Barbara A. Konkle - Publications, H-index & Citations

Barbara A. Konkle

University of Pennsylvania

59H指数

392论文数

2.2W被引数

收录论文 115

发表时间

Prospective collection of bleeding rate and factor usage in participants with hemophilia A and B in a noninvestigational product study 在非研究性产品研究中对血友病A和B患者出血率和因子使用情况进行前瞻性收集

Research and Practice in Thrombosis and Haemostasis

IF3.4

2026-08-01

PREAI

Kavakli, Kaan; Frenzel, Laurent; Antmen, Ali Bulent; Alzahrani, Hazzaa; Matino, Davide; Leavitt, Andrew D.; Ozelo, Margareth C.; Astermark, Jan; Park, Young-Shil; Klamroth, Robert; Cuker, Adam; Konkle, Barbara A.; McKay, John; Agathon, Delphine; Tseng, Li-Jung; Resa, Maria de los Angeles; Healy, Jasmine; Wilcox, Lisa J.; Plonski, Frank

A Revised Classification of FVIII Concentrates: Rationale and Novel Metrics FVIII浓缩剂的修订分类：理论基础与新指标

Blood Advances

IF7.1

2026-02-16

OAAI

Cedric Hermans; Pratima Chowdary; Barbara A. Konkle; Johnny Mahlangu; Axel Facius; Maria Elisa Mancuso

Outcomes in participants switching from FVIII replacement therapy to efanesoctocog alfa prophylaxis in XTEND-1: a post hoc analysis XTEND-1从FVIII替代治疗转向efanesocog alfa预防的参与者的结果: 事后分析

Therapeutic Advances in Hematology

IF3.1

2026-01-20

PREAI

Sophie Susen; Roshni Kulkarni; Keiji Nogami; Flora Peyvandi; Barbara Konkle; Elena Santagostino; Umer Khan; Annemieke Willemze; Linda Bystrická; Jennifer Dumont; Pratima Chowdary

Early Detection of Post-Traumatic Heterotopic Ossification in Bleeding Disorders Using Ultrasound 使用超声对出血性疾病中创伤后异位骨化的早期检测

JOURNAL OF ULTRASOUND IN MEDICINE

IF2.4

2025-12-01

PREAI

Steiner, Bruno U. K.; Krimmel, Mark A.; Chang, Eric; Bryan, Cassandra; Timmer, Merel; Hernandez, Grace; Kallberg, Jeffrey; Khan, Osman; Schmaderer, Lorene; Loeffler, Fred; Akins, Stacie; Kaltenmark, Tiffany; Cave, Stacey; Ovans, Jessica; Konkle, Barbara; Kruse-Jarres, Rebecca

The WFH Guidelines for the Management of Haemophilia: AAV Gene Therapy, 2025 《WFH Guidelines for the Management of Haemophilia: AAV Gene Therapy, 2025》

Haemophilia

IF3

2025-10-25

OAAI

Glenn F. Pierce; Margareth C. Ozelo; Johnny Mahlangu; Amy L. Dunn; Marlene Beijlevelt; Rose Bender; Manuel Carcao; Donna Coffin; Enrico Ferri Grazzi; Graham R. Foster; Julie Frantsve-Hawley; Alfonso Iorio; Shannon Jackson; Radoslaw Kaczmarek; Gwendolyn E. Kaeser; Barbara A. Konkle; Magdalena Lewandowska; Wolfgang Miesbach; Brian O'Mahony; Steven Pipe; Ulrike M. Reiss; Amy K. Wilson; Emna Gouider; Miguel Escobar; the WFH AAV Gene Therapy Guidelines Expert Panel

Correction: A scan of pleiotropic immune mediated disease genes identifies novel determinants of baseline FVIII inhibitor status in hemophilia A 更正：对多效性免疫介导疾病基因的扫描识别出血友病A中基线FVIII抑制剂状态的新的决定因素

Genes & Immunity

IF0

2025-09-25

PREAI

Marcio A. Almeida; Vincent P. Diego; Kevin R. Viel; Bernadette W. Luu; Karin Haack; Raja Rajalingam; Afshin Ameri; Meera Chitlur; Natalia Rydz; David Lillicrap; Raymond G. Watts; Craig M. Kessler; Christopher Ramsey; Long V. Dinh; Benjamin Kim; Jerry S. Powell; Eron G. Manusov; Juan M. Peralta; Ruayda Bouls; Shirley M. Abraham; Yu-Min Shen; Carlos M. Murillo; Henry Mead; Paul V. Lehmann; Eli J. Fine; Miguel A. Escobar; Satish Kumar; Barbara A. Konkle; Sarah Williams-Blangero; Carol K. Kasper; Laura Almasy; Shelley A. Cole; John Blangero; Tom E. Howard

Exploration of biomarkers for inhibitor development in persons with hemophilia A 探索血友病A患者中抑制剂开发的生物标志物

Research and Practice in Thrombosis and Haemostasis

IF3.4

2025-05-01

OAAI

Meng-Ni Fan; Tangliang Shen; Barbara A. Konkle; Xiaohe Cai; Ting-Yen Chao; Marilyn Manco-Johnson; Anna V. Faino; Junping Zhang; Shumin Bao; Weidong Xiao; Lei Li; Carol H. Miao

A scan of pleiotropic immune mediated disease genes identifies novel determinants of baseline FVIII inhibitor status in hemophilia A 对多效性免疫介导疾病基因的扫描识别出血友病A中基础FVIII抑制剂状态的新的决定因素

GENES AND IMMUNITY

IF4.5

2025-04-22

PREAI

Almeida, Marcio A.; Diego, Vincent P.; Viel, Kevin R.; Luu, Bernadette W.; Haack, Karin; Raja, Rajalingam; Ameri, Afshin; Chitlur, Meera; Rydz, Natalia; Lillicrap, David; Watts, Raymond G.; Kessler, Craig M.; Ramsey, Christopher; Dinh, Long V.; Kim, Benjamin; Powell, Jerry S.; Manusov, Eron G.; Peralta, Juan M.; Bouls, Ruayda; Abraham, Shirley M.; Shen, Yu-Min; Murillo, Carlos M.; Mead, Henry; Lehmann, Paul V.; Fine, Eli J.; Escobar, Miguel A.; Kumar, Satish; Konkle, Barbara A.; Williams-Blangero, Sarah; Kasper, Carol K.; Almasy, Laura; Cole, Shelley A.; Blangero, John; Howard, Tom E.

Corticosteroid use to mitigate transaminitis-associated decline in FVIII levels following valoctocogene roxaparvovec gene therapy: clinical practice guidance 使用糖皮质激素以减轻valoctocogene roxaparvovec基因治疗后与转氨酶升高相关的FVIII水平下降：临床实践指南

Journal of Thrombosis and Haemostasis

IF5

2025-03-14

OAAI

Barbara A. Konkle; Flora Peyvandi; Graham R. Foster; Cedric Hermans; Vincenzo La Mura; Andrew D. Leavitt; David Lillicrap; Johnny Mahlangu; Margareth C. Ozelo; Steven Pipe; Michael Recht; Alok Srivastava; Guy Young; Wolfgang Miesbach

Rescue of the endogenous FVIII expression in hemophilia A mice using CRISPR-Cas9 mRNA LNPs

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-12-01

PREAI

Chen, Chun-Yu; Cai, Xiaohe; Konkle, Barbara A.; Miao, Carol H.

Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes

NATURE COMMUNICATIONS

IF15.7

2024-05-24

OAAI

Keener, Rebecca; Chhetri, Surya B.; Connelly, Carla J.; Taub, Margaret A.; Conomos, Matthew P.; Weinstock, Joshua; Ni, Bohan; Strober, Benjamin; Aslibekyan, Stella; Auer, Paul L.; Barwick, Lucas; Becker, Lewis C.; Blangero, John; Bleecker, Eugene R.; Brody, Jennifer A.; Cade, Brian E.; Celedon, Juan C.; Chang, Yi-Cheng; Cupples, L. Adrienne; Custer, Brian; Freedman, Barry I.; Gladwin, Mark T.; Heckbert, Susan R.; Hou, Lifang; Irvin, Marguerite R.; Isasi, Carmen R.; Johnsen, Jill M.; Kenny, Eimear E.; Kooperberg, Charles; Minster, Ryan L.; Naseri, Take; Viali, Satupa'itea; Nekhai, Sergei; Pankratz, Nathan; Peyser, Patricia A.; Taylor, Kent D.; Telen, Marilyn J.; Wu, Baojun; Yanek, Lisa R.; Yang, Ivana V.; Albert, Christine; Arnett, Donna K.; Ashley-Koch, Allison E.; Barnes, Kathleen C.; Bis, Joshua C.; Blackwell, Thomas W.; Boerwinkle, Eric; Burchard, Esteban G.; Carson, April P.; Chen, Zhanghua; Chen, Yii-Der Ida; Darbar, Dawood; de Andrade, Mariza; Ellinor, Patrick T.; Fornage, Myriam; Gelb, Bruce D.; Gilliland, Frank D.; He, Jiang; Islam, Talat; Kaab, Stefan; Kardia, Sharon L. R.; Kelly, Shannon; Konkle, Barbara A.; Kumar, Rajesh; Loos, Ruth J. F.; Martinez, Fernando D.; McGarvey, Stephen T.; Meyers, Deborah A.; Mitchell, Braxton D.; Montgomery, Courtney G.; North, Kari E.; Palmer, Nicholette D.; Peralta, Juan M.; Raby, Benjamin A.; Redline, Susan; Rich, Stephen S.; Roden, Dan; Rotter, Jerome I.; Ruczinski, Ingo; Schwartz, David; Sciurba, Frank; Shoemaker, M. Benjamin; Silverman, Edwin K.; Sinner, Moritz F.; Smith, Nicholas L.; Smith, Albert V.; Tiwari, Hemant K.; Vasan, Ramachandran S.; Weiss, Scott T.; Williams, L. Keoki; Zhang, Yingze; Ziv, Elad; Raffield, Laura M.; Reiner, Alexander P.; Arvanitis, Marios; Greider, Carol W.; Mathias, Rasika A.; Battle, Alexis

Recommendations for a minimum data set for monitoring gene therapy in hemophilia: communication from the ISTH SSC Working Group on Gene Therapy 关于监测血友病基因治疗的最小数据集的建议: ISTH SSC基因治疗工作组的交流

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2024-05-01

PREAI

Miesbach, Wolfgang; Konkle, Barbara; Chowdary, Pratima; Kaczmarek, Radoslaw; Leebeek, Frank; Mahlangu, Johnny; Makris, Michael; Pipe, Steven W.; Srivastava, Alok; Voorberg, Jan; Pierce, Glenn F.; Peyvandi, Flora

The importance and evolution of bleeding disorder registries 出血性疾病登记的重要性和演变

HAEMOPHILIA

IF3

2024-04-03

PREAI

Tran, Huyen; Yang, Renchi; Fischer, Kathelijn; Makris, Michael; Konkle, Barbara A.

Landmark endorsement of a global registry: The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP), publicly endorses World Federation of Hemophilia Gene Therapy Registry as global standard 具有里程碑意义的全球注册认可: 欧洲药品管理局 (EMA) 人用药品委员会 (CHMP) 公开认可世界血友病基因治疗注册联合会作为全球标准

HAEMOPHILIA

IF3

2023-12-18

PREAI

Konkle, Barbara A.; Peyvandi, Flora; Coffin, Donna; Naccache, Mayss; Youttananukorn, Toong; Pierce, Glenn F.

Dynamic and functional linkage between von Willebrand factor and ADAMTS-13 with aging: an Atherosclerosis Risk in Community study

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2023-12-01

PREAI

Liu, Wei; Patel, Kavita; Wang, Yi; Nodzenski, Michael; Nguyen, Ashley; Teramura, Gayle; Higgins, Harrison A.; Hoogeveen, Ron C.; Couper, David; Fu, Xiaoyun; Konkle, Barbara A.; Loop, Matthew Shane; Dong, Jing-fei

The World Federation of Hemophilia World Bleeding Disorders Registry: insights from the first 10,000 patients

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2023-11-01

OAAI

Coffin, Donna; Gouider, Emma; Konkle, Barbara; Hermans, Cedric; Lambert, Catherine; Diop, Saliou; Ayoub, Emily; Tootoonchian, Ellia; Youttananukorn, Toong; Dakik, Pamela; Pereira, Ticiana; Iorio, Alfonso; Pierce, Glenn F.

A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one-stage clotting and chromogenic substrate assays at clinical haemostasis laboratories 一项全球比较现场研究，通过临床止血实验室的一阶段凝血和生色底物测定法评估efanesocog α 的VIII因子活性

HAEMOPHILIA

IF3

2023-10-30

OAAI

Pipe, Steven; Sadeghi-Khomami, Ali; Konkle, Barbara A.; Kitchen, Steve; Negrier, Claude; Liu, Mingjie; Santagostino, Elena; Willemze, Annemieke; Abad-Franch, Lydia; Knobe, Karin; Seth Chhabra, Ekta

Prophylaxis with a recombinant factor VIII Fc in hemophilia A: long-term follow-up on joint health, efficacy, and safety from phase 3 studies in children and adults 重组因子VIII Fc预防血友病a: 儿童和成人3期研究关节健康、疗效和安全性的长期随访

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2023-08-01

OAAI

Konkle, Barbara A.; Oldenburg, Johannes; Pasi, John; Kulkarni, Roshni; Nolan, Beatrice; Mahlangu, Johnny; Young, Guy; Brown, Simon A.; Pabinger, Ingrid; Shapiro, Amy; Negrier, Claude; Blanchette, Victor; Ragni, Margaret, V; Dumont, Jennifer; Lethagen, Stefan

Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants mRNA剪接的遗传控制是稀有编码变体不完全外显率的潜在机制

GENETICS

IF5.1

2023-06-22

OAAI

Einson, Jonah; Glinos, Dafni; Boerwinkle, Eric; Castaldi, Peter; Darbar, Dawood; de Andrade, Mariza; Ellinor, Patrick; Fornage, Myriam; Gabriel, Stacey; Germer, Soren; Gibbs, Richard; Hersh, Craig P.; Johnsen, Jill; Kaplan, Robert; Konkle, Barbara A.; Kooperberg, Charles; Nassir, Rami; Loos, Ruth J. F.; Meyers, Deborah A.; Mitchell, Braxton D.; Psaty, Bruce; Vasan, Ramachandran S.; Rich, Stephen S.; Rienstra, Michael; Rotter, Jerome, I; Saferali, Aabida; Shoemaker, Moore Benjamin; Silverman, Edwin; Smith, Albert Vernon; Mohammadi, Pejman; Castel, Stephane E.; Iossifov, Ivan; Lappalainen, Tuuli

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes

SCIENCE ADVANCES

IF12.5

2023-04-28

OAAI

Weinstock, Joshua S.; Laurie, Cecelia A.; Broome, Jai G.; Taylor, Kent D.; Guo, Xiuqing; Shuldiner, Alan R.; O'Connell, Jeffrey R.; Lewis, Joshua P.; Boerwinkle, Eric; Barnes, Kathleen C.; Chami, Nathalie; Kenny, Eimear E.; Loos, Ruth J. F.; Fornage, Myriam; Redline, Susan; Cade, Brian E.; Gilliland, Frank D.; Chen, Zhanghua; Gauderman, W. James; Kumar, Rajesh; Grammer, Leslie; Schleimer, Robert P.; Psaty, Bruce M.; Bis, Joshua C.; Brody, Jennifer A.; Silverman, Edwin K.; Yun, Jeong H.; Qiao, Dandi; Weiss, Scott T.; Lasky-Su, Jessica; DeMeo, Dawn L.; Palmer, Nicholette D.; Freedman, Barry I.; Bowden, Donald W.; Cho, Michael H.; Vasan, Ramachandran S.; Johnson, Andrew D.; Yanek, Lisa R.; Becker, Lewis C.; Kardia, Sharon; He, Jiang; Kaplan, Robert; Heckbert, Susan R.; Smith, Nicholas L.; Wiggins, Kerri L.; Arnett, Donna K.; Irvin, Marguerite R.; Tiwari, Hemant; Correa, Adolfo; Raffield, Laura M.; Gao, Yan; de Andrade, Mariza; Rotter, Jerome I.; Rich, Stephen S.; Manichaikul, Ani W.; Konkle, Barbara A.; Johnsen, Jill M.; Wheeler, Marsha M.; Custer, Brian S.; Duggirala, Ravindranath; Curran, Joanne E.; Blangero, John; Gui, Hongsheng; Xiao, Shujie; Williams, L. Keoki; Meyers, Deborah A.; Li, Xingnan; Ortega, Victor; McGarvey, Stephen; Gu, C. Charles; Chen, Yii-Der Ida; Lee, Wen-Jane; Shoemaker, M. Benjamin; Darbar, Dawood; Roden, Dan; Albert, Christine; Kooperberg, Charles; Desai, Pinkal; Blackwell, Thomas W.; Abecasis, Goncalo R.; V. Smith, Albert; Kang, Hyun M.; Mathias, Rasika; Natarajan, Pradeep; Jaiswal, Siddhartha; Reiner, Alexander P.; Bick, Alexander G.

研究方向