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收藏On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy
Adhikari, Pragya; Li, Guangmin; Go, Maryann; Mandikian, Danielle; Rafidi, Hanine; Ng, Carl; Anifa, Sagana; Johnson, Kevin; Bao, Linda; Barry, Hilda Hernandez; Rowntree, Rebecca; Agard, Nicholas; Wu, Cong; Chou, Kang-Jye; Zhang, Donglu; Kozak, Katherine R.; Pillow, Thomas H.; Lewis, Gail D.; Yu, Shang-Fan; Boswell, C. Andrew; Sadowsky, Jack D. 分享 收藏 分享 收藏 The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial resultsLewis, Gail D.; Li, Guangmin; Guo, Jun; Yu, Shang-Fan; Fields, Carter T.; Lee, Genee; Zhang, Donglu; Dragovich, Peter S.; Pillow, Thomas; Wei, Binqing; Sadowsky, Jack; Leipold, Douglas; Wilson, Tim; Kamath, Amrita; Mamounas, Michael; Lee, M. Violet; Saad, Ola; Choeurng, Voleak; Ungewickell, Alexander; Monemi, Sharareh; Crocker, Lisa; Kalinsky, Kevin; Modi, Shanu; Jung, Kyung Hae; Hamilton, Erika; LoRusso, Patricia; Krop, Ian; Schutten, Melissa M.; Commerford, Renee; Sliwkowski, Mark X.; Cho, Eunpi 分享 收藏 Chiral quantum dots for bioapplicationsLi, Guangmin; Zheng, Jiayun; Li, Jiafeng; Kang, Jiajia; Jin, Xinyu; Guo, Anning; Chen, Zhibo; Fei, Xuening; Wang, Kaiyuan; Liu, Hongfei; Zhao, Hongbin; Liu, Wei; Yang, Gaoling 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Preclinical development of DHES0815A: A HER2-directed antibody-drug conjugate comprised of a reduced potency PBD dimer linked to a domain I binding HER2 antibodyPhillips, Gail Lewis; Li, Guangmin; Guo, Jun; Yu, Shang-Fan; Lee, Genee; Zhang, Donglu; Dragovich, Peter; Pillow, Thomas; Wei, Binqing; Lee, M. Violet; Saad, Ola; Masih, Shab; Leipold, Douglas; Crocker, Lisa; Schutten, Melissa 分享 收藏 分享 收藏 A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptidesZacharias, Neelie; Podust, Vladimir N.; Kajihara, Kimberly K.; Leipold, Douglas; Del Rosario, Geoffrey; Thayer, Desiree; Dong, Emily; Paluch, Maciej; Fischer, David; Zheng, Kai; Lei, Corinna; He, Jintang; Ng, Carl; Su, Dian; Liu, Luna; Masih, Shabkhaiz; Sawyer, William; Tinianow, Jeff; Marik, Jan; Yip, Victor; Li, Guangmin; Chuh, Josefa; Morisaki, J. Hiroshi; Park, Summer; Zheng, Bing; Hernandez-Barry, Hilda; Loyet, Kelly M.; Xu, Min; Kozak, Katherine R.; Phillips, Gail Lewis; Shen, Ben-Quan; Wu, Cong; Xu, Keyang; Yu, Shang-Fan; Kamath, Amrita; Rowntree, Rebecca K.; Reilly, Dorothea; Pillow, Thomas; Polson, Andrew; Schellenberger, Volker; Hazenbos, Wouter L. W.; Sadowsky, Jack 分享 收藏 Construction of a High-Performance Three-Dimensional Structured NiCo2O4@PPy Nanosheet Array Free-Standing Electrode for a Hybrid Supercapacitor用于混合超级电容器的高性能三维结构NiCo2O4 @ PPy纳米片阵列独立式电极的构建Yu, Jia; Yao, Di; Wu, Zongdeng; Li, Guangmin; Song, Juanjuan; Shen, Honglong; Yang, Xiaoqiang; Lei, Wu; Wu, Fengqin; Hao, Qingli 分享 收藏 Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug ConjugatesStaben, Leanna R.; Chen, Jinhua; dela Cruz-Chuh, Josefa; del Rosario, Geoff; Go, Mary Ann; Guo, Jun; Khojasteh, S. Cyrus; Kozak, Katherine R.; Li, Guangmin; Ng, Carl; Phillips, Gail D. Lewis; Pillow, Thomas H.; Rowntree, Rebecca K.; Wai, John; Wei, BinQing; Xu, Keyang; Xu, Zijin; Yu, Shang-Fan; Zhang, Donglu; Dragovich, Peter S. 分享 收藏 分享 收藏 Manganese doped Co3O4 mesoporous nanoneedle array for long cycle-stable supercapacitorsLi, Guangmin; Chen, Mingzhi; Ouyang, Yu; Yao, Di; Li, Lei; Wang, Liang; Xia, Xifeng; Lei, Wu; Chen, Shen-Ming; Mandler, Daniel; Hao, Qingli 分享 收藏 Hierarchical electrodes of NiCo2S4 nanosheets-anchored sulfur-doped Co3O4 nanoneedles with advanced performance for battery-supercapacitor hybrid devicesOuyang, Yu; Ye, Haitao; Xia, Xifeng; Jiao, Xinyan; Li, Guangmin; Mutahir, Sadaf; Wang, Liang; Mandler, Daniel; Lei, Wu; Hao, Qingli 分享 收藏 Development, Optimization, and Structural Characterization of an Efficient Peptide-Based Photoaffinity Cross-Linking Reaction for Generation of Homogeneous Conjugates from Wild-Type AntibodiesVance, Nicholas; Zacharias, Neelie; Ultsch, Mark; Li, Guangmin; Fourie, Aimee; Liu, Peter; LaFrance-Vanasse, Julien; Ernst, James A.; Sandoval, Wendy; Kozak, Katherine R.; Phillips, Gail; Wang, Weiru; Sadowsky, Jack 分享 收藏 分享 收藏 Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease SpecificityWei, BinQing; Gunzner-Toste, Janet; Yao, Hui; Wang, Tao; Wang, Jing; Xu, Zijin; Chen, Jinhua; Wai, John; Nonomiya, Jim; Tsai, Siao Ping; Chuh, Josefa; Kozak, Katherine R.; Liu, Yichin; Yu, Shang-Fan; Lau, Jeff; Li, Guangmin; Phillips, Gail D.; Leipold, Doug; Kamath, Amrita; Su, Dian; Xu, Keyang; Eigenbrot, Charles; Steinbacher, Stefan; Ohri, Rachana; Raab, Helga; Staben, Leanna R.; Zhao, Guiling; Flygare, John A.; Pillow, Thomas H.; Verma, Vishal; Masterson, Luke A.; Howard, Philip W.; Safina, Brian 分享 收藏 Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-LinkersGregson, Stephen J.; Masterson, Luke A.; Wei, Binqing; Pillow, Thomas H.; Spencer, Susan D.; Kang, Gyoung-Dong; Yu, Shang -Fan; Raab, Helga; Lau, Jeffrey; Li, Guangmin; Phillips, Gail D. Lewis; Gunner-Toste, Janet; Safina, Brian S.; Ohri, Rachana; Darwish, Martine; Kozak, Katherine R.; dela Cruz-Chuh, Josefa; Poison, Andrew; Flygare, John A.; Howard, Philip W. 分享 收藏 
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