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Pratyaksha Wirapati

University of Geneva
H指数:32
被引数:9,275

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Driving tumor-associated macrophages to a CXCL9Hi/SPP1Low phenotype eliminates pancreatic cancer

将肿瘤相关巨噬细胞驱动至CXCL9高表达/SPP1低表达表型可消除胰腺癌

Cell Reports Medicine
IF10.6
2026-07-230
OA
Yen T.M. Nguyen; Marc Pfefferlé; Juhyun Oh; Grant G. Simpson; Sierra A. Walker; Shingo Noguchi; Christopher S. Garris; Riley J. Deutsch-Williams; Pratyaksha Wirapati; Federico De Stefano; Marie Goemans; Rui Dai; Claudio Vinegoni; Carlos Fernández del Castillo; Andrew S. Liss; Mikael J. Pittet; Ralph Weissleder
Mast-cell derived nerve growth factor drives ILC2 pro-tumoral functions in bladder cancer

肥大细胞来源的神经营养因子驱动膀胱癌中ILC2的促肿瘤功能

Nature Communications
IF15.7
2026-02-210
OAAI
Maryline Falquet; Hajar El Ahanidi; Alejandra Gomez-Cadena; Ziyang Su; Anthony Cornu; Tania Wyss; Burak Kizil; Robert Pick; Katayoun Falamaki; Pratyaksha Wirapati; Benedetta Fiordi; Isis Senoner; Daniela Claudia Maresca; Neil Kallal; Danaé Guedj; Mario Kreutzfeldt; Jean-Christophe Tille; Marine M. Leblond; Katarzyna Michaud; Silvia Pesce; Simona Candiani; Korneliusz Golebski; Julien Dagher; Melinda Charrier; Caroline Pressacco Brossier; Elisabeth Grobet-Jeandin; Romina Marone; Stéphanie Hugues; Lukas T. Jeker; Grégory Verdeil; Doron Merkler; Emanuela Marcenaro; Christoph Scheiermann; Mohammed Attaleb; Daniel Benamran; Petros Tsantoulis; Giuseppe Ercolano; Sara Trabanelli; Camilla Jandus
CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

CCL3由跨癌症的老年中性粒细胞产生并促进肿瘤生长

Cancer Cell
IF44.5
2026-02-050
OAAI
Evangelia Bolli; Pratyaksha Wirapati; Mehdi Hicham; Yuxuan Xie; Marie Siwicki; Florent Duval; Anne-Gaëlle Goubet; Máté Kiss; Béatrice Zitti; Thomas Zwahlen; Sheri Mcdowell; Ruben Bill; Simona Angerani; Camilla Engblom; Seth Anderson; Aiping Jiang; Oliver Hartley; David B. Sykes; Maja Jankovic; Nadine Fournier
Exploratory biomarker analysis of RAS/BRAF somatic mutations and gene expression signatures for predicting treatment effects of aflibercept in the velour trial

RAS/BRAF体细胞突变和基因表达特征在velour试验中预测 aflibercept治疗效果的探索性生物标志物分析

npj Precision Oncology
IF8
2026-01-130
OAAI
Ting Pu; Allyson M. Peddle; Pratyaksha Wirapati; Petros Tsantoulis; Qian Wu; Yourae Hong; Leslie Samuel; Jayesh Desai; Maigo Riener; Zacharenia Saridaki; David Cunningham; Sabine Tejpar
Integrative analysis of transcriptomic data reveals a predictive gene signature for chemoradiotherapy response in rectal cancer

转录组数据的整合分析揭示了预测直肠癌化疗放疗反应的基因特征

iScience
IF4.1
2025-12-170
OAAI
Claudia Corrò; Joao Victor Machado Carvalho; Melivoia Rapti; Paolo Angelino; Matthieu Tihy; Arnaud Bakaric; Giacomo Puppa; Pratyaksha Wirapati; André Durham; Frederic Ris; Stephanie Tissot; Jonathan Thevenet; Inti Zlobec; Valérie Dutoit; Mikael Pittet; Petros Tsantoulis; Thibaud Koessler
Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation

通过多组询问揭示了人类原发性和转移性脑肿瘤中T细胞的表型多样性

NATURE CANCER
IF28.5
2023-05-2219
OAAI
Wischnewski, Vladimir; Maas, Roeltje R.; Aruffo, Paola Guerrero; Soukup, Klara; Galletti, Giovanni; Kornete, Mara; Galland, Sabine; Fournier, Nadine; Lilja, Johanna; Wirapati, Pratyaksha; Lourenco, Joao; Scarpa, Alice; Daniel, Roy T.; Hottinger, Andreas F.; Brouland, Jean-Philippe; Losurdo, Agnese; Voulaz, Emanuele; Alloisio, Marco; Hegi, Monika E.; Lugli, Enrico; Joyce, Johanna A.
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers

<i>CXCL9:SPP1</i> 巨噬细胞极性识别控制人类癌症的细胞程序网络

Science
IF45.8
2023-01-010
OA
Ruben Bill; Pratyaksha Wirapati; Marius Messemaker; Whijae Roh; Béatrice Zitti; Florent Duval; Máté Kiss; Jong Chul Park; Talia M. Saal; Jan Hoelzl; David Tarussio; Fabrizio Benedetti; Stéphanie R. Tissot; Lana Elias Kandalaft; Marco Varrone; Giovanni Ciriello; Thomas McKee; Yan Monnier; Maxime Mermod; Emily M. Blaum; Irena Gushterova; Anna L. K. Gonye; Nir Hacohen; Gad A. Getz; Thorsten R. Mempel; Allon Moshe Klein; Ralph Weissleder; William C. Faquin; Peter M. Sadow; Derrick T. Lin; Sara Isabel Pai; Moshe Sade-Feldman; Mikaël J. Pittet
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia (vol 29, pg 1213, 2022)
CELL STEM CELL
IF20.4
2022-11-010
OA
Vazquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

结肠直肠肿瘤中动态和适应性的癌症干细胞群混合

CELL STEM CELL
IF20.4
2022-08-0146
OAAI
Vasquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
NATURE GENETICS
IF31.8
2022-06-30139
OAAI
Joanito, Ignasius; Wirapati, Pratyaksha; Zhao, Nancy; Nawaz, Zahid; Yeo, Grace; Lee, Fiona; Eng, Christine L. P.; Macalinao, Dominique Camat; Kahraman, Merve; Srinivasan, Harini; Lakshmanan, Vairavan; Verbandt, Sara; Tsantoulis, Petros; Gunn, Nicole; Venkatesh, Prasanna Nori; Poh, Zhong Wee; Nahar, Rahul; Oh, Hsueh Ling Janice; Loo, Jia Min; Chia, Shumei; Cheow, Lih Feng; Cheruba, Elsie; Wong, Michael Thomas; Kua, Lindsay; Chua, Clarinda; Nguyen, Andy; Golovan, Justin; Gan, Anna; Lim, Wan-Jun; Guo, Yu Amanda; Yap, Choon Kong; Tay, Brenda; Hong, Yourae; Chong, Dawn Qingqing; Chok, Aik-Yong; Park, Woong-Yang; Han, Shuting; Chang, Mei Huan; Seow-En, Isaac; Fu, Cherylin; Mathew, Ronnie; Toh, Ee-Lin; Hong, Lewis Z.; Skanderup, Anders Jacobsen; DasGupta, Ramanuj; Ong, Chin-Ann Johnny; Lim, Kiat Hon; Tan, Emile K. W.; Koo, Si-Lin; Leow, Wei Qiang; Tejpar, Sabine; Prabhakar, Shyam; Tan, Iain Beehuat
Zeb2 drives invasive and microbiota-dependent colon carcinoma (vol 1, pg 620, 2020)
NATURE CANCER
IF28.5
2020-07-101
OAAI
Slowicka, Karolina; Petta, Ioanna; Blancke, Gillian; Hoste, Esther; Dumas, Emilie; Sze, Mozes; Vikkula, Hanna; Radaelli, Enrico; Haigh, Jody J.; Jonckheere, Sven; Taminau, Joachim; Vandamme, Niels; Wullaert, Andy; Tulchinsky, Eugene; Nittner, David; Van Vlierberghe, Pieter; De Hertogh, Gert; Baldin, Pamela; Etlioglu, Emre; Wirapati, Pratyaksha; Boon, Louis; Lambrecht, Bart N.; Callewaert, Chris; Tejpar, Sabine; Goossens, Steven; Berx, Geert; Vereecke, Lars; van Loo, Geert
Zeb2 drives invasive and microbiota-dependent colon carcinoma
NATURE CANCER
IF28.5
2020-06-1539
PREAI
Slowicka, Karolina; Petta, Ioanna; Blancke, Gillian; Hoste, Esther; Dumas, Emilie; Sze, Mozes; Vikkula, Hanna; Radaelli, Enrico; Haigh, Jody J.; Jonckheere, Sven; Taminau, Joachim; Vandamme, Niels; Wullaert, Andy; Tulchinsky, Eugene; Nittner, David; Van Vlierberghe, Pieter; De Hertogh, Gert; Baldin, Pamela; Etlioglu, Emre; Wirapati, Pratyaksha; Boon, Louis; Lambrecht, Bart N.; Callewaert, Chris; Tejpar, Sabine; Goossens, Steven; Berx, Geert; Vereecke, Lars; van Loo, Geert
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

谱系依赖性基因表达程序影响结直肠癌的免疫景观

NATURE GENETICS
IF31.8
2020-05-25403
PREAI
Lee, Hae-Ock; Hong, Yourae; Etlioglu, Hakki Emre; Cho, Yong Beom; Pomelle, Valentina; Van den Bosch, Ben; Vanhecke, Jasper; Verbandt, Sara; Hong, Hyekyung; Min, Jae-Woong; Kim, Nayoung; Eum, Hye Hyeon; Qian, Junbin; Boeckx, Bram; Lambrechts, Diether; Tsantoulis, Petros; De Hertogh, Gert; Chung, Woosung; Lee, Taeseob; An, Minae; Shin, Hyun-Tae; Joung, Je-Gun; Jung, Min-Hyeok; Ko, Gunhwan; Wirapati, Pratyaksha; Kim, Seok Hyung; Kim, Hee Cheol; Yun, Seong Hyeon; Tan, Iain Bee Huat; Ranjan, Bobby; Lee, Woo Yong; Kim, Tae-You; Choi, Jung Kyoon; Kim, Young-Joon; Prabhakar, Shyam; Tejpar, Sabine; Park, Woong-Yang

研究方向

暂未获取到该数据
S
Sabine Tejpar
H 指数:77论文数:498被引数:4.0万
M
Mauro Delorenzi
H 指数:86论文数:439被引数:4.2万
P
Petros Tsantoulis
H 指数:24论文数:316被引数:3,354
M
Mikäel J. Pittet
H 指数:92论文数:402被引数:5.1万
C
Christos Sotiriou
H 指数:122论文数:1,108被引数:7.9万
M
Martine Piccart
H 指数:149论文数:1,553被引数:11.5万
B
Benjamin Haibe‐Kains
H 指数:90论文数:1,171被引数:3.9万
R
Ralph Weissleder
H 指数:200论文数:1,603被引数:17.1万
J
Jonas Bergh
H 指数:103论文数:942被引数:7.0万
S
Sherene Loi
H 指数:126论文数:1,217被引数:7.9万