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M

Mrinal K. Sarkar

university of michigan
H指数:35
被引数:4,108

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Single-cell transcriptome reveals keratinocyte subclusters contributing to altered differentiation and inflammatory responses in atopic dermatitis

单细胞转录组揭示特应性皮炎中参与分化改变和炎症反应的角质形成细胞亚群

Nature Communications
IF15.7
2026-07-140
OAAI
Tingting Qin; Rachael Bogle; Rundong Jiang; Mrinal K. Sarkar; Yuli Cai; Mehrnaz Gharaee-Kermani; Jennifer Fox; Xianying Xing; Sahiti Marella; Mio Nakamura; Emanual Maverakis; Stephanie T. Le; Alexander A. Merleev; Alina I. Marusina; Cory L. Simpson; Arti Parihar; Connor Hill; He Li; J. Michelle Kahlenberg; Dawn M. Waterworth; Nina Sabins; Lloyd S. Miller; Tom C. Freeman; Monica WL Leung; Marta E. Polak; Lam C. Tsoi; Allison C. Billi; Johann E. Gudjonsson
Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis

以IL-36/TNFSF15反应为中心的动态中性粒细胞-角化细胞通讯网络，表征了泛发性脓疱型银屑病中的炎症反应。

Nature Communications
IF15.7
2025-12-230
OAAI
Rundong Jiang; Joseph Kirma; Jennifer Fox; Xianying Xing; Jiaqi Wang; Mrinal K. Sarkar; Rachael Bogle; Tran Do; Anthony Coon; Christopher Cole; Olesya Plazyo; Joanna E. Rew; Haihan Zhang; J. Michelle Kahlenberg; Allison C. Billi; Hervé Bachelez; Lam C. Tsoi; Paul W. Harms; Shuai Shao; Xiang Chen; Johann E. Gudjonsson
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes

包L，Guerrero-Juarez CF，李J，Pigors M，Emtenani S，刘Y，等. IgG自身抗体在疱疹样皮炎中诱导角蛋白细胞产生一种依赖MyD88的致病性促炎反应。Nat Commun. (2025) 16:7254. doi: 10.1038/s41467-025-62495-2

Nature Communications
IF15.7
2025-08-060
OAAI
Lei Bao; Christian F. Guerrero-Juarez; Jing Li; Manuela Pigors; Shirin Emtenani; Yingzi Liu; Adrian P. Mansini; Yulu F. Wang; Aadil Ahmed; Norito Ishii; Takashi Hashimoto; Bethany E. Perez White; Stefan Green; Kevin Kunstman; Nicole C. Nowak; Connor Cole; Mrinal K. Sarkar; Johann E. Gudjonsson; Macias Virgilia; Maria Sverdlov; M. Allen McAlexander; Christopher McCrae; Christopher D. Nazaroff; Enno Schmidt; Kyle T. Amber
Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier

花依赖性的层状体运输促进了表皮屏障的成熟

Nature Communications
IF15.7
2025-07-260
OAAI
Justin C. Rudd; Jos P. H. Smits; Patrick T. Kuwong; Rachel E. Johnson; Louise M. N. Monga; Ivonne M. J. J. van Vlijmen-Willems; Greer L. Porter; Peter O. Halloran; Kanika Sharma; Karina N. Schmidt; Vikas Kumar; Justin G. Madson; Mrinal K. Sarkar; Ellen H. van den Bogaard; James A. Grunkemeyer; Johann E. Gudjonsson; Sunny Y. Wong; Cory L. Simpson; Laura A. Hansen
Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis

整合全基因组关联研究、数量性状基因座和角质形成细胞功能实验揭示了特应性皮炎的分子机制

NATURE COMMUNICATIONS
IF15.7
2025-04-010
OA
Oliva, Meritxell; Sarkar, Mrinal K.; March, Michael E.; Saeidian, Amir Hossein; Mentch, Frank D.; Hsieh, Chen-Lin; Tang, Fanying; Uppala, Ranjitha; Patrick, Matthew T.; Li, Qinmengge; Bogle, Rachael; Kahlenberg, J. Michelle; Watson, Deborah; Glessner, Joseph T.; Youssefian, Leila; Vahidnezhad, Hassan; Tsoi, Lam C.; Gudjonsson, Johann E.; Smith, Kathleen M.; Riley-Gillis, Bridget
Characterizing the immune infiltrate in secondary syphilis: implications for transmission and pathology

表征二期梅毒的免疫浸润：对传播和病理学的意义

FRONTIERS IN IMMUNOLOGY
IF5.9
2025-03-250
OA
Serezal, Irene Gallais; Kirma, Joseph; Sarkar, Mrinal K.; Cole, Christopher; Xing, Xianying; Bogle, Rachael; Fox, Jennifer; Coon, Anthony; Vanstraalen, Kelsey R.; Dobry, Craig; Xu, Linda H.; Kahlenberg, J. Michelle; Harms, Paul W.; Billi, Allison C.; Tsoi, Lam C.; Giacani, Lorenzo; Gudjonsson, Johann E.
Targeting IL-1 controls refractory pityriasis rubra pilaris
SCIENCE ADVANCES
IF12.5
2024-07-051
OAAI
Schmauch, Eloi; Severin, Yannik; Xing, Xianying; Mangold, Aaron; Conrad, Curdin; Johannsen, Pal; Kahlenberg, J. Michelle; Mellett, Mark; Navarini, Alexander; Nobbe, Stefan; Sarkar, Mrinal K.; Satyam, Abhigyan; Tsoi, Lam C.; French, Lars E.; Nilsson, Jakob; Linna-Kuosmanen, Suvi; Kaikkonen, Minna U.; Snijder, Berend; Kellis, Manolis; Gudjonsson, Johann E.; Tsokos, George C.; Contassot, Emmanuel; Kolios, Antonios G. A.
Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling
JCI INSIGHT
IF6.1
2024-03-123
OAAI
Jiang, Yanyun; Gruszka, Dennis; Zeng, Chang; Swindell, William R.; Gaskill, Christa; Sorensen, Christian; Brown, Whitney; Gangwar, Roopesh Singh; Tsoi, Lam C.; Webster, Joshua; Siguroardottir, Sigrun Laufey; Sarkar, Mrinal K.; Uppala, Ranjitha; Kidder, Austin; Xing, Xianying; Plazyo, Olesya; Xing, Enze; Billi, Allison C.; Maverakis, Emanual; Kahlenberg, J. Michelle; Gudjonsson, Johann E.; Ward, Nicole L.
Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2024-03-016
PRE
Yu, Zizi; Vieyra-Garcia, Pablo; Benezeder, Theresa; Crouch, Jack D.; Kim, Ira R.; O'Malley, John T.; Devlin, Phillip M.; Gehad, Ahmed; Zhan, Qian; Gudjonsson, Johann E.; Sarkar, Mrinal K.; Kahlenberg, J. Michelle; Gerard, Nega; Teague, Jessica E.; Kupper, Thomas S.; Leboeuf, Nicole R.; Larocca, Cecilia; Tawa, Marianne; Pomahac, Bohdan; Talbot, Simon G.; Orgill, Dennis P.; Wolf, Peter; Clark, Rachael A.
Pansclerotic morphea is characterized by IFN-? responses priming dendritic cell fibroblast crosstalk to promote fibrosis
JCI INSIGHT
IF6.1
2023-08-226
OA
Xing, Enze; Ma, Feiyang; Wasikowski, Rachael; Billi, Allison C.; Gharaee-Kermani, Mehrnaz; Fox, Jennifer; Dobry, Craig; Victory, Amanda; Sarkar, Mrinal K.; Xing, Xianying; Plazyo, Olesya; Chen, Henry W.; Barber, Grant; Jacobe, Heidi; Tsou, Pei-Suen; Modlin, Robert L.; Varga, John; Kahlenberg, J. Michelle; Tsoi, Lam C.; Gudjonsson, Johann E.; Khanna, Dinesh
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
NATURE COMMUNICATIONS
IF15.7
2023-06-1264
OAAI
Ma, Feiyang; Plazyo, Olesya; Billi, Allison C. C.; Tsoi, Lam C. C.; Xing, Xianying; Wasikowski, Rachael; Gharaee-Kermani, Mehrnaz; Hile, Grace; Jiang, Yanyun; Harms, Paul W. W.; Xing, Enze; Kirma, Joseph; Xi, Jingyue; Hsu, Jer-En; Sarkar, Mrinal K. K.; Chung, Yutein; Di Domizio, Jeremy; Gilliet, Michel; Ward, Nicole L. L.; Maverakis, Emanual; Klechevsky, Eynav; Voorhees, John J. J.; Elder, James T. T.; Lee, Jun Hee; Kahlenberg, J. Michelle; Pellegrini, Matteo; Modlin, Robert L. L.; Gudjonsson, Johann E. E.

研究方向

暂未获取到该数据
J
Jóhann E. Guðjónsson
H 指数:80论文数:597被引数:2.6万
L
Lam C. Tsoi
H 指数:63论文数:414被引数:1.3万
X
Xianying Xing
H 指数:44论文数:163被引数:6,024
J
J. Michelle Kahlenberg
H 指数:50论文数:243被引数:8,447
J
John J. Voorhees
H 指数:112论文数:570被引数:4.6万
W
William R. Swindell
H 指数:49论文数:175被引数:9,061
P
Paul W. Harms
H 指数:52论文数:312被引数:9,259
R
Ranjitha Uppala
H 指数:17论文数:38被引数:1,835
A
Allison C. Billi
H 指数:33论文数:166被引数:4,150
Y
Yun Liang
H 指数:20论文数:89被引数:1,997