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J

Jochen H.M. Prehn

Royal College of Surgeons in Ireland
H指数:78
被引数:2.9万

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荣誉奖项

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Advanced 3D patient-derived glioblastoma organoid-immune cell co-cultures reveal preserved MHC-I tumor cell surface expression and tumor cell-driven T-cell dysfunction

高级3D患者源性胶质母细胞瘤类器官-免疫细胞共培养揭示保留的MHC-I肿瘤细胞表面表达及肿瘤细胞驱动的T细胞功能障碍

Journal of Neuroinflammation
IF10.1
2026-09-110
OA
Mahsa Rezaeipour; Marta de Lucas Sanz; Hamed Allahverdi; Gaëlle Triballier; Eliane Klein; Ilaria Salvato; Pilar M. Moreno-Sanchez; Bakhtiyor Nosirov; Petr V. Nazarov; Batuhan Kisakol; Heiko Dussmann; Colum Connolly; Annette T. Byrne; Jochen H.M. Prehn; Dirk Brenner; Bassam Janji; Simone P. Niclou; Anna Golebiewska
Evaluating the NFPp10a/NF5310 glioblastoma model as a faithful avatar for screening tumour microenvironment–targeted therapies

评估NFPp10a/NF5310胶质母细胞瘤模型作为忠实替身用于筛选肿瘤微环境靶向疗法

Communications Biology
IF5.1
2026-09-040
OAAI
Kieron White; James Clerkin; Liam P. Shiels; Kieron Sweeney; Mohannad Dabbour; Alice C. O’Farrell; Maïté Verreault; Thomas Van Brussel; Ingrid Arijs; Suzanne Murphy; Evin M. Haworth; Christopher Van Hessche; Gautam Shankar; Joana Beyer; Patrick Dicker; Stephen G. Maher; Laure Marignol; Jack P. Gleeson; David O’Brien; Diether Lambrechts; Jochen H. M. Prehn; Ahmed Idbaih; Frederik De Smet; Kate Connor; Annette T. Byrne
Cell engulfment defines spatially distinct competitive metabolic niches associated with clinical outcomes in colorectal cancer

细胞吞噬定义了与结直肠癌临床结局相关且空间上不同的竞争性代谢生态位

cell death & differentiation
IF0
2026-06-300
OAAI
Emir Bozkurt; Batuhan Kisakol; Heiko Dussmann; Federico Lucantoni; Anna Sturrock; Mohammadreza Azimi; Sanghee Cho; Elizabeth McDonough; Joana Fay; Tony O’Grady; John P. Burke; Niamh McCawley; Deborah A. McNamara; Daniel B. Longley; Fiona Ginty; Jochen H. M. Prehn
Spatial analyses implicate high stromal tumour-infiltrating CD8+ lymphocytes as a negative predictive marker for chemotherapy in estrogen receptor-positive breast cancer

空间分析表明，高间质肿瘤浸润性CD8+淋巴细胞可作为雌激素受体阳性乳腺癌化疗的负预测标志物

Nature Communications
IF15.7
2026-06-230
OAAI
Zak Kinsella; Chowdhury Arif Jahangir; Hannah Nyarkoah Nyarko; Daria Kalinska-Lysiak; Claudia Aura Gonzalez; Verena Murphy; Tony O’Grady; Joanna Fay; Katherine Sheehan; Arman Rahman; John P. Crown; Catherine M. Kelly; Simon S. McDade; Ina Woods; Niamh M. C. Connolly; Jochen H. M. Prehn; William M. Gallagher; Darran P. O’Connor
A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer

一种基于机器学习的多模态数据融合方法流程，用于贝伐珠单抗治疗转移性结直肠癌的预后风险分析

Scientific Reports
IF3.9
2026-04-010
OAAI
Thomas, Valentina; Nyamundanda, Gift; Larkeryd, Adrian; Hari, P. S.; Miller, Ian S.; Venken, Tom; Smeets, Dominiek; Boeckx, Bram; Betge, Johannes; Ebert, Matthias P. A.; Gaiser, Timo; Murphy, Verena; Kay, Elaine; Verheul, Henk M.; O'Farrell, Alice C.; Cremolini, Chiara; Marmorino, Federica; Gallagher, William M.; Barat, Ana; Klinger, Rut; Fender, Bozena; Ylstra, Bauke; van Grieken, Nicole; McNamara, Deborah A.; Hennessy, Bryan T.; Das, Sudipto; Moran, Bruce; O'Connor, Darran P.; Dienstmann, Rodrigo; Lambrechts, Diether; Prehn, Jochen H. M.; Sadanandam, Anguraj; Byrne, Annette T.
Biofluid-specific variations in circulating 5′ transfer RNA fragments during ictal and interictal states in experimental temporal lobe epilepsy

实验性颞叶癫痫发作和发作间期状态下循环5′转移RNA片段的生物流体特异性变化

Epilepsia
IF6.6
2026-04-010
OAAI
Soukupova, Marie; Morrissey, Elena Perez; Guarino, Annunziata; Marino, Pietro; Pareo, Cristiana; Birtolo, Nicolo; Zaheer, Saad; Stewart, Rachel; Woods, Ina; Rosenow, Felix; Hamer, Hajo; Kortvelyessy, Peter; Pfeiffer, Shona; Henshall, David C.; Prehn, Jochen H. M.; Simonato, Michele
Androgen receptor localisation and protein interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer

雄激素受体定位和蛋白质相互作用为内分泌抵抗性乳腺癌中类固醇介导的代谢转变提供了见解。

npj Breast Cancer
IF7.6
2026-03-170
OAAI
Rachel Bleach; Emir Bozkurt; Jingqi Xin; Katherine M. Sheehan; Sally Shirran; Stephanie Agbana; Mihaela Ola; Leonie Young; Nicole S. Spoelstra; Jennifer K. Richer; Ana Cristina Vargas; Leonard D. Goldstein; Heloisa H. Milloli; Christine L. Chaffer; Michael W O’Reilly; Jochen HM Prehn; Marie McIlroy
Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain

贝伐珠单抗用于染色体不稳定性转移性结直肠癌：德国、爱尔兰和西班牙一种新型精准治疗方法的成本效益分析

PharmacoEconomics
IF4.6
2026-02-040
PRE
Jonathan Briody; Ian S. Miller; James F. O’Mahony; Lesley Tilson; Alice C. O’Farrell; Qiushi Chen; Verena Murphy; Orla Casey; Nadine Schulte; Matthias P. Ebert; Jochen H. M. Prehn; Diether Lambrechts; Bauke Ylstra; Rodrigo Dienstmann; Annette T. Byrne; Kathleen Bennett
Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin

粘液性结直肠癌中丝氨酸-精氨酸蛋白激酶1 (SRPK1) 表达下调，并可能介导奥沙利铂耐药性。

The Pharmacogenomics Journal
IF0
2025-10-030
OAAI
William P. Duggan; Mohammedreza Azimi; Lyndsey Flanagan; Graeme P. Sullivan; Ian. S. Reynolds; Joanna Fay; Heiko Dussmann; Tríona Ní Chonghaile; Katherine M. Sheehan; Karin Jirström; Jochen H. M. Prehn; John P. Burke

研究方向

暂未获取到该数据
H
Heiko Düßmann
H 指数:32论文数:83被引数:3,466
M
Markus Rehm
H 指数:59论文数:363被引数:2.6万
D
David C. Henshall
H 指数:67论文数:348被引数:1.4万
C
Caoimhín G. Concannon
H 指数:32论文数:103被引数:3,676
M
Manuela Salvucci
H 指数:19论文数:125被引数:1,177
D
Deborah A. McNamara
H 指数:34论文数:264被引数:3,792
D
Donat Kögel
H 指数:52论文数:165被引数:9,709
E
Elaine W. Kay
H 指数:46论文数:517被引数:8,022
A
Andreas U. Lindner
H 指数:15论文数:101被引数:726
T
Tobías Engel
H 指数:49论文数:206被引数:7,412