Jeffrey A. Toretsky - Publications, H-index & Citations

Jeffrey A. Toretsky

Georgetown University Medical Center

55H指数

339论文数

1.0W被引数

收录论文 102

发表时间

PAX3::FOXO1-Targeting PROTAC Induces Myogenic Differentiation of Fusion-Positive Rhabdomyosarcoma Cells PAX3::FOXO1靶向PROTAC诱导融合阳性横纹肌肉瘤细胞的肌源性分化

Cancers

IF4.4

2026-07-24

OAAI

Nikola Knoll; Kayra Somay; Purushottam B. Tiwari; Emre Deniz; Jeffrey S. S. K. Formen; Isabel Frye; Eryn Nelson; Christian Wolf; Jeffrey A. Toretsky; Aykut Üren

Exploring Resistance to ETS Targeting Agents in Diffuse Large B-Cell Lymphoma 探索弥漫性大B细胞淋巴瘤对ETS靶向药物的耐药性

Cancer Medicine

IF3.1

2026-05-13

OAAI

Spriano, Filippo; Cascione, Luciano; Tarantelli, Chiara; Sartori, Giulio; Arribas, Alberto J.; Velasova, Adriana; Napoli, Sara; Havranek, Ondrej; Toretsky, Jeffrey A.; Bertoni, Francesco

The unphosphorylated; closed form of ezrin binds to RNA to maintain a metastatic phenotype in osteosarcoma cells 非磷酸化；闭合状态的ezrin与RNA结合，以维持骨肉瘤细胞中的转移表型

Science Signaling

IF6.6

2026-03-17

PREAI

Emre Deniz; Prakriti Tiwari; Purushottam B. Tiwari; Eric Glasgow; Brent T. Harris; Anup Tiwari; Chunyan Hou; Junfeng Ma; Jeffrey A. Toretsky; Aykut Üren

A Novel FLI1 Monoclonal Antibody Which Recognizes EWS::FLI1 with High Affinity Is Useful for Detecting Ewing Sarcoma 一种新型FLI1单克隆抗体，能够高亲和力识别EWS::FLI1，可用于检测尤文氏肉瘤

Antibodies 2025, Vol. 14, Page 97

IF2.7

2025-11-10

OAAI

Saravana P. Selvanathan; Olivia O. Lansinger; David V. Allegakoen; Emma J. W. McGuire; Ashley R. Gaffey; Jeff R. Petro; Purushottam B. Tiwari; Quinn Tufiño; Aykut Üren; Jeffrey A. Toretsky

RETRACTION: Retraction: Combining PARP-1 Inhibition and Radiation in Ewing Sarcoma Results in Lethal DNA Damage

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-11-04

PREAI

Lee, Hae-June; Yoon, Changhwan; Schmidt, Benjamin; Park, Do Joong; Zhang, Alexia Y.; Erkizan, Hayriye V.; Toretsky, Jeffrey A.; Kirsch, David G.; Yoon, Sam S.

Small molecule inhibitors of the PAX3::FOXO1 fusion protein in rhabdomyosarcoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Shaw, Taryn; Nakazawa, Kay; Tiwari, Purushottam; Nelson, Eryn; Formen, Jeffrey; Wolf, Christian; Toretsky, Jeffrey; Uren, Aykut

In vivo CRISPR/Cas9 transcriptional activation screen leads to discovery of INAFM2, a novel driver of metastasis

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Molotkova, Anna; Deniz, Emre; Swift, Matthew; Glasgow, Eric; Toretsky, Jeffrey; Uren, Aykut

USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity

MOLECULAR CANCER

IF33.9

2023-12-13

OAAI

Kwon, Juntae; Zhang, Jinmin; Mok, Boram; Allsup, Samuel; Kim, Chul; Toretsky, Jeffrey; Han, Cecil

Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3-and c-Jun n-terminal kinase-dependent mechanism

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

100

OAAI

Endo, Yoshimi; Beauchamp, Elspeth; Woods, David; Taylor, William G.; Toretsky, Jeffrey A.; Uren, Aykut; Rubin, Jeffrey S.

Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Celik, Haydar; Sajwan, Kamal P.; Selvanathan, Saravana P.; Marsh, Benjamin J.; Pai, Amrita V.; Kont, Yasemin Saygideger; Han, Jenny; Minas, Tsion Z.; Rahim, Said; Erkizan, Hayriye Verda; Toretsky, Jeffrey A.; Ueren, Aykut

Widespread hypertranscription in aggressive human cancers

SCIENCE ADVANCES

IF12.5

2022-11-23

OAAI

Zatzman, Matthew; Fuligni, Fabio; Ripsman, Ryan; Suwal, Tannu; Comitani, Federico; Edward, Lisa-Monique; Denroche, Rob; Jang, Gun Ho; Notta, Faiyaz; Gallinger, Steven; Selvanathan, Saravana P.; Toretsky, Jeffrey A.; Hellmann, Matthew D.; Tabori, Uri; Huang, Annie; Shlien, Adam

An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma

NPJ PRECISION ONCOLOGY

IF8

2022-09-17

OAAI

Shulman, David S.; Whittle, Sarah B.; Surdez, Didier; Bailey, Kelly M.; de Alava, Enrique; Yustein, Jason T.; Shlien, Adam; Hayashi, Masanori; Bishop, Alexander J. R.; Crompton, Brian D.; DuBois, Steven G.; Shukla, Neerav; Leavey, Patrick J.; Lessnick, Stephen L.; Kovar, Heinrich; Delattre, Olivier; Gruenewald, Thomas G. P.; Antonescu, Cristina R.; Roberts, Ryan D.; Toretsky, Jeffrey A.; Tirode, Franck; Gorlick, Richard; Janeway, Katherine A.; Reed, Damon; Lawlor, Elizabeth R.; Grohar, Patrick J.

Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations 结合脂质标记和点击化学可以隔离细胞外囊泡，以无创检测致癌基因的改变

ADVANCED SCIENCE

IF14.1

2022-03-09

OAAI

Sun, Na; Tran, Benjamin, V; Peng, Zishan; Wang, Jing; Zhang, Ceng; Yang, Peng; Zhang, Tiffany X.; Widjaja, Josephine; Zhang, Ryan Y.; Xia, Wenxi; Keir, Alexandra; She, Jia-Wei; Yu, Hsiao-hua; Shyue, Jing-Jong; Zhu, Hongguang; Agopian, Vatche G.; Pei, Renjun; Tomlinson, James S.; Toretsky, Jeffrey A.; Jonas, Steven J.; Federman, Noah; Lu, Shaohua; Tseng, Hsian-Rong; Zhu, Yazhen

Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma

NAR CANCER

IF3.2

2022-01-14

OAAI

Graham, Garrett T.; Selvanathan, Saravana P.; Zoellner, Stefan K.; Stahl, Emily; Shlien, Adam; Caplen, Natasha J.; Uren, Aykut; Toretsky, Jeffrey A.

O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-07-26

PREAI

Nosella, Michael L.; Tereshchenko, Maria; Pritisanac, Iva; Chong, P. Andrew; Toretsky, Jeffrey A.; Lee, Hyun O.; Forman-Kay, Julie D.

Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response 靶向DDX3X通过dsRNA介导的肿瘤内在I型干扰素反应触发抗肿瘤免疫

CANCER RESEARCH

IF16.6

2021-05-03

OAAI

Choi, Hyeongjwa; Kwon, Juntae; Cho, Min Soon; Sun, Yifan; Zheng, Xiaofeng; Wang, Jing; Bouker, Kerrie B.; Casey, John L.; Atkins, Michael B.; Toretsky, Jeffrey; Han, Cecil

Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives

JOURNAL OF CLINICAL MEDICINE

IF2.9

2021-04-14

131

OAAI

Zoellner, Stefan K.; Amatruda, James E.; Bauer, Sebastian; Collaud, Stephane; de Alava, Enrique; DuBois, Steven G.; Hardes, Jendrik; Hartmann, Wolfgang; Kovar, Heinrich; Metzler, Markus; Shulman, David S.; Streitbuerger, Arne; Timmermann, Beate; Toretsky, Jeffrey A.; Uhlenbruch, Yasmin; Vieth, Volker; Gruenewald, Thomas G. P.; Dirksen, Uta

Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies 将纳米结构微芯片与共价化学偶联，可以纯化肉瘤衍生的细胞外囊泡，用于下游功能研究

ADVANCED FUNCTIONAL MATERIALS

IF19

2020-09-13

OAAI

Dong, Jiantong; Zhang, Ryan Y.; Sun, Na; Hu, Junhui; Smalley, Matthew D.; Zhou, Anqi; Hua, Yue; Rothermich, Winston; Chen, Mengxiang; Chen, Jiayuan; Ye, Jinglei; Teng, Pai-Chi; Qi, Dongping; Toretsky, Jeffrey A.; Tomlinson, James S.; Li, Mengyuan; Weiss, Paul S.; Jonas, Steven J.; Federman, Noah; Wu, Lily; Zhao, Meiping; Tseng, Hsian-Rong; Zhu, Yazhen

Phase I study of TK216, a novel anti-ETS agent for Ewing sarcoma

ANNALS OF ONCOLOGY

IF65.4

2020-09-01

OAAI

Ludwig, J. A.; Federman, N.; Anderson, P.; Macy, M. E.; Davis, L. E.; Riedel, R. F.; Muscal, J. A.; Daw, N. C.; Ratan, R.; Toretsky, J.; Ianopulos, X.; Hsu, F. J.; Breitmeyer, J. B.; Meyers, P.

A novel PARD3B-NUTM1 fusion in an aggressive primary CNS embryonal tumor in a young adult

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2020-07-17

OAAI

Ko, Kyungmin; Kitani, Takashi; Harris, Brent T.; Anaizi, Amjad N.; Solomon, David; Perry, Arie; Toretsky, Jeffrey; Ozdemirli, Metin

研究方向