yi; Macdonald, Kate; Soukhatcheva, Galina; Dionne, Derek A.; Hallmaier-Wacker, Luisa K.; Wildi, Jennifer S.; Marcil, Stephanie; Noursadeghi, Nilou; Taghizadeh, Farnaz; Verchere, C. Bruce; Jan, Eric; Johnson, James D.
err分享
err收藏
Advances in Engineering Myeloid Cells for Cell Therapy Applications工程化骨髓细胞在细胞治疗中的应用进展
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-12-26
err0
PREAI
errFreitas, Bruno F. A.; Verchere, C. Bruce; Levings, Megan K.
err分享
err收藏
An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell- derived insulin producing cells
errMOLECULAR METABOLISM
IF6.6
err2024-11-01
err0
errOAAI
errBayly, Carmen L.; Dai, Xiao-Qing; Nian, Cuilan; Orban, Paul C.; Verchere, C. Bruce; MacDonald, Patrick E.; Lynn, Francis C.
err分享
err收藏
Quantitative analysis of islet prohormone convertase 1/3 expression in human pancreas donors with diabetes糖尿病人类胰腺供体中胰岛前激素转化酶1/3表达的定量分析
errDIABETOLOGIA
IF10.2
err2024-10-15
err0
errOAAI
errApaolaza, Paola S.; Chen, Yi-Chun; Grewal, Kavi; Lurz, Yannik; Boulassel, Severin; Verchere, C. Bruce; Rodriguez-Calvo, Teresa
err分享
err收藏
Purine catabolism regulates the production of IL-1beta in macrophages
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errArchambault, Anne-Sophie; Monteiro, Lauar de Brito; Starchuck, Lucas; Oh, Juhee; Perraso, Emilia; Patterson, Annette; Verchere, C. Bruce; Geltink, Ramon Klein
err分享
err收藏
Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing
errENDOCRINOLOGY
IF3.3
err2023-11-15
err2
errOAAI
errFulcher, James M.; Swensen, Adam C.; Chen, Yi-Chun; Verchere, C. Bruce; Petyuk, Vladislav A.; Qian, Wei-Jun
err分享
err收藏
A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models
errNATURE COMMUNICATIONS
IF15.7
err2023-10-09
err8
errOAAI
errWirth, Fabian; Heitz, Fabrice D.; Seeger, Christine; Combaluzier, Ioana; Breu, Karin; Denroche, Heather C.; Thevenet, Julien; Osto, Melania; Arosio, Paolo; Kerr-Conte, Julie; Verchere, C. Bruce; Pattou, Francois; Lutz, Thomas A.; Donath, Marc Y.; Hock, Christoph; Nitsch, Roger M.; Grimm, Jan
err分享
err收藏
Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice具有MHC II类肽特异性嵌合抗原受体的Tregs预防小鼠自身免疫性糖尿病
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-08-10
err22
errOAAI
errSpanier, Justin A.; Fung, Vivian; Wardell, Christine M.; Alkhatib, Mohannad H.; Chen, Yixin; Swanson, Linnea A.; Dwyer, Alexander J.; Weno, Matthew E.; Silva, Nubia; Mitchell, Jason S.; Orban, Paul C.; Mojibian, Majid; Verchere, C. Bruce; Fife, Brian T.; Levings, Megan K.
err分享
err收藏
Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes
errDIABETES CARE
IF16.6
err2023-08-03
err6
errOAAI
errSnethlage, Coco M. Fuhri; Mcdonald, Timothy J.; Oram, Richard D.; de Groen, Pleun; Rampanelli, Elena; Schimmel, Alinda W. M.; Holleman, Frits; Siegelaar, Sarah; Hoekstra, Joost; Brouwer, Catherine B.; Knop, Filip K.; Verchere, C. Bruce; van Raalte, Daniel H.; Roep, Bart O.; Nieuwdorp, Max; Hanssen, Nordin M. J.
err分享
err收藏
Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in MiceΒ 细胞中羧肽酶E的缺失会破坏胰岛素原的加工，但不会导致小鼠糖尿病的自发发展。
errDIABETES
IF7.5
err2023-06-26
err5
errOAAI
errChen, Yi-Chun; Taylor, Austin J.; Fulcher, James M.; Swensen, Adam C.; Dai, Xiao-Qing; Komba, Mitsuhiro; Wrightson, Kenzie L. C.; Fok, Kenny; Patterson, Annette E.; Klein Geltink, Ramon I.; MacDonald, Patrick E.; Qian, Wei-Jun; Verchere, C. Bruce
err分享
err收藏

研究方向

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