Nicholas Topley - Publications, H-index & Citations

Nicholas Topley

Cardiff University School of Medicine

69H指数

255论文数

1.5W被引数

收录论文 79

发表时间

The Role of Peritoneal IL-6 in Predicting Patient Survival on PD 腹膜IL-6在预测PD患者生存中的作用

Kidney International Reports

IF5.7

2025-07-03

OAAI

Emma H. Elphick; Vasileios Zavvos; John Belcher; Nicholas Topley; James A. Chess; Clifford J. Holmes; Simon J. Davies; Donald Fraser; Mark Lambie

Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements

JOURNAL OF IMMUNOLOGY

IF3.4

2023-06-05

OAAI

Millrine, David; Figueras, Ana Cardus; Fernandez, Javier Uceda; Andrews, Robert; Szomolay, Barbara; Cossins, Benjamin C.; Rice, Christopher M.; Li, Jasmine; Tyrrell, Victoria J.; McLeod, Louise; Holmans, Peter; O'Donnell, Valerie B.; Taylor, Philip R.; Turner, Stephen J.; Jenkins, Brendan J.; Jones, Gareth W.; Topley, Nicholas; Williams, Nigel M.; Jones, Simon A.

Measurement of innate immune response biomarkers in peritoneal dialysis effluent using a rapid diagnostic point-of-care device as a diagnostic indicator of peritonitis

KIDNEY INTERNATIONAL

IF12.6

2020-06-01

OAAI

Goodlad, Catriona; George, Sophiamma; Sandoval, Shella; Mepham, Stephen; Parekh, Gita; Eberl, Matthias; Topley, Nicholas; Davenport, Andrew

Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms

SCIENTIFIC REPORTS

IF3.9

2019-12-23

OAAI

Gadalla, Amal A. H.; Friberg, Ida M.; Kift-Morgan, Ann; Zhang, Jingjing; Eberl, Matthias; Topley, Nicholas; Weeks, Ian; Cuff, Simone; Wootton, Mandy; Gal, Micaela; Parekh, Gita; Davis, Paul; Gregory, Clive; Hood, Kerenza; Hughes, Kathryn; Butler, Christopher; Francis, Nick A.

Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients

FRONTIERS IN PHYSIOLOGY

IF3.4

2019-02-18

OAAI

Yu, Zanzhe; Lambie, Mark; Chess, James; Williams, Andrew; Do, Jun-Young; Topley, Nicholas; Davies, Simon J.

Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IF7.1

2018-08-31

OAAI

Elphick, Emma H.; Teece, Lucy; Chess, James A.; Do, Jun-Young; Kim, Yong-Lim; Lee, H. Bahl; Davison, Sara N.; Topley, Nicholas; Davies, Simon J.; Lambie, Mark

Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis

KIDNEY INTERNATIONAL

IF12.6

2018-08-01

PREAI

Raby, Anne-Catherine; Gonzalez-Mateo, Guadalupe T.; Williams, Aled; Topley, Nicholas; Fraser, Donald; Lopez-Cabrera, Manuel; Labeta, Mario O.

Fetuin-A in the peritoneal effluent of patients with encapsulating peritoneal sclerosis-more than a protein? Reply

KIDNEY INTERNATIONAL

IF12.6

2017-11-01

OAAI

Zavvos, Vasileios; Davies, Simon J.; Topley, Nicholas; Johnson, Timothy S.

Biomarker research to improve clinical outcomes of peritoneal dialysis: consensus of the European Training and Research in Peritoneal Dialysis (EuTRiPD) network

KIDNEY INTERNATIONAL

IF12.6

2017-10-01

OAAI

Aufricht, Christoph; Beelen, Robert; Eberl, Matthias; Fischbach, Michel; Fraser, Donald; Joerres, Achim; Kratochwill, Klaus; LopezCabrera, Manuel; Rutherford, Peter; Schmitt, Claus-Peter; Topley, Nicholas; Witowski, Janusz

A prospective, proteomics study identified potential biomarkers of encapsulating peritoneal sclerosis in peritoneal effluent 一项前瞻性蛋白质组学研究确定了腹膜流出物中包裹腹膜硬化的潜在生物标志物

KIDNEY INTERNATIONAL

IF12.6

2017-10-01

OAAI

Zavvos, Vasileios; Buxton, Anthony T.; Evans, Caroline; Lambie, Mark; Davies, Simon J.; Topley, Nicholas; Wilkie, Martin; Summers, Angela; Brenchley, Paul; Goumenos, Dimitrios S.; Johnson, Timothy S.

Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections

KIDNEY INTERNATIONAL

IF12.6

2017-07-01

OAAI

Zhang, Jingjing; Friberg, Ida M.; Kift-Morgan, Ann; Parekh, Gita; Morgan, Matt P.; Liuzzi, Anna Rita; Lin, Chan-Yu; Donovan, Kieron L.; Colmont, Chantal S.; Morgan, Peter H.; Davis, Paul; Weeks, Ian; Fraser, Donald J.; Topley, Nicholas; Eberl, Matthias

Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes 腹膜巨噬细胞异质性与不同腹膜透析结局相关

KIDNEY INTERNATIONAL

IF12.6

2017-05-01

OAAI

Liao, Chia-Te; Andrews, Robert; Wallace, Leah E.; Khan, Mohd Wajid A.; Kift-Morgan, Ann; Topley, Nicholas; Fraser, Donald J.; Taylor, Philip R.

Unconventional Human T Cells Accumulate at the Site of Infection in Response to Microbial Ligands and Induce Local Tissue Remodeling

JOURNAL OF IMMUNOLOGY

IF3.4

2016-09-15

OAAI

Liuzzi, Anna Rita; Kift-Morgan, Ann; Lopez-Anton, Melisa; Friberg, Ida M.; Zhang, Jingjing; Brook, Amy C.; Roberts, Gareth W.; Donovan, Kieron L.; Colmont, Chantal S.; Toleman, Mark A.; Bowen, Timothy; Johnson, David W.; Topley, Nicholas; Moser, Bernhard; Fraser, Donald J.; Eberl, Matthias

Implication of IL-7 in mesothelial paracellular resistance, migration and interaction with colorectal cancer cells

EUROPEAN JOURNAL OF CANCER

IF7.1

2015-09-01

PREAI

Sanders, A.; Owen, S.; Topley, N.; Kift-Morgan, A.; Jiang, W.

The biological and in vivo impact of Yangzheng Xiaoji extract on the interaction between tumour and peritoneal mesothelial cells and peritoneal metastases of gastrointestinal tumours

EUROPEAN JOURNAL OF CANCER

IF7.1

2015-09-01

PREAI

Ji, K.; Jia, Y.; Gao, Y.; Wei, C.; Wu, Y.; Topley, N.; Kift-Morgan, A.; Ji, J.; Jiang, W. G.

Pathogen-specific immune fingerprints during acute infection: the diagnostic potential of human γδ T-cells

FRONTIERS IN IMMUNOLOGY

IF5.9

2014-11-13

OAAI

Eberl, Matthias; Friberg, Ida M.; Liuzzi, Anna Rita; Morgan, Matt P.; Topley, Nicholas

Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation Interleukin-6信号在未解决的炎症中驱动纤维化

IMMUNITY

IF26.3

2014-01-01

304

OAAI

Fielding, Ceri A.; Jones, Gareth W.; McLoughlin, Rachel M.; McLeod, Louise; Hammond, Victoria J.; Uceda, Javier; Williams, Anwen S.; Lambie, Mark; Foster, Thomas L.; Liao, Chia-Te; Rice, Christopher M.; Greenhill, Claire J.; Colmont, Chantal S.; Hams, Emily; Coles, Barbara; Kift-Morgan, Ann; Newton, Zarabeth; Craig, Katherine J.; Williams, John D.; Williams, Geraint T.; Davies, Simon J.; Humphreys, Ian R.; O'Donnell, Valerie B.; Taylor, Philip R.; Jenkins, Brendan J.; Topley, Nicholas; Jones, Simon A.

Innate neutrophil function is regulated locally through IL-6 control of prostaglandins

CYTOKINE

IF3.7

2013-09-01

PREAI

Rice, Christopher M.; Greenhill, Claire J.; Jones, Gareth W.; Aldrovandi, Maceler; Hammond, Victoria J.; O'Donnell, Valerie B.; Topley, Nicholas; Taylor, Philip R.; Jones, Simon A.

IL-6 regulation of Th1 responses drives fibrosis in unresolved inflammation

CYTOKINE

IF3.7

2013-09-01

PREAI

Fielding, Ceri A.; Jones, Gareth W.; Taylor, Philip R.; Jenkins, Brendan J.; Topley, Nicholas; Jones, Simon A.

Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2013-05-15

PREAI

Raby, Anne-Catherine; Holst, Benjamin; Le Bouder, Emmanuel; Diaz, Constantino; Ferran, Edgardo; Conraux, Laurence; Guillemot, Jean-Claude; Coles, Barbara; Kift-Morgan, Ann; Colmont, Chantal S.; Szakmany, Tamas; Ferrara, Pascual; Hall, Judith E.; Topley, Nicholas; Labeta, Mario O.

研究方向