Philip N. Tsichlis - Publications, H-index & Citations

Philip N. Tsichlis

University System of Ohio

76H指数

316论文数

2.6W被引数

收录论文 119

发表时间

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4 在ncPRC1.1的背景下并与MYC和ATF4协同作用下，KDM2B对氨基酸代谢的转录调控

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2024-01-01

OAAI

Chavdoula, Evangelia; Anastas, Vollter; La Ferlita, Alessandro; Aldana, Julian; Carota, Giuseppe; Spampinato, Mariarita; Soysal, Burak; Cosentini, Ilaria; Parashar, Sameer; Sircar, Anuvrat; Nigita, Giovanni; Sehgal, Lalit; Freitas, Michael A.; Tsichlis, Philip N.

Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia 人内源性逆转录病毒在慢性淋巴细胞白血病中的表达特征

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-23

OAAI

La Ferlita, Alessandro; Nigita, Giovanni; Tsyba, Liudmyla; Palamarchuk, Alexey; Alaimo, Salvatore; Pulvirenti, Alfredo; Balatti, Veronica; Rassenti, Laura; Tsichlis, Philip N.; Kipps, Thomas; Pekarsky, Yuri; Croce, Carlo M.

Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma

LEUKEMIA

IF13.4

2023-08-19

OAAI

Sircar, Anuvrat; Singh, Satishkumar; Xu-Monette, Zijun Y.; Coyle, Krysta Mila; Hilton, Laura K.; Chavdoula, Evangelia; Ranganathan, Parvathi; Jain, Neeraj; Hanel, Walter; Tsichlis, Philip; Alinari, Lapo; Peterson, Blake R.; Tao, Jianguo; Muthusamy, Natarajan; Baiocchi, Robert; Epperla, Narendranath; Young, Ken H.; Morin, Ryan; Sehgal, Lalit

The Akt-IWS1 signaling axis regulates microRNA activity

CANCER RESEARCH

IF16.6

2023-04-14

PREAI

Christodoulou, Niki; Hatziapostolou, Maria; Montiel-Duarte, Cristina; Edwards, Elisabetta Verderio; Tsichlis, Philip N.; Polytarchou, Christos

KDM2B regulates Serine-Glycine-One Carbon (SGOC) metabolism by targeting the SGOC enzyme genes via a combination of direct and indirect epigenetic mechanisms

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Chavdoula, Evangelia; Anastas, Vollter; La Ferlita, Allesandro; Aldana, Julian; Carota, Giuseppe; Spampinato, Mariarita; Parashar, Sameer; Cosentini, Ilaria; Soysal, Burak; Nigita, Giovanni; Freitas, Michael; Tsichlis, Philip

Phosphatidylinositol 3-kinase is required for integlrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

417

OAAI

King, WG; Mattaliano, MD; Chan, TO; Tsichlis, PN; Brugge, JS

The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

125

OAAI

Tong, B; Grimes, HL; Yang, TY; Bear, SE; Qin, ZH; Du, KY; El-Deiry, WS; Tsichlis, PN

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

193

OAAI

Eves, EM; Xiong, W; Bellacosa, A; Kennedy, SG; Tsichlis, PN; Rosner, MR; Hay, N

The JmjC Domain Histone Demethylase Ndy1 Regulates Redox Homeostasis and Protects Cells from Oxidative Stress

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Polytarchou, Christos; Pfau, Raymond; Hatziapostolou, Maria; Tsichlis, Philip N.

Phophorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Robinson, M. J.; Beinke, S.; Kouroumalis, A.; Tsichlis, P. N.; Ley, S. C.

Stat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Schmidt, Jeffrey W.; Wehde, Barbara L.; Sakamoto, Kazuhito; Triplett, Aleata A.; Anderson, Steven M.; Tsichlis, Philip N.; Leone, Gustavo; Wagner, Kay-Uwe

Small cell lung cancer: Subtypes and therapeutic implications

SEMINARS IN CANCER BIOLOGY

IF15.7

2022-11-01

PREAI

Wang, Walter Z.; Shulman, Alyssa; Amann, Joseph M.; Carbone, David P.; Tsichlis, Philip N.

Akt isoforms in the immune system

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-08-23

OAAI

Guerau-de-Arellano, Mireia; Piedra-Quintero, Zayda L. L.; Tsichlis, Philip N.

The Role of AKT in Soft Tissue Sarcoma: Review and Insights

MOLECULAR CANCER RESEARCH

IF4.7

2022-07-07

PREAI

Wang, Yu; Ilyas, Farhan Z.; Kheradmandi, Mahsa; Tsilimigras, Diamantis I.; Grignol, Valerie P.; Contreras, Carlo; Tsichlis, Philip N.; Pollock, Raphael E.; Beane, Joal D.

RETRACTION: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing (Retraction of Vol 12, art no 4624, 2021)

NATURE COMMUNICATIONS

IF15.7

2022-06-28

OAAI

Laliotis, Georgios I.; Chavdoula, Evangelia; Paraskevopoulou, Maria D.; Kaba, Abdul; La Ferlita, Alessandro; Singh, Satishkumar; Anastas, Vollter; Nair, Keith A., II; Orlacchio, Arturo; Taraslia, Vasiliki; Vlachos, Ioannis; Capece, Marina; Hatzigeorgiou, Artemis; Palmieri, Dario; Tsatsanis, Christos; Alaimo, Salvatore; Sehgal, Lalit; Carbone, David P.; Coppola, Vincenzo; Tsichlis, Philip N.

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology

CELL AND BIOSCIENCE

IF6.2

2022-05-07

OAAI

Tsimberidou, Apostolia-Maria; Skliris, Antonis; Valentine, Alan; Shaw, Jamie; Hering, Ursula; Vo, Henry Hiep; Chan, Tung On; Armen, Roger S.; Cottrell, Jeffrey R.; Pan, Jen Q.; Tsichlis, Philip N.

RETRACTION: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection (Retraction of Vol 4, art no 1179, 2021)

COMMUNICATIONS BIOLOGY

IF5.1

2021-12-15

OAAI

Laliotis, Georgios I.; Kenney, Adam D.; Chavdoula, Evangelia; Orlacchio, Arturo; Kaba, Abdul; La Ferlita, Alessandro; Anastas, Vollter; Tsatsanis, Christos; Beane, Joal D.; Sehgal, Lalit; Coppola, Vincenzo; Yount, Jacob S.; Tsichlis, Philip N.

RETRACTED: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection (Retracted Article)

COMMUNICATIONS BIOLOGY

IF5.1

2021-10-11

OAAI

RETRACTED: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing (Retracted article. See vol. 13, 2022)

NATURE COMMUNICATIONS

IF15.7

2021-07-30

OAAI

Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47phox

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-02

OAAI

Polytarchou, Christos; Hatziapostolou, Maria; Yau, Tung On; Christodoulou, Niki; Hinds, Philip W.; Kottakis, Filippos; Sanidas, Ioannis; Tsichlis, Philip N.

研究方向