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Andrew B. West

Duke University
H指数:68
被引数:1.7万

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Discovery of a Chiral 2,4-Substituted Pyrrolo[2,3-d]pyrimidine as a Potent, Selective, and Orally Bioavailable LRRK2 Inhibitor

发现一种手性2,4-取代的吡咯并[2,3-d]嘧啶作为强效、选择性且口服生物利用的LRRK2抑制剂

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-05-120
PRE
Moukha-Chafiq, Omar; Malankhanova, Tuyana; Valiyaveettil, Jacob; Gupta, Vandana; Kezar, Hollis; Zhang, Sixue; Nguyen, Theresa H.; Karyakarte, Shuklendu; Zhang, Wei; Bhakat, Soumendranath; Galemmo, Robert A.; Ananthan, Subramaniam; Manuvakhova, Anna; Ross, Larry I.; Maddry, Joseph A.; Bostwick, Robert; Suto, Mark J.; West, Andrew; Augelli-Szafran, Corinne E.
Bioaccumulation of microplastics in decedent human brains (feb, 10.1038/s41591-024-03453-1, 2025)

微塑料在人脑中的生物累积（Feb, 10.1038/s41591-024-03453-1, 2025）

NATURE MEDICINE
IF50
2025-03-310
OA
Nihart, Alexander J.; Garcia, Marcus A.; El Hayek, Eliane; Liu, Rui; Olewine, Marian; Kingston, Josiah D.; Castillo, Eliseo F.; Gullapalli, Rama R.; Howard, Tamara; Bleske, Barry; Scott, Justin; Gonzalez-Estrella, Jorge; Gross, Jessica M.; Spilde, Michael; Adolphi, Natalie L.; Gallego, Daniel F.; Jarrell, Heather S.; Dvorscak, Gabrielle; Zuluaga-Ruiz, Maria E.; West, Andrew B.; Campen, Matthew J.
Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
SCIENCE ADVANCES
IF12.5
2024-11-010
OAAI
Sokratian, Arpine; Zhou, Ye; Tatli, Meltem; Burbidge, Kevin J.; Xu, Enquan; Viverette, Elizabeth; Donzelli, Sonia; Duda, Addison M.; Yuan, Yuan; Li, Huizhong; Strader, Samuel; Patel, Nirali; Shiell, Lauren; Malankhanova, Tuyana; Chen, Olivia; Mazzulli, Joseph R.; Perera, Lalith; Stahlberg, Henning; Borgnia, Mario; Bartesaghi, Alberto; Lashuel, Hilal A.; West, Andrew B.
A blood-based marker of mitochondrial DNA damage in Parkinson’s disease
Science Translational Medicine
IF14.6
2023-01-010
OAAI
Rui Qi; Esther M. Sammler; Claudia P. González-Hunt; Ivana Barraza; Nicholas Pena; Jeremy P. Rouanet; Yahaira Naaldijk; Steven D. Goodson; Marie Fuzzati; Fabio Blandini; Kirk I. Erickson; Andrea M. Weinstein; Michael William Lutz; John B. Kwok; Glenda Margaret Halliday; Nicolas L. Dzamko; Shalini Padmanabhan; Roy N. Alcalay; Cheryl Waters; Penelope Hogarth; Tanya Simuni; Danielle Smith; Connie Marras; Francesca Tonelli; Dario R. Alessi; Andrew B. West; Sruti Shiva; Sabine Hilfiker; Laurie H. Sanders
Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity
JOURNAL OF PARKINSONS DISEASE
IF5
2022-07-0812
OAAI
Fernandez, Belen; Chittoor-Vinod, Vinita G.; Kluss, Jillian H.; Kelly, Kaela; Bryant, Nicole; Nguyen, An Phu Tran; Bukhari, Syed A.; Smith, Nathan; Ordonez, Antonio Jesus Lara; Fdez, Elena; Chartier-Harlin, Marie-Christine; Montine, Thomas J.; Wilson, Mark A.; Moore, Darren J.; West, Andrew B.; Cookson, Mark R.; Nichols, R. Jeremy; Hilfiker, Sabine

研究方向

暂未获取到该数据
Z
Zhiyong Liu
H 指数:34论文数:127被引数:3,668
T
Ted M. Dawson
H 指数:160论文数:714被引数:10.2万
L
Laura A. Volpicelli‐Daley
H 指数:45论文数:108被引数:1.0万
D
Darren J. Moore
H 指数:58论文数:116被引数:2.0万
M
Mark S. Moehle
H 指数:19论文数:42被引数:2,519
V
Valina L. Dawson
H 指数:151论文数:584被引数:10.8万
V
Vedad Delic
H 指数:15论文数:48被引数:1,448
A
Arpine Sokratian
H 指数:7论文数:37被引数:585
N
Nicole Bryant
H 指数:13论文数:23被引数:1,217
K
Kyle Fraser
H 指数:17论文数:39被引数:2,671