Niren Murthy - Publications, H-index & Citations

Niren Murthy

University of California System

59H指数

215论文数

1.6W被引数

收录论文 121

发表时间

Charge-switching ionizable lipids lower the toxicity of lipid nanoparticles 电荷转换型可离子化脂质可降低脂质纳米粒的毒性

Nature Nanotechnology

IF34.9

2026-09-08

OAAI

Dengpan Liang; Yalin Qi; Hesong Han; Negar Ahmadian; Kewa Gao; Kaycee Sapasap; Yuxi Zhang; Silin Guo; Atip Lawanprasert; Sopida Pimcharoen; Sheng Zhao; Milan T. Del Buono; He Xia; Zoe O. Enders; Benjamin W. Burgstone; Antonino Calio; Neel Dankar; Bingwei Lu; Lei S. Qi; Aijun Wang; Niren Murthy

Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding Publisher Correction: 靶向癌症特异性突变，利用RNA触发的染色质切碎

Nature

IF48.5

2026-08-14

PREAI

Jingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna

Redox-activated cholesterol-dependent cytolysin enables cytosolic release of liposomal cargo 氧化还原活化的胆固醇依赖性细胞溶素可促进脂质体载物的细胞质释放

International Journal of Biological Macromolecules

IF8.5

2026-07-01

PREAI

Jang, Seonhye; Pardeshi, Kundansingh; Shin, Suyeon; Jeong, ByeongJun; Zhao, Sheng; Qi, Yalin; Kim, Sung Tae; Park, Min Chul; Murthy, Niren; Kim, Hansol

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding 利用RNA触发的染色质降解靶向癌症特异性突变

Nature

IF48.5

2026-06-08

PREAI

Characterizing and controlling CRISPR repair outcomes in nondividing human cells 表征和控制非分裂人类细胞中的CRISPR修复结果

Nature Communications

IF15.7

2025-11-17

OAAI

Gokul N. Ramadoss; Samali J. Namaganda; Manasi M. Kumar; Jennifer R. Hamilton; Rohit Sharma; Karena G. Chow; Luke A. Workley; Bria L. Macklin; Mengyuan Sun; Alvin S. Ha; Jia-Cheng Liu; Christof Fellmann; Hannah L. Watry; Philip H. Dierks; Rudra S. Bose; Julianne Jin; Barbara S. Perez; Cindy R. Sandoval Espinoza; Madeline P. Matia; Serena H. Lu; Luke M. Judge; Brian R. Shy; Andre Nussenzweig; Britt Adamson; Niren Murthy; Jennifer A. Doudna; Martin Kampmann; Bruce R. Conklin

A microphysiological system for screening lipid nanoparticle−mRNA complexes predicts in vivo heart transfection efficacy 一种微生理系统用于筛选脂质纳米颗粒−mRNA复合物，可预测体内心脏转染效率

Nature Biomedical Engineering

IF26.6

2025-11-03

PREAI

Gabriel Neiman; Mauro W. Costa; Hesong Han; Sheng Zhao; Tammy K. Ng; Brian Siemons; Tomohiro Nishino; Yu Huang; Shyam Lal; Kenneth Wu; Luke M. Judge; Bruce R. Conklin; Deepak Srivastava; Niren Murthy; Kevin E. Healy

SYSTEMATIC IDENTIFICATION OF LIPID NANOPARTICLES FOR MRNA-BASED EPIGENETIC AND IMMUNE GLIOBLASTOMA THERAPIES 系统性鉴定用于mRNA介导的表观遗传学和免疫性胶质母细胞瘤治疗的脂质纳米颗粒

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Ma, Zerong; Sharma, Rohit; Lawanprasert, Atip; Lin, Katie; Sengelmann, Sasha; Hubbard, Akane; Phillips, Joanna; Berger, Mitchel; Murthy, Niren; Liu, S. John

Correction: Identification of acrylamide-based covalent inhibitors of SARS-CoV-2 (SCoV-2) Nsp15 using high-throughput screening and machine learning 更正：使用高通量筛选和机器学习方法鉴定丙烯酰胺基共价抑制剂对SARS-CoV-2（SCoV-2）Nsp15的作用

RSC Adv.

IF4.6

2025-08-22

OAAI

Teena Bajaj; Babak Mosavati; Lydia H. Zhang; Mohammad S. Parsa; Huanchen Wang; Evan M. Kerek; Xueying Liang; Seyed Amir Tabatabaei Dakhili; Eddie Wehri; Silin Guo; Rushil N. Desai; Lauren M. Orr; Mohammad R. K. Mofrad; Julia Schaletzky; John R. Ussher; Xufang Deng; Robin Stanley; Basil P. Hubbard; Daniel K. Nomura; Niren Murthy

EGFR Affibody and PEG functionalized protein nanoparticles: Sustaining targeting and macrophage evasion EGFR Affibody和PEG功能化蛋白质纳米粒：维持靶向和巨噬细胞逃逸

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-05-01

PREAI

Jang, Seonhye; Jun, Heejin; Eom, Soomin; Zhao, Sheng; Murthy, Niren; Kang, Sebyung; Kim, Hansol

Advances in acid-degradable and enzyme-cleavable linkers for drug delivery 用于药物输送的酸降解和酶裂解接头的研究进展

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2025-02-01

PREAI

Zhao, Sheng; Yu, Na; Han, Hesong; Guo, Shutao; Murthy, Niren

Identification of acrylamide-based covalent inhibitors of SARS-CoV-2 (SCoV-2) Nsp15 using high-throughput screening and machine learning 通过高通量筛选和机器学习鉴定丙烯酰胺基共价抑制SARS-CoV-2（SCoV-2）Nsp15的抑制剂

RSC ADVANCES

IF4.6

2025-01-01

OAAI

Bajaj, Teena; Mosavati, Babak; Zhang, Lydia H.; Parsa, Mohammad S.; Wang, Huanchen; Kerek, Evan M.; Liang, Xueying; Tabatabaei Dakhili, Seyed Amir; Wehri, Eddie; Guo, Silin; Desai, Rushil N.; Orr, Lauren M.; Mofrad, Mohammad R. K.; Schaletzky, Julia; Ussher, John R.; Deng, Xufang; Stanley, Robin; Hubbard, Basil P.; Nomura, Daniel K.; Murthy, Niren

Widespread Gene Editing in the Brain via In Utero Delivery of mRNA Using Acid-Degradable Lipid Nanoparticles 使用酸降解的脂质纳米颗粒通过子宫内递送mRNA在大脑中广泛进行基因编辑

ACS NANO

IF16

2024-10-24

OAAI

Gao, Kewa; Han, Hesong; Cranick, Matileen G.; Zhao, Sheng; Xu, Shanxiu; Yin, Boyan; Song, Hengyue; Hu, Yibo; Clarke, Maria T.; Wang, David; Wong, Jessica M.; Zhao, Zehua; Burgstone, Benjamin W.; Farmer, Diana L.; Murthy, Niren; Wang, Aijun

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 ribonucleoprotein 通过脂质纳米颗粒递送稳定的CRISPR-Cas9核糖核蛋白进行肺和肝编辑

NATURE BIOTECHNOLOGY

IF41.7

2024-10-16

OAAI

Chen, Kai; Han, Hesong; Zhao, Sheng; Xu, Bryant; Yin, Boyan; Lawanprasert, Atip; Trinidad, Marena; Burgstone, Benjamin W.; Murthy, Niren; Doudna, Jennifer A.

Acid-degradable lipid nanoparticles enhance the delivery of mRNA 酸降解脂质纳米粒增强mRNA的递送

NATURE NANOTECHNOLOGY

IF34.9

2024-08-23

PREAI

Zhao, Sheng; Gao, Kewa; Han, Hesong; Stenzel, Michael; Yin, Boyan; Song, Hengyue; Lawanprasert, Atip; Nielsen, Josefine Eilso; Sharma, Rohit; Arogundade, Opeyemi H.; Pimcharoen, Sopida; Chen, Yu-Ju; Paul, Abhik; Tuma, Jan; Collins, Michael G.; Wyle, Yofiel; Cranick, Matileen Grace; Burgstone, Benjamin W.; Perez, Barbara S.; Barron, Annelise E.; Smith, Andrew M.; Lee, Hye Young; Wang, Aijun; Murthy, Niren

HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing

VIRUSES-BASEL

IF3.5

2023-10-28

OAAI

Lyons, Danielle E.; Kumar, Priti; Roan, Nadia R.; Defechereux, Patricia A.; Feschotte, Cedric; Lange, Ulrike C.; Murthy, Niren; Sameshima, Pauline; Verdin, Eric; Ake, Julie A.; Parsons, Matthew S.; Nath, Avindra; Gianella, Sara; Smith, Davey M.; Kallas, Esper G.; Villa, Thomas J.; Strange, Richard; Mwesigwa, Betty; Furler O'Brien, Robert L.; Nixon, Douglas F.; Ndhlovu, Lishomwa C.; Valente, Susana T.; Ott, Melanie

Gene editing therapeutics based on mRNA delivery 基于mRNA传递的基因编辑疗法

ADVANCED DRUG DELIVERY REVIEWS

IF17.6

2023-09-01

OAAI

Popovitz, Juliana; Sharma, Rohit; Hoshyar, Reyhane; Kim, Beob Soo; Murthy, Niren; Lee, Kunwoo

In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles 使用脂质纳米颗粒在子宫内将mRNA递送至心脏，diaphragm肌和肌肉

BIOACTIVE MATERIALS

IF20.3

2023-07-01

OAAI

Gao, Kewa; Li, Jie; Song, Hengyue; Han, Hesong; Wang, Yongheng; Yin, Boyan; Farmer, Diana L.; Murthy, Niren; Wang, Aijun

Recent advances in organic near-infrared ratiometric small-molecule fluorescent probes 有机近红外比率型小分子荧光探针的研究进展

COORDINATION CHEMISTRY REVIEWS

IF23.5

2023-07-01

PREAI

Qi, Ya-Lin; Li, Yun-Zhan; Tan, Ming-Jun; Yuan, Fang-Fang; Murthy, Niren; Duan, Yong-Tao; Zhu, Hai-Liang; Yang, Sheng-Yu

Dimensionless parameter predicts bacterial prodrug success

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2022-01-10

OAAI

Holt, Brandon Alexander; Tuttle, McKenzie; Xu, Yilin; Su, Melanie; Roise, Joachim J.; Wang, Xioajian; Murthy, Niren; Kwong, Gabriel A.

A self-immolative linker that releases thiols detects penicillin amidase and nitroreductase with high sensitivity via absorption spectroscopy

CHEMICAL COMMUNICATIONS

IF4.2

2022-01-01

OAAI

Espinoza, Eli M.; Roise, Joachim J.; He, Maomao; Li, I-Che; Agatep, Alvin K.; Udenyi, Patrick; Han, Hesong; Jackson, Nicole; Kerr, D. Lucas; Chen, Dake; Stentzel, Michael R.; Ruan, Emily; Riley, Lee; Murthy, Niren

研究方向