Gregory G. Germino - Publications, H-index & Citations

Gregory G. Germino

national institutes of health

64H指数

174论文数

1.5W被引数

收录论文 68

发表时间

Deletion of ARPKD-associated Pkhd1 gene in mice results in decreased Tfap2b expression and eye abnormalities 敲除与ARPKD相关的Pkhd1基因导致小鼠Tfap2b表达降低和眼部异常

Nature Communications

IF15.7

2026-07-23

OAAI

Yu Ishimoto; Luis F. Menezes; Naoki Nakaya; Karla Barbosa-Sabanero; Yukihiro Horie; Teruhiko Yoshida; Jeff M. Reece; Fang Zhou; Stanislav Tomarev; Laura Kerosuo; Gregory G. Germino

A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts 一种新的ARPKD小鼠模型，其多囊肾和肝病1 (Pkhd1) 基因组位点几乎完全缺失，具有多种表型，但没有肾囊肿

KIDNEY INTERNATIONAL

IF12.6

2023-09-01

OAAI

Ishimoto, Yu; Menezes, Luis F.; Zhou, Fang; Yoshida, Teruhiko; Komori, Taishi; Qiu, Jiahe; Young, Marian F.; Lu, Huiyan; Potapova, Svetlana; Outeda, Patricia; Watnick, Terry; Germino, Gregory G.

Polycystin-1 Regulates Extracellular Signal-Regulated Kinase-Dependent Phosphorylation of Tuberin To Control Cell Size through mTOR and Its Downstream Effectors S6K and 4EBP1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

185

OAAI

Distefano, Gianfranco; Boca, Manila; Rowe, Isaline; Wodarczyk, Claas; Ma, Li; Piontek, Klaus B.; Germino, Gregory G.; Pandolfi, Pier Paolo; Boletta, Alessandra

Pkd1 Mutation Has No Apparent Effects on Peroxisome Structure or Lipid Metabolism

KIDNEY360

IF3

2021-10-28

OAAI

Terabayashi, Takeshi; Menezes, Luis F.; Zhou, Fang; Cai, Hongyi; Walter, Peter J.; Garraffo, Hugo M.; Germino, Gregory G.

Pathway identification through transcriptome analysis

CELLULAR SIGNALLING

IF3.7

2020-10-01

OAAI

Terabayashi, Takeshi; Germino, Gregory G.; Menezes, Luis F.

The pathobiology of polycystic kidney disease from a metabolic viewpoint

NATURE REVIEWS NEPHROLOGY

IF39.8

2019-09-05

PREAI

Menezes, Luis Fernando; Germino, Gregory G.

A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed

SCIENTIFIC REPORTS

IF3.9

2018-02-09

OAAI

Lin, Cheng-Chao; Kurashige, Mahiro; Liu, Yi; Terabayashi, Takeshi; Ishimoto, Yu; Wang, Tanchun; Choudhary, Vineet; Hobbs, Ryan; Liu, Li-Ka; Lee, Ping-Hsien; Outeda, Patricia; Zhou, Fang; Restifo, Nicholas P.; Watnick, Terry; Kawano, Haruna; Horie, Shigeo; Prinz, William; Xu, Hong; Menezes, Luis F.; Germino, Gregory G.

A Report of the 24th Annual Congress on Women's HealthWorkshop on Transforming Women's Health: From Research to Practice

JOURNAL OF WOMENS HEALTH

IF1.9

2018-01-01

OAAI

Plank-Bazinet, Jennifer L.; Sampson, Annie; Kornstein, Susan G.; Germino, Gregory G.; Robert-Guroff, Marjorie; Gilman, Stephen E.; Wetherington, Cora Lee; Cook, Nakela; Cornelison, Terri L.; Begg, Lisa; Clayton, Janine Austin

A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism 常染色体隐性多囊肾的新型模型质疑纤维囊肿蛋白C-末端在疾病机制中的作用

KIDNEY INTERNATIONAL

IF12.6

2017-11-01

OAAI

Outeda, Patricia; Menezes, Luis; Hartung, Erum A.; Bridges, Stacey; Zhou, Fang; Zhu, Xianjun; Xu, Hangxue; Huang, Qiong; Yao, Qin; Qian, Feng; Germino, Gregory G.; Watnick, Terry

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology 由于PKHD1/Pkhd1缺陷导致的NEDD4-family E3连接酶功能障碍提示了ARPKD病理生物学的机制模型

SCIENTIFIC REPORTS

IF3.9

2017-08-10

OAAI

Kaimori, Jun-ya; Lin, Cheng-Chao; Outeda, Patricia; Garcia-Gonzalez, Miguel A.; Menezes, Luis F.; Hartung, Erum A.; Li, Ao; Wu, Guanqing; Fujita, Hideaki; Sato, Yasunori; Nakanuma, Yasuni; Yamamoto, Satoko; Ichimaru, Naotsugu; Takahara, Shiro; Isaka, Yoshitaka; Watnick, Terry; Onuchic, Luiz F.; Guay-Woodford, Lisa M.; Germino, Gregory G.

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease

EBIOMEDICINE

IF10.8

2016-03-01

137

OAAI

Menezes, Luis F.; Lin, Cheng-Chao; Zhou, Fang; Germino, Gregory G.

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism

NATURE COMMUNICATIONS

IF15.7

2014-11-18

106

OAAI

Kim, Hyunho; Xu, Hangxue; Yao, Qin; Li, Weizhe; Huang, Qiong; Outeda, Patricia; Cebotaru, Valeriu; Chiaravalli, Marco; Boletta, Alessandra; Piontek, Klaus; Germino, Gregory G.; Weinman, Edward J.; Watnick, Terry; Qian, Feng

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2014-10-01

OAAI

Lee, Yin Loon; Sante, Joshua; Comerci, Colin J.; Cyge, Benjamin; Menezes, Luis F.; Li, Feng-Qian; Germino, Gregory G.; Moerner, W. E.; Takemaru, Ken-Ichi; Stearns, Tim

Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development

CELL REPORTS

IF6.9

2014-05-01

OAAI

Outeda, Patricia; Huso, David L.; Fisher, Steven A.; Halushka, Marc K.; Kim, Hyunho; Qian, Feng; Germino, Gregory G.; Watnick, Terry

POLYCYSTIC KIDNEY DISEASE Polycystin-1 and polycystin-2-it's complicated

NATURE REVIEWS NEPHROLOGY

IF39.8

2013-04-09

PREAI

Watnick, Terry J.; Germino, Gregory G.

Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier

PLOS GENETICS

IF3.7

2012-11-29

OAAI

Menezes, Luis F.; Zhou, Fang; Patterson, Andrew D.; Piontek, Klaus B.; Krausz, Kristopher W.; Gonzalez, Frank J.; Germino, Gregory G.

Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1

HUMAN MOLECULAR GENETICS

IF3.2

2012-09-21

OAAI

Foy, Rebecca L.; Chitalia, Vipul C.; Panchenko, Maria V.; Zeng, Liling; Lopez, Delia; Lee, Jean W.; Rana, Shaunak V.; Boletta, Alessandra; Qian, Feng; Tsiokas, Leonidas; Piontek, Klaus B.; Germino, Gregory G.; Zhou, Mina I.; Cohen, Herbert T.

A missense mutation in PKD1 attenuates the severity of renal disease

KIDNEY INTERNATIONAL

IF12.6

2012-02-01

OAAI

Pei, York; Lan, Zheng; Wang, Kairong; Garcia-Gonzalez, Miguel; He, Ning; Dicks, Elizabeth; Parfrey, Patrick; Germino, Gregory; Watnick, Terry

T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease

KIDNEY INTERNATIONAL

IF12.6

2011-07-01

OAAI

Miller, Michelle M.; Iglesias, Diana M.; Zhang, Zhao; Corsini, Rachel; Chu, LeeLee; Murawski, Inga; Gupta, Indra; Somlo, Stefan; Germino, Gregory G.; Goodyer, Paul R.

Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-05-27

OAAI

Ferreira, Frederico M.; Oliveira, Leandro C.; Germino, Gregory G.; Onuchic, Jose N.; Onuchic, Luiz F.

研究方向