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Laura M. Spring

mass general brig ham cancer institute
H指数:36
被引数:6,832

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Metastatic metaplastic triple negative breast cancer response to sacituzumab govitecan and biomarker targetability

转移性化生性三阴性乳腺癌对沙库巴曲珠单抗的应答及生物标志物靶向性

2026-09-300
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Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer

来自12,827例转移性乳腺癌患者循环DNA中可操作的遗传景观和动态

2026-09-220
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Safety and antitumour activity of ipatasertib combined with endocrine therapy and a CDK4/6 inhibitor in HR+/HER2– metastatic breast cancer (TAKTIC): a single-centre, open-label, phase 1b trial

伊帕西替布联合内分泌疗法和CDK4/6抑制剂在HR+/HER2–转移性乳腺癌中的安全性和抗肿瘤活性(TAKTIC):一项单中心、开放标签、1b期临床试验

2026-04-270
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Effectiveness of sacituzumab govitecan and management of neutropenia in patients with metastatic triple-negative breast cancer treated in real-world settings in the United States

曲拉留单抗 govitecan 的有效性及在美国真实世界环境中治疗转移性三阴性乳腺癌患者的中性粒细胞减少症管理

2025-06-010
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Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2- breast cancer (LEADER)
2025-01-070
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Real-world evidence on risk of recurrence (ROR) in patients (pts) with node-negative (N0) and node-positive HR+/HER2-early breast cancer (EBC) from US electronic health records (EHR)

来自美国电子健康记录(EHR)的关于淋巴结阴性(N0)和淋巴结阳性人表皮生长因子受体2阴性(HR+/HER2-)早期乳腺癌(EBC)患者复发风险(ROR)的真实世界证据

2024-09-012
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Real-world use patterns, effectiveness, and tolerability of sacituzumab govitecan for second-line and later-line treatment of metastatic triple-negative breast cancer in the United States

sacituzumab govitecan在美国转移性三阴性乳腺癌二线和后线治疗中的实际使用模式,有效性和耐受性

2024-06-213
OAAI
Antibody-Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer

抗体药物偶联物Sacituzumab Govitecan可在乳腺癌患者中实现序贯TOP1/PARP抑制剂治疗策略

2024-05-066
OAAI
Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations
2024-05-020
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Neoadjuvant HER2-targeted Therapy plus /Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial
2024-05-020
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Event-free Survival by Residual Cancer Burden (RCB) and Intratumor HER2 Heterogeneity after Neoadjuvant T-DM1 and Pertuzumab for Early-stage HER2-positive Breast Cancer
2024-05-020
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