Jóhann E. Guðjónsson - Publications, H-index & Citations

Jóhann E. Guðjónsson

university of michigan

80H指数

591论文数

2.7W被引数

收录论文 327

发表时间

Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasia, Inflammation, and Extracellular Matrix Markers in Patients With Moderate-to-Severe Atopic Dermatitis 胶带剥离转录组学揭示nemolizumab对中重度特应性皮炎患者瘙痒、增生、炎症和细胞外基质标志物的影响

Allergy

IF12

2026-09-05

PREAI

Daniel Liu; Ester Del Duca; Nicolas Delaleu; Megan Lau; Juliana Pulsinelli; Joel Correa de Rosa; Jonathan Bar; Yeriel Estrada; Johann Gudjonsson; Valerie Julia; Emma Guttman-Yassky

Investigating the molecular drivers of high-level clinical responses to bimekizumab in psoriatic disease: Introducing the BE UNIQUE phase 3b study 探究贝美克单抗在银屑病中高水平临床应答的分子驱动因素：介绍BE UNIQUE 3b期研究

Journal of Investigative Dermatology

IF5.7

2026-09-01

PREAI

Johann E. Gudjonsson; Joseph F. Merola; Richard B. Warren; Iain B. McInnes; Balint Szilagyi; Christiane Simon-Hinsberg; Paul Jones; Joe Rastrick; Ann Cleverly; Ioana Cutcutache; James G. Krueger

Single-cell transcriptome reveals keratinocyte subclusters contributing to altered differentiation and inflammatory responses in atopic dermatitis 单细胞转录组揭示特应性皮炎中参与分化改变和炎症反应的角质形成细胞亚群

Nature Communications

IF15.7

2026-07-14

OAAI

Tingting Qin; Rachael Bogle; Rundong Jiang; Mrinal K. Sarkar; Yuli Cai; Mehrnaz Gharaee-Kermani; Jennifer Fox; Xianying Xing; Sahiti Marella; Mio Nakamura; Emanual Maverakis; Stephanie T. Le; Alexander A. Merleev; Alina I. Marusina; Cory L. Simpson; Arti Parihar; Connor Hill; He Li; J. Michelle Kahlenberg; Dawn M. Waterworth; Nina Sabins; Lloyd S. Miller; Tom C. Freeman; Monica WL Leung; Marta E. Polak; Lam C. Tsoi; Allison C. Billi; Johann E. Gudjonsson

A single-cell atlas identifies oncogenic transcriptional programs and immune escape mechanisms in CTCL 单细胞图谱鉴定CTCL中的致癌转录程序和免疫逃逸机制

Blood

IF23.1

2026-07-02

PREAI

Chenguang Wang; Xiangrong Geng; Suhaib Abdelrahman; Yao Fu; Nermin Kady; Mohd A. Rauf; Alexandra Hristov; Trilokraj Tejasvi; Carlos Murga-Zamalloa; Lam C. Tsoi; Joshua Welch; Jennifer Fox; Shannon Carty; Johann E. Gudjonsson; Ryan A. Wilcox

A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit 纵向人类银屑病皮肤图谱揭示了抗IL-23疗法破坏型17炎症通路的机制

Immunity

IF26.3

2026-05-28

PREAI

Rundong Jiang; Andrew Blauvelt; Linyu Shi; Lam C. Tsoi; Rachael Bogle; Jennifer Fox; Mehrnaz Gharaee-Kermani; Lihong Chen; Haihan Zhang; Xianying Xing; Mrinal K. Sarkar; Olesya Plazyo; J. Michelle Kahlenberg; Allison C. Billi; Robert T. Matheson; Huzefa Photowala; Benjamin D. Ehst; Johann E. Gudjonsson

Keratin 16 inhibits type I interferon responses in differentiating keratinocytes of stressed and diseased skin Keratin 16 抑制应激和病变皮肤中分化角化细胞中的 I 型干扰素反应

Science Translational Medicine

IF14.6

2026-04-08

PREAI

Erez Cohen; Yang Xu; Sonal Ghodke; Amanda Orosco; Dajia Wang; Craig N. Johnson; Kaylee Steen; Mrinal K. Sarkar; Nurhan Özlü; Lam C. Tsoi; Johann E. Gudjonsson; Lucile Marchal; Alain Hovnanian; Carole A. Parent; Pierre A. Coulombe

Cellular And Molecular Landscape of Early Hidradenitis Suppurativa Lesions Reveals Early Immune Microenvironment 早期化脓性汗腺炎病灶的细胞与分子景观揭示早期免疫微环境

Journal of Investigative Dermatology

IF5.7

2026-03-28

OAAI

Stephan M. Caucheteux; Saeed Khalili; David Croitoru; Lily Acheampong; Johann E. Gudjonsson; Vincent Piguet

Seq-Scope-eXpanded: spatial omics beyond optical resolution Seq-Scope-eXpanded：超越光学分辨率的空间组学

Nature Communications

IF15.7

2026-02-10

OAAI

Angelo Anacleto; Weiqiu Cheng; Qianlu Feng; Anna Park; Chun-Seok Cho; Yongha Hwang; Yongsung Kim; Yichen Si; Jer-En Hsu; Qingyang Zhao; Xiaoya Zhao; Daniel Kim; Mitchell Schrank; Alex William Schrader; Seokjin Yeo; Rosane Teles; Robert L. Modlin; Olesya Plazyo; Johann E. Gudjonsson; Myungjin Kim; Chang H. Kim; Hee-Sun Han; Hyun Min Kang; Jun Hee Lee

Multimodal analyses of early, untreated systemic sclerosis skin identify a proinflammatory vascular niche of macrophage-fibroblast signaling 早期未经治疗的系统性硬化症皮肤的多模态分析识别出巨噬细胞-成纤维细胞信号传导的促炎血管微环境

JCI Insight

IF6.1

2026-02-09

PREAI

Jarnagin, Helen C.; Parvizi, Rezvan; Gong, Zhiyun; Gedert, Rosemary; Xing, Xianying; Tsoi, Lam (Alex) C.; Bogle, Rachael; Morrisson, Madeline J.; Perreard, Laurent; Pioli, Patricia A.; Kolling, Fred; Gudjonsson, Johann E.; Khanna, Dinesh; Whitfield, Michael L.

Spatial transcriptomics identifies differentiation, lipid metabolism, and retinoid pathway alterations in acne 空间转录组学鉴定痤疮中分化、脂质代谢和类视色素通路的变化

JCI Insight

IF6.1

2026-02-09

PREAI

Durgin, Joseph S.; Veniaminova, Natalia A.; Huyge, Thomas J.; Tsai, Shih-Ying; Fox, Jennifer; Cai, Yuli; Sarkar, Mrinal K.; Tsoi, Lam C.; Gudjonsson, Johann E.; Wong, Sunny Y.

Mechanisms of fibrotic tissue remodelling: insights from systemic sclerosis 纤维化组织重塑的机制: 系统性硬化症的见解

Nature Reviews Rheumatology

IF32.7

2026-01-26

PREAI

Jörg H. W. Distler; David Launay; Carol Feghali-Bostwick; Alexandru-Emil Matei; Maria Trojanowska; Johann E. Gudjonsson

Skin fibroblasts in health and disease: From extracellular matrix remodeling to immune regulation 健康与疾病中的皮肤成纤维细胞：从细胞外基质重塑到免疫调节

Journal of Investigative Dermatology

IF5.7

2026-01-05

PREAI

Sahiti Marella; Maksim Plikus; Johann E. Gudjonsson

Hidradenitis suppurativa: Why dose escalation often fails and what biology tells us about next steps 化脓性汗腺炎：为什么剂量递增常会失败以及生物学揭示了关于后续步骤的信息

Journal of Allergy and Clinical Immunology

IF11.2

2025-12-29

OAAI

Kelsey R. van Straalen; Johann E. Gudjonsson

Dermatomyositis is characterized by JAK1-mediated monocyte-driven vasculopathy and inflammation

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2025-12-24

PREAI

Osborne, Grace A.; Zhang, Lin; Ma, Feiyang; Gharaee-Kermani, Mehrnaz; Turnier, Jessica L.; Victory, Amanda N.; Hurst, Amy; Xu, Bin; Pedersen, Elisabeth A.; Bogle, Rachael; Berthier, Celine C.; Ognenovski, Vladimir; Nakamura, Mio; Tsoi, Lam C.; Billi, Allison C.; Gudjonsson, Johann E.; Klein, Benjamin; Tsou, Pei-Suen; Kahlenberg, J. Michelle

Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis 以IL-36/TNFSF15反应为中心的动态中性粒细胞-角化细胞通讯网络，表征了泛发性脓疱型银屑病中的炎症反应。

Nature Communications

IF15.7

2025-12-23

OAAI

Rundong Jiang; Joseph Kirma; Jennifer Fox; Xianying Xing; Jiaqi Wang; Mrinal K. Sarkar; Rachael Bogle; Tran Do; Anthony Coon; Christopher Cole; Olesya Plazyo; Joanna E. Rew; Haihan Zhang; J. Michelle Kahlenberg; Allison C. Billi; Hervé Bachelez; Lam C. Tsoi; Paul W. Harms; Shuai Shao; Xiang Chen; Johann E. Gudjonsson

IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3 IL-17A在糖尿病伤口中增加，并通过组蛋白去甲基化酶JMJD3损害角质形成细胞功能。

Nature Communications

IF15.7

2025-12-18

OAAI

Jadie Y. Moon; Sonya J. Wolf; Amrita D. Joshi; He Zhang; James Shadiow; Tyler M. Bauer; Kevin D. Mangum; Lindsey D. Hughes; Christopher O. Audu; William J. Melvin; Emily C. Barrett; Sabrina Rocco; Gabriela Saldana de Jimenez; Amber L. Estor; Moses Nelapudi; Qinmengge Li; Rachael Bogle; Benjamin Levi; Frank M. Davis; Andrea T. Obi; Bethany B. Moore; Lam C. Tsoi; Johann E. Gudjonsson; Katherine A. Gallagher

Single-cell and spatial transcriptomics implicate vascular cell orchestration of inflammatory changes after UV light exposure in skin 单细胞和空间转录组学揭示UV光照射后皮肤中血管细胞对炎症变化的调控

Journal of Investigative Dermatology

IF5.7

2025-12-17

PREAI

Jie An; Rachael Bogle; Rayan Najjar; Lam C. Tsoi; J. Michelle Kahlenberg; Ksenia Anufrieva; Erin Theisen; Kevin Wei; Johann E. Gudjonsson; Keith B. Elkon

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole-blood RNA transcriptome 通过全血RNA转录组整合分析实现抗磷脂综合征的分子分层

Arthritis & Rheumatology

IF10.9

2025-12-15

OAAI

Amala Ambati MD; Feiyang Ma PhD; Katarina Kmetova PhD; Sherwin Navaz BS; Claire K. Hoy BS; Cyrus Sarosh MSA; Ajay Tambralli MD; Erika Navarro-Mendoza MD; Johann E. Gudjonsson MD; J. Michelle Kahlenberg MD, PhD; Jacqueline A. Madison MD; Alí Duarte-García MD; Jason S. Knight MD, PhD; Yu Zuo MD, MS

A randomized phase 2 clinical trial to treat moderate-to-severe plaque psoriasis patients with high-induction dosing of risankizumab 一项随机第2期临床试验，旨在使用高诱导剂量risankizumab治疗中重度斑块状银屑病患者

Nature Communications

IF15.7

2025-12-11

OAAI

Andrew Blauvelt; Rundong Jiang; Linyu Shi; Lam C. Tsoi; Rachael Bogle; Jennifer Fox; Mehrnaz Gharaee-Kermani; Allison C. Billi; Robert T. Matheson; Huzefa Photowala; Johann E. Gudjonsson; Benjamin D. Ehst

TNF-α represses fibroblast to myofibroblast transition through the histone methyltransferase Setdb2 TNF-α通过组蛋白甲基转移酶Setdb2抑制成纤维细胞向肌成纤维细胞的转化。

JCI INSIGHT

IF6.1

2025-11-24

PREAI

Bauer, Tyler M.; Mangum, Kevin D.; Buckley, Samuel D.; Shadiow, James; Joshi, Amrita D.; Audu, Christopher O.; Moon, Jadie Y.; Hughes, Lindsey D.; Bogel, Rachel; Tsoi, Lam C.; Li, Qinmennge; Zhang, He; Kunkel, Steven; Gudjonsson, Johann E.; Davis, Frank M.; Gallagher, Katherine A.

研究方向