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G

Gerald Wirnsberger

Berlin Institute of Health
H指数:24
被引数:5,776

个人简介

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教育背景

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工作经历

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荣誉奖项

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Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level(Dec, 10.1038/s41467-022-35641-3,2022)
NATURE COMMUNICATIONS
IF15.7
2023-02-280
OAAI
Zhu, Rong; Canena, Daniel; Sikora, Mateusz; Klausberger, Miriam; Seferovic, Hannah; Mehdipour, Ahmad Reza; Hain, Lisa; Laurent, Elisabeth; Monteil, Vanessa; Wirnsberger, Gerald; Wieneke, Ralph; Tampe, Robert; Kienzl, Nikolaus F.; Mach, Lukas; Mirazimi, Ali; Oh, Yoo Jin; Penninger, Josef M.; Hummer, Gerhard; Hinterdorfer, Peter
FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder

FIBCD1是一种与新型神经发育障碍相关的内吞GAG受体

EMBO MOLECULAR MEDICINE
IF8.3
2022-08-028
OAAI
Fell, Christopher W.; Hagelkruys, Astrid; Cicvaric, Ana; Horrer, Marion; Liu, Lucy; Li, Joshua Shing Shun; Stadlmann, Johannes; Polyansky, Anton A.; Mereiter, Stefan; Tejada, Miguel Angel; Kokotovic, Tomislav; Achuta, Venkat Swaroop; Scaramuzza, Angelica; Twyman, Kimberly A.; Morrow, Michelle M.; Juusola, Jane; Yan, Huifang; Wang, Jingmin; Burmeister, Margit; Choudhury, Biswa; Andersen, Thomas Levin; Wirnsberger, Gerald; Holmskov, Uffe; Perrimon, Norbert; Zagrovic, Bojan; Monje, Francisco J.; Moeller, Jesper Bonnet; Penninger, Josef M.; Nagy, Vanja
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants

临床级ACE2作为阻断SARS-CoV-2变异的通用药物

EMBO MOLECULAR MEDICINE
IF8.3
2022-07-0435
OAAI
Monteil, Vanessa; Eaton, Brett; Postnikova, Elena; Murphy, Michael; Braunsfeld, Benedict; Crozier, Ian; Kricek, Franz; Niederhofer, Janine; Schwarzbock, Alice; Breid, Helene; Devignot, Stephanie; Klingstrom, Jonas; Thalin, Charlotte; Kellner, Max J.; Christ, Wanda; Havervall, Sebastian; Mereiter, Stefan; Knapp, Sylvia; Jimenez, Anna Sanchez; Bugajska-Schretter, Agnes; Dohnal, Alexander; Ruf, Christine; Gugenberger, Romana; Hagelkruys, Astrid; Montserrat, Nuria; Kozieradzki, Ivona; Ali, Omar Hasan; Stadlmann, Johannes; Holbrook, Michael R.; Schmaljohn, Connie; Oostenbrink, Chris; Shoemaker, Robert H.; Mirazimi, Ali; Wirnsberger, Gerald; Penninger, Josef M.
Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor

结构引导的ACE2糖工程可提高作为可溶性SARS-CoV-2诱饵受体的效力

ELIFE
IF0
2021-12-2027
PRE
Capraz, Tuemay; Kienzl, Nikolaus F.; Laurent, Elisabeth; Perthold, Jan W.; Foederl-Hoebenreich, Esther; Gruenwald-Gruber, Clemens; Maresch, Daniel; Monteil, Vanessa; Niederhofer, Janine; Wirnsberger, Gerald; Mirazimi, Ali; Zatloukal, Kurt; Mach, Lukas; Penninger, Josef M.; Oostenbrink, Chris; Stadlmann, Johannes
Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites

凝集素受体保守SARS-CoV-2糖基化位点的鉴定

EMBO JOURNAL
IF8.3
2021-08-2351
OAAI
Hoffmann, David; Mereiter, Stefan; Oh, Yoo Jin; Monteil, Vanessa; Elder, Elizabeth; Zhu, Rong; Canena, Daniel; Hain, Lisa; Laurent, Elisabeth; Gruenwald-Gruber, Clemens; Klausberger, Miriam; Jonsson, Gustav; Kellner, Max J.; Novatchkova, Maria; Ticevic, Melita; Chabloz, Antoine; Wirnsberger, Gerald; Hagelkruys, Astrid; Altmann, Friedrich; Mach, Lukas; Stadlmann, Johannes; Oostenbrink, Chris; Mirazimi, Ali; Hinterdorfer, Peter; Penninger, Josef M.
Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana

糖工程烟草中酶能SARS-CoV-2诱饵受体ACE2-Fc的产生

BIOTECHNOLOGY JOURNAL
IF3.1
2021-02-1225
OAAI
Castilho, Alexandra; Schwestka, Jennifer; Kienzl, Nikolaus F.; Vavra, Ulrike; Gruenwald-Gruber, Clemens; Izadi, Shiva; Hiremath, Chaitra; Niederhoefer, Janine; Laurent, Elisabeth; Monteil, Vanessa; Mirazimi, Ali; Wirnsberger, Gerald; Stadlmann, Johannes; Stoeger, Eva; Mach, Lukas; Strasser, Richard
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2020-09-1517
OAAI
Hagelkruys, Astrid; Wirnsberger, Gerald; Stadlmann, Johannes; Wohner, Miriam; Horrer, Marion; Vilagos, Bojan; Jonsson, Gustav; Kogler, Melanie; Tortola, Luigi; Novatchkova, Maria; Bonelt, Peter; Hoffmann, David; Koglgruber, Rubina; Steffen, Ulrike; Schett, Georg; Busslinger, Meinrad; Bergthaler, Andreas; Klein, Christoph; Penninger, Josef M.
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate (vol 15, pg 1481, 2016)
CELL REPORTS
IF6.9
2016-09-0116
OAAI
Tortola, Luigi; Nitsch, Roberto; Bertrand, Mathieu J. M.; Kogler, Melanie; Redouane, Younes; Kozieradzki, Ivona; Uribesalgo, Iris; Fennell, Lilian M.; Daugaard, Mads; Klug, Helene; Wirnsberger, Gerald; Wimmer, Reiner; Perlot, Thomas; Sarao, Renu; Rao, Shuan; Hanada, Toshikatsu; Takahashi, Nozomi; Kernbauer, Elisabeth; Demiroz, Duygu; Lang, Michaela; Superti-Furga, Giulio; Decker, Thomas; Pichler, Andrea; Ikeda, Fumiyo; Kroemer, Guido; Vandenabeele, Peter; Sorensen, Poul H.; Penninger, Josef M.
Inhibition of CBLB protects from lethal Candida albicans sepsis

抑制CBLB对致死性白色念珠菌败血症的保护作用

NATURE MEDICINE
IF50
2016-07-1898
OAAI
Wirnsberger, Gerald; Zwolanek, Florian; Asaoka, Tomoko; Kozieradzki, Ivona; Tortola, Luigi; Wimmer, Reiner A.; Kavirayani, Anoop; Fresser, Friedrich; Baier, Gottfried; Langdon, Wallace Y.; Ikeda, Fumiyo; Kuchler, Karl; Penninger, Josef M.
RANKL/RANK control Brca1 mutation-driven mammary tumors

RANKL/RANK控制Brca1突变驱动的乳腺肿瘤

CELL RESEARCH
IF25.9
2016-05-31127
OAAI
Sigl, Verena; Owusu-Boaitey, Kwadwo; Joshi, Purna A.; Kavirayani, Anoop; Wirnsberger, Gerald; Novatchkova, Maria; Kozieradzki, Ivona; Schramek, Daniel; Edokobi, Nnamdi; Hersl, Jerome; Sampson, Aishia; Odai-Afotey, Ashley; Lazaro, Conxi; Gonzalez-Suarez, Eva; Pujana, Miguel A.; Heyn, Holger; Vidal, Enrique; Cruickshank, Jennifer; Berman, Hal; Sarao, Renu; Ticevic, Melita; Uribesalgo, Iris; Tortola, Luigi; Rao, Shuan; Tan, Yen; Pfeiler, Georg; Lee, Eva Y. H. P.; Bago-Horvath, Zsuzsanna; Kenner, Lukas; Popper, Helmuth; Singer, Christian; Khokha, Rama; Jones, Laundette P.; Penninger, Josef M.
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate
CELL REPORTS
IF6.9
2016-05-0142
OAAI
Tortola, Luigi; Nitsch, Roberto; Bertrand, Mathieu J. M.; Kogler, Melanie; Redouane, Younes; Kozieradzki, Ivona; Uribesalgo, Iris; Fennell, Lilian M.; Daugaard, Mads; Klug, Helene; Wirnsberger, Gerald; Wimmer, Reiner; Perlot, Thomas; Sarao, Renu; Rao, Shuan; Hanada, Toshikatsu; Takahashi, Nozomi; Kernbauer, Elisabeth; Demiroez, Duygu; Superti-Furga, Giulio; Decker, Thomas; Pichler, Andrea; Ikeda, Fumiyo; Kroemer, Guido; Vandenabeele, Peter; Sorensen, Poul H.; Penninger, Josef M.
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense

Jagunal同源物1是真菌宿主防御中嗜中性粒细胞功能的关键调节剂

NATURE GENETICS
IF31.8
2014-09-0155
OAAI
Wirnsberger, Gerald; Zwolanek, Florian; Stadlmann, Johannes; Tortola, Luigi; Liu, Shang Wan; Perlot, Thomas; Jaervinen, Paeivi; Duenberger, Gerhard; Kozieradzki, Ivona; Sarao, Renu; De Martino, Alba; Boztug, Kaan; Mechtler, Karl; Kuchler, Karl; Klein, Christoph; Elling, Ulrich; Penninger, Josef M.
A dual role for autophagy in a murine model of lung cancer

自噬在小鼠肺癌模型中的双重作用

NATURE COMMUNICATIONS
IF15.7
2014-01-20390
OA
Rao, Shuan; Tortola, Luigi; Perlot, Thomas; Wirnsberger, Gerald; Novatchkova, Maria; Nitsch, Roberto; Sykacek, Peter; Frank, Lukas; Schramek, Daniel; Komnenovic, Vukoslav; Sigl, Verena; Aumayr, Karin; Schmauss, Gerald; Fellner, Nicole; Handschuh, Stephan; Gloesmann, Martin; Pasierbek, Pawel; Schlederer, Michaela; Resch, Guenter P.; Ma, Yuting; Yang, Heng; Popper, Helmuth; Kenner, Lukas; Kroemer, Guido; Penninger, Josef M.
Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

通过衍生单倍体小鼠胚胎干细胞的正向和反向遗传学

CELL STEM CELL
IF20.4
2011-12-01243
OA
Elling, Ulrich; Taubenschmid, Jasmin; Wirnsberger, Gerald; O'Malley, Ronan; Demers, Simon-Pierre; Vanhaelen, Quentin; Shukalyuk, Andrey I.; Schmauss, Gerald; Schramek, Daniel; Schnuetgen, Frank; von Melchner, Harald; Ecker, Joseph R.; Stanford, William L.; Zuber, Johannes; Stark, Alexander; Penninger, Josef M.

研究方向

暂未获取到该数据
J
Josef Penninger
H 指数:174论文数:1,635被引数:14.3万
L
Luigi Tortola
H 指数:22论文数:67被引数:2,525
V
Vanessa Monteil
H 指数:23论文数:61被引数:5,814
J
Johannes Stadlmann
H 指数:46论文数:100被引数:6,935
I
I. Kozieradzki
H 指数:36论文数:129被引数:9,949
A
Alì Mirazimi
H 指数:57论文数:321被引数:1.2万
E
Elisabeth Laurent
H 指数:15论文数:40被引数:534
S
Shuan Rao
H 指数:31论文数:139被引数:1.1万
L
Lukas Mach
H 指数:44论文数:121被引数:5,970
A
Astrid Hagelkrüys
H 指数:22论文数:62被引数:4,004