J. Edwin Blalock - Publications, H-index & Citations

J. Edwin Blalock

university of alabama at birmingham

74H指数

419论文数

2.0W被引数

收录论文 84

发表时间

Electronic cigarette (E-Cigarette) vapor amplifies inflammation and the pathogenic extracellular vesicle signature associated with LPS-driven lung injury

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Madison, Matthew C.; Finley, Dakota C.; Smith, Julian B.; Noa, Aaron S.; Gaggar, Amit; Blalock, J. Edwin

E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS 电子烟烟雾放大了中性粒细胞性炎症和蛋白水解性外泌体对LPS的响应。

Frontiers in Immunology

IF5.9

2025-09-03

OAAI

Lawrence W. Rasmussen; Dakota C. Finley; Julian B. Smith; Aaron S. Noa; J. Edwin Blalock; Amit Gaggar; Matthew C. Madison

Pathogenic extracellular vesicles link smoking to COPD

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Margaroli, Camilla; Madison, Matthew C.; Genschmer, Kristopher R.; Russell, Derek W.; Wells, James M.; Sari, Ezgi; Soto-Vazquez, Yixel; Guo, Yuanyuan; Mincham, Kyle; Snelgrove, Robert J.; Gaggar, Amit; Blalock, James E.

Leukotriene A4 hydrolase (LTA4H) inside neutrophil derived extracellular vesicles breaks down PGP when exposed to neutrophil elastase

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Genschmer, Kristopher; Langster, Tamiajoi; Xu, Ningyong; Blalock, J. Edwin; Russell, Derek

A lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation

NATURE COMMUNICATIONS

IF15.7

2024-08-19

OAAI

Nicola, Teodora; Wenger, Nancy; Xu, Xin; Evans, Michael; Qiao, Luhua; Rezonzew, Gabriel; Yang, Youfeng; Jilling, Tamas; Margaroli, Camilla; Genschmer, Kristopher; Willis, Kent; Ambalavanan, Namasivayam; Blalock, J. Edwin; Gaggar, Amit; Lal, Charitharth Vivek

Airway extracellular LTA4H 4 H concentrations are governed by release from liver hepatocytes and changes in lung vascular permeability 气道细胞外LTA4H 4h浓度受肝肝细胞释放和肺血管通透性变化的控制

CELL REPORTS

IF6.9

2024-08-01

OAAI

Mincham, Kyle T.; Akthar, Samia; Patel, Dhiren F.; Meyer, Garance F.; Lloyd, Clare M.; Gaggar, Amit; Blalock, James E.; Snelgrove, Robert J.

Neutrophil elastase-dependent cleavage of LTA4H alters its aminopeptidase activity in cystic fibrosis

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-02-22

OAAI

Xu, Xi; Li, Jin-dong; Green, Todd J.; Wilson, Landon; Russell, Kristopher Genschmer Derek; Russell, Derek; Blalock, J. Edwin; Gaggar, Amit

Protease-armed, Pathogenic Extracellular Vesicles Link Smoking and Chronic Obstructive Pulmonary Disease

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2023-11-15

PREAI

Madison, Matthew C.; Margaroli, Camilla; Genschmer, Kristopher R.; Russell, Derek W.; Wells, James M.; Sari, Ezgi; Soto-Vazquez, Yixel M.; Guo, Yuan-Yuan; Mincham, Kyle T.; Snelgrove, Robert J.; Gaggar, Amit; Blalock, James E.

The matrikine Ac-PGP mediates the pathogenesis of pulmonary hypertension

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Xu, Xin; Roda, Mojtaba Abdul; Xing, Dongqi; Li, Jindong; Mcnicholas-Bevensee, Carmel; Payne, Gregory A.; Viera, Liliana; Patel, Rakesh; Wells, J. Michael; Folkerts, Gert; Blalock, J. Edwin; Gaggar, Amit

Therapeutic effect of two strategies directed at disruption of pathogenic neutrophil extracellular vesicles in a murine emphysema model 两种针对小鼠肺气肿模型中致病性中性粒细胞细胞外囊泡破坏的策略的治疗作用

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2023-05-01

OAAI

Genschmer, Kristopher R.; Madison, Matthew; Viera, Liliana; Margaroli, Camilla; Gaggar, Amit; Blalock, J. Edwin; Russell, Derek W.

Extracellular Vesicles as Central Mediators of COPD Pathophysiology

ANNUAL REVIEW OF PHYSIOLOGY

IF19.1

2022-02-10

OAAI

Russell, Derek W.; Genschmer, Kristopher R.; Blalock, J. Edwin

An in vivo model for extracellular vesicle- induced emphysema

JCI INSIGHT

IF6.1

2022-01-25

OAAI

Margaroli, Camilla; Madison, Matthew C.; Viera, Liliana; Russell, Derek W.; Gaggar, Amit; Genschmer, Kristopher R.; Blalock, J. Edwin

A mechanism for matrikine regulation in acute inflammatory lung injury 急性炎症肺损伤中基质因子调节的机制

JCI INSIGHT

IF6.1

2021-04-08

OAAI

Robison, Sarah W.; Li, JinDong; Viera, Liliana; Blackburn, Jonathan P.; Patel, Rakesh P.; Blalock, J. Edwin; Gaggar, Amit; Xu, Xin

Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection

JCI INSIGHT

IF6.1

2021-03-22

OAAI

Payne, Gregory A.; Sharma, Nirmal S.; Lal, Charitharth, V; Song, Chunyan; Guo, Lingling; Margaroli, Camilla; Viera, Liliana; Kumar, Siva; Li, Jindong; Xing, Dongqi; Bosley, Melanie; Xu, Xin; Wells, J. Michael; George, James F.; Tallaj, Jose; Leesar, Massoud; Blalock, J. Edwin; Gaggar, Amit

Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-01-04

OAAI

Benjamin, John T.; Plosa, Erin J.; Sucre, Jennifer M. S.; van der Meer, Riet; Dave, Shivangi; Gutor, Sergey; Nichols, David S.; Gulleman, Peter M.; Jetter, Christopher S.; Han, Wei; Xin, Matthew; Dinella, Peter C.; Catanzarite, Ashley; Kook, Seunghyi; Dolma, Kalsang; Lal, Charitharth V.; Gaggar, Amit; Blalock, J. Edwin; Newcomb, Dawn C.; Richmond, Bradley W.; Kropski, Jonathan A.; Young, Lisa R.; Guttentag, Susan H.; Blackwell, Timothy S.

Comment on: Pathological consequences of Anti-Citrullinated Protein Antibodies in Tear Fluid and therapeutic potential of Pooled Human Immune Globulin-Eye Drops in Dry Eye Disease: Too much of a good thing, how chronic neutrophilic inflammation can drive human disease

OCULAR SURFACE

IF5.6

2020-04-01

PREAI

Genschmer, Kristopher R.; Russel, Derek W.; Blalock, J. Edwin

Effects of hyperoxia on alveolar and pulmonary vascular development in germ-free mice

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2020-02-01

OAAI

Dolma, Kalsang; Freeman, Amelia E.; Rezonzew, Gabriel; Payne, Gregory A.; Xu, Xin; Jilling, Tamas; Blalock, J. Edwin; Gaggar, Amit; Ambalavanan, Namasivayam; Lal, Charitharth Vivek

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis

JOURNAL OF CYSTIC FIBROSIS

IF6

2020-01-01

OAAI

Turnbull, Andrew R.; Pyle, Chloe J.; Patel, Dhiren F.; Jackson, Patricia L.; Hilliard, Tom N.; Regamey, Nicolas; Tan, Hui-Leng; Brown, Sarah; Thursfield, Rebecca; Short, Christopher; Mc Fie, Megan; Alton, Eric W. F. W.; Gaggar, Amit; Blalock, J. Edwin; Lloyd, Clare M.; Bush, Andrew; Dayies, Jane C.; Snelgrove, Robert J.

Attacking the NE plus exosome with protamine sulfate effectively attenuates ECM remodeling in a COPD mouse model

EUROPEAN RESPIRATORY JOURNAL

IF21

2019-11-21

PREAI

Russell, Derek W.; Genschmer, Kristopher R.; Wells, J. Michael; Gaggar, Amit; Blalock, J. Edwin

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

DEVELOPMENTAL CELL

IF8.7

2019-11-01

OAAI

Cui, Guiying; Hong, Jeong; Chung-Davidson, Yu-Wen; Infield, Daniel; Xu, Xin; Li, Jindong; Simhaev, Luba; Khazanov, Netaly; Stauffer, Brandon; Imhoff, Barry; Cottrill, Kirsten; Blalock, J. Edwin; Li, Weiming; Senderowitz, Hanoch; Sorscher, Eric; McCarty, Nael A.; Gaggar, Amit

研究方向