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H

Hiroaki Wakimoto

harvard medical school

71H指数
642论文数
2.0W被引数
收录论文 185
发表时间
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Multimodal artificial intelligence integrating peritumoral MRI and clinical data stratifies meningioma recurrence risk after radiotherapy整合肿瘤周边MRI和临床数据的多模态人工智能对放疗后脑膜瘤复发风险进行分层
errnpj Digital Medicine
IF15.1
err2026-09-07
err0
errOAAI
errLeihao Ren; Jiaojiao Deng; Tianqi Wu; Renhua Huang; Jian Xu; Wei Huang; Jinxiu Yu; Louman Chan; Xuyang Yin; Yang Wang; Qing Xie; Hiroaki Wakimoto; Ye Gong; Hailiang Tang; Chunxia Ni; Lingyang Hua
err分享
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Acquired genetic and cell-state changes in IDH-mutant glioma progressionIDH突变型胶质瘤进展中的获得性遗传和细胞状态变化
errNature
IF48.5
err2026-06-03
err0
errOAAI
errKevin C. Johnson; Avishay Spitzer; Frederick S. Varn; Masashi Nomura; Luciano Garofano; Tamrin Chowdhury; Anuja Lipsa; Linbin Zhang; Ester Calvo Fernández; Tanyeri Barak; A. Gulhan Ercan-Sencicek; Ayse Buket Peksen; Kevin J. Anderson; C. Mircea S. Tesileanu; Samirkumar B. Amin; Emre Kocakavuk; Dacheng Zhao; Fulvio D’Angelo; Simona Migliozzi; Lillian Bussema; Simon Gritsch; Hyo-Eun Moon; Sun Ha Paek; Franck Bielle; Alice Laurenge; Anna Luisa Di Stefano; Bertrand Mathon; Alberto Picca; Marc Sanson; Ann-Christin Hau; Frank Hertel; Kamil Grzyb; Zheng Zhao; Qianghu Wang; Tao Jiang; Julie J. Miller; Hiroaki Wakimoto; Daniel P. Cahill; Jennifer Moliterno; Murat Günel; Beth Hermes; Nader Sanai; Anna Golebiewska; Simone P. Niclou; Jason Huse; W. K. Alfred Yung; Anna Lasorella; Mario L. Suvà; Antonio Iavarone; Itay Tirosh; Roel G. W. Verhaak
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A blueprint for local and distal invasion programs in glioblastoma胶质母细胞瘤局部和远处侵袭程序的蓝图
errNature Communications
IF15.7
err2026-03-17
err0
errOAAI
errRony Chanoch-Myers; Toshiro Hara; Alissa C. Greenwald; Rouven Hoefflin; Lillian Bussema; Hannah R. Weisman; Edwin Nieblas-Bedolla; Jahnavi Gurramkonda; Zhibek Bekezhankyzy; Alexander Jucht; Ester Calvo Fernández; Avishay Spitzer; Jeremy Man Hon Fung; Biella Chiara; Wajd N. Al-Holou; Sandra Camelo-Piragua; Jinan Behnan; Rossella Galli; Hiroaki Wakimoto; Mario L. Suvà; Itay Tirosh
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Effects of Short- and Long-Term Mutant IDH1 Inhibition on Radiosensitivity Across Genetically Diverse Patient-derived IDH1-Mutant Glioma Cells短期和长期突变IDH1抑制对基因异质性患者源性IDH1突变胶质瘤细胞放射敏感性的影响
errNeuro-Oncology Advances
IF4.1
err2026-03-02
err0
errOAAI
errYosuke Kitagawa; Logan D Muzyka; Ami Kobayashi; Ethan Wetzel; Ali Nasser; Julie J Miller; Hiroaki Wakimoto; Daniel P Cahill
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Long-term administration of the mutant IDH inhibitor DS-1001b suppresses the growth of IDH1-mutant glioma in vitro and in mouse xenograft models and alters epigenetic profiles长期给予突变型IDH抑制剂DS-1001b可抑制IDH1突变型胶质瘤在体外的生长及在小鼠异种移植模型中的生长，并改变表观遗传谱。
errActa Neuropathologica
IF9.3
err2026-02-12
err0
PREAI
errKenji Fujimoto; Mai Honda-Kitahara; Naoko Hattori; Yuko Matsushita; Yuko Hibiya; Kaishi Satomi; Hironori Matsunaga; Shinji Tsutsumi; Atsushi Okamoto; Tatsuya Inoue; Makiko Yamada; Makoto Watanabe; Hiroaki Wakimoto; Ritsuko Onuki; Mamoru Kato; Taka-Aki Sato; Toshikazu Ushijima; Issay Kitabayashi; Koichi Ichimura
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A nanobody-stem cell platform targeting innate and adaptive immune axis in the tumour microenvironment
erreBioMedicine
IF10.8
err2026-01-17
err0
errOAAI
errIoulia Vogiatzi; Amelia Lehmann; Chuang Liu; Lucia Moreno-Lama; Yoshinori Kajiwara; Nobuhiko Kanaya; Olivier Zwaenepoel; Ali Salehi Farid; Uk-Jae Lee; Filippo Rossignoli; Mohammad Rashidian; Hiroaki Wakimoto; Jan Gettemans; Khalid Shah
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Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cellsIDH1-R132H的棕榈酰化自调节其在癌细胞中的新生物活性
errNature Chemical Biology
IF13.7
err2026-01-13
err0
PREAI
errLu Hu; Jinyu Lin; Liping Sun; Alison M. Berezuk; Katharine S. Tuttle; Xing Zhu; Hyuk-Soo Seo; Sirano Dhe-Paganon; Pan Li; Yang Sun; Lisheng Ni; Jianan Zhang; Dazhi Tan; Hiroaki Wakimoto; Daniel P. Cahill; Xiaochen Bai; Xuelian Luo; John M. Asara; Sriram Subramaniam; Yibing Shan; Xu Wu
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Local therapy with hypoxia-targeting radiopharmaceutical [64Cu]Cu-ATSM in high-grade glioma patient-derived xenograft models使用缺氧靶向放射性药物[64Cu]Cu-ATSM进行局部治疗，在高级别胶质瘤患者来源的异种移植模型中。
errRadiotherapy and Oncology
IF5.3
err2025-12-07
err0
PREAI
errYukie Yoshii; Fukiko Hihara; Hiroki Matsumoto; Chika Igarashi; Tomoko Tachibana; Mitsuhiro Shinada; Makoto Ohtake; Hisashi Suzuki; Ming-Rong Zhang; Akito Oshima; Tomohiro Kaneta; Nobuhiro Nitta; Sayaka Shibata; Hidemitsu Sato; Kimiteru Ito; Yoshitaka Narita; Daniel P. Cahill; Hiroaki Wakimoto; Ukihide Tateishi; Hiroaki Kurihara
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Leveraging the cGAS-STING pathway to modulate the tumor microenvironment and enhance immunotherapies in glioblastoma利用cGAS-STING通路调节肿瘤微环境并增强胶质母细胞瘤的免疫疗法
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errLeparc, Louise; Gil, Judit Sanchez; Sadzot-Delvaux, Catherine; Rogister, Bernard; Rabkin, Samuel; Neirinckx, Virginie; Wakimoto, Hiroaki
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Evaluation of a novel CNS penetrant YAP/TEAD-targeted therapy for lung cancer brain metastases一种新型中枢神经系统穿透性YAP/TEAD靶向疗法在肺癌脑转移中的应用评估
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errTorrini, Consuelo; Nayyar, Naema; Hagenbeek, Thijs; Yamazawa, Erika; Summers, Elizabeth; Maddalo, Danilo; Wakimoto, Hiroaki; Dey, Anwesha; Brastianos, Priscilla
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Oncolytic Herpes Simplex Virus Synergizes with DNA-PKcs Inhibitors to Treat Glioblastoma溶瘤单纯疱疹病毒与DNA-PKcs抑制剂协同治疗胶质母细胞瘤
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFudaba, Hirotaka; Wakimoto, Hiroaki; Martuza, Robert L.; Rabkin, Samuel D.
err分享
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Long-term treatment with mutant IDH inhibitor DS-1001b suppresses tumor growth and induces epigenetic reprogramming in IDH1-mutant gliomas长期使用突变IDH抑制剂DS-1001b可抑制IDH1突变型胶质瘤的生长并诱导其表观遗传重编程
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFujimoto, Kenji; Honda-Kitahara, Mai; Hattori, Naoko; Matsushita, Yuko; Hibiya, Yuko; Satomi, Kaishi; Matsunaga, Hironori; Tsutsumi, Shinji; Okamoto, Atsushi; Inoue, Tatsuya; Yamada, Makiko; Watanabe, Makoto; Wakimoto, Hiroaki; Onuki, Ritsuko; Kato, Mamoru; Sato, Taka-Aki; Ushijima, Toshikazu; Kitabayashi, Issay; Ichimura, Koichi
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Bcl-xL inhibition enhances the efficacy of Temozolomide by targeting senescent glioblastoma cellsBcl-xL抑制通过靶向衰老的胶质母细胞瘤细胞增强替莫唑胺的疗效
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errHiguchi, Fumi; Kiyokawa, Juri; Shin, Masahiro; Ueki, Keisuke; Cahill, Daniel; Wakimoto, Hiroaki
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err收藏
Generation of orthotopic patient-derived xenografts from progressive oligodendroglioma without TMZ-induced hypermutation原位患者来源异种移植物的产生，来自未经替莫唑胺诱导超突变的进展性少突胶质细胞瘤
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errNakano, Tomoyuki; Wakimoto, Hiroaki; Miller, Julie; Cahill, Daniel
err分享
err收藏
Investigating CDK2 and CDK4 Inhibition in IDH-Mutant Glioma with CDKN2A Deletion研究IDH突变型胶质瘤中CDK2和CDK4抑制及CDKN2A缺失的影响
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errDaware, Sayali; Wang, Yutong; Gowda, Rakshith; Nakano, Tomoyuki; Lanman, Tyler; Wakimoto, Hiroaki; Cahill, Daniel; Miller, Julie
err分享
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Dual inhibition of RAF/MEK and FAK signaling improves survival in intracranial meningioma modelsRAF/MEK和FAK信号通路的联合抑制可改善颅内脑膜瘤模型的生存率
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errIjad, Nazanin; Waller, Katie L.; Yamazawa, Erika; Nayyar, Naema; Torrini, Consuelo; Summers, Elizabeth J.; Migliarese, Christian; Marion, Braxton M.; Zhang, Britney S.; Sullivan, Emily; Ellington, Claudia; Sasisekharan, Varun; Carlson, Brett L.; Galanis, Evanthia; Sarkaria, Jann N.; Wakimoto, Hiroaki; Vaubel, Rachael A.; Brastianos, Priscilla K.
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Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells间皮素是一种存在于人类脑膜瘤表面的抗原，并且可以被CAR T细胞有效靶向。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errRamapriyan, Rishab; Barker, Fred; Richardson, Leland; Sun, Jing; Vandecandelaere, Gust; Shim, Jane; De Vlaminck, Guillaume; Gaffey, Matthew; Grewal, Eric; Tazhibi, Masih; Morshedy, Kourosh; Aref, Amir; Batool, Syeda; Guo, Xiaopeng; Ijad, Nazanin; Balaj, Leonora; Wakimoto, Hiroaki; Martinez-Lage, Maria; Frigault, Matthew; Leick, Mark; Bernstock, Joshua; Bi, Wenya Linda; Carter, Bob; Chiocca, E. Antonio; Dietrich, Jorg; Gerstner, Elizabeth; Boland, Genevieve; Nahed, Brian; Plotkin, Scott; Jenkins, Russell; Brastianos, Priscilla; Curry, William; Maus, Marcela; Choi, Bryan
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SUV-max of 68Ga-DOTATATE PET/CT correlates with WHO grade and RNA risk classification in meningioma68Ga-DOTATATE PET/CT的SUV-max与脑膜瘤的WHO分级和RNA风险分类相关。
errJournal of Neuro-Oncology
IF3.1
err2025-10-23
err0
PREAI
errLeihao Ren; Jiaojiao Deng; Juefeng Xu; Louman Chan; Qing Xie; Hiroaki Wakimoto; Ye Gong; Lingyang Hua
err分享
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Signal Amplification for Fluorescent Staining of Single Particles in Liquid Biopsies: Circulating Tumour Cells and Extracellular Vesicles液体活检中单粒子荧光染色的信号放大：循环肿瘤细胞和细胞外囊泡
errJournal of Extracellular Vesicles
IF14.5
err2025-10-08
err0
errOAAI
errSara Cavallaro; Sara I. Veiga; Raheel Ahmad; Berent Aldikacti; Mollie Bienstock; Diane Capen; Daniel C. Rabe; Uyen Ho; Dasol Lee; Daniel A. Ruiz-Torres; Hiroaki Wakimoto; Jorg Dietrich; Brian V. Nahed; Shannon L. Stott
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Photodynamic therapy using talaporfin sodium and semiconductor laser induces dose and time dependent cytocidal effect for human glioma derived stem cells使用talaporfin sodium和半导体激光的光动力疗法对人胶质瘤来源的干细胞产生剂量和时间依赖性的细胞毒性效应。
errPhotodiagnosis and Photodynamic Therapy
IF2.6
err2025-09-05
err0
errOAAI
errMegumi Ichikawa; Jiro Akimoto; Srivalleesha Mallidi; Hiroaki Wakimoto; Michihiro Kohno; Tayyaba Hasan
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研究方向

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合作学者
合作期刊
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Matthew Meyerson
H 指数: 223 · 论文数: 1.9K
R
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T
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H 指数: 181 · 论文数: 1.6K
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Patrick Y. Wen
H 指数: 145 · 论文数: 1.9K
D
David N. Louis
H 指数: 136 · 论文数: 635
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