Brian J. Kirby - Publications, H-index & Citations

Brian J. Kirby

Orsobio

56H指数

296论文数

1.1W被引数

收录论文 79

发表时间

An oral, liver-restricted LXR inverse agonist for dyslipidemia: preclinical development and phase 1 trial 口服，肝脏限制性LXR反向激动剂治疗血脂异常: 临床前开发和1期试验

Nature Medicine

IF50

2026-01-16

OAAI

Xiaoxu Li; Giorgia Benegiamo; Archana Vijayakumar; Natalie Sroda; Masaki Kimura; Ryan S. Huss; Steve Weng; Eisuke Murakami; Brian J. Kirby; Giacomo V. G. von Alvensleben; Claus Kremoser; Edward J. Gane; Takanori Takebe; Robert P. Myers; G. Mani Subramanian; Johan Auwerx

Red blood cell entrapment in thrombi formed under pathological flow: Stiffness and binding antigens impact thrombus morphology and cell distribution 病理性血流下血栓中红细胞的捕获：刚度和结合抗原影响血栓形态和细胞分布

Acta Biomaterialia

IF9.6

2025-05-23

PREAI

Anjana Jayaraman; Junhyuk Kang; Purvil Jani; Nicholas L. Abbott; James F. Antaki; Brian J. Kirby

Effects of exercise on inflammation, circulating tumor cells, and circulating tumor DNA in colorectal cancer 运动对炎症、循环肿瘤细胞和循环肿瘤DNA的影响

Journal of Sport and Health Science

IF10.3

2025-03-17

OAAI

Justin C. Brown; Stephanie L.E. Compton; Andrew Kang; Anjana Jayaraman; L. Anne Gilmore; Brian J. Kirby; Frank L. Greenway; Shengping Yang; Guillaume Spielmann

Programmable viscosity metamaterials: Designing fluid properties using temporal superposition of shear and acoustics

PHYSICAL REVIEW RESEARCH

IF4.2

2024-11-05

PREAI

Sehgal, Prateek; Ramaswamy, Meera; Ong, Edward Y. X.; Ness, Christopher; Cohen, Itai; Kirby, Brian J.

Safety, PK, and Preliminary Efficacy of the Liver-Targeted Mitochondrial Protonophore TLC-6740-A Phase 1 Study

DIABETES

IF7.5

2024-06-14

PREAI

Gane, Edward; Huss, Ryan S.; Sur, Jane; Murakami, Eisuke; Weng, Steve; Kirby, Brian J.; Shah, Amrik; Shulman, Gerald I.; Subramanian, Mani; Vijayakumar, Archana; Myers, Robert P.

Shear Histories Alter Local Shear Effects on Thrombus Nucleation and Growth 剪切历史改变了局部剪切对血栓成核和生长的影响

ANNALS OF BIOMEDICAL ENGINEERING

IF5.4

2024-02-06

PREAI

Kang, Junhyuk; Jayaraman, Anjana; Antaki, James F.; Kirby, Brian

Safety, Pharmacokinetics, and Lipid Lowering Effects of the Oral, Liver- Targeted Liver X Receptor (LXR) Inverse Agonist TLC2716 in Healthy Volunteers 口服肝靶向肝X受体 (LXR) 反向激动剂TLC2716在健康志愿者中的安全性，药代动力学和降脂作用

CIRCULATION

IF38.6

2023-11-07

PREAI

Gane, Edward J.; Huss, Ryan S.; Sur, Jane; Weng, Steve; Murakami, Eisuke; Vijayakumar, Archana; Kirby, Brian J.; Subramanian, G. Mani; Myers, Robert P.

HER2-low expression in patients with advanced or metastatic solid tumors 晚期或转移性实体瘤患者的HER2-low表达

ANNALS OF ONCOLOGY

IF65.4

2023-11-01

PREAI

Uzunparmak, B.; Haymaker, C.; Masciari, S.; Wang, L.; Lin, H.; Gorur, A.; Kirby, B.; Cimo, A. -m.; Kennon, A.; Ding, Q.; Urschel, G.; Yuan, Y.; Feng, G.; Rizvi, Y.; Hussain, A.; Zhu, C.; Kim, P.; Abbadessa, G.; Subbiah, V.; Yap, T. A.; Rodon, J.; Piha-Paul, S. A.; Meric-Bernstam, F.; Dumbrava, E. E.

Extracting Mural and Volumetric Growth Patterns of Platelet Aggregates on Engineered Surfaces by Use of an Entity Tracking Algorithm

ASAIO JOURNAL

IF2.3

2022-10-27

OAAI

Kang, Junhyuk; Jayaraman, Anjana; Antaki, James F.; Kirby, Brian J.

Editorial: protecting hypoxia-inducible factor 1a and gut integrity with GB004-a promising therapeutic approach for ulcerative colitis? Authors' reply

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2022-03-04

PREAI

Danese, Silvio; Levesque, Barrett G.; Feagan, Brian G.; Jucov, Alina; Bhandari, B. R.; Pai, Rish K.; Meadows, Kristen Taylor; Kirby, Brian J.; Bruey, Jean-Marie; Olson, Allan; Osterhout, Robin; Van Biene, Courtney; Ford, Julia; Aranda, Richard; Raghupathi, Kartik; Sandborn, William J.

Randomised clinical trial: a phase 1b study of GB004, an oral HIF-1α stabiliser, for treatment of ulcerative colitis

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2022-01-10

OAAI

Danese, Silvio; Levesque, Barrett G.; Feagan, Brian G.; Jucov, Alina; Bhandari, Bal Raj; Pai, Rish K.; Meadows, Kristen Taylor; Kirby, Brian J.; Bruey, Jean-Marie; Olson, Allan; Osterhout, Robin; Van Biene, Courtney; Ford, Julia; Aranda, Richard; Raghupathi, Kartik; Sandborn, William J.

Ledipasvir/Sofosbuvir for 8, 12, or 24 Weeks in Hepatitis C Patients Undergoing Dialysis for End-Stage Renal Disease

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2021-05-05

PREAI

Chuang, Wan-Long; Hu, Tsung-Hui; Buggisch, Peter; Moreno, Christophe; Su, Wei-Wen; Biancone, Luigi; Camargo, Marianne; Hyland, Robert; Lu, Sophia; Kirby, Brian J.; Dvory-Sobol, Hadas; Osinusi, Anu; Gaggar, Anuj; Peng, Cheng-Yuan; Liu, Chen-Hua; Sise, Meghan E.; Mangia, Alessandra

Physiologically-Based Pharmacokinetic Modeling of Remdesivir and Its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients With COVID-19

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2021-03-10

OAAI

Lutz, Justin D.; Mathias, Anita; German, Polina; Pikora, Cheryl; Reddy, Sunila; Kirby, Brian J.

Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2020-11-25

PREAI

Kirby, Brian J.; Lutz, Justin D.; Yue, Mun Sang; Garrison, Kimberly L.; Qin, Ann Ran-Ran; Ampaw, Lorraine; Beysen, Carine; Myers, Robert P.; Kearney, Brian P.; Mathias, Anita

Sofosbuvir plus ribavirin and sofosbuvir plus ledipasvir in patients with genotype 1 or 3 hepatitis C virus and severe renal impairment: a multicentre, phase 2b, non-randomised, open-label study

LANCET GASTROENTEROLOGY & HEPATOLOGY

IF38.6

2020-10-01

PREAI

Lawitz, Eric; Landis, Charles S.; Flamm, Steven L.; Bonacini, Maurizio; Ortiz-Lasanta, Grisell; Huang, Jonathan; Zhang, Jie; Kirby, Brian J.; De-Oertel, Shampa; Hyland, Robert H.; Osinusi, Anu O.; Brainard, Diana M.; Robson, Richard; Maliakkal, Benedict J.; Gordon, Stuart C.; Gane, Edward J.

Three-Dimensional Numerical Modeling of Surface-Acoustic-Wave Devices: Acoustophoresis of Micro- and Nanoparticles Including Streaming 表面声波器件的三维数值建模: 包括流的微米和纳米颗粒的声泳

PHYSICAL REVIEW APPLIED

IF4.4

2019-10-14

OAAI

Skov, Nils R.; Sehgal, Prateek; Kirby, Brian J.; Bruus, Henrik

Sofosbuvir/velpatasvir for 12 weeks in hepatitis C virus-infected patients with end-stage renal disease undergoing dialysis

JOURNAL OF HEPATOLOGY

IF33

2019-10-01

111

OAAI

Borgia, Sergio M.; Dearden, Janet; Yoshida, Eric M.; Shafran, Stephen D.; Brown, Ashley; Ben-Ari, Ziv; Cramp, Matthew E.; Cooper, Curtis; Foxton, Matthew; Fernandez Rodriguez, Conrado; Esteban, Rafael; Hyland, Robert; Lu, Sophia; Kirby, Brian J.; Meng, Amy; Markova, Svetlana; Dvory-Sobol, Hadas; Osinusi, Anu O.; Bruck, Rafael; Ampuero, Javier; Ryder, Stephen D.; Agarwal, Kosh; Fox, Raymond; Shaw, David; Haider, Shariq; Willems, Bernard; Lurie, Yoav; Calleja, Jose Luis; Gane, Edward J.

Scalable Synthesis of Switchable Assemblies of Gold Nanorod Lyotropic Liquid Crystal Nanocomposites 金纳米棒溶致液晶纳米复合材料的可切换组件的可扩展合成

SMALL

IF12.1

2019-04-25

PREAI

Liu, Xiao; Qi, Genggeng; Park, Albert Min Gyu; Rodriguez-Gonzalez, Arnaldo; Enotiadis, Apostolos; Pan, Wenyang; Kosma, Vasiliki; Fuchs, Gregory D.; Kirby, Brian J.; Giannelis, Emmanuel P.

Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2018-05-01

OAAI

Babusis, Darius; Curry, Michael P.; Kirby, Brian; Park, Yeojin; Murakami, Eisuke; Wang, Ting; Mathias, Anita; Afdhal, Nezam; McHutchison, John G.; Ray, Adrian S.

Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2018-04-26

OAAI

Lutz, Justin D.; Kirby, Brian J.; Wang, Lu; Song, Qinghua; Ling, John; Massetto, Benedetta; Worth, Angela; Kearney, Brian P.; Mathias, Anita

研究方向