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S

Shuan Rao

Nanfang Hospital
H指数:31
被引数:1.1万

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Targeting DDX3X suppresses progression of KRAS-driven lung cancer by disrupting antioxidative homeostasis and inducing ferroptosis

靶向DDX3X通过破坏抗氧化稳态并诱导铁死亡，抑制了KRAS驱动的肺癌进展。

Cell Death & Disease
IF9.6
2025-08-300
OAAI
Meijuan Dian; Liang Yun; Qingyu Meng; Songwen Lin; Ming Ji; Ying Zhou; Wenqian Liu; Zhuoying Yang; Yayan Zhao; Gaoyuan Li; Jianjun Jiang; Weichao Hao; Zhijie Chen; Zehao Zhou; Ruihao Zhang; Tianyuan Liu; Yujing He; Tianbao Yan; Haofei Wang; Shane J. F. Cronin; Josef M. Penninger; Kaican Cai; Shuan Rao
Author Correction: SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming

作者更正：SHP-1抑制靶向白血病干细胞，通过代谢重编程恢复免疫监视并增强化疗敏感性

Nature Cell Biology
IF19.1
2025-08-110
OAAI
Xi Xu; Yanhui Yu; Wenwen Zhang; Weiwei Ma; Chong He; Guo Qiu; Xinyi Wang; Qiong Liu; Minyi Zhao; Jiayi Xie; Fang Tao; John M. Perry; Qifa Liu; Shuan Rao; Xunlei Kang; Meng Zhao; Linjia Jiang
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-08-3120
OA
Cronin, Shane J. F.; Rao, Shuan; Tejada, Miguel A.; Turnes, Bruna Lenfers; Licht-Mayer, Simon; Omura, Takao; Brenneis, Christian; Jacobs, Emily; Barrett, Lee; Latremoliere, Alban; Andrews, Nick; Channon, Keith M.; Latini, Alexandra; Arvanites, Anthony C.; Davidow, Lance S.; Costigan, Michael; Rubin, Lee L.; Penninger, Josef M.; Woolf, Clifford J.
EMERGE: A phase II trial assessing the efficacy of domatinostat plus avelumab in patients with previously treated advanced mismatch repair proficient oesophagogastric and colorectal cancers - phase IIA dose finding
ANNALS OF ONCOLOGY
IF65.4
2021-09-015
OAAI
Cartwright, E.; Turkes, F.; Saffery, C.; Tran, A.; Smith, G.; Moreno, S. Esteban; Hatt, S.; Renn, A.; Johnston, E.; Kohoutova, D.; Begum, R.; Smyth, E.; Peckitt, C.; Fribbens, C.; Rao, S.; Watkins, D.; Chau, I.; Starling, N.; Cunningham, D.
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases
CANCER RESEARCH
IF16.6
2020-07-1522
OAAI
Kogler, Melanie; Tortola, Luigi; Negri, Gian Luca; Leopoldi, Alexandra; El-Naggar, Amal M.; Mereiter, Stefan; Gomez-Diaz, Carlos; Nitsch, Roberto; Tortora, Davide; Kavirayani, Anoop M.; Gapp, Bianca, V; Rao, Shuan; Uribesalgo, Iris; Hoffmann, David; Cikes, Domagoj; Novatchkova, Maria; Williams, David A.; Trent, Jeffrey M.; Ikeda, Fumiyo; Daugaard, Mads; Hagelkruys, Astrid; Sorensen, Poul H.; Penninger, Josef M.

研究方向

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J
Josef Penninger
H 指数:174论文数:1,635被引数:14.3万
D
David Cunningham
H 指数:153论文数:2,060被引数:13.0万
I
Ian Chau
H 指数:81论文数:850被引数:4.4万
N
Naureen Starling
H 指数:43论文数:403被引数:1.3万
L
Luigi Tortola
H 指数:22论文数:67被引数:2,525
D
David Watkins
H 指数:33论文数:182被引数:5,431
I
Iris Uribesalgo
H 指数:19论文数:28被引数:2,325
G
Guido Kroemer
H 指数:283论文数:2,335被引数:36.9万
G
Gerald Wirnsberger
H 指数:24论文数:48被引数:5,776
I
I. Kozieradzki
H 指数:36论文数:129被引数:9,949