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G

Gabriele Margareta Siegler

paracelsus medical university
H指数:18
被引数:1,267

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Perioperative pembrolizumab, trastuzumab and FLOT in HER2-positive localized esophagogastric adenocarcinoma: a phase 2 trial

围手术期帕博利珠单抗、曲妥珠单抗及FLOT方案在HER2阳性局限性食管胃腺癌中的疗效：一项Ⅱ期临床试验

Nature Medicine
IF50
2025-10-180
OAAI
Alexander Stein; Eray Goekkurt; Salah-Eddin Al-Batran; Nicolas Moosmann; Thomas J. Ettrich; Thorsten Goetze; Barbara Gruen; Nils Homann; Sylvie Lorenzen; Ralf-Dieter Hofheinz; Viktor Rempel; Gabriele Siegler; Christian Müller; Benjamin Thiele; Tobias Broering; Mariana Santos Cruz; Claudia Pauligk; Mascha Binder; Joseph Tintelnot
Predictive criteria for overall survival and treatment duration of 2nd-line chemotherapy in patients with advanced pancreatic adenocarcinoma (AIO-PAK-0216)

预测性标准：晚期胰腺腺癌患者二线化疗的总体生存期和治疗持续时间（AIO-PAK-0216）

British Journal of Cancer
IF6.8
2025-10-140
OA
Manfred P. Lutz; Nikolaus Ansorge; Gleb Barmashenko; Hans Bauer; Christof Burkart; Thomas Decker; Thomas Ettrich; Ludwig Fischer von Weikersthal; Thomas Geer; Anke Gerhardt; Sabine Höfling; Lutz Jacobasch; Michael Koenigsmann; Tobias Leidig; Ruben Plentz; Sebastian Räth; Dietmar Reichert; Markos Schulte; Nadine Schulte; Andreas Schwarzer; Gabriele Siegler; Dirk Waldschmidt; Meinolf Karthaus
Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113) (vol 7, 100552, 2024)
ESMO OPEN
IF8.3
2024-10-010
OAAI
Hartlapp, I.; Valta-Seufzer, D.; Siveke, J. T.; Alguel, H.; Goekkurt, E.; Siegler, G.; Martens, U. M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T. J.; Held, S.; Keller, R.; Anger, F.; Germer, C. T.; Stang, A.; Kimmel, B.; Heinemann, V.; Kunzmann, V.
Nab-paclitaxel/gemcitabine with or without epigenetic targeting followed by consolidating immune targeting with durvalumab and lenalidomide in patients with advanced pancreatic ductal adenocarcinoma: Results from the SEPION/AIO-PAK-0118 phase I/II study

Nab-紫杉醇/吉西他滨联合或不联合表观遗传靶向治疗，随后进行durvalumab和lenalidomide巩固性免疫靶向治疗，用于晚期胰腺导管腺癌患者：SEPION/AIO-PAK-0118 I/II期研究的结果

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Siveke, J. T.; Sinn, M.; Dorman, K.; Siegler, G. M.; Seufferlein, T.; Trojan, J.; Waldschmidt, D. T.; Koenig, A. O.; Schipp, D.; Liffers, S-T.; Kunzmann, V.
Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113) (vol 7, 100552, 2024)
ESMO OPEN
IF8.3
2024-05-011
OAAI
Hartlapp, I.; Valta-Seufzer, D.; Siveke, J. T.; Alguel, H.; Goekkurt, E.; Siegler, G.; Martens, U. M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T. J.; Held, S.; Keller, R.; Anger, F.; Germer, C. T.; Stang, A.; Kimmel, B.; Heinemann, V.; Kunzmann, V.
ASO Visual Abstract: Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer-The Randomized Multicenter Phase II NEPAFOX Trial
ANNALS OF SURGICAL ONCOLOGY
IF3.5
2024-04-040
PRE
Goetze, Thorsten O.; Reichart, Alexander; Bankstahl, Ulli S.; Pauligk, Claudia; Loose, Maria; Kraus, Thomas W.; Elshafei, Moustafa; Bechstein, Wolf O.; Trojan, Joerg; Behrend, Matthias; Homann, Nils; Venerito, Marino; Bohle, Wolfram; Varvenne, Michael; Bolling, Claus; Behringer, Dirk M.; Kratz-Albers, Karsten; Siegler, Gabriele M.; Hozaeel, Wael; Al-Batran, Salah-Eddin
Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: The Randomized Multicenter Phase II NEPAFOX Trial
ANNALS OF SURGICAL ONCOLOGY
IF3.5
2024-03-085
OAAI
Goetze, Thorsten O.; Reichart, Alexander; Bankstahl, Ulli S.; Pauligk, Claudia; Loose, Maria; Kraus, Thomas W.; Elshafei, Moustafa; Bechstein, Wolf O.; Trojan, Joerg; Behrend, Matthias; Homann, Nils; Venerito, Marino; Bohle, Wolfram; Varvenne, Michael; Bolling, Claus; Behringer, Dirk M.; Kratz-Albers, Karsten; Siegler, Gabriele M.; Hozaeel, Wael; Al-Batran, Salah-Eddin
Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarcinoma-a phase II trial of the AIO study group (AIO STO 0321)

Pembrolizumab和曲妥珠单抗联合FLOT用于HER2-positive局部食管胃腺癌的围手术期治疗-AIO研究组 (AIO STO 0321) 的II期试验

FRONTIERS IN ONCOLOGY
IF3.3
2023-10-163
OAAI
Tintelnot, Joseph; Stein, Alexander; Al-Batran, Salah-Eddin; Ettrich, Thomas; Goetze, Thorsten; Gruen, Barbara; Haag, Georg Martin; Heuer, Vera; Hofheinz, Ralf-Dieter; Homann, Nils; Broering, Tobias Sebastian; Cruz, Mariana Santos; Kurreck, Annika; Lorenzen, Sylvie; Moosmann, Nicolas; Mueller, Christian; Schuler, Markus; Siegler, Gabriele; Binder, Mascha; Goekkurt, Eray
Perioperative FLOT plus ramucirumab for resectable esophagogastric adenocarcinoma: A randomized phase II/III trial of the German AIO and Italian GOIM
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2023-03-2313
PRE
Goetze, Thorsten O.; Hofheinz, Ralf-Dieter; Gaiser, Timo; Schmalenberg, Harald; Strumberg, Dirk; Goekkurt, Eray; Angermeier, Stefan; Zander, Thomas; Kopp, Hans G.; Pink, Daniel; Siegler, Gabriele; Schenk, Michael; de Vita, Ferdinando; Galizia, Gennaro; Maiello, Evaristo; Bechstein, Wolf O.; Elshafei, Moustafa; Loose, Maria; Sookthai, Disorn; Brulin, Tanita; Pauligk, Claudia; Homann, Nils; Al-Batran, Salah-Eddin
Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113)
ESMO OPEN
IF8.3
2022-08-0122
OAAI
Hartlapp, I; Valta-Seufzer, D.; Siveke, J. T.; Algul, H.; Goekkurt, E.; Siegler, G.; Martens, U. M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T. J.; Held, S.; Keller, R.; Anger, F.; Germer, C. T.; Stang, A.; Kimmel, B.; Heinemann, V; Kunzmann, V
Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multi-agent induction chemotherapy: Results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113)
ANNALS OF ONCOLOGY
IF65.4
2021-09-011
OAAI
Hartlapp, I.; Valta-Seufzer, D.; Siveke, J.; Alguel, H.; Goekkurt, E.; Siegler, G. M.; Martens, U. M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T. J.; Held, S.; Keller, R.; Anger, F.; Germer, C-T.; Stang, H. A.; Heinemann, V.; Kunzmann, V.
Nab-paclitaxel plus gemcitabine versus nab-paclitaxel plus gemcitabine followed by FOLFIRINOX induction chemotherapy in locally advanced pancreatic cancer (NEOLAP-AIO-PAK-0113): a multicentre, randomised, phase 2 trial
LANCET GASTROENTEROLOGY & HEPATOLOGY
IF38.6
2021-02-01136
PREAI
Kunzmann, Volker; Siveke, Jens T.; Alguel, Hana; Goekkurt, Eray; Siegler, Gabriele; Martens, Uwe; Waldschmidt, Dirk; Pelzer, Uwe; Fuchs, Martin; Kullmann, Frank; Boeck, Stefan; Ettrich, Thomas J.; Held, Swantje; Keller, Ralph; Klein, Ingo; Germer, Christoph-Thomas; Stein, Hubert; Friess, Helmut; Bahra, Marcus; Jakobs, Ralf; Hartlapp, Ingo; Heinemann, Volker
Quality of life and outcome of patients with metastatic pancreatic cancer receiving first-line chemotherapy with nab-paclitaxel and gemcitabine: Real-life results from the prospective QOLIXANE trial of the Platform for Outcome, Quality of Life and Translational Research on Pancreatic Cancer registry
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2020-10-2311
OAAI
Al-Batran, Salah-Eddin; Hofheinz, Ralf-Dieter; Reichart, Alexander; Pauligk, Claudia; Schoenherr, Caroline; Schlag, Rudolf; Siegler, Gabriele; Doerfel, Steffen; Koenigsmann, Michael; Zahn, Mark-Oliver; Schubert, Joerg; Aldaoud, Ali; Hoeffkes, Heinz-Gert; Schulz, Holger; Hahn, Lars; Uhlig, Jens; Blau, Wolfgang; Stauch, Martina; Weniger, Joerg; Wolf, Martin; Jacobasch, Lutz; Bildat, Stephan; Wehmeyer, Juergen; Homann, Nils; Trojan, Joerg; Waidmann, Oliver; Fietz, Thomas; Feustel, Hans-Peter; Groschek, Matthias; Wierecky, Jan; Waibel, Karin; Mahlmann, Stefan; Schwindel, Uwe; Peters, Uwe; Schuch, Gunter; Pink, Daniel; Eschenburg, Henning; Woerns, Marcus-A.; Harich, Hans-Detlev; von Weikersthal, Ludwig Fischer; Daessler, Klaus-Ulrich; Behringer, Dirk M.; Messmann, Helmut; Kretzschmar, Albrecht; Gallmeier, Eike; Forstbauer, Helmut; Kunzmann, Volker; Papke, Jens; Buechner-Steudel, Petra; Vehling-Kaiser, Ursula; Springfeld, Christoph; Vogel, Arndt; Ettrich, Thomas J.; Schaaf, Marina; zur Hausen, Gerrit; Goetze, Thorsten Oliver
Safety analysis of the run-in phase (1st and 2nd cohort) of the IMMUNIB trial (AIO-HEP-0218/ass) - An open-label, single-arm phase II study evaluating safety and efficacy of immunotherapy with nivolumab in combination with lenvatinib in advanced stage HCC
ANNALS OF ONCOLOGY
IF65.4
2020-09-012
PREAI
Vogel, A.; Mueller, D. W.; De Toni, E.; Siegler, G. M.; Siebler, J.; Lindig, U.; Mueller, T.; Schultheiss, M.; Geissler, M.; Krammer-Steiner, B.; Reichart, A.; Lammert, F.; Prause, C.; Walker, M.; Al-Batran, S-E.; Kosic, N.
The QOLIXANE trial - Real life QoL and efficacy data in 1st line pancreatic cancer from the prospective platform for outcome, quality of life, and translational research on pancreatic cancer (PARAGON) registry
ANNALS OF ONCOLOGY
IF65.4
2020-09-011
OAAI
Goetze, T. O.; Hofheinz, R. D.; Reichart, A.; Pauligk, C.; Schlag, R.; Siegler, G. M.; Hoeffkes, H-G.; Blau, W.; Homann, N.; Trojan, J.; Waidmann, O.; Pink, D.; Messmann, H.; Kunzmann, V.; Vogel, A.; Ettrich, T. J.; Schoenherr, C.; Schaaf, M.; zur Hausen, G.; Al-Batran, S-E.
Final results and subgroup analysis of the PETRARCA randomized phase II AIO trial: Perioperative trastuzumab and pertuzumab in combination with FLOT versus FLOT alone for HER2 positive resectable esophagogastric adenocarcinoma
ANNALS OF ONCOLOGY
IF65.4
2020-09-0119
OAAI
Al-Batran, S-E.; Haag, G. M.; Ettrich, T. J.; Borchert, K.; Kretzschmar, A.; Teschendorf, C.; Siegler, G. M.; Ebert, M.; Goekkurt, E.; Welslau, M. K.; Mahlberg, R. J. C.; Homann, N.; Pink, D.; Bechstein, W. O.; Reichardt, P.; Gaiser, T.; Sookthai, D.; Pauligk, C.; Goetze, T. O.; Hofheinz, R. D.

研究方向

暂未获取到该数据
T
Thomas J. Ettrich
H 指数:35论文数:300被引数:4,608
E
Eray Goekkurt
H 指数:30论文数:215被引数:9,444
N
Nils Homann
H 指数:38论文数:236被引数:1.0万
C
Claudia Pauligk
H 指数:34论文数:253被引数:8,463
D
Dirk Waldschmidt
H 指数:25论文数:151被引数:3,742
R
Ralf‐Dieter Hofheinz
H 指数:57论文数:606被引数:1.8万
J
Jens T. Siveke
H 指数:62论文数:743被引数:1.4万
S
Stefan Boeck
H 指数:46论文数:265被引数:7,463
M
Martin Fuchs
H 指数:38论文数:273被引数:7,978
D
Daniel Pink
H 指数:33论文数:238被引数:8,570