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I

Ioannis Sanidas

Massachusetts General Hospital and Harvard Medical School
H指数:17
被引数:1,473

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Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth; Nordern, Bryanna; Chevalier, Nicholas; Leshchiner, Ignaty; Stavridi, Anastasia; Kim, Janice; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg; Bardia, Aditya; Spring, Laura; Isakoff, Steven; Lennerz, Jochen; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan; Juric, Dejan
Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway
CANCER RESEARCH
IF16.6
2024-04-050
PRE
de la Cruz, Ferran Fece; Varkaris, Andreas; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Patel, Parasvi; Kim, Janice S.; Ellis, Haley; Sanidas, Ioannis; Lau, Kayao T.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

变构PI3Kα 抑制克服了继发性PIK3CA突变介导的对正构抑制剂的靶向抗性

CANCER DISCOVERY
IF33.3
2023-10-3114
OAAI
Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Stavridi, Anastasia-Maria; Yuan, Xin; Kim, Janice S.; Ellis, Haley; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian P.; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg M.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Del Vecchio, Kathryn; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan
PTEN loss mediates clinical cross-resistance to CDK4/6 and PI3Ka inhibitors in breast cancer
CANCER RESEARCH
IF16.6
2020-08-151
PRE
Costa, Carlotta; Wang, Ye; Ly, Amy; Hosono, Yasuyuki; Murchie, Ellen; Walmsley, Charlotte S.; Huynh, Tiffany; Healy, Christopher; Peterson, Rachel; Yanase, Shogo; Jakubik, Charles T.; Henderson, Laura E.; Damon, Leah J.; Timonina, Daria; Sanidas, Ioannis; Pinto, Christopher J.; Mino-Kenudson, Mari; Stone, James; Dyson, Nicholas J.; Ellisen, Leif W.; Bardia, Aditya; Ebi, Hiromichi; Benes, Cyril H.; Engelman, Jeffrey A.; Juric, Dejan
PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer

PTEN缺失介导乳腺癌对CDK4/6和PI3Kα 抑制剂的临床交叉耐药

CANCER DISCOVERY
IF33.3
2020-01-09176
OAAI
Costa, Carlotta; Wang, Ye; Ly, Amy; Hosono, Yasuyuki; Murchie, Ellen; Walmsley, Charlotte S.; Huynh, Tiffany; Healy, Christopher; Peterson, Rachel; Yanase, Shogo; Jakubik, Charles T.; Henderson, Laura E.; Damon, Leah J.; Timonina, Daria; Sanidas, Ioannis; Pinto, Christopher J.; Mino-Kenudson, Mari; Stone, James R.; Dyson, Nicholas J.; Ellisen, Leif W.; Bardia, Aditya; Ebi, Hiromichi; Benes, Cyril H.; Engelman, Jeffrey A.; Juric, Dejan
IWS1 is essential for mouse development
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Orlacchio, Arturo; Foray, Claudia; Sheetz, Tyler; Reese, Erika; Amari, Foued; Stark, Aaron E.; La Perle, Krista; Sanidas, Ioannis; Tsichlis, Philip N.; Palmieri, Dario; Coppola, Vincenzo

研究方向

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N
Nicholas J. Dyson
H 指数:82论文数:263被引数:2.9万
P
Philip N. Tsichlis
H 指数:76论文数:316被引数:2.5万
F
Filippos Kottakis
H 指数:16论文数:83被引数:1,983
D
Dejan Juric
H 指数:59论文数:732被引数:2.0万
M
Michael S. Lawrence
H 指数:145论文数:649被引数:18.9万
A
Aditya Bardia
H 指数:86论文数:1,148被引数:3.8万
H
Hanjun Lee
H 指数:4论文数:19被引数:86
C
Christos Polytarchou
H 指数:36论文数:127被引数:4,872
S
Scott A. Ezell
H 指数:11论文数:50被引数:752
M
Maria Hatziapostolou
H 指数:30论文数:97被引数:4,738