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S

Stephen H. Leppla

national institutes of health (nih) - usa

H指数:89

被引数:2.3万

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Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody

双链RNA被J2单克隆抗体识别的结构基础

Nature Communications

IF15.7

2025-12-130

OAAI

Environmental regulation of toxin production in Bacillus anthracis

炭疽芽孢杆菌毒素生产的环境调控

IF4.9

2025-12-011

PRE

Anthrax ET activates Rac1 and RTK signaling to induce F-actin reorganization and endothelial permeability

炭疽ET通过激活Rac1和RTK信号通路来诱导F-actin重组和血管内皮通透性。

IF4.1

2025-10-030

OAAI

Targeting virulence to disarm the pathogen: Enzyme-activated-substrate inhibition of Anthrax edema factor

靶向毒力以解除病原体武装：酶激活底物抑制炭疽水肿因子

Bioorganic & Medicinal Chemistry Letters

IF2.2

2025-09-020

PRE

ERK pathway reactivation prevents anthrax toxin lethality in mice

ERK通路再激活可防止炭疽毒素在小鼠中的致死性。

NATURE MICROBIOLOGY

IF19.4

2025-03-281

PRE

Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system

IF4.7

2024-12-110

OAAI

Environmental Regulation of Toxin Production in Bacillus Anthracis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-010

OAAI

S9.6-based hybrid capture immunoassay for pathogen detection

SCIENTIFIC REPORTS

IF3.9

2023-12-191

OAAI

S9.6 Antibody-Enzyme Conjugates for the Detection of DNA-RNA Hybrids

BIOCONJUGATE CHEMISTRY

IF3.9

2023-04-175

OAAI

Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27159

OAAI

Dph3, a small protein required for diphthamide biosynthesis, is essential in mouse development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2765

OAAI

ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth

宿主来源的肿瘤内皮细胞中的ERK和c-myc信号传导对实体瘤生长至关重要

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-2716

OAAI

Role of serine/threonine protein phosphatase PrpN in the life cycle of Bacillus anthracis

IF4.9

2022-08-013

OAAI

Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-083

OAAI

A potent tumor-selective ERK pathway inactivator with high therapeutic index

IF3.8

2022-07-015

OAAI

Structural basis of R-loop recognition by the S9.6 monoclonal antibody

NATURE COMMUNICATIONS

IF15.7

2022-03-2841

OAAI

Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-01-014

OAAI

The Crystal Structure of Bacillus cereus HblL1

IF4

2021-03-317

OAAI

A Review of the Efficacy of FDA-Approved B. anthracis Anti-Toxin Agents When Combined with Antibiotic or Hemodynamic Support in Infection- or Toxin-Challenged Preclinical Models

IF4

2021-01-132

OAAI

Inhibitory Effects of a Reengineered Anthrax Toxin on Canine and Human Osteosarcoma Cells

IF4

2020-09-241

OAAI