John K. Cowell - Publications, H-index & Citations

John K. Cowell

georgia cancer center

67H指数

503论文数

1.5W被引数

收录论文 137

发表时间

A gene signature derived from leukemia associated macrophages provides a compelling risk stratification for human AML patients 来自白血病相关巨噬细胞的基因签名为人类AML患者提供了令人信服的风险分层

Biomarker Research

IF11.5

2026-05-29

OAAI

Deedra Nicolet; Ting Zhang; Christopher J. Walker; Justice Ameyi; Stephanie F. Mori; Xuexiu Fang; Litao Zhang; Jorge Cortes; Catherine C. Hedrick; John K. Cowell; Ann-Kathrin Eisfeld; Tianxiang Hu

Genomic Analysis Defines Increased Circulating, Leukemia-Induced Macrophages That Promote Immune Suppression in Mouse Models of FGFR1-Driven Leukemogenesis 基因组分析定义了在FGFR1驱动的白血病发生小鼠模型中，循环性白血病诱导巨噬细胞的增加，这些细胞促进免疫抑制。

Cells 2025, Vol. 14, Page 1533

IF5.2

2025-09-30

OAAI

Ting Zhang; Atsuko Matsunaga; Xiaocui Lu; Hui Fang; Nandini Chatterjee; Ahmad Alimadadi; Stephanie F. Mori; Xuexiu Fang; Gavin Wang; Huidong Shi; Litao Zhang; Catherine C. Hedrick; Bo Cheng; Tianxiang Hu; John K. Cowell

Reducing the wait for dementia diagnosis: another use for day hospitals

AGE AND AGEING

IF7.1

2025-01-30

PREAI

Keir, S.; Mcclung, I; Smith, L.; Cowell, J.

Single-cell analysis defines highly specific leukemia-induced neutrophils and links MMP8 expression to recruitment of tumor associated neutrophils during FGFR1 driven leukemogenesis

hematology oncology

IF13.5

2024-05-10

OAAI

Hu, Tianxiang; Cheng, Bo; Matsunaga, Atsuko; Zhang, Ting; Lu, Xiaocui; Fang, Hui; Mori, Stephanie F.; Fang, Xuexiu; Wang, Gavin; Xu, Hongyan; Shi, Huidong; Cowell, John K.

Macrophage instead of leukemia cell expressed PD-L1 drives T cell exhaustion and immune evasion of BCRABL1 chronic myeloid leukemia

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lu, Xiaocui; Fang, Hui; Fang, Xuexiu; Matsunaga, Atsuko; Liu, Kebin; Cortes, Jorge; Cowell, John K.; Hu, Tianxiang

Identification of small molecules that suppress cell invasion and metastasis promoted by WASF3 activation

HELIYON

IF3.6

2023-10-01

OAAI

Silva, Jeane; Omar, Nivin; Sittaramane, Vinoth; Cowell, John K.

IRAK1 regulated inflammatory signal from the leukemia cells modulates tumor microenvironment and promote leukemogenesis

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Zhang, Ting; Lu, Xiaocui; Matsunaga, Atsuko; Fang, Xuexiu; Mori, Stephanie Fay; Cowell, John; Hu, Tianxiang

CD71 and CD117 identifies an early cancer associated macrophage progenitor population in leukemic mouse bone marrow

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Lu, Xiaocui; Zhang, Ting; Matsunaga, Atsuko; Fang, Xuexiu; Mori, Stephanie F.; Cowell, John; Hu, Tianxiang

Targeting the WASF3 complex to suppress metastasis

PHARMACOLOGICAL RESEARCH

IF10.5

2022-08-01

OAAI

Limaye, Ameya J.; Whittaker, Matthew K.; Bendzunas, George N.; Cowell, John K.; Kennedy, Eileen J.

A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML

MOLECULAR CANCER

IF33.9

2022-07-29

OAAI

Cai, Baohuan; Liu, Yun; Chong, Yating; Mori, Stephanie Fay; Matsunaga, Atsuko; Zhang, Hualei; Fang, Xuexiu; Chang, Chang-Sheng; Cowell, John K.; Hu, Tianxiang

RHOA-regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia

HAEMATOLOGICA

IF7.9

2022-07-14

OAAI

Zhang, Hualei; Cai, Baohuan; Liu, Yun; Chong, Yating; Matsunaga, Atsuko; Mori, Stephanie Fay; Fang, Xuexiu; Kitamura, Eiko; Chang, Chang-Sheng; Wang, Ping; Cowell, John K.; Hu, Tianxiang

IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies

MOLECULAR CANCER

IF33.9

2021-12-14

OAAI

Cai, Baohuan; Liu, Yun; Chong, Yating; Zhang, Hualei; Matsunaga, Atsuko; Fang, Xuexiu; Pacholczyk, Rafal; Zhou, Gang; Cowell, John K.; Hu, Tianxiang

Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome

CELL DEATH & DISEASE

IF9.6

2020-10-20

OAAI

Liu, Yun; Cai, Baohuan; Chong, Yating; Zhang, Hualei; Kemp, Chesley-Anne; Lu, Sumin; Chang, Chang-Sheng; Ren, Mingqiang; Cowell, John K.; Hu, Tianxiang

Inactivation of Lgi1 in murine neuronal precursor cells leads to dysregulation of axon guidance pathways

GENOMICS

IF3

2020-03-01

PREAI

Silva, Jeane; Hawthorn, Lesleyann; Cowell, John K.

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

GENOMICS

IF3

2019-12-01

OAAI

Silva, Jeane; Chang, Chang-Sheng; Hu, Tianxiang; Qin, Haiyan; Kitamura, Eiko; Hawthorn, Lesleyann; Ren, Mingqiang; Cowell, John K.

DNA methyltransferase 1?mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1?driven leukemogenesis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-01

OAAI

Hu, Tianxiang; Chong, Yating; Cai, Baohuan; Liu, Yun; Lu, Sumin; Cowell, John

Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2019-10-10

OAAI

Chong, Yating; Liu, Yun; Lu, Sumin; Cai, Baohuan; Qin, Haiyan; Chang, Chang-Sheng; Ren, Mingqiang; Cowell, John K.; Hu, Tianxiang

Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome

HAEMATOLOGICA

IF7.9

2019-06-20

OAAI

Hu, Tianxiang; Chong, Yating; Lu, Sumin; McGuinness, Meaghan; Williams, David A.; Cowell, John K.

The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20 (vol 38, pg 469, 2018)

ONCOGENE

IF7.3

2019-06-13

OAAI

Lee, Eunmi; Ouzounova, Maria; Piranlioglu, Raziye; Minh Thu Ma; Guzel, Mustafa; Marasco, Daniela; Chadli, Ahmed; Gestwicki, Jason E.; Cowell, John K.; Wicha, Max S.; Hassan, Khaled A.; Korkaya, Hasan

The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-04-01

OAAI

Eisa, Nada H.; Jilani, Yasmeen; Kainth, Kashish; Redd, Priscilla; Lu, Su; Bougrine, Oulia; Sater, Houssein Abdul; Patwardhan, Chaitanya A.; Shull, Austin; Shi, Huidong; Liu, Kebin; Elsherbiny, Nehal M.; Eissa, Laila A.; El-Shishtawy, Mamdouh M.; Horuzsko, Anatolij; Bollag, Roni; Maihle, Nita; Roig, Joan; Korkaya, Hasan; Cowell, John K.; Chadli, Ahmed

研究方向