Kun‐Che Chang - Publications, H-index & Citations

Kun‐Che Chang

upmc vision institute

28H指数

108论文数

2.0K被引数

收录论文 45

发表时间

Pou2f2 enhances retinal ganglion cell survival and axon regeneration after optic nerve injury Pou2f2在视神经损伤后增强视网膜神经节细胞存活和轴突再生

npj Regenerative Medicine

IF6.5

2026-10-14

OAAI

Dimitrios Stavropoulos; Chia-Chun Liu; Shining Wang; Chi-Yu Chen; Mishal Rao; Laman Mirzaliyeva; Hui-Chun Cheng; Ya-Ling Lin; Andrew M. Williams; Yuan Pan; Takaaki Kuwajima; Jeffrey L. Goldberg; José-Alain Sahel; Kun-Che Chang

Retinal ganglion cell-derived vesicles: A new path to neuroprotection 视网膜神经节细胞来源的囊泡：神经保护的新途径

Molecular Therapy

IF12

2026-09-01

PREAI

Kun-Che Chang

Enzymatic Disruption of the Internal Limiting Membrane Enhances Transplanted Retinal Ganglion Cell Survival 酶解破坏内界膜增强移植视网膜神经节细胞存活

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2026-01-01

PREAI

Stavropoulos, Dimitrios; Liu, Chia-Chun; Chen, Chi-Yu; Mirzaliyeva, Laman; Rao, Mishal; Wang, Shining; Zhao, Chengcheng; Lin, Ya-Ling; Talebian, Niki; Rosin, Boris; Lo, Jung; Pi, Shaohua; Johnson, Thomas, V; Sahel, Jose-Alain; Chang, Kun-Che

CARBOPLATIN IMPAIRS OPTIC NERVE MYELINATION IN NEUROFIBROMATOSIS TYPE 1 (NF1) BY REDUCING CHOLESTEROL LEVELS AND INDUCING OLIGODENDROCYTE LOSS 卡铂通过降低胆固醇水平和诱导少突胶质细胞丢失，损害神经纤维瘤病1型（NF1）视神经的髓鞘化。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Aghoghovwia, Benjamin; El-Toukhy, Hana; Hamblett, Ava; Chandramouli, Varsha; Ban, Kechen; Stavropoulos, Dimitrios; Wei, Bo; Lorenzi, Philip; Chang, Kun-Che; Mahalingam, Rajasekaran; Pan, Yuan

The distinct roles of TGF-β signaling in retinal development TGF-β信号在视网膜发育中的不同作用

iScience

IF4.1

2025-10-10

OAAI

Chi-Yu Chen; Chia-Chun Liu; Dimitrios Stavropoulos; Pei-Kang Liu; Yu-Chih Chen; Shining Wang; Mishal Rao; Catalina Sun; Ying Zhu; Ziming Luo; Evan G. Cameron; Jeffrey L. Goldberg; Kun-Che Chang

3D-printed plugs enhance cell usage efficiency for single-cell migration and neuron axon guidance assays 3D打印的塞子提高了单细胞迁移和神经元轴突导向实验中的细胞使用效率。

Cell Reports Methods

IF4.5

2025-07-28

OAAI

Jinxiong Cheng; Edwin C. Rock; Mishal Rao; Hsiao-Chun Chen; Yushu Ma; Kun-Che Chang; Yu-Chih Chen

Sodium Silicate Complex Reduces Subdermal Hemorrhage and Prolongs Survival After Envenomation by Trimeresurus stejnegeri stejnegeri 硅酸钠复合物可减少三棱蛇毒液注射后的皮下出血并延长存活时间。

toxicon x

IF2.4

2025-07-14

PREAI

Yen-Chia Chen; Hao-Ming Chang; Chang-Chih Ke; Chia-Chun Liu; Yu-Kai Huang; Kun-Che Chang; Min-Hui Chen; Isaac Chun-Jen Chen; Yu-Wei Chiang; Po-Yu Liu; Chih-Sheng Lai; Kuo-Lung Lai; Yan-Chiao Mao

Anti-cancer effects of Psoralea corylifolia: insights into cancer hallmarks 补骨脂的抗癌效应：对癌症特征的认识

Phytochemistry Reviews

IF7.6

2025-07-14

PREAI

Pin-Rong Chen; Tz-Syuan Su; Kun-Che Chang; Chien-Chih Chiu; Shu-Pin Huang; Hsin-Chih Yeh; Shu-Chi Wang; Chia-Yang Li

Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk

STEM CELL RESEARCH & THERAPY

IF7.3

2025-02-25

OAAI

Xia, Qing; Chang, Kun-Che; Sun, Yanan; Nahmou, Michael; Noro, Takahiko; Cheng, Yun; Kong, Xiangmei; Mo, Xiaofen; Goldberg, Jeffrey L.; Wu, Suqian

Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regeneration

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-12-29

OAAI

Rao, Mishal; Luo, Ziming; Liu, Chia-Chun; Chen, Chi-Yu; Wang, Shining; Nahmou, Michael; Tanasa, Bogdan; Virmani, Aman; Byrne, Leah; Goldberg, Jeffrey L.; Sahel, Jose-Alain; Chang, Kun-Che

Glaucine inhibits hypoxia-induced angiogenesis and attenuates LPS-induced inflammation in human retinal pigment epithelial ARPE-19 cells

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2024-10-01

PREAI

Chen, Ting-En; Lo, Jung; Huang, Shu-Pin; Chang, Kun-Che; Liu, Po-Len; Wu, Hsin-En; Chen, Yuan-Ru; Chang, Yo-Chen; Liu, Ching-Chih; Lee, Po-Yen; Lai, Yu-Hung; Wu, Pei-Chang; Wang, Shu-Chi; Li, Chia-Yang

Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Chen, Chih-Yi; Huang, Yu-Ching; Su, Wen-Hsiu; Liu, Yi-Ting; Chen, Chi-Sheng; Li, Chia-Yang; Chang, Kun-Che; Dai, Chia-Yen; Wang, Shu-Chi

Therapeutic strategies for glaucoma and optic neuropathies

MOLECULAR ASPECTS OF MEDICINE

IF10.3

2023-12-01

OAAI

Lo, Jung; Mehta, Kamakshi; Dhillon, Armaan; Huang, Yu-Kai; Luo, Ziming; Nam, Mi-Hyun; Al Diri, Issam; Chang, Kun-Che

Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

LIFE SCIENCES

IF5.1

2023-10-01

PREAI

Chien, Hsin-Tung; Li, Chia-Yang; Su, Wen-Hsiu; Chang, Kun-Che; Chen, Chi-Sheng; Liu, Yi-Ting; Chen, Chih-Yi; Dai, Chia-Yen; Wang, Shu-Chi

Analyzing effectiveness and safety of standard-dose and low- dose bevacizumab combination with atezolizumab in patients with unresectable hepatocellular carcinoma: a multi-institutional study in Taiwan

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

OAAI

Wang, Y-L.; Chen, W-T.; Huang, M-Y.; Chang, K-C.

Cell replacement with stem cell-derived retinal ganglion cells from different protocols

NEURAL REGENERATION RESEARCH

IF6.7

2023-07-20

OAAI

Luo, Ziming; Chang, Kun-Che

Cilia-associated wound repair mediated by IFT88 in retinal pigment epithelium

SCIENTIFIC REPORTS

IF3.9

2023-05-21

OAAI

Ning, Ke; Bhuckory, Mohajeet B.; Lo, Chien-Hui; Sendayen, Brent E.; Kowal, Tia J.; Chen, Ming; Bansal, Ruchi; Chang, Kun-Che; Vollrath, Douglas; Berbari, Nicolas F.; Mahajan, Vinit B.; Hu, Yang; Sun, Yang

Aldose reductase inhibition decelerates optic nerve degeneration by alleviating retinal microglia activation 醛糖还原酶抑制通过减轻视网膜小胶质细胞活化来减缓视神经变性

SCIENTIFIC REPORTS

IF3.9

2023-04-05

OAAI

Rao, Mishal; Huang, Yu-Kai; Liu, Chia-Chun; Meadows, Chandler; Cheng, Hui-Chun; Zhou, Mengli; Chen, Yu-Chih; Xia, Xin; Goldberg, Jeffrey L.; Williams, Andrew M.; Kuwajima, Takaaki; Chang, Kun-Che

Directly induced human retinal ganglion cells mimic fetal RGCs and are neuroprotective after transplantation in vivo 直接诱导的人视网膜神经节细胞模拟胎儿rgc，在体内移植后具有神经保护作用

STEM CELL REPORTS

IF5.1

2022-12-01

OAAI

Luo, Ziming; Chang, Kun-Che; Wu, Suqian; Sun, Catalina; Xia, Xin; Nahmou, Michael; Bian, Minjuan; Wen, Rain R.; Zhu, Ying; Shah, Sahil; Tanasa, Bogdan; Wernig, Marius; Goldberg, Jeffrey L.

EXPLORE-LC: A multi-site real-world evidence research platform for non-small cell lung cancer in Asia-Pacific

ANNALS OF ONCOLOGY

IF65.4

2022-11-01

OAAI

Toh, K. C.; Zhao, X.; Kim, J. H.; Stratton, G.; Lin, H-W.; Lee, D. H.; Yoon, S.; Fang, Y-F.; Chang, K-C.; Stirling, R. G.; Zalcberg, J. R.; Jung, H. A.; Yu, H. Y.; Lim, S. M.; Lim, S.; Chou, K-P.; Kim, J. A.; Patel, D.; Kleinman, N.

研究方向